Four temptations against urban renewel: an approach to fur current urban processes

Comunicación presentada en 25 European Network housing Research International Conference. Tarragona 19 al 22 junio 2013The new paradigm of urban social and economic rehabilitation is replacing the current sprawl growth model. But four temptations must be considered: 1) The high-density. This process is possible in sprawl model, but its quantification does not seem to be clear, because after a certain threshold of occupancy per unit area, the city seems to collapse and social and environmental benefits disappear, appearing reversal processes city to country in search of a minimum quality of life standards. There is not a model for appropriate density. It depends on the way of life of population, the traditional city model. 2) The replacement. Architectonic and urban rehabilitation must be preferred to replacement, except for certain cases to be legally taxed. But as the city cannot be densified and orderly, without the prior replacement of the building, may fit this temptation. Even replacing the building can be made without considering high building standards 3) The gentrification. There is a wide doctrine and experience about this phenomenon with serious social consequences. It is very tempting to replace the building, due to improve requirement of broad levels of quality, entering a game of speculation, so common in our real estate market. 4) The eco-city. Comprehensive projects are building spaces with low levels of energy consumption. Fall into this temptation means to continue the extensive city model we have been developing, creating new cities far from the existing but incorporating saving measures, and continuing resource consumptio

Linear-analog transformation approach for coupled gas and power flow analysis

In this paper, we present a methodology to analyze the integrated operation of coupled natural gas and electricity networks in steady-state. The interaction of the gas network with the electrical grid is modeled through mathematical equations that represent the energy exchange between the two infrastructures. The joint natural gas and power flow is solved using the linear-analog transformation (LAT) and the Newton-Raphson (NR) algorithm, respectively. Here, a unified solution framework of the two systems is presented using the previous proposed methods. The applicability of the methodology is illustrated using two case studies: IEEE-14 bus test system combined with a 16-node natural gas network and the IEEE-30 bus test system integrated with a 15-node natural gas network with 4 compressors. The proposed methodology proves to be useful for the assessment of coupled natural gas and electricity critical infrastructures

Inoculation site from a cutaneous melanoma patient treated with an allogeneic therapeutic vaccine: A case report

We have developed a therapeutic vaccine consisting of a mixture of lethally-irradiated allogeneic cutaneous melanoma cell lines with BCG and GM-CSF as adjuvants. The CSF-470 vaccine is currently being assayed in a Phase II-III trial against medium-dose IFN-a2b. All vaccinated patients immunized intradermally developed large edematous erythema reactions, which then transformed into subcutaneous nodules active for several months. However, vaccine injection sites were not routinely biopsied. We describe the case of a female patient, previously classified as stage III, but who, due to the simultaneous discovery of bone metastases only received one vaccination was withdrawn from the study, and continued her treatment elsewhere. This patient developed a post-vaccination nodule which was surgically removed 7 weeks later, and allowed to analyze the reactivity and immune profiling of the inoculation site. An inflammatory reaction with zones of fibrosis, high irrigation, and brisk lymphoid infiltration, primarily composed of CD8+ and CD20+ lymphocytes, was observed. There were no remaining BCG bacilli, and scarce CD4+ and Foxp3+ T cells were determined. MART-1 Ag was found throughout the vaccination site. CD11c+ Ag presenting cells were either dispersed or forming dense nests. Some CD11c+ cells proliferated; most of them contained intracellular MART-1 Ag, and some interacted with CD8+ lymphocytes. These observations suggest a potent, long-lasting local inflammatory response with recruitment of Ag-presenting cells that incorporate melanoma Ags, probably leading to Ag presentation to naïve T cells.Fil: Aris, Mariana. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Bravo, Alicia Ines. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Barrio, Maria Marcela. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mordoh, Jose. Fundación Instituto Leloir; Argentina. Fundación Cáncer. Centro de Investigaciones Oncológicas; Argentina. Instituto Alexander Fleming.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Identificacion de los factores epigeneticos determinantes de un envejecimiento cerebral saludable y patologico

102 p.El envejecimiento corresponde a un proceso normal, universal, gradual, multidimensional e irreversible en las distintas especies, incluida la humana, que lleva finalmente a la muerte. La senescencia genera cambios biopsicosociales en los individuos, y en ocasiones se asocia a una alta prevalencia de enfermedades crónicas invalidantes (enfermedad de Alzheimer-EA- y Parkinson-EP) y es por ello que el envejecimiento poblacional que se vive en muchos países, incluido Chile, despierta un alto interés social, económico y político. Por lo tanto, y conocido que Chile es un país con un mayor número de población envejecida, probablemente invalidante funcionalmente y cognitivamente, es que pretendemos ser una fuente de información sistemática y confiable, que apoye y fundamente el quehacer kinésico. Enfocando la atención en el respaldo bibliográfico que rechaza el considerar al proceso de envejecimiento normal como un evento patológico. Como objetivo se pretende identificar los factores epigenéticos determinantes de un envejecimiento cerebral saludable y patológico. Y para dar respuesta a éste se realiza una revisión bibliográfica de publicaciones entre el año 1994-2007 en revistas científicas como ISI Web of de Science, Scielo, PubMed y Cochrane, y bases de datos online y revistas disponibles en la Universidad de Talca y Pontificia Universidad Católica de Chile (PUC)

Enhanced numerical method for the design of 3D-printed holographic acoustic lenses for aberration correction of single-element transcranial focused ultrasound

[EN] The correction of transcranial focused ultrasound aberrations is a relevant issue for enhancing various non-invasive medical treatments. The emission through multi-element phased arrays has been the most widely accepted method to improve focusing in recent years; however, the number and size of transducers represent a bottleneck that limits the focusing accuracy of the technique. To overcome this limitation, a new disruptive technology, based on 3-D-printed acoustic lenses, has recently been proposed. As the submillimeter precision of the latest generation of 3-D printers has been proven to overcome the spatial limitations of phased arrays, a new challenge is to improve the accuracy of the numerical simulations required to design this type of ultrasound lens. In the study described here, we evaluated two improvements in the numerical model applied in previous works for the design of 3-D-printed lenses: (i) allowing the propagation of shear waves in the skull by means of its simulation as an isotropic solid and (ii) introduction of absorption into the set of equations that describes the dynamics of the wave in both fluid and solid media. The results obtained in the numerical simulations are evidence that the inclusion of both s-waves and absorption significantly improves focusing.This work was partially supported by the Spanish Ministerio de Economia y Empresa under Project TEC2015-68076-R. The authors thank Jose Sepulveda, director of Asociacion I2 CV, for his important input and scientific support.Ferri García, M.; Bravo, JM.; Redondo, J.; Sánchez Pérez, JV. (2019). Enhanced numerical method for the design of 3D-printed holographic acoustic lenses for aberration correction of single-element transcranial focused ultrasound. Ultrasound in Medicine & Biology. 45(3):867-884. https://doi.org/10.1016/j.ultrasmedbio.2018.10.022S86788445

Estimation of the Precision of a Structured Light System in Oil Paintings on Canvas

[EN] The conservation and authentication of pictorial artworks is considered an important part of the preservation of cultural heritage. The use of non-destructive testing allows the obtention of accurate information about the state of pictorial artworks without direct contact between the equipment used and the sample. In particular, the use of this kind of technology is recommended in obtaining three-dimensional surface digital models, as it provides high-resolution information that constitutes a kind of fingerprint of the samples. In the case of pictorial artworks with some kind of surface relief, one of the most useful technologies is structured light (SL). In this paper, the minimum difference in height that can be distinguished with this technology was estimated, establishing experimentally both the error committed in the measurement process and the precision in the use of this technology. This study focused on the case of oil paintings on canvas and developed a low-cost system to ensure its wide use.Sánchez-Jiménez, D.; Buchón Moragues, FF.; Bravo, JM.; Sánchez Pérez, JV. (2019). Estimation of the Precision of a Structured Light System in Oil Paintings on Canvas. Sensors. 19(22):1-13. https://doi.org/10.3390/s19224966S1131922Abate, D., Menna, F., Remondino, F., & Gattari, M. G. (2014). 3D painting documentation: evaluation of conservation conditions with 3D imaging and ranging techniques. The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, XL-5, 1-8. doi:10.5194/isprsarchives-xl-5-1-2014Pelagotti, A., Uccheddu, F., Massa, E., & Carfagni, M. (2018). Comparing two 3D measurement techniques for documenting painted wooden panels surface deformations on a real test case: «Mystical Marriage of Saint Catherine» by Renaissance artist Piero di Cosimo. IOP Conference Series: Materials Science and Engineering, 364, 012090. doi:10.1088/1757-899x/364/1/012090Ambrosini, D., Daffara, C., Di Biase, R., Paoletti, D., Pezzati, L., Bellucci, R., & Bettini, F. (2010). Integrated reflectography and thermography for wooden paintings diagnostics. Journal of Cultural Heritage, 11(2), 196-204. doi:10.1016/j.culher.2009.05.001Legrand, S., Vanmeert, F., Van der Snickt, G., Alfeld, M., De Nolf, W., Dik, J., & Janssens, K. (2014). Examination of historical paintings by state-of-the-art hyperspectral imaging methods: from scanning infra-red spectroscopy to computed X-ray laminography. Heritage Science, 2(1). doi:10.1186/2050-7445-2-13Bravo, J., Sánchez-Pérez, J., Ferri, M., Redondo, J., & Picó, R. (2014). Application of Ultrasound Phase-Shift Analysis to Authenticate Wooden Panel Paintings. Sensors, 14(5), 7992-8002. doi:10.3390/s140507992Remondino, F., Rizzi, A., Barazzetti, L., Scaioni, M., Fassi, F., Brumana, R., & Pelagotti, A. (2011). Review of Geometric and Radiometric Analyses of Paintings. The Photogrammetric Record, 26(136), 439-461. doi:10.1111/j.1477-9730.2011.00664.xBuchón-Moragues, F., Bravo, J., Ferri, M., Redondo, J., & Sánchez-Pérez, J. (2016). Application of Structured Light System Technique for Authentication of Wooden Panel Paintings. Sensors, 16(6), 881. doi:10.3390/s16060881Tian, G. Y., Lu, R. S., & Gledhill, D. (2007). Surface measurement using active vision and light scattering. Optics and Lasers in Engineering, 45(1), 131-139. doi:10.1016/j.optlaseng.2006.03.005Secher, J. J., Darvann, T. A., & Pinholt, E. M. (2017). Accuracy and reproducibility of the DAVID SLS-2 scanner in three-dimensional facial imaging. Journal of Cranio-Maxillofacial Surgery, 45(10), 1662-1670. doi:10.1016/j.jcms.2017.07.006Luhmann, T. (2010). Close range photogrammetry for industrial applications. ISPRS Journal of Photogrammetry and Remote Sensing, 65(6), 558-569. doi:10.1016/j.isprsjprs.2010.06.003Hui, Z., Liyan, Z., Hongtao, W., & Jianfu, C. (2009). Surface Measurement Based on Instantaneous Random Illumination. Chinese Journal of Aeronautics, 22(3), 316-324. doi:10.1016/s1000-9361(08)60105-3McPherron, S. P., Gernat, T., & Hublin, J.-J. (2009). Structured light scanning for high-resolution documentation of in situ archaeological finds. Journal of Archaeological Science, 36(1), 19-24. doi:10.1016/j.jas.2008.06.028Arias, P., Herráez, J., Lorenzo, H., & Ordóñez, C. (2005). Control of structural problems in cultural heritage monuments using close-range photogrammetry and computer methods. Computers & Structures, 83(21-22), 1754-1766. doi:10.1016/j.compstruc.2005.02.018Patrucco, G., Rinaudo, F., & Spreafico, A. (2019). A NEW HANDHELD SCANNER FOR 3D SURVEY OF SMALL ARTIFACTS: THE STONEX F6. The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, XLII-2/W15, 895-901. doi:10.5194/isprs-archives-xlii-2-w15-895-2019Guidi, G., Atzeni, C., Seracini, M., & Lazzari, S. (2004). Painting Survey by 3D Optical Scanning - The Case ofAdoration of the Magiby Leonardo Da Vinci. Studies in Conservation, 49(1), 1-12. doi:10.1179/sic.2004.49.1.1Palma, G., Pingi, P., Siotto, E., Bellucci, R., Guidi, G., & Scopigno, R. (2019). Deformation analysis of Leonardo da Vinci’s «Adorazione dei Magi» through temporal unrelated 3D digitization. Journal of Cultural Heritage, 38, 174-185. doi:10.1016/j.culher.2018.11.001Batlle, J., Mouaddib, E., & Salvi, J. (1998). Recent progress in coded structured light as a technique to solve the correspondence problem. Pattern Recognition, 31(7), 963-982. doi:10.1016/s0031-3203(97)00074-5Salvi, J., Pagès, J., & Batlle, J. (2004). Pattern codification strategies in structured light systems. Pattern Recognition, 37(4), 827-849. doi:10.1016/j.patcog.2003.10.002DAVID SLS-1 FLYER http://kvejborg.dk/media/1245/flyer-web.pdfCloudCompare (Version 2.6) [GPL Software] http://www.cloudcompare.org/Besl, P. J., & McKay, N. D. (1992). A method for registration of 3-D shapes. IEEE Transactions on Pattern Analysis and Machine Intelligence, 14(2), 239-256. doi:10.1109/34.121791Gold, S., Rangarajan, A., Lu, C.-P., Pappu, S., & Mjolsness, E. (1998). New algorithms for 2D and 3D point matching. Pattern Recognition, 31(8), 1019-1031. doi:10.1016/s0031-3203(98)80010-1Bing Jian, & Vemuri, B. C. (2011). Robust Point Set Registration Using Gaussian Mixture Models. IEEE Transactions on Pattern Analysis and Machine Intelligence, 33(8), 1633-1645. doi:10.1109/tpami.2010.223Oomori, S., Nishida, T., & Kurogi, S. (2016). Point cloud matching using singular value decomposition. Artificial Life and Robotics, 21(2), 149-154. doi:10.1007/s10015-016-0265-xZhu, H., Guo, B., Zou, K., Li, Y., Yuen, K.-V., Mihaylova, L., & Leung, H. (2019). A Review of Point Set Registration: From Pairwise Registration to Groupwise Registration. Sensors, 19(5), 1191. doi:10.3390/s19051191Lin, C.-C., Tai, Y.-C., Lee, J.-J., & Chen, Y.-S. (2017). A novel point cloud registration using 2D image features. EURASIP Journal on Advances in Signal Processing, 2017(1). doi:10.1186/s13634-016-0435-yAbate, D. (2019). Documentation of paintings restoration through photogrammetry and change detection algorithms. Heritage Science, 7(1). doi:10.1186/s40494-019-0257-

Subjective assessment of university classroom environment

[EN] Research into the design of learning environments is warranted as the classroom space impacts on students' wellbeing and learning performance. Studies on subjective evaluation of classrooms usually focus on the influence of more objective aspects like temperature, light, sound, etc., based on concepts or attributes defined by experts. Thus, the attributes used to find relations with design parameters might not be recognised by users, thereby conditioning the evaluation process itself. This paper aims to analyse students' affective response to a university classroom in their own words, and then, after obtaining the semantic space, to identify the design elements that generate a positive affective response. This analysis was carried out implementing the Semantic Differential method in the framework of Kansei Engineering. A sample of 918 university students was assessed in situ in 30 university classrooms. The results show that students' affective structure in relation to their classroom comprises six independent factors: functionality and layout, cosy and pleasant, concentration and comfort, modern design, daylight and outward facing, and artificial lighting. From these factors, efforts to improve the classroom environment should be directed mainly towards two aspects: improving classroom functionality-layout, which is significantly related to the work space allocated to students; and the sensation of cosy-pleasant which is generated by all the classroom design parameters, but in particular, those that refer to the relationship of the classroom with the outdoor environment.This research was supported by Ministerio de Economia y Competitividad, Spain (project TIN2013-45736-R)Castilla-Cabanes, N.; Llinares Millán, MDC.; Bravo, JM.; Blanca Giménez, V. (2017). Subjective assessment of university classroom environment. Building and Environment. 122:72-81. https://doi.org/10.1016/j.buildenv.2017.06.004S728112

Acceso a jeringas estériles entre los jóvenes de Madrid y Barcelona que se inyectan drogas y su asociación con las prácticas de riesgo

[EN] To evaluate access to sterile syringes and its association with injection risk behaviour in Madrid and Barcelona. Cross-sectional community study by computer-assisted personal interview in 465 young heroin injectors between 2001 and 2003. Some 4.2% had not obtained any free sterile syringes in the previous 12 months. In Madrid 32.1% had obtained all their sterile syringes free of charge (ASSF), versus 44.6% in Barcelona (p<0.01). Not sharing (not using syringes used by someone else and not front/backloading) was associated with obtaining ASSF (OR=1.69) and with sporadic injection (OR=1.83). Not reusing one's own syringes was associated with the same two variables (OR=4.02 and OR=2.50, respectively). Access to sterile syringes is very high in Madrid and Barcelona, although the two cities have different approaches. The acquisition of all syringes free of charge should be facilitated, especially among frequent injectors. [ES] Evaluar el acceso a jeringas estériles y su asociación con prácticas de inyección de riesgo en Madrid y Barcelona. Material y método: Estudio transversal en la comunidad de 465 jóvenes que se inyectan heroína, realizado entre 2001 y 2003, mediante entrevista asistida por ordenador. Un 4,2% no obtuvo jeringas estériles gratuitas en los últimos 12 meses. En Madrid, el 32,1% obtuvo todas las jeringas estériles gratis (TJEG), frente al 44,6% de Barcelona (p < 0,01). No compartir (no utilizar jeringas ajenas usadas o droga diluida en las usadas por otros) se asoció con obtener TJEG (odds ratio [OR] = 1,69) e inyectarse esporádicamente (OR = 1,83). No reutilizar las jeringas propias se asoció con las mismas variables (OR = 4,02 y OR = 2,50, respectivamente). En Madrid y Barcelona el acceso a jeringas estériles es muy elevado, aunque con modelos diferentes. Debe facilitarse la obtención de todas las jeringas estériles gratis, especialmente entre los jóvenes que se inyectan con mayor frecuencia.This research was financed primarily by the Fundación para Investigación y la Prevención del Sida en España (FIPSE 3035/99 - Foundation for AIDS Research and Prevention in Spain); the analysis was possible thanks to the support of the Ciber de Epidemiología y Salud Pública.S