1,753 research outputs found

    Monitoring of Cell Layer Integrity with a Current-Driven Organic Electrochemical Transistor

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    The integrity of CaCo-2 cell barriers is investigated by organic electrochemical transistors (OECTs) in a current-driven configuration. Ion transport through cellular barriers via the paracellular pathway is modulated by tight junctions between adjacent cells. Rupturing its integrity by H2O2 is monitored by the change of the output voltage in the transfer characteristics. It is demonstrated that by operating the OECT in a current-driven configuration, the sensitive and temporal resolution for monitoring the cell barrier integrity is strongly enhanced as compared to the OECT transient response measurement. As a result, current-driven OECTs are useful tools to assess dynamic and critical changes in tight junctions, relevant for clinical applications as drug targeting and screening

    Extenzív szántók gyomcönológiai vizsgálata Észak-nyugat Dunántúlon = Phytosociological survey of weed communities on extensive fields in North-western Hungary

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    A Dunántúli-középhegység és a Nyugat-Magyarországi peremvidék extenzív vetéseiben a következő vegetációtípusok leírására került sor: Nyári aszpektusban bázikus-meszes vályogos talajon a Camelino-Anthemidetum caucalietosum; semleges talajon (vagy a nagyobb mérvű intenzifikációval) a Camelino-Anthemidetum typicum, savanyú talajon pedig a Camelino-Anthemidetum scleranthetosum. Ezeket a típusokat, bázikus homokon a Sisymbrio-Anthemidetum, míg savanyú homokon a Spergulo-Anthemidetum váltja fel. A szubatlantikus klíma befolyása alatt savanyú vályog- és agyagtalajokon az Aphano-Matricarietum scleranthetosum uralkodik. A Capsello-Descurainietum a növekvő intenzifikációval alakul ki a Camelino-Anthemidetum termőhelyén. A Camelino-Anthemidetum-ot őszi aszpektusban a tarlókon a Stachyo-Setarietum váltja fel, míg az Aphano-Matricarietum termőhelyén a Chenopodio-Oxalidetum a jellemző tarlószövetkezet. A kapáskultúrákban az egész vizsgált területen, bár sokszor csak nagyon elszegényedett formában az Echinochloo-Setarietum terjedt el. | In the surveyed area the following vegetation units have been distinguished: Camelino-Anthemidetum caucalidetosum as summer-association on loamy calcareous soils, Camelino-Anthemidetum typicum on neutral soils (or by larger intensification), Camelino-Anthemidetum scleranthetosum on acidic soils. These units are substituted by Sisymbrio-Anthemidetum on basic sand, while by Spergulo-Anthemidetum on acidic sand. Under the effect of Submediterranean climate Aphano-Matricarietum scleranthetosum on acidic loam and clay prevails. Capsello-Descurainietum evolves with increasing intensification in habitat of Camelino-Anthemidetum. Camelino-Anthemidetum is substituted by Stachyo-Setarietum as autumn-association on stubble fields while in the habitat of Aphano-Matricarietum, Chenopodio-Oxalidetum is the typical stubble community. In row crop fields Echinochloo-Setarietum is the most frequent association

    Connect vs. conquer? CEO gender and implicit motives

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    This is the author accepted manuscript. The final version is available from Emerald via the DOI in this recordPurpose – This study examined gender differences in CEOs’ expression of implicit achievement, power, and affiliation motivation. Building on the role congruity account of sex differences and similarities in motivation and existing literature on implicit motives, the study tested whether female CEOs would express higher affiliation motivation than male CEOs and similar levels of achievement motivation. In addition, gender differences in power motivation were explored. Design/methodology/approach – The study used propensity score matching to generate a comparable sample of male and female CEOs from publicly-traded companies. Subsequently, the authors content-coded CEO letters from annual reports using Winter’s (1994) manual for scoring motive imagery in running text. Findings – Overall, CEOs expressed more achievement and power motivation than affiliation motivation. Comparisons between male and female CEOs showed that female CEOs expressed lower power and higher affiliation motivation than male CEOs. Research limitations/implications – By integrating implicit motive theory with social role theory and the role congruity account of motivation, this study provides a theoretical framework and novel demonstration that understanding social roles and gender roles can lend insights into motive expression by CEOs. Originality/value – The study uses established theory and a validated scoring method in a novel way by analyzing implicit motives from CEO letters, a critical communication channel in the CEO-shareholder relationship. In doing so, this study adopts a socio-cultural perspective. Informed by the role congruity account of motivation, the study demonstrates the importance of social roles and gender roles for motivational displays

    Measurement of the Omega_c Lifetime

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    We present the measurement of the lifetime of the Omega_c we have performed using three independent data samples from two different decay modes. Using a Sigma- beam of 340 GeV/c we have obtained clean signals for the Omega_c decaying into Xi- K- pi+ pi+ and Omega- pi+ pi- pi+, avoiding topological cuts normally used in charm analysis. The short but measurable lifetime of the Omega_c is demonstrated by a clear enhancement of the signals at short but finite decay lengths. Using a continuous maximum likelihood method we determined the lifetime to be tau(Omega_c) = 55 +13-11(stat) +18-23(syst) fs. This makes the Omega_c the shortest living weakly decaying particle observed so far. The short value of the lifetime confirms the predicted pattern of the charmed baryon lifetimes and demonstrates that the strong interaction plays a vital role in the lifetimes of charmed hadrons.Comment: 15 pages, including 7 figures; gzipped, uuencoded postscrip

    Coulomb corrections to low energy antiproton annihilation cross sections on protons and nuclei

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    We calculate, in a systematic way, the enhancement effect on antiproton-proton and antiproton-nucleus annihilation cross sections at low energy due to the initial state electrostatic interaction between the projectile and the target nucleus. This calculation is aimed at future comparisons between antineutron and antiproton annihilation rates on different targets, for the extraction of pure isospin channels.Comment: 18 pages, 4 figures (latex format

    Nuclei, Superheavy Nuclei and Hypermatter in a chiral SU(3)-Modell

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    A model based on chiral SU(3)-symmetry in nonlinear realisation is used for the investigation of nuclei, superheavy nuclei, hypernuclei and multistrange nuclear objects (so called MEMOs). The model works very well in the case of nuclei and hypernuclei with one Lambda-particle and rules out MEMOs. Basic observables which are known for nuclei and hypernuclei are reproduced satisfactorily. The model predicts Z=120 and N=172, 184 and 198 as the next shell closures in the region of superheavy nuclei. The calculations have been performed in self-consistent relativistic mean field approximation assuming spherical symmetry. The parameters were adapted to known nuclei.Comment: 19 pages, 11 figure
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