Stepping outside the neighborhood of T_c at LHC

"As you are well aware, many in the RHIC community are interested in the LHC heavy-ion program, but have several questions: What can we learn at the LHC that is qualitatively new? Are collisions at LHC similar to RHIC ones, just with a somewhat hotter/denser initial state? If not, why not? These questions are asked in good faith, and this talk is an opportunity to answer them directly to much of the RHIC community." With these words, the organizers of Quark Matter 2009 in Knoxville invited me to discuss the physics opportunities for heavy ion collisions at the LHC without recalling the standard arguments, which are mainly based on the extended kinematic reach of the machine. In response, I emphasize here that lattice QCD indicates characteristic qualitative differences between thermal physics in the neighborhood of the critical temperature (T_c < T < 400 - 500 MeV) and thermal physics at higher temperatures (T > 400-500 MeV), for which the relevant energy densities will be solely attainable at the LHC.Comment: 7 pages LaTeX, 4 eps-figures, Proceedings of the Quark Matter 09 conference in Knoxville, TN; small revisions in reply to referee repor

Physical activity and health – what are the recommendations and where do we find the Swiss population?

Since 1999 Switzerland has physical activity recommendations for adults, since 2006 also for school-age children and adolescents. The best available estimates indicate that 32% of adults meet the recommendations for three endurance-type training sessions and another 9% the minimal recommendations of half an hour moderate intensity physical activity on most days of the week. 13% of Swiss adolescents seem to meet the minimal recommendations of one hour on every day of the week, 35% on five days per week. These data rely on standardised, nationally representative surveys providing robust estimates, but they are based on self-report instruments of untested, poor or questionable validity against objective measurements of physical activity. No nationally representative data is available on compliance of children with the recommendations. Physical activity recommendations for all age groups in Switzerland should be reviewed in the light of the WHO recommendations expected for 2010. Established national surveys should be continued to allow the description of trends. In addition, physical activity behaviour of children and other age groups should be assessed using internationally standardised and nationally validated questionnaires and objective measurements. The feasibility of physiological measurements at the population level should be explored

Assessment of intensity, prevalence and duration of everyday activities in Swiss school children: a cross-sectional analysis of accelerometer and diary data

BACKGROUND: Appropriately measuring habitual physical activity (PA) in children is a major challenge. Questionnaires and accelerometers are the most widely used instruments but both have well-known limitations. The aims of this study were to determine activity type/mode and to quantify intensity and duration of children's everyday PA by combining information of a time activity diary with accelerometer measurements and to assess differences by gender and age. METHODS: School children (n = 189) aged 6/7 years, 9/10 years and 13/14 years wore accelerometers during one week in winter 2004 and one in summer 2005. Simultaneously, they completed a newly developed time-activity diary during 4 days per week recording different activities performed during each 15 min interval. For each specific activity, the mean intensity (accelerometer counts/min), mean duration per day (min/d) and proportion of involved children were calculated using linear regression models. RESULTS: For the full range of activities, boys accumulated more mean counts/min than girls. Adolescents spent more time in high intensity sports activities than younger children (p < 0.001) but this increase was compensated by a reduction in time spent playing vigorously (p = 0.04). In addition, adolescents spent significantly more time in sedentary activities (p < 0.001) and accumulated less counts/min during these activities than younger children (p = 0.007). Among moderate to vigorous activities, children spent most time with vigorous play (43 min/day) and active transportation (56 min/day). CONCLUSION: The combination of accelerometers and time activity diaries provides insight into age and gender related differences in PA. This information is warranted to efficiently guide and evaluate PA promotion

Regional differences of physical activity and sedentary behaviour in Swiss children are not explained by socio-demographics or the built environment

Objective We evaluated whether regional differences in physical activity (PA) and sedentary behaviour (SB) existed along language boundaries within Switzerland and whether potential differences would be explained by sociodemographics or environmental characteristics. Methods We combined data of 611 children aged 4 to 7 years from four regional studies. PA and SB were assessed by accelerometers. Information about the socio-demographic background was obtained by questionnaires. Objective neighbourhood attributes could be linked to home addresses. Multivariate regression models were used to test associations between PA and SB and socio-demographic characteristics and neighbourhood attributes. Results Children from the German compared to the French-speaking region were more physically active and less sedentary (by 10–15 %, p\0.01). Although Germanspeaking children lived in a more favourable environment and a higher socioeconomic neighbourhood (differences p\0.001), these characteristics did not explain the differences in PA behaviour between French and German speaking. Conclusions Factors related to the language region, which might be culturally rooted were among the strongest correlates of PA and SB among Swiss children, independent of individual, social and environmental factors

From bubbles to foam: dilute to dense evolution of hadronic wave function at high energy

We derive the evolution of a hadronic light cone wave function with energy at weak coupling. Our derivation is valid both in the high and the low partonic density limit, and thus encompasses both the JIMWLK and the KLWMIJ evolution. The hadronic wave function is shown to evolve by the action of the Bogoliubov-type operator, which diagonalizes on the soft gluon sector the light-cone hamiltonian in the presence of an arbitrary valence charge density. We find explicitly the action of this operator on the soft as well as the valence degrees of freedom of the theory.Comment: 30 page

Decline of Ambient Air Pollution Levels and Improved Respiratory Health in Swiss Children

The causality of observed associations between air pollution and respiratory health in children is still subject to debate. If reduced air pollution exposure resulted in improved respiratory health of children, this would argue in favor of a causal relation. We investigated whether a rather moderate decline of air pollution levels in the 1990s in Switzerland was associated with a reduction in respiratory symptoms and diseases in school children. In nine Swiss communities, 9,591 children participated in cross-sectional health assessments between 1992 and 2001. Their parents completed identical questionnaires on health status and covariates. We assigned to each child an estimate of regional particles with an aerodynamic diameter < 10 μg/m(3) (PM(10)) and determined change in PM(10) since the first survey. Adjusted for socioeconomic, health-related, and indoor factors, declining PM(10) was associated in logistic regression models with declining prevalence of chronic cough [odds ratio (OR) per 10-μg/m(3) decline = 0.65, 95% confidence interval (CI), 0.54–0.79], bronchitis (OR = 0.66; 95% CI, 0.55–0.80), common cold (OR = 0.78; 95% CI, 0.68–0.89), nocturnal dry cough (OR = 0.70; 95% CI, 0.60–0.83), and conjunctivitis symptoms (OR = 0.81; 95% CI, 0.70–0.95). Changes in prevalence of sneezing during pollen season, asthma, and hay fever were not associated with the PM(10) reduction. Our findings show that the reduction of air pollution exposures contributes to improved respiratory health in children. No threshold of adverse effects of PM(10) was apparent because we observed the beneficial effects for relatively small changes of rather moderate air pollution levels. Current air pollution levels in Switzerland still exceed limit values of the Swiss Clean Air Act; thus, children’s health can be improved further

Fluctuations and Correlations of net baryon number, electric charge, and strangeness: A comparison of lattice QCD results with the hadron resonance gas model

We calculate the quadratic fluctuations of net baryon number, electric charge and strangeness as well as correlations among these conserved charges in (2+1)-flavor lattice QCD at zero chemical potential. Results are obtained using calculations with tree level improved gauge and the highly improved staggered quark (HISQ) actions with almost physical light and strange quark masses at three different values of the lattice cut-off. Our choice of parameters corresponds to a value of 160 MeV for the lightest pseudo scalar Goldstone mass and a physical value of the kaon mass. The three diagonal charge susceptibilities and the correlations among conserved charges have been extrapolated to the continuum limit in the temperature interval 150 MeV <T < 250 MeV. We compare our results with the hadron resonance gas (HRG) model calculations and find agreement with HRG model results only for temperatures T<= 150 MeV. We observe significant deviations in the temperature range 160 MeV < T < 170 MeV and qualitative differences in the behavior of the three conserved charge sectors. At T < 160 MeV quadratic net baryon number fluctuations in QCD agree with HRG model calculations while, the net electric charge fluctuations in QCD are about 10% smaller and net strangeness fluctuations are about 20% larger. These findings are relevant to the discussion of freeze-out conditions in relativistic heavy ion collisions.Comment: 17 pages, 18 EPS-files, 5 tables, revised version includes continuum limit extrapolations of off-diagonal susceptibilities, to appear in Phys. Rev.

Nonlinear QCD Evolution: Saturation without Unitarization

We consider the perturbative description of saturation based on the nonlinear QCD evolution equation of Balitsky and Kovchegov (BK). Although the nonlinear corrections lead to saturation of the scattering amplitude locally in impact parameter space, we show that they do not unitarize the total cross section. The total cross section for the scattering of a strongly interacting probe on a hadronic target is found to grow exponentially with rapidity. The origin of this violation of unitarity is the presence of long range Coulomb fields away from the saturation region. The growth of these fields with rapidity is not tempered by the nonlinearity of the BK equation.Comment: 4 pages, RevTe

Podoplanin-positive cells are a hallmark of encapsulating peritoneal sclerosis

Background. Encapsulating peritoneal sclerosis (EPS) and simple peritoneal sclerosis are important complications of long-term peritoneal dialysis (PD). Podoplanin is expressed by mesothelial cells and lymphatic vessels, which are involved in inflammatory reactions in the peritoneal cavity. Methods. We studied 69 peritoneal biopsies from patients on PD (n = 16), patients with EPS (n = 18) and control biopsies taken at the time of hernia repair (n = 15) or appendectomy (n = 20). Immunohistochemistry was performed to localize podoplanin. Additionally, markers of endothelial cells, mesothelial cells, myofibroblasts (smooth muscle actin), proliferating cells, and double labelling for smooth muscle actin/podoplanin were used on selected biopsies. Results. Podoplanin was present on the endothelium of lymphatic vessels in the submesothelial fibrous tissue and on mesothelial cells. In patients on PD and in biopsies with appendicitis, the mesothelial cells demonstrated a cuboidal appearance and circumferential podoplanin staining, with gaps between the cells. The number of lymphatic vessels was variable, but prominent at sites of fibrosis. In patients with EPS, a diffuse infiltration of podoplanin-positive cells with a fibroblastic appearance was present in 15 out of 18 biopsies. This pattern was focally present in 3 out of 16 on PD and none in the 35 controls. The podoplanin-positive cells did not express the endothelial marker or the mesothelial marker (calretinin). Conclusions. EPS is characterized by a population of podoplanin and smooth muscle actin double-positive cells. Podoplanin might be a suitable morphological marker supporting the diagnosis and might be involved in the pathogenesis of EP

Reduced Real-life Affective Well-being and Amygdala Habituation in Unmedicated Community Individuals at Risk for Depression and Anxiety

Background: Early identification of risk for depression and anxiety disorders is important for prevention, but real-life affective well-being and its biological underpinnings in the population remain understudied. Here, we combined methods from epidemiology, psychology, ecological momentary assessment, and functional magnetic resonance imaging to study real-life and neural affective functions in individuals with subclinical anxiety and depression from a population-based cohort of young adults. Methods: We examined psychological measures, real-life affective valence, functional magnetic resonance imaging amygdala habituation to negative affective stimuli, and the relevance of neural readouts for daily-life affective function in 132 non–help-seeking community individuals. We compared psychological and ecological momentary assessment measures of 61 unmedicated individuals at clinical risk for depression and anxiety (operationalized as subthreshold depression and anxiety symptoms or a former mood or anxiety disorder) with those of 48 nonrisk individuals and 23 persons with a mood or anxiety disorder. We studied risk-associated functional magnetic resonance imaging signals in subsamples with balanced sociodemographic and image quality parameters (26 nonrisk, 26 at-risk persons). Results: Compared with nonrisk persons, at-risk individuals showed significantly decreased real-life affective valence (p = .038), reduced amygdala habituation (familywise error–corrected p = .024, region of interest corrected), and an intermediate psychological risk profile. Amygdala habituation predicted real-life affective valence in control subjects but not in participants at risk (familywise error–corrected p = .005, region of interest corrected). Conclusions: Our data suggest real-life and neural markers for affective alterations in unmedicated community individuals at risk for depression and anxiety and highlight the significance of amygdala habituation measures for the momentary affective experience in real-world environments