Rebelling with Care.:Exploring open technologies for commoning healthcare

The publication Rebelling with Care is the result of the research and dissemination activities carried out by WeMake within the framework of DSI for Europe, a project supported by the European Commission to reinforce the network of organizations using technologies to make a positive impact on society. The DSI paradigm revolves around key concepts such as open codes and data, co-design, collaboration and social impact. Since January 2018, we have reflected upon the traction these terms could have specifically in the field of health and care practices, starting with a map of the current DSI ecosystem and an informal learning journey that has involved citizens, policy-makers, professionals and institutions. What does it mean to develop bottom-up innovation, which is community-driven and built upon the commons, in a sector that is struggling to meet the needs of a growing and aging society, that is ruled by obsolete bureaucracies, and that is limited by proprietary technologies and top-down procedures? We have tried to answer these questions through seven articles and seven practices that show in concrete terms the contours of the emerging and diverse new modalities of dealing with the health and care challenges of today by leveraging the empowering potential of digital technologies. In the context of this research, we came to define these different modalities, which often emerge from the strong personal needs of the people directly impacted by a specific condition, as “rebel practices”. This is because in the vast majority of cases, these practices simultaneously operate outside a market logic without asking for the full permission of official institutions, with the purpose of provoking them to change or filling the gap left by who do not innovate, with due care, in the fields of health and care provisions

Cure Ribelli. Tecnologie aperte per una cura come bene comune

Cure Ribelli è una pubblicazione che nasce dalle attività di ricerca e disseminazione svolte da WeMake nell’ambito del progetto Digital Social Innovation for Europe, un programma supportato dalla Commissione Europea che punta a rafforzare la rete di organizzazioni che propongono l’utilizzo delle tecnologie con una prospettiva mirata all’impatto positivo sulla società. I concetti chiave del paradigma dell’innovazione sociale digitale gravitano intorno a termini quali codici e dati aperti, co-progettazione, collaborazione, impatto sociale. Dal gennaio 2018 abbiamo riflettuto e ci siamo confrontate sulla declinazione di tali concetti nell’ambito della cura e della salute a partire da una mappatura del contesto e da un percorso formativo informale che ha coinvolto cittadini, referenti politici, professionisti e istituzioni. Che cosa significa sviluppare un’innovazione dal basso guidata dalla comunità e fondata sui beni comuni, in un settore impreparato al crescente invecchiamento della popolazione, governata da burocrazie obsolete, e che è limitata da tecnologie proprietarie e procedure verticistiche? Abbiamo cercato di rispondere a queste domande attraverso sette articoli e sette pratiche progettuali che danno concretamente forma ad altri e nuovi modi di fare cura e occuparsi della salute sfruttando il potenziale emancipatorio delle tecnologie digitali. Nell’ambito di questa ricerca, abbiamo voluto definire questi altri modi “ribelli” poiché spesso nascono da forti esigenze personali delle persone direttamente interessate che, nella maggior parte dei casi, agiscono senza chiedere il permesso di mercati e istituzioni, per provocarli al fine di farli cambiare o per sopperire alle carenze di chi dovrebbe ma non innova, con cura, il settore della salute

Managing the commons in the knowledge economy

The work leading to this publication has received funding from the European Union’s Seventh Framework Programme (FP7/2007- 2013) under grant agreement n° 610349.This report presents an in-depth analysis of the concept of common goods and of possible political and management variation in the context of a knowledge-based economy. The research presents an initial critical review of the literature together with a concrete analysis of the development of the commons and common goods.The report will be organised in three sections. In the first, entitled "From the theory of public goods to the new political economy of the commons" we will see how, for Ostrom's new theory of the commons, what remains as a central element defining common goods is the particular nature of certain goods, in continuity with the ahistorical and static approach to classification of goods (private, public, common, belonging to a club) driven by neo-classical inspired economic theory.In the second section we will develop the approach of Common in the singular drawn up with the contribution of numerous studies in the theoretical framework of cognitive capitalism.The third will deal with the historic and empirical analysis of the origin, sense and principal stakes at play in the dynamics of the common, starting from the key role of the transformations of labour at the foundation of a knowledge-based economy.Throughout this journey, in the three sections different crucial aspects relating to the forms of regulation open to guarantee the sustainability of the commons and promote its development as a new central form of economic and social organisation will be faced systematically.This research offers an exhaustive theoretical framework, tackling all the conceptual and historical issues on the evolution of the theory of common goods. At the same time however, it offers practical and regulative examples of models of self-governance of commons, in the context of the knowledge-based economy. This analysis offers the D-CENT project possible models of democratic management of resources and common infrastructures that are at the base of the experience of shared democracy in Spain, Iceland and Finland, with the aim of achieving middle and long-term sustainability. Specifically speaking, the analysis submitted here reports: (1) research into the market of identity and the opposing claim of social data as digital common goods and the need for public and common infrastructures of information and communication not based on the logic of the market and surveillance (D3.3); (2) models to implement a commons currency of the common that can support the activities of social movements and productive communities (D3.5); (3) the final report (D1.3) on models of sustainability and the general impact of this project.Many of the examples proposed here, from the re-municipalisation of water, the self-management of cultural spaces to the free software and makers’ movement, illustrate collective practices that establish new spaces, institutions or norms of participative and democratic sharing. These examples represent practices of re-appropriation and management of the common, new practices of labour, creation and production based on collaboration and sharing.Moreover, from the concrete experiences analysed here, the idea emerges that the concept of common goods can constitute a concrete alternative, and that includes on a legal footing (Rodotà, 2011). Therefore the common is the product of a social and institutional structure that demonstrates forms of governing and social co-operation that guarantee its production, reproduction and spread. The new institutions of the common that emerge from these constituent practices constitute a general principle of self-governance of society and self-organisation of socialproduction, proposing a new division between common, public and private.Obviously, the success of these new practices is a complex process that must rely on institutions which accord and guarantee reproduction over time and space of the commons and common goods: ways of management based on self-governance and collaborative economics; relationships of exchange based on reciprocity and gratuitousness; legal regimes that, like the invention of copyleft for free software, guarantee the accumulation of a stock of common-pool resources (CPR); distribution norms that permit the active involvement of the commoners in the development of the commons, guaranteeing a basic income, for example.In this context, it becomes more and more essential and urgent to define the terms of an alternative model of regulating a knowledge-based society and economy at the centre of which the logic of the commons would perform an essential role

Cure Ribelli. Tecnologie aperte per una cura come bene comune.

Cure Ribelli è una pubblicazione che nasce dalle attività di ricerca e disseminazione svolte da WeMake nell’ambito del progetto Digital Social Innovation for Europe, un programma supportato dalla Commissione Europea che punta a rafforzare la rete di organizzazioni che propongono l’utilizzo delle tecnologie con una prospettiva mirata all’impatto positivo sulla società. I concetti chiave del paradigma dell’innovazione sociale digitale gravitano intorno a termini quali codici e dati aperti, co-progettazione, collaborazione, impatto sociale. Dal gennaio 2018 abbiamo riflettuto e ci siamo confrontate sulla declinazione di tali concetti nell’ambito della cura e della salute a partire da una mappatura del contesto e da un percorso formativo informale che ha coinvolto cittadini, referenti politici, professionisti e istituzioni. Che cosa significa sviluppare un’innovazione dal basso guidata dalla comunità e fondata sui beni comuni, in un settore impreparato al crescente invecchiamento della popolazione, governata da burocrazie obsolete, e che è limitata da tecnologie proprietarie e procedure verticistiche? Abbiamo cercato di rispondere a queste domande attraverso sette articoli e sette pratiche progettuali che danno concretamente forma ad altri e nuovi modi di fare cura e occuparsi della salute sfruttando il potenziale emancipatorio delle tecnologie digitali. Nell’ambito di questa ricerca, abbiamo voluto definire questi altri modi “ribelli” poiché spesso nascono da forti esigenze personali delle persone direttamente interessate che, nella maggior parte dei casi, agiscono senza chiedere il permesso di mercati e istituzioni, per provocarli al fine di farli cambiare o per sopperire alle carenze di chi dovrebbe ma non innova, con cura, il settore della salute

Poor efficacy of palbociclib in second-line treatment of metastatic lobular breast cancer in a case series: Use before or never more?

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Pla Digital de l'Ajuntament de Barcelona

A la coberta: Programa de digitalització oberta del Comissionat/da de Tecnologia i Innovació Digital de l'Ajuntament de Barcelona

Crizotinib in MET-Deregulated or ROS1-Rearranged Pretreated Non-Small Cell Lung Cancer (METROS): A Phase II, Prospective, Multicenter, Two-Arms Trial.

PURPOSE: MET-deregulated NSCLC represents an urgent clinical need because of unfavorable prognosis and lack of specific therapies. Although recent studies have suggested a potential role for crizotinib in patients harboring MET amplification or exon 14 mutations, no conclusive data are currently available. This study aimed at investigating activity of crizotinib in patients harboring MET or ROS1 alterations. PATIENTS AND METHODS: Patients with pretreated advanced NSCLC and evidence of ROS1 rearrangements (cohort A) or MET deregulation (amplification, ratio MET/CEP7 >2.2 or MET exon 14 mutations, cohort B) were treated with crizotinib 250 mg twice daily orally. The coprimary endpoint was objective response rate in the two cohorts. RESULTS: From December 2014 to March 2017, 505 patients were screened and a total of 52 patients (26 patients per cohort) were enrolled onto the study. At data cutoff of September 2017, in cohort A, objective response rate was 65%, and median progression-free survival and overall survival were 22.8 months [95% confidence interval (CI) 15.2-30.3] and not reached, respectively. In cohort B, objective response rate was 27%, median progression-free survival was 4.4 months (95% CI 3.0-5.8), and overall survival was 5.4 months (95% CI, 4.2-6.5). No difference in any clinical endpoint was observed between MET-amplified and exon 14-mutated patients. No response was observed among the 5 patients with cooccurrence of a second gene alteration. No unexpected toxicity was observed in both cohorts. CONCLUSIONS: Crizotinib induces response in a fraction of MET-deregulated NSCLC. Additional studies and innovative therapies are urgently needed

Innovative public procurement guide

Podeu consultar la versió en català a: http://hdl.handle.net/11703/113907Podeu consultar la versió en castellà a: http://hdl.handle.net/11703/11563

Barcelona City Council ICT Public Procurement Guide

Les mencions de responsabilitat s'han basat en els crèdits facilitats per l'àrea responsablePodeu consultar la versió en català a: http://hdl.handle.net/11703/106505Podeu consultar la versió en castellà a: http://hdl.handle.net/11703/115663Directrius per a definir el nou model de relació amb els proveïdors de tecnologia basat en el Codi de Pràctiques Tecnològique