377 research outputs found
On the Self-Affine Roughness of a Crack Front in Heterogeneous Media
The long-ranged elastic model, which is believed to describe the evolution of
a self-affine rough crack-front, is analyzed to linear and non-linear orders.
It is shown that the nonlinear terms, while important in changing the front
dynamics, are not changing the scaling exponent which characterizes the
roughness of the front. The scaling exponent thus predicted by the model is
much smaller than the one observed experimentally. The inevitable conclusion is
that the gap between the results of experiments and the model that is supposed
to describe them is too large, and some new physics has to be invoked for
another model.Comment: 4 pages, 4 figure
A <i>cis</i>-regulatory sequence acts as a repressor in the <i>Arabidopsis thaliana</i> sporophyte, but as an activator in pollen
A generalization of the Bombieri-Pila determinant method
The so-called determinant method was developed by Bombieri and Pila in 1989
for counting integral points of bounded height on affine plane curves. In this
paper we give a generalization of that method to varieties of higher dimension,
yielding a proof of Heath-Brown's 'Theorem 14' by real-analytic considerations
alone.Comment: 13 page
High-throughput calculations of charged point defect properties with semi-local density functional theory—performance benchmarks for materials screening applications
Calculations of point defect energetics with Density Functional Theory (DFT) can provide valuable insight into several optoelectronic, thermodynamic, and kinetic properties. These calculations commonly use methods ranging from semi-local functionals with a-posteriori corrections to more computationally intensive hybrid functional approaches. For applications of DFT-based high-throughput computation for data-driven materials discovery, point defect properties are of interest, yet are currently excluded from available materials databases. This work presents a benchmark analysis of automated, semi-local point defect calculations with a-posteriori corrections, compared to 245 “gold standard” hybrid calculations previously published. We consider three different a-posteriori correction sets implemented in an automated workflow, and evaluate the qualitative and quantitative differences among four different categories of defect information: thermodynamic transition levels, formation energies, Fermi levels, and dopability limits. We highlight qualitative information that can be extracted from high-throughput calculations based on semi-local DFT methods, while also demonstrating the limits of quantitative accuracy
Theory of dynamic crack branching in brittle materials
The problem of dynamic symmetric branching of an initial single brittle crack
propagating at a given speed under plane loading conditions is studied within a
continuum mechanics approach. Griffith's energy criterion and the principle of
local symmetry are used to determine the cracks paths. The bifurcation is
predicted at a given critical speed and at a specific branching angle: both
correlated very well with experiments. The curvature of the subsequent branches
is also studied: the sign of , with being the non singular stress at the
initial crack tip, separates branches paths that diverge from or converge to
the initial path, a feature that may be tested in future experiments. The model
rests on a scenario of crack branching with some reasonable assumptions based
on general considerations and in exact dynamic results for anti-plane
branching. It is argued that it is possible to use a static analysis of the
crack bifurcation for plane loading as a good approximation to the dynamical
case. The results are interesting since they explain within a continuum
mechanics approach the main features of the branching instabilities of fast
cracks in brittle materials, i.e. critical speeds, branching angle and the
geometry of subsequent branches paths.Comment: 41 pages, 15 figures. Accepted to International Journal of Fractur
Recent ecological change in ancient lakes
Ancient lakes are among the best archivists of past environmental change, having experienced more than one full glacial cycle, a wide range of climatic conditions, tectonic events, and long association with human settlements. These lakes not only record long histories of environmental variation and human activity in their sediments, but also harbor very high levels of biodiversity and endemism. Yet, ancient lakes are faced with a familiar suite of anthropogenic threats, which may degrade the unusual properties that make them especially valuable to science and society. In all ancient lakes for which data exist, significant warming of surface waters has occurred, with a broad range of consequences. Eutrophication threatens both native species assemblages and regional economies reliant on clean surface water, fisheries, and tourism. Where sewage contributes nutrients and heavy metals, one can anticipate the occurrence of less understood emerging contaminants, such as pharmaceuticals, personal care products, and microplastics that negatively affect lake biota and water quality. Human populations continue to increase in most of the ancient lakes’ watersheds, which will exacerbate these concerns. Further, human alterations of hydrology, including those produced through climate change, have altered lake levels. Co‐occurring with these impacts have been intentional and unintentional species introductions, altering biodiversity. Given that the distinctive character of each ancient lake is strongly linked to age, there may be few options to remediate losses of species or other ecosystem damage associated with modern ecological change, heightening the imperative for understanding these systems
Long-term outcome of displaced radial neck fractures in adulthood: 16–21 year follow-up of 5 patients treated with radial head excision
Background There have been no reports on the long-term outcome of radial neck Mason type IIIb fractures in adults
Recommendations for respiratory syncytial virus surveillance at national level
Respiratory syncytial virus (RSV) is a common cause of acute lower respiratory tract infections and hospitalisations among young children and is globally responsible for many deaths in young children, especially in infants aged <6 months. Furthermore, RSV is a common cause of severe respiratory disease and hospitalisation among older adults. The development of new candidate vaccines and monoclonal antibodies highlights the need for reliable surveillance of RSV. In the European Union (EU), no up-to-date general recommendations on RSV surveillance are currently available. Based on outcomes of a workshop with 29 European experts in the field of RSV virology, epidemiology and public health, we provide recommendations for developing a feasible and sustainable national surveillance strategy for RSV that will enable harmonisation and data comparison at the European level. We discuss three surveillance components: active sentinel community surveillance, active sentinel hospital surveillance and passive laboratory surveillance, using the EU acute respiratory infection and World Health Organization (WHO) extended severe acute respiratory infection case definitions. Furthermore, we recommend the use of quantitative reverse transcriptase PCR-based assays as the standard detection method for RSV and virus genetic characterisation, if possible, to monitor genetic evolution. These guidelines provide a basis for good quality, feasible and affordable surveillance of RSV. Harmonisation of surveillance standards at the European and global level will contribute to the wider availability of national level RSV surveillance data for regional and global analysis, and for estimation of RSV burden and the impact of future immunisation programmes
Thermal fracture as a framework for quasi-static crack propagation
We address analytically and numerically the problem of crack path prediction
in the model system of a crack propagating under thermal loading. We show that
one can explain the instability from a straight to a wavy crack propagation by
using only the principle of local symmetry and the Griffith criterion. We then
argue that the calculations of the stress intensity factors can be combined
with the standard crack propagation criteria to obtain the evolution equation
for the crack tip within any loading configuration. The theoretical results of
the thermal crack problem agree with the numerical simulations we performed
using a phase field model. Moreover, it turns out that the phase-field model
allows to clarify the nature of the transition between straight and oscillatory
cracks which is shown to be supercritical.Comment: 19 pages, 8 figure
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