9 research outputs found
Supplementary data from: The gut microbiome in patients with Cushing’s syndrome is severely altered
- Author
- Publication venue
- Publication date
- 11/07/2022
- Field of study
HASH(0x7f8d2ce94b88
Supplementary data from: Adrenal venous sampling (AVS) in Primary Bilateral Macronodular Adrenocortical Hyperplasia (PBMAH): A study of 16 patients
- Author
- Publication venue
- Publication date
- 10/04/2021
- Field of study
Adrenal venous sampling in primary bilateral macronodular adrenocortical hyperplasi
Time to diagnosis in Cushing’s syndrome: A meta-analysis based on 5367 patients
- Author
- Bansal Prachi
- Barahona María-José
- Beuschlein Felix
- Braun Leah Theresa
- Cosaro Elisa
- Dogansen Sema Ciftci
- Elenkova Atanaska
- Hanzu Felicia Alexandra
- Hoster Eva
- Johnston Philip C.
- Kreitschmann-Andermahr Ilonka
- Losa Marco
- Machado Márcio Carlos
- Osswald Andrea
- Raftopoulos Christian
- Reincke Martin
- Riester Anna
- Ritzel Katrin
- Rubinstein German
- Santos de Oliveira Ricardo
- Scaroni Carla
- Schopohl Jochen
- Storr Helen L.
- Valassi Elena
- van der Werff Steven J.A.
- Zacharieva Sabina
- Zopp Stephanie
- Publication venue
- Publication date
- 01/06/2019
- Field of study
The time from first symptom to diagnosis of Cushing's syndrome is considered relevant for the severity of phenotype at presentation and long-term outcome. We therefore performed a systematic literature search to investigate relevant factors associated with a short time to diagnosis. The meta-analysis of 45 studies with 5560 patients showed significant differences for adrenal Cushing’s syndrome, Cushing’s disease and the ectopic Cushing’s syndrome. We did not find difference for gender, age or time of publication
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two
- Author
- Abassi Yama
- Abelin Jennifer G
- Abolhalaj Milad
- Abraham Tara S
- Adam Ammar
- Adams David
- Adams Homer
- Adams Sarah F
- Adamus Tomasz
- Addepalli Murali
- Addepalli Murali
- Adjei Alex A
- Agapova Larissa
- Agarwala Sanjiv
- Ager Casey
- Aggarwal Charu
- Agnello Giulia
- Agudo Judith
- Aguilar Ethan G
- Aguilera Todd
- Ahamadi Malidi
- Ahn Yong-Oon
- Ahrens Eric T
- Aizer Ayal
- Ajina Reham
- Akerley Wallace
- Al-Muftah Mariam
- Albershardt Tina C
- Albershardt Tina C
- Albrekt Ann-Sofie
- Alekar Shilpa
- Alemany Ramon
- Alemany Ramon
- Alexander Brian
- Allbritton Omaira
- Allen Clint T
- Alley Evan W
- Allison James
- Allison James
- Allison James
- Alston Tesha
- Alt Jürgen
- Alters Susan
- Amatulli Michael
- Anand Snjezana
- Anand Snjezana
- Anand Snjezana
- Anderson Clark
- Anderson Mark
- Andersson Bengt
- Andre Pascale
- Andtbacka Robert H I
- Andtbacka Robert H I
- Angiuoli Sam
- Ansari Tameem
- Anthony Scott
- Antonarakis Emmanuel S
- Antonia Scott J
- Anwar Firoz
- Aquino-Michaels Keston
- Archer Jacob F
- Arina Ainhoa
- Armand Philippe
- Armenta Paul
- Armet Caroline M
- Arnoux Thomas
- Ascarateil Stephane
- Askmyr David
- Atkins Michael
- Atkins Michael B
- Atkinson Victoria
- Au Katrina
- Autio Karen A
- Awad Mark
- Bagarazzi Mark
- Bai Dina
- Baia Gilson
- Baird Jason
- Bajaj Anshika
- Balatoni Timea
- Balboni Tracy
- Balch Leslie
- Bang Andrew
- Bao Riyue
- Bao Yangyi
- Bao Yangyi
- Barakat David
- Barberi Theresa
- Barker Christopher A
- Barnea Eytan
- Barras David
- Bartkowiak Todd
- Bartlett David
- Bartlett David
- Bartlett David
- Bartlett David
- Barton Sunjay M
- Barve Minal
- Bauer Todd
- Bauer Todd W
- Bauman Julie
- Baumgaertner Petra
- Bauml Joshua
- Beceren-Braun Figen
- Beck Kristen
- Becker Annette
- Beckers Johannes
- Beckett Michael A
- Bedognetti Davide
- Bedognetti Davide
- Bedognetti Davide
- Bell Bryan
- Bell Charles J M
- Bell Peter
- Beltran Pedro
- Bender Lewis H
- Bender Steven
- Bennett Mark K
- Benz Steven
- Bera Tapan
- Berglund Peter
- Berglund Peter
- Berkey Sara
- Bernatchez Chantale
- Berry John S
- Berzofsky Jay A
- Bhardwaj Nina
- Bian Zhen
- Bianco Alberto
- Biediger Ronald J
- Bifulco Carlo
- Bigley Alison
- Bingham Patrick
- Biniszkiewicz Detlev M
- Bischoff Helge
- Blake Zoe
- Blake Zoe
- Blakely Collin
- Blazar Bruce R
- Blogowski Wojciech
- Bloom Anja C
- Boehm Jesse
- Bokovanov Vladimir
- Bommareddy Praveen K
- Bommareddy Praveen K
- Bommareddy Praveen K
- Bommareddy Praveen K
- Booth Jamie
- Bornschlegl Svetlana
- Bose Nandita
- Bossenmaier Birgit
- Boughorbel Sabri
- Boyer Jean
- Bramante Simona
- Branstetter Daniel
- Brech Dorothee
- Brenin David
- Broaddus V. C
- Brockstedt Dirk G
- Brockstedt Dirk G
- Brody Joshua
- Bronson Roderick
- Brooks Alan
- Brooks Alan D
- Broucek Joseph
- Brown Alice
- Brown Brian
- Brown Brittany
- Brown Gail L
- Brown Sheila
- Bruce Jeffrey N
- Brunet Laura R
- Bruno Tullia C
- Bryan Jennifer
- Bryant Richard
- Buchbinder Elizabeth
- Bucsek Mark
- Budhu Sadna
- Budhu Sadna
- Budkowska Marta
- Bueno Raphael
- Buettner Florian
- Buettner Nico
- Bullock Kim
- Bullock Kim
- Burova Elena
- Burrill Joel
- Bussler Holm
- Butterfield Lisa H
- Butterfield Lisa H
- Byrne-Steele Miranda
- Cagney Daniel
- Calderon Hugo
- Callahan Margaret K
- Campesato Luis F
- Campogan Dwayne
- Cao Felicia
- Capasso Cristian
- Capasso Cristian
- Caplazi Patrick
- Cappuccini Federica
- Carcaboso Angel M
- Carlino Matteo S
- Carpi Sara
- Carrasco Ruben
- Carrera Diego A
- Carrero Rosa M S
- Carson Dennis A
- Castellini Laura
- Cathomas Richard
- Cauvin Annick
- Cauwenberghs Sandra
- Caux Christophe
- Cebon Jonathan S
- Ceccarelli Michele
- Celis Esteban
- Cerignoli Fabio
- Cerullo Vincenzo
- Cerullo Vincenzo
- Cervera-Carrascón Víctor
- Cesareni Gianni
- Cha John
- Cha John
- Cha John
- Champion Brian
- Chan Anissa S H
- Chan Chanty
- Chan Chanty
- Chan Ivan
- Chan Leo
- Chan Timothy A
- Chang Alfred E
- Chang Alfred E
- Chang Joe
- Chang Nancy N
- Chang Thomas
- Chanuc Fabien
- Chapelin Fanny
- Chaplin Jenny
- Chappel Scott C
- Charych Deborah H
- Charych Deborah H
- Chaudhuri Amitabha
- Chaussabel Damien
- Chen Ada
- Chen Ada
- Chen Gang
- Chen Jason
- Chen Jason
- Chen Xiaomu
- Chen Xin
- Chen Xiufen
- Chen Yu
- Chen Yu
- Chenchik Alex
- Chheda Zinal
- Chiang Eugene
- Chikina Maria
- Chittenden Thomas
- Chiu Hsiling
- Cho Charles
- Chongyung Fang
- Chou Margaret
- Choueiri Toni K
- Choy Carmen
- Clark Joseph I
- Clavijo Paul E
- Clifton Guy T
- Clynes Raphael
- Cobbold Mark
- Cobbold Mark
- Cobbold Mark
- Coder Brandon
- Coffman Robert L
- Cohen Cyrille
- Cohen Ezra E W
- Cohen Roger
- Colen Rivka
- Colevas A. D
- Collins Natalie
- Colrain Jillian
- Coltharp Carla
- Concha-Benavente Fernando
- Connolly Eileen P
- Conwell Darwin
- Conwell Darwin
- Corrales Leticia P
- Corrales Leticia P
- Coukos George
- Coukos George
- Coussens Lisa M
- Coussens Lisa M
- Craggs Graham
- Craig Andrew
- Crittenden Marka
- Cron Kyle R
- Cronstein Bruce N
- Crooks James
- Crosby Andrea
- Crosignani Stefano
- Crowder Robert
- Cruickshank Scott
- Csuka Orsolya
- Curbishley Stuart
- Curiel Tyler
- Curran Emily
- Curran Michael
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- Curti Brendan
- Da Costa Andre
- Dai Fu
- Dai Jie
- Dai Peihong
- Dalgleish Angus
- Dalvie Deepak
- Daniels Gregory A
- Daud Adil
- David Justin M
- Davies Bronwyn
- de Boisferon Marc H
- de Groot Patricia
- de Gruijl Tanja
- De Henau Olivier
- de Leon Laura
- De Maeseneire Coraline
- De Sanctis Francesco
- de Silva Suresh
- Deacon Donna
- Deacon Donna H
- DeBenedette Mark
- DeBenedette Mark
- Declerck Paul
- Decock Julie
- Decock Julie
- DeFalco Jeff
- Dela Cruz Filemon
- Delgoffe Greg
- Delgoffe Greg M
- Delgoffe Greg M
- Delgoffe Greg M
- Delogu Lucia
- Delorenzi Mauro
- Demaria Sandra
- Demaria Sandra
- Deng Liang
- Deng Weiwen
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- Denis Caroline
- Desbien Anthony L
- deVries Michele
- Dhupkar Pooja
- Diab Adi
- Diab Adi
- Diab Adi
- Diaz Luis
- DiCostanzo AriCeli
- Diede Scott J
- Dietz Allan B
- Dillhoff Mary
- Dillon Patrick
- Dilworth Ryan
- Dimberg Anna
- Ding Yueyun
- Doberstein Stephen K
- Dobkin Julie
- Doener Fatma
- Dolegowska Barbara
- Doleschall Zoltan
- Doman Thompson
- Dominguez George
- Donahue Renee
- Donahue Renee
- Dorsey Frank C
- Dovedi Simon
- Downs-Canner Stephanie
- Drake Charles
- Drake Charles G
- Drake Charles G
- Driessens Gregory
- Driscoll Kyla
- Druker Brian J
- Dubensky Thomas W
- Dubensky Thomas W
- Dudimah Duafalia
- Duff Susan
- Dumontet Charles
- Dunai Cordelia
- Dunai Cordelia
- Dutcher Janice P
- Duttagupta Priyanka
- Duvvuri Uma
- Dyson Mike
- D’Apuzzo Massimo
- Ebner Peggy
- Edwards Robert
- Edwards Robert P
- Edwards Robert P
- Eickhoff Jens
- Eisenhower Mary
- El Alaoui Meddy
- El Alaoui Said
- Eles Klara
- Ellies Lesley
- Elnaggar Omar
- Elvecrog James
- Emberley Ethan
- Emerling Daniel
- Eng Charis
- Engelhard Victor H
- English Jessie
- Enstrom Amanda
- Eremeev Artem
- Eriksson Emma
- Eriksson Emma
- Eriksson Emma
- Ertelt Kathleen
- Eswarappa Rajesh
- Evans Elizabeth
- Evans Kathy
- Facciabene Andrea
- Facciabene Andrea
- Facciabene Andrea
- Facciponte John
- Facciponte John
- Falchook Gerald
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- Fantini Massimo
- Fantini Massimo
- Farkas Emil
- Farren Matthew
- Faustman Denise
- Fa’ak Faisal
- Fa’ak Faisal
- Femel Julia
- Feng JunLi
- Feng Yan
- Feng Zipei
- Feola Sara
- Fernandez Christian
- Fernando Ingrid
- Ferris Robert L
- Ferris Robert L
- Ferris Robert L
- Ferris Robert L
- Fesenkova Valentyna
- Field Jessica J
- Fisher Kerry
- Fisher Terry
- Fitzharris Bernie
- Flano Emilio
- Flechtner Jessica B
- Flies Dallas B
- Flynn Patrick
- Fogler William
- Fong Lawrence
- Formenti Silvia C
- Formenti Silvia C
- Foster Cathie
- Foster Rosemary
- Fotin-Mleczek Mariola
- Fox Bernard
- Francica Brian
- Francis Julie-Ann
- Frangou Costa
- Franklin Marilyn
- Franklin Wilbur
- Frascaro Federica
- Fraser Kathryn
- Frederix Kim
- Freimark Bruce
- Freimark Bruce
- Freimark Bruce
- Frey Alan
- Fridman Leticia
- Friedman Alan
- Friedman David
- Fromm George
- Früh Martin
- Fu Yang-Xin
- Fu Yichun
- Fu Yichun
- Fuertes Marraco Silvia A
- Fugle Caroline W
- Fuhrmann Steven
- Fukaya Satoshi
- Fulton Noreen
- Fuoco Claudia
- Fusciello Manlio
- Fuseri Nicolas
- Gabitzsch Elizabeth
- Gabrail Nashat
- Gabrilovich Dmitry
- Gajewski Thomas
- Gajewski Thomas F
- Gajewski Thomas F
- Gajewski Thomas F
- Gajewski Thomas F
- Gajewski Thomas F
- Gajewski Thomas F
- Galeassi Nadejda
- Gamble Alicia
- Gamble Alicia
- Gameiro Sofia
- Gameiro Sofia R
- Gandhi Anita
- Gao Chan
- Gardai Shyra J
- Gardner Kellie
- Gartrell Robyn
- Gartrell Robyn
- Gartrell Robyn
- Gasmi Billel
- Gastineau Dennis A
- Gaughan Elizabeth
- Gauthier Audrey
- Gauthier Kelsey S
- Geissler Michael
- Gergel Ivan
- Geukens Nick
- Gfeller David
- Ghadially Hormas
- Ghamsari Lila
- Ghandi Leena
- Ghisoli Maurizio
- Giaccia Amato
- Gibney Geoffrey
- Giffin Louise
- Gillies Stephen D
- Giri Sanjeev
- Gladstone Douglas
- Glickman Laura H
- Gnad-Vogt Ulrike
- Godwin John
- Gomes Bruno
- Gong Jian
- Gong Jian
- Gonzales Rodney J M
- Gooding William
- Gooding William
- Goodman Reid
- Gopal Ajay
- Gordon Keith
- Gordon Nancy
- Gottschalk Stephen
- Gough Michael
- Gowda Nagaraj
- Goyal Sharad
- Graff Jeremy
- Graham Charles
- Graves Edward
- Gray Michael
- Gray Michael
- Greasley Samantha
- Greenberg Norman
- Greiff Lennart
- Greiner John W
- Grenga Italia
- Grenga Italia
- Gressett Monica M
- Griesinger Frank
- Grigoryeva Olga
- Grigsby Iwen
- Grivas Petros
- Grogan Elizabeth W
- Grogan Jane
- Grose Mark
- Grose Mark
- Grose Mark
- Grosh William
- Gross Matt
- Gross Matt
- Grossenbacher Steven K
- Grossmann Kenneth
- Gruber Harry
- Gu Xuemin
- Guenther Garret
- Guerriero Jennifer
- Gugel Elena G
- Guiducci Cristina
- Guirado Elizabeth
- Gulley James L
- Gunatilaka Leslie A A
- Guo Jie
- Guo Zeng-qing
- Gupta Ravi
- Gupta Sachin
- Gupta Sumati
- Gustafson Michael P
- Gutierrez Andres A
- Guttridge Denis
- Guy Emily I
- Guzman Wilson
- Hagihara Katsunobu
- Hagner Patrick
- Hailemichael Yared
- Hailemichael Yared
- Haining W. N
- Hale Diane F
- Hall Gerald
- Hallmeyer Sigrun
- Hamdy Freddie
- Hammond Scott A
- Han Jian
- Han Yanyan
- Hank Jacquelyn A
- Hanks Brent A
- Hanson Bill
- Harari Paul M
- Harbell Michael
- Hardin Mark O
- Hardwick James
- Harrington Kevin
- Harris Jaryse
- Harris-Bookman Sarah
- Hart Philip
- Hasapidis Jeannette
- Hassan Raffit
- Havel Jonathan
- Havunen Riikka
- Havunen Riikka
- Hayashi Tomoko
- Haymaker Cara
- Haynes Heather
- Heinze Clinton
- Hellmann Matthew D
- Hellmann Matthew D
- Hellmann Matthew D
- Hellström Ann-Charlotte
- Helming Laura
- Hemmi Silvio
- Hemminki Akseli
- Hemminki Akseli
- Hemminki Otto
- Hendrickx Wouter
- Hendrickx Wouter
- Hendrickx Wouter
- Henrich Ian
- Heo Dae S
- Herbert Garth S
- Herbst Ronald
- Heron Dwight
- Herranz Mireia U
- Hess Kenneth R
- Heymach John
- Higuchi Tomoe
- Hilbe Wolfgang
- Hill Adrian
- Hill Andrew G
- Hill Jonathan A
- Hillringhaus Lars
- Hipp Madeleine
- Hirschhorhn-Cymerman Daniel
- Ho Po
- Hoch Ute
- Hoch Ute
- Hoch Ute
- Hodge James
- Hodge James
- Hodge James W
- Hodi F. S
- Hodi F. S
- Hodi F. S
- Hofmeister Robert
- Holland Pamela M
- Hollevoet Kevin
- Hollingsworth Robert E
- Hollingsworth Robert E
- Holmgaard Rikke
- Holtzhausen Alisha
- Honarmand Somayeh
- Hong Bang-Xing
- Hong David
- Hong Henoch S
- Hong Peter
- Horst Basil
- Horton Brendan
- Horvath Szabolcs
- Hotson Andrew
- Hou Jinlin
- Hou Xiaohong
- Hou Yafei
- Howell Alan
- Hu Yangyang
- Hu Yangyang
- Hu-Lieskovan Siwen
- Hua Hong
- Huang Fei
- Huang Jing
- Huang Shiang
- Huang Shiang
- Huang Tony
- Huang Yuanhiu
- Huang Yuanhiu
- Hudson Thomas E
- Huelsmann Erica
- Huffman Austin P
- Humeau Laurent
- Hunt Donald F
- Hunt Donald F
- Hurt Elaine
- Hurt Elaine
- Hurwitz Michael
- Hutchins Jeff
- Hutchins Jeff
- Hutchins Jeff
- Hwu Patrick
- Hwu Wen-Jen
- Hylander Bonnie
- Ibrahim Nageatte
- Illingworth Sam
- Infante Jeffrey
- Ioffe Ella
- Irmler Martin
- Irving Bryan A
- Irving Bryan A
- Izaki Daisuke
- Jablons David
- Jablonski Sandra
- Jackson Doreen O
- Jackson Natalie
- Jacobson Caron
- Jacques Judy
- Jaen Juan C
- Jaen Juan C
- Jahan Naznin
- Jahan Thierry
- Jaini Ritika
- Jaiswal Ashvin
- Jameson Michael B
- Jang Dadi
- Janku Filip
- Janne Pasi A
- Janssen Louise
- Jarblad-Leja Justyna
- Jeraj Robert
- Jessen Katti
- Jhawar Sachin
- Jhawar Sachin
- Jia Dan T
- Jin Ming
- Johnson Brian
- Johnson Bruce D
- Johnson Karen
- Johnson Melissa L
- Jolly Douglas
- Joly Nathalie
- Jonas Adria
- Jones Frank
- Jones Jeremy
- Jones Sian
- Joshi Bharat H
- Ju Xiaoming
- Kadenhe-Chiweshe Angela
- Kaiser Stephen
- Kalinski Pawel
- Kalinski Pawel
- Kalinski Pawel
- Kalinski Pawel
- Kallen Karl-Josef
- Kalos Michael
- Kane Lawrence P
- Kanerva Anna
- Kang Kai
- Kangas Takashi O
- Kanne David B
- Kantrowitz Joel
- Kapp Kerstin
- Kapralova Marina
- Kariolis Mihalis
- Karlsson-Parra Alex
- Karpathy Roberta
- Karpov Andrey
- Kasibhatla Shailaja
- Kasler Miklos
- Katibah George
- Katibah George
- Kaufman David R
- Kaufman Howard L
- Kaufman Howard L
- Kaufman Howard L
- Kaufman Howard L
- Kaufman Howard L
- Kaufman Howard L
- Kaufman Howard L
- Kauh John S
- Kavanaugh W. M
- Kavanaugh W. M
- Keam Bhumsuk
- Kern Jeffrey
- Khalil Danny N
- Khong Hiep
- Khong Hung
- Khuat Lam T
- Khuat Lam T
- Kibel Adam S
- Kidder Koby
- Kim Chul-Ho
- Kim Dong-Wan
- Kim Dongkyoon
- Kim Seulki
- Kim Seungwon
- Kim Soyeon
- Kim Tae M
- Kindler Hedy L
- Kindt Erick
- Kirk Peter
- Kirksey Yolanda
- Kitaura Kazutaka
- Kleinerman Eugenie S
- Kler Jasdeep
- Kline Justin
- Klinke David J
- Klinkhardt Ute
- Klippel Anke
- Kluger Harriet
- Knapp Alyssa
- Knudson Karin M
- Knudson Karin M
- Koch Sven D
- Kodumudi Krithika
- Kohanbash Gary
- Kohlhapp Frederick
- Kohlhapp Frederick
- Kolarkar Shalini
- Kollmeier Jens
- Komar Hannah
- Komar Hannah M
- Komarov Andrey
- Konakova Marina
- Koong Albert
- Korman Alan J
- Kornbluth Richard S
- Kortylewski Marcin
- Kortylewski Marcin
- Kosaka Yoko
- Kosoff Rachelle
- Kostarelos Kostas
- Koti Madhuri
- Kotlan Beatrix
- Koziol Marie E
- Kradjian Giorgio
- Krasovskaia Liudmila
- Kraus Manfred
- Kraynyak Kim
- Krejsa Cecile M
- Krishnan Monica
- Krishnan Suba
- Krisko John
- Kuai Rui
- Kumai Takumi
- Kumar Sushil
- Kumar Sushil
- Kumar Vikas
- Kumar Vikas
- Kung Andrew L
- Kunk Paul R
- Kuo Peiwen
- Kuppen Peter
- Kyruk Lukasz
- Laderas Ted
- Lai Venus
- Lake Andrew C
- Lamble Adam
- Lan Yan
- Lane Ryan
- Langowski John L
- Laport Ginna
- Lauer Peter
- Law Che-Leung
- Lazo Suzan
- Lazorchak Adam S
- Le Dung T
- Lee Dean
- Lee Jessica
- Lee Yu S
- Lehmann Paul
- Leidner Rom
- Leland Pamela
- Leleti Manmohan R
- Leleux Jardin
- Lemmens Edward E
- Lemmens Edward E
- Leonard John E
- Leonard John P
- Leonardo Steven
- Leong Justin L
- Leong Meredith L
- Leong Meredith L
- Lepone Lauren
- Lepone Lauren
- Leshem Jasmin
- Lesinski Gregory B
- Lesinski Gregory B
- Lesinski Gregory B
- Lessey-Morillon Elizabeth
- Letai Anthony
- Letellier Marie-Claire
- Levy Laurent
- Levy Ronald
- Lewis Whitney
- Li Jin
- Li Qiao
- Li Qiao
- Li Weiqun
- Li Wenlin
- Li Yanxia
- Li Yanyun
- Li Yanyun
- Li Zihai
- Liang Xiaoling
- Lieber Andre
- Lifke Alexander
- Lifke Valeria
- Lin Jing
- Lind Evan F
- Lindstedt Malin
- Lipson Evan
- Liszkay Gabriella
- Litton Jennifer
- Liu Bei
- Liu Biao
- Liu Cailian
- Liu Glenn
- Liu Hao
- Liu Hongtao
- Liu Linying
- Liu Matt
- Liu Shouchun
- Liu Shouchun
- Liu Shuming
- Liu Weiqun
- Liu Xiu-fen
- Liu Yuan
- Liu Zhuqing
- Liu Zhuqing
- Lo Kin-Ming
- Loibner Hans
- Long Georgina V
- Longo Dan
- Loriaux Marc
- Loskog Angelica
- Loskog Angelica
- Loskog Angelica
- Lossos Izidore S
- Lowe David
- Loya Matthew
- Lu Bo
- Lu Shanhong
- Lu Shanhong
- Lu Yan
- Lu Yan
- Lu Yan
- Ludwig Dale
- Ludwug Thomas
- Luke Jason
- Lum Lawrence G
- Lund Amanda W
- Lundberg Kristina
- Lykov Maxim
- López Fernando
- MacDonald Andrew
- MacDonald Cameron
- MacDonald Douglas
- Mace Thomas
- Mace Thomas
- Mace Thomas
- MacKinnon Andy
- MacKinnon Andy
- Maegley Karen
- Magee Michael S
- Magnani John L
- Makarov Vladimir
- Makhanov Michael
- Makhijani Neil
- Makkouk Amani
- Malaker Stacy A
- Malaker Stacy A
- Mallon Zach
- Mallow Crystal
- Malnassy Gregory
- Mandloi Nitin
- Mangin Eric
- Mangrolia Drishty
- Manguso Robert
- Manieri Nicholas
- Manning Luisa
- Manning-Bog Amy
- Manoharan Malini
- Manro Jason
- Mansfield David
- Marabelle Aurelien
- Marathi Upendra K
- Marelli Bo
- Marguier Gisele
- Marguier Gisele
- Maric Dragan
- Marillier Reece
- Marincola Francesco
- Marincola Franco M
- Marincola Franco M
- Market Robert V
- Marks Douglas
- Marron Thomas U
- Marshall Netonia
- Martin Allison
- Martins Beatriz
- Mason Sean
- Mastro Andrea
- Matsutani Takaji
- Mauceri Helena J
- Mauldin Ileana
- Maurer Matthew
- Mazzeo Christopher F
- McCafferty John
- McCaffery Ian
- McCarter Martin
- McCulley Kelsey
- McDaniel Amanda
- McDaniel Amanda
- McDaniel Amanda
- McDermott David F
- McDermott David F
- McIntosh Laura
- McKenna Jeffery M
- McNeel Douglas G
- McNeil Catriona
- McQuinn Christopher
- McWeeney Shannon
- McWhirter Sarah M
- Mediero Aranzazu
- Medina Daniel
- Meek Stephanie M
- Mehnert Janice
- Meier Roland
- Melcher Alan
- Melero Ignacio
- Melssen Marit
- Melssen Marit
- Mendoza Daniel
- Menk Ashley V
- Menk Ashley V
- Menk Ashley V
- Mennel Robert
- Mera Toshi
- Merghoub Taha
- Merghoub Taha
- Merghoub Taha
- Merghoub Taha
- Merghoub Taha
- Merrick Daniel
- Metchette Ken
- Metelli Alessandra
- Meyer Christina
- Meyers Michael L
- Milenova Ioanna
- Milenova Ioanna
- Millar David
- Miller Lance
- Miller Nichol
- Miller Peter
- Miller Richard
- Mitchell John
- Mitchell Leah
- Mitra Priyam
- Mittendorf Elizabeth A
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- Zappasodi Roberta
- Zappasodi Roberta
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- Zeh Herbert
- Zelenetz Andrew D
- Zeng Weiping
- Zeng Xue
- Zha Yuanyuan
- Zhang Danhui
- Zhang Jing
- Zhang Ping
- Zhang Qifang
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- Zhang Theresa
- Zhang Winter
- Zhang Yanping
- Zhao Fei
- Zhao Leyna
- Zhao Xingli
- Zheng Lianxing
- Zheng Wenxin
- Zheng Xianxian
- Zheng Yi
- Zhong Hong
- Zhou Li
- Zhou Xiangjun
- Zippelius Alfred
- Zloza Andrew
- Zloza Andrew
- Zloza Andrew
- Zloza Andrew
- Zloza Andrew
- Zou Jun
- Zuba-Surma Ewa
- Zubkova Olga
- Zureikat Amer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
Background
The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd.
Methods
We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background.
Results
First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001).
Conclusions
In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival
The role of adrenal venous sampling (AVS) in primary bilateral macronodular adrenocortical hyperplasia (PBMAH): a study of 16 patients
- Author
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/05/2022
- Field of study
OBJECTIVE
Primary bilateral macronodular adrenocortical hyperplasia (PBMAH) is a rare cause of ACTH-independent Cushing's syndrome. Current guidelines recommend bilateral adrenalectomy for PBMAH, but several studies showed clinical effectiveness of unilateral adrenalectomy despite bilateral disease in selected patients. Our aim was to evaluate the gain of information which can be obtained through adrenal venous sampling (AVS) based cortisol lateralization ratios for guidance of unilateral adrenalectomy.
DESIGN
We performed a retrospective analysis of 16 patients with PBMAH and clinical overt cortisol secretion in three centers METHODS: Selectivity of adrenal vein sampling during AVS was defined as a gradient of cortisol or a reference adrenal hormone ≥2.0 between adrenal and peripheral vein. Lateralization was assumed if the dominant to non-dominant ratio of cortisol to reference hormone was ≥4.0.
RESULTS
AVS was technically successful in all patients based on absolute cortisol levels and in 13 of 16 patients (81%) based on reference hormone levels. Lateralization was documented in 8 of 16 patients. In patients with lateralization, in 5 of 8 cases this occurred toward morphologically larger adrenals, while in 3 patients lateralization was present in bilaterally identical adrenals. The combined volume of adrenals correlated positively with urinary free cortisol, suggesting that adrenal size is the dominant determinant of cortisol secretion.
CONCLUSIONS
In this study the gain of information through AVS for unilateral adrenalectomy was limited in patients with PBMAH and marked adrenal asymmetry
Recommended from our members
CureGN Study Rationale, Design, and Methods: Establishing a Large Prospective Observational Study of Glomerular Disease
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- Achanti Anand
- Adler Sharon
- Ahn Wooin
- Al-Uzri Amira
- Alachkar Nada
- Ali Husain S
- Almaani Salem
- Alpers Charles
- Ambruzs Josephine
- Appel Gerald B
- Ashoor Isa
- Avila-Casado Carmen
- Aviles Diego
- Ayoub Isabelle
- Babayev Revekka
- Bagnasco Serena
- Baracco Rossana
- Barcia John
- Barisoni Laura
- Barisoni Laura
- Bartosh Sharon
- Batal Ibrahim
- Beil Charlotte
- Belsha Craig
- Bomback Andrew S
- Bomback Andrew S
- Bowers Corinna
- Bowers Corinna
- Braun Michael C
- Brede Emily
- Brown Elizabeth
- Brown Eric
- Budisavljevic Milos
- Cai Yi
- Campenot Eric S
- Canetta Pietro
- Canetta Pietro A
- Carlassara Lucrezia
- Cattran Dan
- Cattran Daniel
- Chan Brenda
- Chatterjee Debanjana
- Chernitskiy Vladimir
- Chishti Aftab
- Choi Michael
- Claes Donna
- Clark Kira
- Contreras Gabriel
- Cramer Carl
- D'Angelo Maggie
- Davis Keefe
- Delbarba Elisa
- Dell Katherine M
- Denburg Michelle
- Derebail Vimal
- Dewalt Darren
- Dogra Samriti
- Dukkipati Ram
- Dutcher Amy
- D’Agati Vivette
- D’Agati Vivette D
- Eikstadt Richard
- Erkan Elif
- Falk Ronald
- Falk Ronald J
- Fatima Huma
- Feig Daniel
- Fernandez Hilda
- Fervenza Fernando C
- Flessner Michael F
- Fogo Agnes
- Fornoni Alessia
- Foroncewicz Bartosz
- Freundlich Michael
- Gadegbeku Crystal
- Gaut Joseph
- Gbadegesin Rasheed
- Gharavi Ali G
- Gharavi Ali G
- Ghiggeri Gian Marco
- Gibson Keisha
- Gillespie Brenda
- Gillespie Brenda W
- Gipson Debbie S
- Gipson Debbie S
- Gipson Patrick
- Glenn Dorey
- Gonzalez-Zea Anny
- Graff John
- Greenbaum Larry A
- Greenbaum Larry A
- Guay-Woodford Lisa M
- Guay-Woodford Lisa M
- Hanna Melisha
- Hasely Leah
- Helmuth Margaret
- Helmuth Margaret
- Hendren Elizabeth
- Herreshoff Emily
- Hewitt Stephen
- Hidalgo Guillermo
- Hill-Callahan Peg
- Hill-Callahan Peg
- Hines William H
- Hingorani Sangeeta
- Hladunewich Michelle
- Hladunewich Michelle A
- Hogan Jonathan
- Hogan Jonathan J
- Hogan Susan
- Holzman Lawrence B
- Holzman Lawrence B
- Hooper David
- Hou Jean
- Hunley Tracy E
- Jain Amrish
- Jain Koyal
- Jain Namrata G
- Jefferson J. Ashley
- Jennette J. Charles
- Jennette J. Charles
- Jeyabalan Anushya
- Jhaveri Kenar
- Johnstone Duncan B
- Julian Bruce
- Kallash Mahmoud
- Kamel Margo
- Kaskel Frederick
- Khairallah Pascale
- Khalid Myda
- Kidd Jason
- Kil Byum Hee
- Kiryluk Krzysztof
- Kiryluk Krzysztof
- Klein Jon B
- Klein Jon B
- Kogan Amy
- Kopp Jeffrey
- Kretzler Matthias
- Kretzler Matthias
- Kump Theresa
- Lafayette Richard
- Lane Jerome C
- Lau Wai L
- Laurin Louis-Philippe
- Laurin Louis-Philippe
- Lemley Kevin V
- Liapis Helen
- Lienczewski Chrysta
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- Mansfield Sarah
- Marasa Maddalena
- Marasa Maddalena
- Mariani Laura
- Mariani Laura H
- Markowitz Glen
- Massey H. Davis
- Matar Raed Bou
- Mathews Nisha
- McCullough Keith
- Meyers Kevin
- Mohan Sumit
- Moore Nicholas
- Mottl Amy
- Mu Xueru
- Mucha Krzysztof
- Murphy Shannon
- Nachman Patrick H
- Nadasdy Tibor
- Nast Cynthia C
- Nast Cynthia C
- Nester Carla
- Neu Alicia
- Nickolas Thomas L
- Novak Jan
- O'Shaughnessy Michelle Marie
- Oliverio Andrea
- O’Toole John F
- Palmer Matthew
- Pan Cynthia
- Parekh Rulan
- Parikh Samir
- Patel Hiren
- Patterson Larry
- Pitter Renee
- Piva Stacy
- Poulton Caroline
- Poulton Caroline J
- Powell Thomas Brian
- Raad Alice
- Radhakrishnan Jai
- Rao Maya K
- Reeve Bryce
- Regunathan-Shenk Renu
- Reich Heather
- Reidy Kimberly
- Renfrow Matthew
- Revell Adelaide
- Revell Adelaide
- Reynolds Monica
- Rheault Michelle N
- Rheault Michelle N
- Rizk Dana
- Rizk Dana V
- Robinson Bruce
- Robinson Bruce M
- Rondon Helbert
- Rovin Brad
- Royal Virginie
- Saha Manish
- Sambandam Kamalanathan K
- Sampson Matthew
- Sanghani Neil
- Sanna-Cherchi Simone
- Santoriello Dominick
- Schelling Jeffrey
- Sedor John R
- Selewski David T
- Self Sally
- Sethna Christine B
- Sexton Melissa
- Shirazian Shayan
- Silva Cynthia
- Smoyer William E
- Smoyer William E
- Sperati John C
- Sreedharan Rajasree
- Srivastava Tarak
- Steinke Julia
- Stokes Michael B
- Sumner Susan
- Swiatecka-Urban Agnes
- Trachtman Howard
- Trachtman Howard
- Troost Jonathan
- Tuttle Katherine R
- Twombley Katherine
- Twombley Katherine
- Valeri Anthony M
- Vasylyeva Tetyana L
- Vento Suzanne
- Vento Suzanne
- Waldman Meryl
- Wang Chia-shi
- Weaver Donald J
- Weisstuch Joseph
- Wenderfer Scott E
- Wenderfer Scott E
- Wiggins Roger
- Winkler Cheryl
- Wladkowski Matthew
- Wong Craig S
- Yin Hong
- Young Eric
- Yu Natalie
- Zee Jarcy
- Zhdanova Olga
- Zinsser Dawn
- Zviti Ronald
- Publication venue
- Elsevier Inc
- Publication date
- 01/02/2019
- Field of study
Glomerular diseases, including minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, and immunoglobulin A (IgA) nephropathy, share clinical presentations, yet result from multiple biological mechanisms. Challenges to identifying underlying mechanisms, biomarkers, and new therapies include the rarity of each diagnosis and slow progression, often requiring decades to measure the effectiveness of interventions to prevent end-stage kidney disease (ESKD) or death.
Multicenter prospective cohort study.
Cure Glomerulonephropathy (CureGN) will enroll 2,400 children and adults with minimal change disease, focal segmental glomerulosclerosis, membranous nephropathy, or IgA nephropathy (including IgA vasculitis) and a first diagnostic kidney biopsy within 5 years. Patients with ESKD and those with secondary causes of glomerular disease are excluded.
Clinical data, including medical history, medications, family history, and patient-reported outcomes, are obtained, along with a digital archive of kidney biopsy images and blood and urine specimens at study visits aligned with clinical care 1 to 4 times per year.
Patients are followed up for changes in estimated glomerular filtration rate, disease activity, ESKD, and death and for nonrenal complications of disease and treatment, including infection, malignancy, cardiovascular, and thromboembolic events.
The study design supports multiple longitudinal analyses leveraging the diverse data domains of CureGN and its ancillary program. At 2,400 patients and an average of 2 years’ initial follow-up, CureGN has 80% power to detect an HR of 1.4 to 1.9 for proteinuria remission and a mean difference of 2.1 to 3.0mL/min/1.73m2 in estimated glomerular filtration rate per year.
Current follow-up can only detect large differences in ESKD and death outcomes.
Study infrastructure will support a broad range of scientific approaches to identify mechanistically distinct subgroups, identify accurate biomarkers of disease activity and progression, delineate disease-specific treatment targets, and inform future therapeutic trials. CureGN is expected to be among the largest prospective studies of children and adults with glomerular disease, with a broad goal to lessen disease burden and improve outcomes
Recommended from our members
Efficacy and safety of two neutralising monoclonal antibody therapies, sotrovimab and BRII-196 plus BRII-198, for adults hospitalised with COVID-19 (TICO): a randomised controlled trial
- Author
- Aagaard Bitten
- Accardi Evan
- ACTIV-3/Therapeutics for Inpatients with COVID-19 (TICO) Study Group
- Adam Stacey J
- Adams Amy
- Agarwal Trisha
- Aggarwal Neil R
- Akbari Freshta
- Albert Sara
- Alexander Elizabeth
- Almasri Eyad
- Alvarez Michael S
- Ames DeAnna
- Amos Laura
- Amosu Omowunmi
- Andreassen Helle Frost
- Applegate Darrin
- Armbruster Brent P
- Arribas Jose R
- Ashktorab Kimia
- Ashok Kiran
- Aston Valerie T
- Audette Matthew
- Babiker Abdel G
- Badhwar Vinay
- Badrock Jonathan
- Baduashvili Amiran
- Bagiella Emilia
- Baio Kim T
- Baker Jason V
- Baker Rebecca
- Bakowska Elizieta
- Balde Abby
- Banner-Goodspeed Valerie
- Bansal Aditya
- Baracco Gio
- Baracz Michelle
- Barkauskas Christina E
- Barrett Kevin
- Barros Andrew
- Bartolo Elizabeth Berry
- Baseler Beth
- Baumgarten Katherine
- Bayoumi Emad
- Beakes Caroline
- Becker Nancy
- Bednarska Agnieszka
- Bedoya Gabriela
- Bender William
- Bergsøe Christina Marisa
- Berhe Mezgebe
- Bettacchi Christopher
- Beutler Rebecca
- Bielica Mona
- Bienstock Karen
- Billouin-Frazier Shere
- Bissel Brittany
- Biswas Kousick
- Bjork Lauren
- Bledsoe Joseph
- Bojesen Ane
- Bokhart Gordon
- Bouffler Andrew
- Bowdish Michael E
- Boyle Katherine L
- Brait Kelsey
- Brar Indira
- Braun Dominique L
- Broussard Shane
- Brower Roy G
- Brown Craig
- Brown Samuel
- Brown Samuel M
- Bruun Tina
- Buck Theresa
- Bunner Robin
- Burgos Joaquin
- Burris Sarah
- Buterbaugh Sabrina
- Cabrera Gesalit
- Caccia Taylor
- Cahill Kelly
- Cao Huyen
- Carey Catherine
- Carlsen Amy
- Carter Anita
- Casey Jonathan D
- Cash Jennifer
- Cassity Evan P
- Caudill Antonina
- Chang Christina C
- Chang Steven Y
- Chauhan Lakshmi
- Chen Peter
- Chi Andrew
- Chia Po Ying
- Chiu Charlene
- Chiu Joseph
- Choe June
- Choudhary Jay
- Clapham Gregg J
- Clariday Laura
- Clausen Clara Lundetoft
- Co Ivan N
- Coleman Tanquinisha
- Cook Sharri
- Cothran Elizabeth
- Crew Page
- Crovetto Nicolle
- Currier Judy
- Davey Victoria J
- Davis Allyson
- Davis Bionca
- DellaValle Natalie
- Delp Alex
- Denning Eileen
- Der Tatyana
- Deshmukh Rupali
- DeSouza Leslie
- Dhar Sanjay
- Dillon Laura
- Ding Xiao
- Dinh Huan
- Diong Shiau Hui
- Dishner Emma
- Dixon Mary
- Dolney Suzanne
- Douglas Ivor
- Douin David J
- Dreyer Grace R
- DuChateau Nadine
- DuChene Alain
- Duggal Abhijit
- Duhaime Erin
- Duque Krizia
- Eichinger Mareile L
- Eichman Sharon M
- Enfield Kyle B
- Engen Nicole
- Escobar Jose
- Esmann Frederik V.L
- Estrada Vicente
- Evans Raquel
- Exposito Maria
- Eyler Carolyn
- Fabricius Thilde
- Fayed Mohamed
- Fenton Kathleen
- Fergus Melissa
- Fernández-Cruz Eduardo
- Fielding Michele
- Filbin Michael R
- Files D. Clark
- Finck Lani L
- Fisher Tammy
- Fitzgerald Laura
- Fleischmann Emily
- Flores Lori S
- Flosi Adam
- Fornaresio Lisa
- Fox Ashley
- Franzone John
- Freasier Heather
- Fresnedo Michelle
- Frosch Anne
- Frye Leanna
- Fätkenheuer Gerd
- Galbraith James
- Galcik Michael
- Gammie James S
- Garcia Rebekah L
- Garcia-Myers Kelly
- Gardner Edward M
- Gee Adrienne
- Gelijns Annetine C
- Germann Heather H
- Gerry Norman P
- Gerstoft Jan
- Gertz Jensen
- Giangiacomo Dana M
- Gibbs Keven W
- Giebeig Lisa
- Gillinov Marc A
- Ginde Adit A
- Gioukari Vicky
- Girardet Jean-Luc
- Glaze Chad
- Golden Kevin
- Goldsmith Rachael
- Gong Michelle N
- Gonzales Sonia
- Goodman Anna
- Gottlieb Robert L
- Grandits Greg
- Gray Christopher
- Green China J
- Gregory Adam
- Grevsen Anne Louise
- Grube Christina
- Grund Birgit
- Grüttner-Durmaz Manuela
- Gulati Neelam
- Gupta Lopa
- Gupta Rajesh
- Günthard Huldrych F
- Haley Clinton
- Haley Elizabeth
- Hand Jonathan
- Hankinson Liz
- Hanna Sinan
- Hansen Laura
- Hansen Thomas Michael
- Harrington Cristin
- Harris Nicola
- Harrison Merrie
- Haukoos Jason
- Havmøller Signe Ravn
- Hayanga J. Awori
- Hayes Sharon
- Hays Margaret
- Helleberg Marie
- Hendershot Jennifer
- Hendey Gregory
- Hensley Lisa
- Hernandez Nilmo
- Herpin Betsey R
- Herrera Lisa
- Herring Karen
- Hertz Mathias A
- Hibbert Kathryn A
- Higgs Elizabeth S
- Hindoyan Niree A
- Hines-Munson Casey
- Hissey Debbie
- Hite R. Duncan
- Hogarty Debi
- Hohn Matt
- Holland Thomas L
- Holley H Preston
- Hollister Beth A
- Hong Zhi
- Hoopengardner Lisa
- Hoover Marie L
- Horban Andrzej
- Horcajada Juan P
- Hou Peter
- Hough Catherine L
- Hough Sally
- Hovmand Nichlas
- Howell Michelle
- Hubel Kinsley A
- Huber Lynda
- Hudock Kristin
- Hudson Fleur
- Hughes Alyssa R
- Hughes Eric
- Hurutado-Rodriguez Marian
- Hutcheon Douglass
- Hyzy Robert C
- Høgsberg Dorthe S
- Imel Karah
- Iram Nazia
- Iribarne Alexander
- Isaac Geralyn
- Jackman Susan E
- Jain Mamta K
- Jankelevich Shirley
- Jauregui Alejandra E
- Jensen Jens-Ulrik
- Jensen Tomas O
- Jensen Tomas Østergaard
- Jerrow Janet
- Jia Shijing
- Jibrell Hodan
- Joensen Zillah Maria
- Johansen Isik S
- Johnsen Stine
- Johnson Haley
- Johnson Jakea
- Johnson Les
- Jones Alan E
- Jones Felecia
- Jundgren Jens D
- Jurek Natalia
- Justino Chris
- Kadl Alexandra
- Kaiser Payton
- Kalan Shivam P
- Kamel Dena
- Kamis Kevin
- Kamstrup Thobias
- Kan Virginia
- Kangelaris Kirsten N
- Kanne Katja Lisa
- Kardos Cynthia
- Kelleher Anthony
- Kennedy Sarah
- Khan Akram
- Killian Aaron
- King Alexander H
- Kinjal Mistry
- Kinzel Emily
- Kiran Simra
- Kirchoff Matthew
- Kityo Cissy M
- Kiweewa Francis
- Klaphake Jonathan
- Knowlton Kirk U
- Knudsen Lene Surland
- Knudtzen Fredrikke C
- Ko Emily R
- Koopmeiners Joseph
- Kowalska Justyna
- Kozikowski Lori-Ann
- Krapp Katharina
- Krauss Gary
- Krol Olivia F
- Krupica Troy
- Kubernac Amanda
- Kubernac Robert
- Kumar Naresh
- Kumar Princy
- Lake Eileen
- Landreth Leigha D
- Lane H. Clifford
- Lane Kathleen
- Lanspa Michael
- LaRose Mary E
- Larsen Lykke
- Lau Christine
- Laudun Sylvia
- Lee Maia
- Lee May M
- Lee Myounghee
- Lee Tau Hong
- Leither Lindsey
- Leonard Kiara
- Leong Janet
- Leshnower Bradley G
- Levine Andrea
- Lewis Meghan R
- Lichtenberger Paola
- Lim George W
- Lin Leo
- Lin Ray J
- Lindegaard Birgitte
- Lindnér Cecilia Ebba Clara Ellinor
- Linton Jessica
- Lo Melanie
- Lopez Brenda
- Lorenzo Josua
- Lozano Edward
- Lucas Claudia Sanchez
- Lusk Erica
- Lutaakome Joseph
- Lye David
- Løfberg Sandra Valborg
- M'Rabeth-Bensalah Khadija
- Ma Ji
- MacDonald Leah
- Mack Michael
- Mackedanz Shari
- Madathil Ronson J
- Malinm Jakob J
- Manandhar Meryan
- Margolin Justin D
- Margolis David
- Markowitz Norman
- Marks Mary E
- Maroney Karen
- Martinkovic Jamie
- Mathewson Sonya
- Maton Missy
- Matthay Michael A
- Matthews Gail
- Matusov Yuri
- Mayer Kirby P
- McBride Mary K
- McCarthy Paul
- McDaniel Hunter
- McDougal Madeline
- McGowan Lauren M
- McKernan Kimberley
- McLean Sherry
- McLendon-Arvik Beth
- McNay Laura A
- McSparron Jake I
- Meger Sue
- Mehdikhani Shaunt
- Mehkri Omar
- Menna Maximiliano
- Metzler Sara
- Mikail Amani
- Miller Chadwick
- Miller Jeffrey
- Miller Leslie
- Miller Marissa A
- Mills Emmanuel
- Mock Rebecca
- Mogalian Erik
- Montgomery Quinn
- Montgomery-Yates Ashley A
- Moore Jessica
- Moquete Ellen
- Morales-Rull Jose Luis
- More Harshada
- Morin Haley D
- Morris Peter E
- Morse Richard
- Mosaly Nilima
- Mosier Jarrod M
- Moskowitz Alan J
- Moss Marc
- Motta Marry
- Mourad Ahmad
- Mugerwa Henry
- Murphy Joseph
- Murrary Daniel D
- Murray Thomas
- Muzikansky Ariela
- Muñoz José
- Nagy-Agren Stephanie
- Nair Rahul
- Nandi Utsav
- Neaton James D
- Nekach Hafida
- Nelson Kristine
- Newton Crystallee
- Ngo Linh
- Nguyen Chinh
- Nguyen Phuong Tran
- Nielsen Ariella Denize
- Nielsen Charlotte B
- Nielsen Henrik
- Normand Nick E
- North Crystal
- Nossaman Bobby
- Nyatsatsang Sonam T
- Nykjær Bente Rosdahl
- Nytofte Nikolaj Julian Skrøder
- O'Mahony D. Shane
- O'Sullivan Karen
- Ochalek Tracy
- Offor Obiageli
- Ojukwu Cristabelle
- Olbrich Norman
- Oldmixon Cathryn
- Olds Anna P
- Oluremi Charles
- Ong Sean
- Ongko Juwinda
- Osei Suzette
- Osinusi Anu
- Overbey Jessica R
- Padillia Maria L
- Palacious Adriana
- Palmer Ghazal
- Pandit Lavannya
- Pantaz Nikos
- Pappers Brian
- Paredes Roger
- Pariser Alan
- Park Pauline K
- Parmar Mahesh KB
- Parr Doug
- Parrino Patrick E
- Parry Blair Alden
- Pascual Ethan
- Pasha Sara N
- Pastor Erika
- Patel Bhakti
- Paul Pam
- Peacock Rebekah K
- Pedersen Karen Brorup
- Pedersen Lars
- Pedersen Thomas Ingemann
- Peguero Maya-Loren
- Peltan Ithan D
- Peppercorn Amanda
- Perez Cynthia
- Petersen Tianna
- Pett Sarah
- Podlekareva Daria
- Polizzotto Mark N
- Ponder Chari
- Popielski Laura
- Porte Kristina
- Possemato Tammie
- Preamble Katarina
- Proffitt Calvin
- Puah Ser Hon
- Quan Kien
- Quan Siu Fun
- Raben Dorthe
- Rabin Joseph
- Raim Sharon Segal
- Ramesh Mayur
- Ramierez Noelia
- Ramos Carol
- Ransom Desirae
- Rashid Marium
- Rastoder Ema
- Read Sarah
- Reece Rebecca
- Reilly Cavan S
- Reineck Lora A
- Rice Todd W
- Richardson Lynne D
- Ringwood Nancy
- Rivasplata Heather
- Rivers Emanuel
- Roads Tammy
- Robert Raven
- Robinson Bryce H
- Robinson Caitlin
- Robinson Dianna
- Rodina Valentina
- Rodriguez Vicente
- Rogers Angela J
- Rogers Susan
- Roller Brentin
- Romero Chris
- Roque Jonasel
- Roth Megan
- Rothbaum Howard R
- Rudzinski Erin
- Ryan Madison
- Røge Birgit Thorup
- Saharia Kapil
- Salehi Hanna
- Sandkovsky Uriel
- Sandrus Jen
- Santos Milerva
- Sardana Ratna
- Sarwari Arif
- Schaffhauser Marylu
- Schechner Adam
- Schelle Beth
- Scott James
- Self Wesley H
- Serezlic Erna
- Shapiro Nathan
- Sharifpour Milad
- Sharma Aniket
- Sharma Shweta
- Sharma Sunil
- Shaw-Saliba Katy
- Sher Linda
- Shipman Samantha
- Simon Rachel M
- Smith Kenneth
- Smith Peter K
- Smolskis Mary C
- Solis Edilia
- Solomon Courtney
- Spainhour Christine
- Spellberg Brad
- Spindel Stephen
- Spinelli-Nadzam Mary
- Stallings Ben
- Steingrub Jay
- Stout Gennifer
- Sturek Jeffrey M
- Sturgill Jamie L
- Stærke Nina Breinholt
- Suders Connie
- Sueiro Melyssa
- Sullins Barbara
- Sutton Lisa Giblin
- Sánchez Adriana
- Tabatabai Ali
- Taddei-Peters Wendy C
- Talmor Daniel
- Terndrup Thomas E
- Thammavong Jon
- Thiruchelvam Nirosshan
- Thisted Rikke Krog
- Thompson B. Taylor
- Thompson Greg
- Thorlacius-Ussing Louise
- Thornton Kara
- Thornton-Thompson Sherell
- Tidswell Mark A
- Tien Phyllis
- Tierney John
- Tinggaard Michaela
- Tipple Craig
- Tipton Gregory
- Torbati Sam S
- Touloumi Giota
- Towfighi Amytis
- Tran Sonny
- Trautner Barbara W
- Treagus Amy
- Turner Emma
- Turner Melissa
- Tyler Derrick
- Tzehaie Hiwet
- Van John
- Vargas Julia
- Vasudeva Shikha
- Vekstein Andrew
- Villa Samantha
- Vincent Shelika
- Virachit Sophie
- Vjecha Michael
- Vock David M
- Voge Susan E
- Vojnik Rosemary
- von Huth Sebastian Leicht
- Vonderhaar Derek
- Wald-Dickler Noah
- Wallick Julie A
- Walski Jamie
- Wang Bonnie R
- Want Samantha
- Want Yiqun
- Watson Helen
- Watts Matthew
- Webb Brandon
- Weintrob Amy C
- Weissman Kevin
- Wenner Christine
- Wentworth Deborah
- West Emily
- Whitacre Heather
- Wiedemann Herbert P
- Wiese Lothar
- Williams Roger
- Willis Angela
- Wilson David M
- Wilson Jennifer G
- Witte Marie
- Woldbye Frederik
- Wyles David
- Wynter Timothy
- Yan Li
- Yee Kimberly J
- Yeo Tsin Wen
- Young Barnaby E
- Zheng Yiling
- Zhong Amy
- Zhu Qing
- Zhuo Hanjing
- Zink Veronika
- Zuckerman Judith
- Zuckerman Richard A
- Østergaard Lars
- Publication venue
- Elsevier Ltd
- Publication date
- 01/05/2022
- Field of study
We aimed to assess the efficacy and safety of two neutralising monoclonal antibody therapies (sotrovimab [Vir Biotechnology and GlaxoSmithKline] and BRII-196 plus BRII-198 [Brii Biosciences]) for adults admitted to hospital for COVID-19 (hereafter referred to as hospitalised) with COVID-19.
In this multinational, double-blind, randomised, placebo-controlled, clinical trial (Therapeutics for Inpatients with COVID-19 [TICO]), adults (aged ≥18 years) hospitalised with COVID-19 at 43 hospitals in the USA, Denmark, Switzerland, and Poland were recruited. Patients were eligible if they had laboratory-confirmed SARS-CoV-2 infection and COVID-19 symptoms for up to 12 days. Using a web-based application, participants were randomly assigned (2:1:2:1), stratified by trial site pharmacy, to sotrovimab 500 mg, matching placebo for sotrovimab, BRII-196 1000 mg plus BRII-198 1000 mg, or matching placebo for BRII-196 plus BRII-198, in addition to standard of care. Each study product was administered as a single dose given intravenously over 60 min. The concurrent placebo groups were pooled for analyses. The primary outcome was time to sustained clinical recovery, defined as discharge from the hospital to home and remaining at home for 14 consecutive days, up to day 90 after randomisation. Interim futility analyses were based on two seven-category ordinal outcome scales on day 5 that measured pulmonary status and extrapulmonary complications of COVID-19. The safety outcome was a composite of death, serious adverse events, incident organ failure, and serious coinfection up to day 90 after randomisation. Efficacy and safety outcomes were assessed in the modified intention-to-treat population, defined as all patients randomly assigned to treatment who started the study infusion. This study is registered with ClinicalTrials.gov, NCT04501978.
Between Dec 16, 2020, and March 1, 2021, 546 patients were enrolled and randomly assigned to sotrovimab (n=184), BRII-196 plus BRII-198 (n=183), or placebo (n=179), of whom 536 received part or all of their assigned study drug (sotrovimab n=182, BRII-196 plus BRII-198 n=176, or placebo n=178; median age of 60 years [IQR 50–72], 228 [43%] patients were female and 308 [57%] were male). At this point, enrolment was halted on the basis of the interim futility analysis. At day 5, neither the sotrovimab group nor the BRII-196 plus BRII-198 group had significantly higher odds of more favourable outcomes than the placebo group on either the pulmonary scale (adjusted odds ratio sotrovimab 1·07 [95% CI 0·74–1·56]; BRII-196 plus BRII-198 0·98 [95% CI 0·67–1·43]) or the pulmonary-plus complications scale (sotrovimab 1·08 [0·74–1·58]; BRII-196 plus BRII-198 1·00 [0·68–1·46]). By day 90, sustained clinical recovery was seen in 151 (85%) patients in the placebo group compared with 160 (88%) in the sotrovimab group (adjusted rate ratio 1·12 [95% CI 0·91–1·37]) and 155 (88%) in the BRII-196 plus BRII-198 group (1·08 [0·88–1·32]). The composite safety outcome up to day 90 was met by 48 (27%) patients in the placebo group, 42 (23%) in the sotrovimab group, and 45 (26%) in the BRII-196 plus BRII-198 group. 13 (7%) patients in the placebo group, 14 (8%) in the sotrovimab group, and 15 (9%) in the BRII-196 plus BRII-198 group died up to day 90.
Neither sotrovimab nor BRII-196 plus BRII-198 showed efficacy for improving clinical outcomes among adults hospitalised with COVID-19.
US National Institutes of Health and Operation Warp Spee
Recommended from our members
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two: National Harbor, MD, USA. 9-13 November 2016
- Author
- Abassi Yama
- Abelin Jennifer G.
- Abolhalaj Milad
- Abraham Tara S.
- Adam Ammar
- Adams David
- Adams Homer
- Adams Sarah F.
- Adamus Tomasz
- Addepalli Murali
- Adjei Alex A.
- Agapova Larissa
- Agarwala Sanjiv
- Ager Casey
- Aggarwal Charu
- Agnello Giulia
- Agudo Judith
- Aguilar Ethan G.
- Aguilera Todd
- Ahamadi Malidi
- Ahn Yong-Oon
- Ahrens Eric T.
- Aizer Ayal
- Ajina Reham
- Akerley Wallace
- Al-Muftah Mariam
- Albershardt Tina C.
- Albrekt Ann-Sofie
- Alekar Shilpa
- Alemany Ramon
- Alexander Brian
- Allbritton Omaira
- Allen Clint T.
- Alley Evan W.
- Allison James
- Alston Tesha
- Alt Jürgen
- Alters Susan
- Amatulli Michael
- Anand Snjezana
- Anderson Clark
- Anderson Mark
- Andersson Bengt
- Andre Pascale
- Andtbacka Robert H. I.
- Angiuoli Sam
- Ansari Tameem
- Anthony Scott
- Antonarakis Emmanuel S.
- Antonia Scott J.
- Anwar Firoz
- Aquino-Michaels Keston
- Archer Jacob F.
- Arina Ainhoa
- Armand Philippe
- Armenta Paul
- Armet Caroline M.
- Arnoux Thomas
- Ascarateil Stephane
- Askmyr David
- Atkins Michael
- Atkins Michael B.
- Atkinson Victoria
- Au Katrina
- Autio Karen A.
- Awad Mark
- Bagarazzi Mark
- Bai Dina
- Baia Gilson
- Baird Jason
- Bajaj Anshika
- Balatoni Timea
- Balboni Tracy
- Balch Leslie
- Bang Andrew
- Bao Riyue
- Bao Yangyi
- Barakat David
- Barberi Theresa
- Barker Christopher A.
- Barnea Eytan
- Barras David
- Bartkowiak Todd
- Bartlett David
- Barton Sunjay M.
- Barve Minal
- Bauer Todd
- Bauer Todd W.
- Bauman Julie
- Baumgaertner Petra
- Bauml Joshua
- Beceren-Braun Figen
- Beck Kristen
- Becker Annette
- Beckers Johannes
- Beckett Michael A.
- Bedognetti Davide
- Bell Bryan
- Bell Charles J. M.
- Bell Peter
- Beltran Pedro
- Bender Lewis H.
- Bender Steven
- Bennett Mark K.
- Benz Steven
- Bera Tapan
- Berglund Peter
- Berkey Sara
- Bernatchez Chantale
- Berry John S.
- Berzofsky Jay A.
- Bhardwaj Nina
- Bian Zhen
- Bianco Alberto
- Biediger Ronald J.
- Bifulco Carlo
- Bigley Alison
- Bingham Patrick
- Biniszkiewicz Detlev M.
- Bischoff Helge
- Blake Zoe
- Blakely Collin
- Blazar Bruce R.
- Blogowski Wojciech
- Bloom Anja C.
- Boehm Jesse
- Bokovanov Vladimir
- Bommareddy Praveen K.
- Booth Jamie
- Bornschlegl Svetlana
- Bose Nandita
- Bossenmaier Birgit
- Boughorbel Sabri
- Boyer Jean
- Bramante Simona
- Branstetter Daniel
- Brech Dorothee
- Brenin David
- Broaddus V. Courtney
- Brockstedt Dirk G.
- Brody Joshua
- Bronson Roderick
- Brooks Alan
- Brooks Alan D.
- Broucek Joseph
- Brown Alice
- Brown Brian
- Brown Brittany
- Brown Gail L.
- Brown Sheila
- Bruce Jeffrey N.
- Brunet Laura Rosa
- Bruno Tullia C.
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- Bryant Richard
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- Cao Felicia
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- Caplazi Patrick
- Cappuccini Federica
- Carcaboso Angel M.
- Carlino Matteo S.
- Carpi Sara
- Carrasco Ruben
- Carrera Diego A.
- Carrero Rosa M. Santana
- Carson Dennis A.
- Castellini Laura
- Cathomas Richard
- Cauvin Annick
- Cauwenberghs Sandra
- Caux Christophe
- Cebon Jonathan S.
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- Celis Esteban
- Cerignoli Fabio
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- Cesareni Gianni
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- Chan Ivan
- Chan Leo
- Chan Timothy A.
- Chang Alfred E.
- Chang Joe
- Chang Nancy N.
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- Chanuc Fabien
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- Chappel Scott C.
- Charych Deborah H.
- Chaudhuri Amitabha
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- Chiang Eugene
- Chikina Maria
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- Terabe Masaki
- Termini James
- Tetzlaff Michael
- Tewary Poonam
- Thakurta Anjan
- Thayer Matt
- Theodoraki Marie-Nicole
- Thimme Robert
- Thomas Portia
- Thomas Remy
- Thomas Vincent
- Thompson John A.
- Thounaojam Menaka
- Thurston Gavin
- Tighe Rober
- Tilahun Ashenafi
- Tillé Laure
- Timmerman John
- Tipton Kimberly A.
- Tognon Christina E.
- Tomai Mark A.
- Toms Anne
- Torno Sebold
- Torrey Heather
- Torti Vince
- Toth Laszlo
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- Trivedi Sumita
- Truesdell Peter
- Tsang Kwong
- Tsang Kwong Y.
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- Tsouko Efrosini
- Tsujikawa Takahiro
- Tuck David
- Tumang Joseph
- Turbitt William J.
- Turk Andrew T.
- Tyner Jeffery W.
- Tähtinen Siri
- Uecker Darrin
- Ugel Stefano
- Uhlik Mark
- Ujhelyi Mihaly
- Ullenhag Gustav
- Unfricht Darryn
- Ungerleider Richard
- Urban Julie
- Valsesia-Wittmann Sandrine
- Van der Meijs Pien
- van Vugt Marianne
- van Zutphen Mariëlle
- Vanamee Eva
- Vanderslice Peter
- VanderVeen Laurie
- Vanpouille-Box Claire I.
- VanVlasselaer Peter
- Varhegyi Nikole
- Vasilakos John P.
- Vaske Charles
- Vassilev Lotta
- Velcheti Vamsidhar
- Velculescu Victor
- Verma Amita
- Vetto John
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- Vietsch Eveline E.
- Vignali Dario
- Vogel Katharina
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- vonEbyen Rie
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- Vu Tuyen
- Wada Hiroshi
- Wagtmann Nicolai
- Waldman Michelle
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- Waller John
- Wallraven Gladice
- Walsh Richard
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- Wang Ena
- Wang Hongjie
- Wang Ping
- Wang Shangzi
- Wang Weiyi
- Wang Ximi K.
- Wang Yi
- Wang Ziming
- Ward Stephen T.
- Waugh Katherine
- Weber Amy
- Wehler Thomas
- Wei Spencer
- Weichselbaum Ralph R.
- Weiner David
- Weiner Louis M.
- Weinstein Gregory
- Weiss Christian
- Welden Scott
- Wellstein Anton
- Welsh James
- Wennerberg Erik
- Wenthe Jessica
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- West Brian
- West James
- Wheatley Courtney
- Whetstone Ryan
- White James
- White-Stern Ashley
- Whiteside Melinda
- Whiting Chan C.
- Wicha Max S.
- Wieckowski Eva
- Wijeratne Kithsiri
- Wilhite Tyler
- Wilkinson Robert W.
- Williams Matthew
- Williamson Kevin
- Willingham Stephen
- Wilson James M.
- Wilson Nicholas
- Winters Kevin
- Withers Sita
- Wittig Burghardt
- Wolchok Jedd D.
- Wolfreys Alison
- Won Haejung
- Wong Chihunt
- Wong Deborah J.
- Wong Gabriel
- Wong Kenneth R.
- Wong Michael KK
- Wood Laura
- Woodside Darren G.
- Workman Creg
- Wu Bill X.
- Wu Dongyun
- Wu Jennifer
- Wu Yeting
- Wyant Timothy
- Wythes Martin
- Xi Biao
- Xia Leiming
- Xia Yang
- Xiang Bo
- Xiao Christine
- Xiao Hong
- Xiao Zhilan
- Xu Chun-wei
- Xu Chunxiao
- Xu Guifen
- Xu Xiaomei
- Xu Xin
- Xu Ya-Ming
- Xu Yitong
- Yadav Mahesh
- Yagiz Kader
- Yamashiro Darrell J.
- Yan Jian
- Yang Chou
- Yang Ning
- Yang Zane
- Yano Hiroshi
- Yao Shiyin
- Ye Yun-bin
- Yin Catherine
- Ylösmäki Erkko
- Young Gregory
- Young Kristina
- Young Rob
- Young Steve W.
- Youssoufian Hagop
- Yu Huakui
- Yu Ling
- Yu Naichen
- Zafar Sadia
- Zalevsky Jonathan
- Zappasodi Roberta
- Zauderer Maurice
- Zeh Herbert
- Zelenetz Andrew D.
- Zeng Weiping
- Zeng Xue
- Zha Yuanyuan
- Zhang Danhui
- Zhang Jing
- Zhang Ping
- Zhang Qifang
- Zhang Shannon S.
- Zhang Theresa
- Zhang Winter
- Zhang Yanping
- Zhao Fei
- Zhao Leyna
- Zhao Xingli
- Zheng Lianxing
- Zheng Wenxin
- Zheng Xianxian
- Zheng Yi
- Zhong Hong
- Zhou Li
- Zhou Xiangjun
- Zippelius Alfred
- Zloza Andrew
- Zou Jun
- Zuba-Surma Ewa
- Zubkova Olga
- Zureikat Amer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 03/01/2017
- Field of study
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- Arlington County Public Schools
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- Asian American Student Alliance Quarry
- Asian Pacific Labor
- Asian Pacific PlanningCouncil
- Asian ResourceCenter
- Asian Women United of California. Muking Waves:An Anthologyof WritingsByand About Asian American Women.Boston
- AsianPacificAmericanLegal Center
- Asselle Maria Grazia
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- Atfunta Source
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- Chien Cynthia
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- Christensen Carole Pigler
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- Haldane David
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- Hirabayashi
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- Holtan Neal
- Houghton D.S.
- Hoy Ronald R
- Hromadiuk Bob
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- Hsia Y. E.
- Hsu Jsing
- Hu Arthur
- Hua Chuang
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- Huntington Cynthia
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- Ichioka Yuji
- Immigrant Women
- Immigration Canada
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- Irons Peter
- Ishi Tomoji
- Israel Milton
- Iwata Edward
- Jabbra W.
- Jackson O.
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- Katayama Mary
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- Kikumura Akemi
- Kim
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- Kim Kwang Chun
- Kim Y. Y.
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- Nevada University
- New York State Education Department
- Ng Johnny
- Ng R O X
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- ResearchGroup on theLos An les Economy.
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- Rex
- Rice Richard B
- Rick Simonsen
- Riddle Tom
- Risen James
- Ritchie Joan E
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- River Massachusetts
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- Social Science
- Sociology
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- Song Cathy
- Soto Gary
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- Speraw S.
- Spoehr Alexander
- Sridhar Kamal K
- Stabile Jeff
- Staccy Jackie
- Stasiulus Daiva
- Steltzer Ulli
- Stem TWM
- Stenderup Viberke
- Stephan Cookie White
- Stokes Bruce
- Stolarik M. Mark
- Strnfa
- Strom Robert
- Stromquist Shelton
- Strouse Joan
- Studies Center
- Subramani
- Sue JenniferAbe
- Summers Molly
- Sunoo Brenda Paik
- Tabrah Ruth M
- Tainer Evelina
- Takagi Mariko
- Takaki JanieHitomi
- Takaki Ronald
- Takami David
- Takami David
- Tamura Linda
- Tan Amy
- Tarpley John
- Tatar Elizabeth
- Taverna Odette
- Teachers College
- Tepper M.
- The
- The Original Tracks Portland
- Thompson Richard H
- Tidwell Romeria
- Tien-Hyatt L.
- Tiffany Sharon W
- Tinloy Marion
- Tokyo
- Tollefson W.
- Tong Rosemarie
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- Tsui P.
- Tsukada Mamoru
- Tsutakawa Mayumi
- Tumarkin D. D.
- U.S. Commission
- Uamzon T. A.
- Ugalde-Yellen Corazon
- Umemoto Karen
- Unnithan N. Prabha.
- Urban Education
- Van Tran Thahn
- Vang Chue
- Vang Kou
- Vang Kou
- Vaughan Palani
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- White Hmong Language Lessons
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- Wong Bernard
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- Wong-Rieger Durhane
- Woo Merle
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- Wurzel Jaime
- Xenos Peter
- Yamamoto Hisaye
- Yamamoto Joe
- Yamamoto Kathee
- Yao Esther Lee
- Yao Mary V
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- Yee L. Y.
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- Yochum Gilbert
- Yoon K. K.
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- Publication venue
- 'UCLA American Indian Studies Center'
- Publication date
- Field of study