Lower limb biomechanics and muscle function

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this recor

Sunshine Of Mine

https://digitalcommons.library.umaine.edu/mmb-vp/2982/thumbnail.jp

Exploring Work Satisfaction of Women in Educational Leadership from a Racial Perspective During Times of Crisis

In education, critical shifts and pandemic repercussions have heightened pressures. Women leaders, particularly those of color, grapple with gender and racial inequalities that shape their roles (Sanchez-Hucles & Davis, 2010). This study explores women\u27s leadership experiences, focusing on work satisfaction through a racial lens. Utilizing Resilience Theory, it delves into women\u27s perceptions, employing a quantitative approach through an electronic survey at a women educators\u27 conference. Examining racial categories, the research uncovers correlations between work satisfaction, job fit, commitment, and work-family balance. ANOVA results show no significant job satisfaction differences based on race, while Welch t-test identifies varied responses. Findings illuminate the intricate interplay of gender, race, and job satisfaction, shaped by cultural, social, and personal factors. These results, seen in the context of critical times in education, underscore the resilience of women in leadership roles. Acknowledging these dynamics, especially for women of color, enriches understanding for aspiring women leaders facing diverse educational leadership challenges

Student and Faculty Perceptions of the Impact of Masks on Student Learning and Communication in the Classroom

As a result of the COVID-19 pandemic, facemask requirements while indoors were implemented in colleges and universities, both in the United States and beyond. Empirical evidence has shown that such mandates improved the health and safety of students, faculty, staff, and administrators. However, the impacts of such precautions on student learning and communication have to date gone largely unexplored. The current study surveyed students and faculty at one regional midwestern institution to assess their perceptions on the impact of masks on student learning and communication in the classroom. Findings are included, followed by a discussion of their implications

Igniting Resilience During Critical Times: Reflections of Women Superintendents

This qualitative study sought to explore the perceptions of women school superintendents in K -12 public schools in Texas about the challenges they face as leaders and how they endure these impactful challenges, particularly during critical times such as the COVID-19 pandemic. Using Polidore’s Resilience Theory (2004) as the theoretical framework, the study sought to determine which of the nine resilience qualities, either innately possessed or through acquisition over time, helped to sustain the women superintendents during adverse situations associated with the highest level of leadership in a school district. The nine qualities of resilience include: religion, flexible locus of control, optimistic bias, autonomy, commitment, change, positive relationships, education viewed as important, and efficacy. Implications from this study are far-reaching and note-worthy for any position in educational leadership. The results from this study may positively enhance the experiences, retention, sustainability, effectiveness, and longevity of both women and men in one of the most important roles in a school district - the superintendency. Key words: resilience, women superintendents, women educational leaders, critical times, COVID-19 pandemic, Resilience Theor

Risk assessment for recrudescence of avian influenza in caged layer houses following depopulation : the effect of cleansing, disinfection and dismantling of equipment

Following an outbreak of highly pathogenic avian influenza virus (HPAIV) in a poultry house, control measures are put in place to prevent further spread. An essential part of the control measures based on the European Commission Avian Influenza Directive 2005/94/EC is the cleansing and disinfection (C&D) of infected premises. Cleansing and disinfection includes both preliminary and secondary C&D, and the dismantling of complex equipment during secondary C&D is also required, which is costly to the owner and also delays the secondary cleansing process, hence increasing the risk for onward spread. In this study, a quantitative risk assessment is presented to assess the risk of re-infection (recrudescence) occurring in an enriched colony-caged layer poultry house on restocking with chickens after different C&D scenarios. The risk is expressed as the number of restocked poultry houses expected before recrudescence occurs. Three C&D scenarios were considered, namely (i) preliminary C&D alone, (ii) preliminary C&D plus secondary C&D without dismantling and (iii) preliminary C&D plus secondary C&D with dismantling. The source-pathway-receptor framework was used to construct the model, and parameterisation was based on the three C&D scenarios. Two key operational variables in the model are (i) the time between depopulation of infected birds and restocking with new birds (TbDR) and (ii) the proportion of infected material that bypasses C&D, enabling virus to survive the process. Probability distributions were used to describe these two parameters for which there was recognised variability between premises in TbDR or uncertainty due to lack of information in the fraction of bypass. The risk assessment estimates that the median (95% credible intervals) number of repopulated poultry houses before recrudescence are 1.2 × 104 (50 to 2.8 × 106), 1.9 × 105 (780 to 5.7 × 107) and 1.1 × 106 (4.2 × 103 to 2.9 × 108) under C&D scenarios (i), (ii) and (iii), respectively. Thus for HPAIV in caged layers, undertaking secondary C&D without dismantling reduces the risk by 16-fold compared to preliminary C&D alone. Dismantling has an additional, although smaller, impact, reducing the risk by a further 6-fold and thus around 90-fold compared to preliminary C&D alone. On the basis of the 95% credible intervals, the model demonstrates the importance of secondary C&D (with or without dismantling) over preliminary C&D alone. However, the extra protection afforded by dismantling may not be cost beneficial in the context of reduced risk of onward spread

CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping, fatal neurodegenerative disorders in which the molecular and pathogenic basis remains poorly understood. Ubiquitinated protein aggregates, of which TDP-43 is a major component, are a characteristic pathological feature of most ALS and FTD patients. Here we use genome-wide linkage analysis in a large ALS/FTD kindred to identify a novel disease locus on chromosome 16p13.3. Whole-exome sequencing identified a CCNF missense mutation at this locus. Interrogation of international cohorts identified additional novel CCNF variants in familial and sporadic ALS and FTD. Enrichment of rare protein-altering CCNF variants was evident in a large sporadic ALS replication cohort. CCNF encodes cyclin F, a component of an E3 ubiquitin-protein ligase complex (SCF(Cyclin F)). Expression of mutant CCNF in neuronal cells caused abnormal ubiquitination and accumulation of ubiquitinated proteins, including TDP-43 and a SCF(Cyclin F) substrate. This implicates common mechanisms, linked to protein homeostasis, underlying neuronal degeneration