Selective Cox-2 Inhibitor (meloxicam) And Tooth-supporting Bone Quality. A Histomorphometric Study In Rats

The effects of the non-steroidal anti-inflammatory drugs (NSAIDs) on bone quantity and quality were investigated for years. However, there is lack of information on the impact of NSAIDs on the quality of tooth-supporting alveolar bone in absence of periodontal inflammation. Thus, the aim of this study was to evaluate histometrically the influence of a selective COX-2 NSAID (Meloxicam) on the inter-radicular bone mineral density in rats. Forty-nine adult male Wistar rats were randomly divided into four experimental groups: Subcutaneous injection of 0.9% sterile saline for 15 days (G1; n=12) and 45 days (G2; n=11); and subcutaneous injection of Meloxicam for 15 days (G3; n=13) and 45 days (G4; n=13). Mineral density was histometrically determined in the inter-radicular area of the 1st mandibular molars and data analysis performed by two-way ANOVA (a=5%). Results showed no interaction between time and treatment (p>0.05) and that meloxicam did not affect the alveolar bone density. In contrast, it was found that inter-radicular alveolar bone density increased with time (91.88±3.08% and 92.86±2.38% for groups 15 and 45 days, respectively) (p<0.05). Within the limits of this study, daily administration of a selective COX-2 inhibitor (Meloxicam) did not affect the quality of the inter-radicular alveolar bone in absence of periodontal infection.28213513

COVID-19: Perspectives for the management of dental care and education

The rapid and abrupt transmission pattern of the SARS-CoV-2 unleashed the current COVID-19 pandemic, as recognized by the World Health Organization in March 2020. Considering the high risk of transmission of the virus in dental environments and the specificities in clinical practice, COVID-19 posed immediate challenges for dental care and education. Due to the need to establish infection prevention and control guidance in dental health settings to enable a safe clinical practice, this review aims to list the challenges and perspectives in managing dental care in services and schools. This review employed materials collected from PubMed and the main guidelines and studies on the novel coronavirus to provide an overview of the clinical procedures and decisions made by health care personnel in dental offices and dental schools. We expect the COVID-19 scenario to promote significant changes in clinical practice and dental education; dentists should seek specific and particular regulations for dental practice established by their state or country. Biosafety checklists are strongly recommended for appointments at dental services and face-to-face activities in dental schools

Avaliação óssea de regiões maxilares candidatas à reabilitação unitária implantossuportada: uma comunicação curta

Objective: Evaluate the height and bone thickness in healed sites of single implant areas. Materials and Methods: In this cross-sectional study, cone-beam computed tomography (CBCT) images of single edentulous areas of maxilla of patients who needed aesthetic single implant rehabilitations were evaluated for measure the height and thickness using an implant planning software. Data were statistically analyzed using the Mann-Whitney and Pearson correlation test, considering the time, reason and region of tooth loss. For all tests, a p-valueObjetivo: Avaliar a altura e espessura óssea em sítios unitários cicatrizados. Materiais e Métodos: Neste estudo transversal, imagens de tomografia computadorizada de feixe cônico (TCFC) de regiões edêntulas unitárias maxilares de pacientes candidatos a reabilitação unitária implantossuportada foram mensuradas em relação à altura e espessura óssea usando um software de planejamento de implante. Os dados foram analisados estatisticamente por meio do teste Mann-Whitney e de correlação de Pearson, considerando o tempo, o motivo e região da perda dentária. Para todos os testes, um valor de

Intensidade da dor e nível de depressão em pacientes com disfunção temporomandibular crônica

Aim: The aim of this study was to assess the correlation between pain intensity and the level of depression in patients with chronic temporomandibular disorders (TMD). Materials and methods: Fifty-five volunteers diagnosed by the Research Diagnostic Criteria (RDC/TMD) were assessed for pain intensity and level of depression. Pain intensity and level of depression were assessed using a visual analysis scale and Beck depression inventory, respectively. Data analysis was conducted using confidence intervals and Pearson’s chi-square test (p< 0.05). Results: The results demonstrated that non-depressed individuals (43.6%) showed a mean pain intensity of 28.27mm, those with mild depression (38.2%) 34.24mm, and those moderate depression (18.2%) 50.7mm. Statistical analysis showed that there was a positive and significant correlation between pain intensity and level of depression (p=0.004). Discussion: This study found a positive correlation between pain intensity and depression level in chronic TMD patients. However, it has not been elucidated yet how TMD are correlated to depression and in which way depression can influence its onset and perpetuation. Conclusion: The level of depression may play an important role in the intensity of chronic pain, therefore, a multidisciplinary intervention seems to be important for the treatment success.Objetivo: Este estudo objetivou avaliar a correlação entre a intensidade da dor e o nível de depressão em pacientes com disfunção temporomandibular (DTM) crônica. Materiais e métodos: Cinquenta e cinco voluntários diagnosticados pelos Critérios de diagnóstico para pesquisa das disfunções temporomandibulares (RDC / DTM) foram avaliados quanto à intensidade da dor e nível de depressão. A intensidade da dor e o nível de depressão foram avaliados por meio da escala analógica visual e do inventário de depressão de Beck, respectivamente. A análise dos dados foi realizada usando intervalos de confiança e teste do qui-quadrado de Pearson (

Erratum to: The study of cardiovascular risk in adolescents – ERICA: rationale, design and sample characteristics of a national survey examining cardiovascular risk factor profile in Brazilian adolescents

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