1,355 research outputs found
The distribution and taxonomy of Lissotriton newts in Turkey (Amphibia, Salamandridae)
Two and perhaps three taxa of
Lissotriton
newt occur in Turkey. Their species status is controversial. The
distribution of these taxa and the taxonomic status of each are reviewed and discussed. A database of 128
Turkish
Lissotriton
localities was compiled and species distribution models were constructed. We reiterate
that the presence of
L.
(
v.
)
lantzi
in Turkey is disputed and needs confirmation. The range of
L.
(
v.
)
koss
-
wigi
is restricted to north-western Anatolia – given the small global range of this Turkey endemic, a closer
look at its conservation status is warranted. The distribution of
L. v. schmidtleri
covers western Asiatic
and European Turkey. The findings support an allopatric distribution of the Turkish
Lissotriton
species.
We reflect on the biological significance of previously reported morphological intermediates between
L.
(
v.
)
kosswigi
and
L. v. schmidtleri
in the light of the recent proposal to recognize
kosswigi
at the species
level. The available data are in line with species status for
L.
(
v.
)
lantzi
and
L.
(
v.
)
kosswigi
. Although
L. v.
schmidtleri
is a genetically diverged taxon as well, the extent of gene flow with parapatric European
Lis
-
sotriton
taxa is as yet unknown
PCV45 Long Term Cost-Effectiveness Analysis of Ticagrelor in Patients with Acute Coronary Syndromes From a Turkish Health Care Perspective Based on Data From the Plato Trial
Theory and analysis of electrode size optimization for capacitive microfabricated ultrasonic transducers
Cataloged from PDF version of article.Theoretical analysis and computer simulations of capacitive microfabricated ultrasonic transducers indicate that device performance can be optimized through judicious patterning of electrodes. The conceptual basis of the analysis is that electrostatic force should be applied only where it is most effective, such as at the center of a circular membrane. If breakdown mechanisms are ignored, an infinitesimally small electrode with an infinite bias voltage results in the optimal transducer, A more realistic design example compares the 3-dB bandwidths of a fully metalized transducer and a partially metalized transducer, each tuned with a lossless Butterworth network. It is found that the bandwidth of the optimally metalized device is twice that of the fully metalized device
Isovector Collective Response Function of Nuclear Matter at Finite Temperature
We study isovector collective excitations in nuclear matter by employing the
linearized Landau-Vlasov equation with and without a non-Markovian binary
collision term at finite temperature. We calculate the giant dipole resonance
(GDR) strength function for finite nuclei using Steinwedel-Jensen model and
also by Thomas-Fermi approximation, and we compare them for 120Sn and 208Pb
with experimental results.Comment: 15 pages, 4 figure
Association of polymorphisms in APOE, p53, and p21 with primary open-angle glaucoma in Turkish patients
Purpose To investigate the association between Apolipoprotein E (APOE), tumor suppressor protein p53 (p53), and cyclin-dependent kinase inhibitor 1A (p21) genes and primary open-angle glaucoma (POAG) in a cohort of Turkish subjects. Methods Seventy-five POAG patients (49 women, 26 men) and 119 healthy subjects (67 women, 52 men) were genotyped with polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Allele and genotype frequencies between healthy subjects and glaucoma patients were compared by the χ2 test, and intraocular pressure (IOP), cup/disc ratio (C/D) and visual field indices (MD and PSD) were compared among different APOE, p53, and p21 genotypes in POAG group. A p value 0.05). POAG subjects with the ε2ε3 genotype had a worse PSD value (median=2.2) than those with the ε3ε4 genotype (median=1.77; p=0.01) and POAG subjects with the ε3ε3 genotype had worse MD and PSD values (median= -7.4 and 3.4, respectively) than those with the ε3ε4 genotype (median= -4.1 and 1.77, respectively; p=0.034 and 0.028, respectively). Conclusions Our study found no link between polymorphisms in APOE, p53, and p21 genes and POAG in Turkish patients, although a larger sample is required to elucidate the role of these polymorphisms in the pathogenesis and course of glaucoma
Thin film MoS2 nanocrystal based ultraviolet photodetector
Cataloged from PDF version of article.We report on the development of UV range photodetector based on molybdenum disulfide nanocrystals (MoS2-NCs). The inorganic MoS2-NCs are produced by pulsed laser ablation technique in deionized water and the colloidal MoS2-NCs are characterized by transmission electron microscopy, Raman spectroscopy, X-ray diffraction and UV/VIS absorption measurements. The photoresponse studies indicate that the fabricated MoS2-NCs photodetector (MoS2-NCs PD) operates well within 300-400 nm UV range, with diminishing response at visible wavelengths, due to the MoS2-NCs absorption characteristics. The structural and the optical properties of laser generated MoS2-NCs suggest promising applications in the field of photonics and optoelectronics. (C) 2012 Optical Society of Americ
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Synthesis and Evaluation of a Conjugate Vaccine Composed of Staphylococcus aureus Poly-N-Acetyl-Glucosamine and Clumping Factor A
The increasing frequency, severity and antimicrobial resistance of Staphylococcus aureus infections has made the development of immunotherapies against this pathogen more urgent than ever. Previous immunization attempts using monovalent antigens resulted in at best partial levels of protection against S. aureus infection. We therefore reasoned that synthesizing a bivalent conjugate vaccine composed of two widely expressed antigens of S. aureus would result in additive/synergetic activities by antibodies to each vaccine component and/or in increased strain coverage. For this we used reductive amination, to covalently link the S. aureus antigens clumping factor A (ClfA) and deacetylated poly-N-β-(1–6)-acetyl-glucosamine (dPNAG). Mice immunized with 1, 5 or 10 µg of the dPNAG-ClfA conjugate responded in a dose-dependent manner with IgG to dPNAG and ClfA, whereas mice immunized with a mixture of ClfA and dPNAG developed significantly lower antibody titers to ClfA and no antibodies to PNAG. The dPNAG-ClfA vaccine was also highly immunogenic in rabbits, rhesus monkeys and a goat. Moreover, affinity-purified, antibodies to ClfA from dPNAG-ClfA immune serum blocked the binding of three S. aureus strains to immobilized fibrinogen. In an opsonophagocytic assay (OPKA) goat antibodies to dPNAG-ClfA vaccine, in the presence of complement and polymorphonuclear cells, killed S. aureus Newman and, to a lower extent, S. aureus Newman ΔclfA. A PNAG-negative isogenic mutant was not killed. Moreover, PNAG antigen fully inhibited the killing of S. aureus Newman by antisera to dPNAG-ClfA vaccine. Finally, mice passively vaccinated with goat antisera to dPNAG-ClfA or dPNAG-diphtheria toxoid conjugate had comparable levels of reductions of bacteria in the blood 2 h after infection with three different S. aureus strains as compared to mice given normal goat serum. In conclusion, ClfA is an immunogenic carrier protein that elicited anti-adhesive antibodies that fail to augment the OPK and protective activities of antibodies to the PNAG cell surface polysaccharide
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