324 research outputs found
On the vanishing viscosity limit in a disk
We say that the solution u to the Navier-Stokes equations converges to a
solution v to the Euler equations in the vanishing viscosity limit if u
converges to v in the energy norm uniformly over a finite time interval.
Working specifically in the unit disk, we show that a necessary and sufficient
condition for the vanishing viscosity limit to hold is the vanishing with the
viscosity of the time-space average of the energy of u in a boundary layer of
width proportional to the viscosity due to modes (eigenfunctions of the Stokes
operator) whose frequencies in the radial or the tangential direction lie
between L and M. Here, L must be of order less than 1/(viscosity) and M must be
of order greater than 1/(viscosity)
Healthcare system priorities for successful integration of genomics: An Australian focus
This paper examines key considerations for the successful integration of genomic technologies into healthcare systems. All healthcare systems strive to introduce new technologies that are effective and affordable, but genomics offers particular challenges, given the rapid evolution of the technology. In this context we frame internationally relevant discussion points relating to effective and sustainable implementation of genomic testing within the strategic priority areas of the recently endorsed Australian National Health Genomics Policy Framework. The priority areas are services, data, workforce, finances, and person-centred care. In addition, we outline recommendations from a government perspective through the lens of the Australian health system, and argue that resources should be allocated not to just genomic testing alone, but across the five strategic priority areas for full effectiveness
Religious diversity, empathy, and God images : perspectives from the psychology of religion shaping a study among adolescents in the UK
Major religious traditions agree in advocating and promoting love of neighbour as well as love of God. Love of neighbour is reflected in altruistic behaviour and empathy stands as a key motivational factor underpinning altruism. This study employs the empathy scale from the Junior Eysenck Impulsiveness Questionnaire to assess the association between empathy and God images among a sample of 5993 religiously diverse adolescents (13â15 years old) attending state maintained schools in England, Northern Ireland, Scotland, Wales, and London. The key psychological theory being tested by these data concerns the linkage between God images and individual differences in empathy. The data demonstrate that religious identity (e.g. Christian, Muslim) and religious attendance are less important than the God images which young people hold. The image of God as a God of mercy is associated with higher empathy scores, while the image of God as a God of justice is associated with lower empathy scores
Isospin Effects in Nuclear Multifragmentation
We develop an improved Statistical Multifragmentation Model that provides the
capability to calculate calorimetric and isotopic observables with precision.
With this new model we examine the influence of nuclear isospin on the fragment
elemental and isotopic distributions. We show that the proposed improvements on
the model are essential for studying isospin effects in nuclear
multifragmentation. In particular, these calculations show that accurate
comparisons to experimental data require that the nuclear masses, free energies
and secondary decay must be handled with higher precision than many current
models accord.Comment: 46 pages, 16 figure
Quark propagator and vertex: systematic corrections of hypercubic artifacts from lattice simulations
This is the first part of a study of the quark propagator and the vertex
function of the vector current on the lattice in the Landau gauge and using
both Wilson-clover and overlap actions. In order to be able to identify lattice
artifacts and to reach large momenta we use a range of lattice spacings. The
lattice artifacts turn out to be exceedingly large in this study. We present a
new and very efficient method to eliminate the hypercubic (anisotropy)
artifacts based on a systematic expansion on hypercubic invariants which are
not SO(4) invariant. A simpler version of this method has been used in previous
works. This method is shown to be significantly more efficient than the popular
``democratic'' methods. It can of course be applied to the lattice simulations
of many other physical quantities. The analysis indicates a hierarchy in the
size of hypercubic artifacts: overlap larger than clover and propagator larger
than vertex function. This pleads for the combined study of propagators and
vertex functions via Ward identities.Comment: 14 pags., 9 fig
A statistical interpretation of the correlation between intermediate mass fragment multiplicity and transverse energy
Multifragment emission following Xe+Au collisions at 30, 40, 50 and 60 AMeV
has been studied with multidetector systems covering nearly 4-pi in solid
angle. The correlations of both the intermediate mass fragment and light
charged particle multiplicities with the transverse energy are explored. A
comparison is made with results from a similar system, Xe+Bi at 28 AMeV. The
experimental trends are compared to statistical model predictions.Comment: 7 pages, submitted to Phys. Rev.
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells
Brain malignancies encompass a range of primary and metastatic cancers, including low-grade and high-grade gliomas and brain metastases (BrMs) originating from diverse extracranial tumors. Our understanding of the brain tumor microenvironment (TME) remains limited, and it is unknown whether it is sculpted differentially by primary versus metastatic disease. We therefore comprehensively analyzed the brain TME landscape via flow cytometry, RNA sequencing, protein arrays, culture assays, and spatial tissue characterization. This revealed disease-specific enrichment of immune cells with pronounced differences in proportional abundance of tissue-resident microglia, infiltrating monocyte-derived macrophages, neutrophils, and T cells. These integrated analyses also uncovered multifaceted immune cell activation within brain malignancies entailing converging transcriptional trajectories while maintaining disease- and cell-type-specific programs. Given the interest in developing TME-targeted therapies for brain malignancies, this comprehensive resource of the immune landscape offers insights into possible strategies to overcome tumor-supporting TME properties and instead harness the TME to fight cancer
InfluĂȘncia de prĂĄticas culturais e da resistĂȘncia genĂ©tica na intensidade do cancro da haste e produção de soja no Cerrado
Os efeitos de prĂĄticas culturais e resistĂȘncia genĂ©tica na intensidade ao cancro-da-haste da soja (Diaporthe phaseolorum f.sp. meridionalis - Dpm) foram examinados na safra 1995-96 em ĂĄreas de produção comercial, que haviam sido severamente atacadas na safra anterior (1994-95). Um experimento investigou os efeitos de cultivo mĂnimo (MT) e do plantio direto (NT) no desenvolvimento da doença e produtividade das cultivares FT-Cristalina e FT-Seriema. Em outro experimento, semeado em plantio direto, estudou-se o efeito da densidade de plantas (8, 15, 21 e 36 plantas/m) no desenvolvimento da doença e produtividade das cvs. FT-Cristalina (suscetivel), FT- 101 (moderadamente resistente) e FT-104 (resistente). IncidĂȘncia e severidade da doença foram menores em NT do que em MT. A produtividade aumentou no sistema NT (23% para âFT-Cristalinaâ e 14% para âFT-Seriemaâ), comparada com as produtividades em MT. As curvas de progresso da doença foram melhor descritas pelos mo- delos de Gompertz e logĂstico. A severidade do cancro aumentou pro- porcionalmente ao aumento das densidades de plantio nas cvs. suscetĂvel e moderadamente resistente. No final do ciclo, 100% das plantas da cv. FT-Cristalina estavam infetadas por Dpm, em todas as densidades de plantio. NĂveis intermediĂĄrios de doença foram observa- dos na cv. FT-101, enquanto apenas nĂveis muito baixos de doença ocorreram na cv. FT-104. Estabeleceu-se uma correlação negativa entre severidade de cancro-da-haste e produção. Algumas das prĂĄticas estudadas demonstraram potential para aplicação direta no controle da doença, e poderiam ser combinadas considerando-se seus efeitos aditivos.Field experiments were conducted in the 1995-96 soybean (Glycine max) growing season to evaluate the effects of cultural practices and host genetic resistance on the intensity of soybean stem canker, caused by Diaporthe phaseolorum f.sp. meridionalis (Dpm). Experiments were conducted in a commercial field severely infected in the previous (1994-95) season. In one study, minimum tillage (MT) and no-tillage (NT) cropping systems were investigated for their effects on disease development and on plant yields in cvs. FT- Cristalina (susceptible) and FT-Seriema (moderately resistant). Another study evaluated the effects of plant densities (8, 15, 21 and 36 plants/m) on disease development in cvs. FT-Cristalina, FT-101 (moderately resistant) and FT-104 (resistant). Disease incidence and severity were consistently lower in NT than in MT, and plant yields were increased by 23% and 14% in the NT system for the susceptible and moderately resistant cultivars, respectively, compared to the yields in the MT system. The Gompertz and Logistic models described well the disease progress curves in all situations. For both susceptible and moderately resistant cultivars, disease severity increased proportionately to the increase in plant densities. At the end of the season, 100% of the plants of cv. FT-Cristalina were infected by Dpm, at all plant densities. Disease levels on cv. FT-101 were intermediate while only very low disease levels were recorded on cv. FT-104. There was a consistent negative correlation between stem canker severity and yield. Some practices demonstrated potential for direct application in disease control, and could be combined considering their additive effects
Use of filter papers to determine seroprevalence of Toxoplasma gondii among hunted ungulates in remote Peruvian Amazon
Toxoplasmosis is a zoonosis caused by the protozoan Toxoplasma gondii, and it is found worldwide. To determine whether ungulates are reservoirs of T. gondii in an isolated and remote region of the northeastern Peruvian Amazon, antibodies to T. gondii were determined in 5 species of ungulates by the modified agglutination test (MAT). These animals were hunted by subsistence hunters along the YavarĂ-MirĂn River, in the northeastern Peruvian Amazon. Blood samples were collected by hunters on filter papers. For determination of T. gondii antibodies, blood was eluted from filter papers, and a titer of 1:25 was considered indicative of exposure to T. gondii. Antibodies to T. gondii were found in 26 (31.0%) peccaries (Pecari tajacu, Tayassu pecari), six (17.1%) brocket deer (Mazama americana, Mazama gouazoubira), and four (40.0%) lowland tapir (Tapirus terrestris). We also introduced a modification to the MAT protocol that allows the extraction of fluid samples from several types of laboratory-grade filter paper, thus enabling researchers to easily adapt their approaches to the materials presented to them
Excitation and decay of projectile-like fragments formed in dissipative peripheral collisions at intermediate energies
Projectile-like fragments (PLF:15<=Z<=46) formed in peripheral and
mid-peripheral collisions of 114Cd projectiles with 92Mo nuclei at E/A=50 MeV
have been detected at very forward angles, 2.1 deg.<=theta_lab<=4.2 deg.
Calorimetric analysis of the charged particles observed in coincidence with the
PLF reveals that the excitation of the primary PLF is strongly related to its
velocity damping. Furthermore, for a given V_PLF*, its excitation is not
related to its size, Z_PLF*. For the largest velocity damping, the excitation
energy attained is large, approximately commensurate with a system at the
limiting temperatureComment: 5 pages, 6 figure
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