606 research outputs found
Sexually-transmitted disease risk in a Micronesian atoll population
The potential health threat of AIDS to the native island-based populations in the Pacific is now widely appreciated by those working in the public-health sector throughout the region. Although several countries in the region are yet to identify any cases of AIDS or HIV seropositivity, there is reason to suspect that heterosexual contact may emerge as a predominant mode of spread of HIV infection into native Pacific island populations. Sexual networks and their relationship to potentially ârisky behavioursâ are described for a single native Micronesian atoll community on the basis of ethnographic observation and interviewing. This description is combined with the investigation of historic-demographic dimensions of the epidemiology of sexually-transmitted diseases in the same population to draw some conclusions about the opportunities for HIV transmission and acquisition among the sexually-active portions of this community. Although sexually-transmitted diseases have not had an appreciable epidemiological or demographic impact on the population in the past, the sexual networks within the community and beyond provide ample opportunity for the introduction and spread of sexually transmitted diseases, including HIV and its sequel AIDS
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Developing workplace menopause policies: four reasons why, and how
Menopause is increasingly â if finally â being acknowledged as an important workplace issue. Five experts from different fields discuss the social, business, legal and ethical cases for improving support at work for women transitioning through the menopause, and explain how to start and sustain the conversation with employers.
Menopause â when a woman stops having periods for good â is currently receiving an increasing amount of attention. Celebrities including Kirsty Wark, Davina McCall, Gillian Anderson, Jenny Eclair, Meg Mathews, Carol Vorderman and Cynthia Nixon have shared their experiences of this natural, and yet often taboo, mid-life transition with the wider world. Also noticeable is a groundswell among employers across a variety of sectors that are acknowledging the significant effects menopause symptoms
Activation of the glycosyl-phosphatidylinositol-anchored membrane dipeptidase upon release from pig kidney membranes by phospholipase C
Incubation of pig kidney microvillar membranes with Bacillus thuringiensis or Staphylococcus aureus phosphatidylinositol-specific phospholipase C (PI-PLC) resulted in the release of a number of glycosyl-phosphatidylinositol (GPI)-anchored hydrolases, including alkaline phosphatase (EC 3.1.3.1), amino-peptidase P (EC 3.4.11.9), membrane dipeptidase (EC 3.4.13.19), 5'-nucleotidase (EC 3.1.3.5) and trehalase (EC 3.2.1.28). Of these five ectoenzymes only for membrane dipeptidase was there a significant (approx. 100%) increase in enzymic activity upon release from the membrane. Maximal activation occurred at a PI-PLC concentration 10-fold less than that required for maximal release. In contrast solubilization of the membranes with n-octyl beta-D-glucopyranoside had no effect on the enzymic activity of membrane dipeptidase. A competitive e.l.i.s.a. with a polyclonal antiserum to membrane dipeptidase indicated that the increase in enzymic activity was not due to an increase in the amount of membrane dipeptidase protein. Although PI-PLC cleaved the GPI anchor of the affinity-purified amphipathic form of pig membrane dipeptidase there was no concurrent increase in enzymic activity. In the absence of PI-PLC, membrane dipeptidase in the microvillar membranes hydrolysed Gly-D-Phe with a Km of 0.77 mM and a Vmax. of 602 nmol/min per mg of protein. However, in the presence of a concentration of PI-PLC which caused maximal release from the membrane and maximal activation of membrane dipeptidase the Km was decreased to 0.07 mM while the Vmax. remained essentially unchanged at 624 nmol/min per mg of protein. Overall these results suggest that cleavage by PI-PLC of the GPI anchor on membrane dipeptidase may relax conformational constraints on the active site of the enzyme which exist when it is anchored in the lipid bilayer, thus resulting in an increase in the affinity of the active site for substrate
Dangerous work: The gendered nature of bullying in the context of higher education
This paper discusses results from a research project which set out to investigate gender differences in the nature and experience of bullying within the higher education sector. Gender differences emerged in the form and perception of bullying as well as in target response. Results also indicate that, irrespective of gender, bullies can capture and subvert organizational structures and procedures (official hierarchies, mentoring systems, probationary reviews) to further their abuse of the target and to conceal aggressive intent. These outcomes are discussed in relation to gendered assumptions behind management practices and in relation to the masculinist ethic that underpins many higher education management initiatives. Overall, results indicate that bullying cannot be divorced from gender and that such behaviour needs to be seen in a gendered context
Maternal Perception of Child Weight Among Mexicans in California and Mexico
The prevalence of childhood overweight is high in Mexican immigrant communities in the United States. Understanding motherâs perceptions of child weight in immigrantsâ country of origin may help to understand this high prevalence. The goal of this study was to examine and compare mothersâ perception of weight in Mexico (MX) and in an immigrant community in California (CA). We assessed perceptions of child weight using a pictorial scale with 314 mothers of 5-year-old children in MX and 60 mothers of 5Â year-old-children in CA. We compared maternal reports with childrenâs objectively measured weight. Using chi-square and Analysis of Variance, we investigated associations of maternal perception of and satisfaction with weight according to socio-demographic characteristics. Mothers were more likely to underestimate their childrenâs weight in CA than in MX. On average, CA mothers wanted their children to be smaller than they currently were and mothers in MX wanted their children to be bigger than they currently were. This differed by weight status in CA with mothers of normal weight and at-risk-for-overweight children wanting them to be bigger and mothers of overweight children wanting them to be smaller. In order for programs to be effective, mothers must be able to recognize their children as overweight and want to address it. Because underestimation of weight and a desire for a larger size is common in this population, programs to address overweight may be more effective if they focus on alternative benefits of weight control strategies, such as healthy child development
Womenâs experiences of menopause at work and performance management
Presenting findings from our global evidence review of menopause transition and economic participation emboldened us to establish a menopause policy at the university where we all worked at the time. Our report was published in July 2017 and the policy was in place by November that year. Our critical reflection on this activism focuses on issues that are not commonly recognized around such interventions, and which we ourselves have only been able to acknowledge through engaged action. Challenges remain in normalizing menopause in organizations, specifically around gendered ageism and performance management. In drawing on Meyerson and Kolbâs framework for understanding gender in organizations, we highlight how policies are both vital and yet insufficient in and of themselves in revising the dominant discourse around menopause at work. At the same time, we highlight the importance and shortcomings of academic activism within these processes
On our own terms : the working conditions of internet-based sex workers in the UK
The sex industry is increasingly operated through online technologies, whether this is selling services online through webcam or advertising, marketing or organising sex work through the Internet and digital technologies. Using data from a survey of 240 internet-based sex workers (members of the National Ugly Mug reporting scheme in the UK), we discuss the working conditions of this type of work. We look at the basic working patterns, trajectories and everyday experiences of doing sex work via an online medium and the impact this has on the lives of sex workers. For instance, we look at levels of control individuals have over their working conditions, prices, clientele and services sold, and discuss how this is mediated online and placed in relation to job satisfaction. The second key finding is the experience of different forms of crimes individuals are exposed to such as harassment and blackmail via the new technologies. We explore the relationship internet-based sex workers have with the police and discuss how current laws in the UK have detrimental effects in terms of safety and access to justice. These findings are placed in the context of the changing landscape of sex markets as the digital turn determines the nature of the majority of commercial sex encounters. These findings contribute significantly to the populist coercion/choice political debates by demonstrating levels and types of agency and autonomy experienced by some sex workers despite working in a criminalized, precarious and sometimes dangerous context
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