Canadian Wilderness

Non-fiction by Conrad Dee Brown

Hi - Ho The Merrio (As Long As She Loves Me)

With Ukulele arrangement. Contains advertisements and/or short musical examples of pieces being sold by publisher.https://digitalcommons.library.umaine.edu/mmb-vp/7082/thumbnail.jp

The sociology of pharmaceuticals: progress and prospects

This paper takes a critical look at progress and prospects regarding the sociology of pharmaceuticals over the years. Key themes examined include: (i) medicalisation and pharmaceuticalisation; (ii) regulation; (iii) consumption and consumerism; (iv) expectations and innovation. Papers in the monograph are also introduced and discussed in relation to these themes. The paper concludes with some further comments and reflections on progress and prospects in this field, emphasising the continuing importance of sociological engagement with these personal and political issues in the 21st century

Critical success factors to improve direct labour productivity

An increase in the global competitiveness has forced manufacturing organisations to re-look their facility from a labour productivity standpoint. Leveraging a manufacturing operation into a competitive avantage must at all times support the organisation’s objective. It is therefore critical that the operation reviews its strategy so that it fulfils the ever changing needs in the market. Purpose – The main objective of this research is to identify the critical success factors to improve direct labour efficiency within Johnson Controls Automotive South Africa (Pty) Ltd (JCI). Design/methodology/approach – A combination of a comprehensive literature review and visits to the Uitenhage plant and head office were employed in the study. JCI practices were observed to highlight the level of direct labour productivity. This was followed by interviewing relevant and key personel who had an involvement in achieving direct labour productivity in the plant. A questionnaire-based research approach was adopted for this purpose and a total of 83 valid survey responses were received from staff in the Uitenhage plant, together with head office staff who directly supported the plant. The questionnaire was designed to identify and test perceptions of employees, regarding the factors of production, identified as sub variables. The research aim was to determine the most practical and effective strategies to improve direct labour productivity. Results were analysed and interpreted after which recommendations were formulated. Findings – Several critical success factors identified as sub variables were tested to understand their impact on direct labour productivity. Empirical results showed that organisational culture, leadership culture, employee engagement, communication and skills, development and training, had a significant effect on direct labour productivity. Respective ratings of these elements were discussed with the focus of improving this going forward. Research limitations/implications – Continued scepticim within JCI about the benefits of direct labour productivity to their business is one of the fundamental limitations this research faces. Originality/value – The novelty of the research project stems from the realization of key factors contributing to the improvement of direct labour productivity within the JCI enviroment. The results would provide JCI with indicators and guidelines for a successful implementation of direct labour productivity initiatives in the Uitenhage plant

Cognitive psychology and survey methodology: nurturing the continuing dialogue between disciplines

No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/55949/1/1333_ftp.pd

Computational Study of Evolutionary Selection Pressure on Rainbow Trout Estrogen Receptors

Molecular dynamics simulations were used to determine the binding affinities between the hormone 17-estradiol (E2) and different estrogen receptor (ER) isoforms in the rainbow trout, Oncorhynchus mykiss. Previous phylogenetic analysis indicates that a whole genome duplication prior to the divergence of ray-finned fish led to two distinct ER isoforms, ER and ER, and the recent whole genome duplication in the ancestral salmonid created two ER isoforms, ER and ER. The objective of our computational studies is to provide insight into the underlying evolutionary pressures on these isoforms. For the ER subtype our results show that E2 binds preferentially to ER over ER. Tests of lineage specific N/S ratios indicate that the ligand binding domain of the ER gene is evolving under relaxed selection relative to all other ER genes. Comparison with the highly conserved DNA binding domain suggests that ER may be undergoing neofunctionalization possibly by binding to another ligand. By contrast, both ER and ER bind similarly to E2 and the best fitting model of selection indicates that the ligand binding domain of all ER genes are evolving under the same level of purifying selection, comparable to ER