58 research outputs found

    Maternal exposure to ambient black carbon particles and their presence in maternal and fetal circulation and organs : an analysis of two independent population-based observational studies

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    Funding European Research Council, Flemish Scientific Research Foundation, Kom op Tegen Kanker, UK Medical Research Council, and EU Horizon 2020. Acknowledgments The ENVIRONAGE birth cohort was initiated by the European Research Council (ERC-2012-StG 310898) and received additional funding from the Flemish Scientific Research Foundation and Kom op Tegen Kanker (KoTK). The detection equipment was funded by the METHUSALEM Program and the INCALO project (ERC-PoC). We acknowledge the Flemish Scientific Research Foundation (FWO; 1150920N to EB and G082317N). The SAFeR study was funded by the UK Medical Research Council (MR/L010011/1 and MR/P011535/1) and the EU's Horizon 2020 research and innovation programme under the Marie SkƂodowska-Curie project PROTECTED (grant agreement number 722634) and FREIA project (grant agreement number 825100) as well as by NHS Grampian Endowments grants (16/11/056, 17/034, 18/14, 19/029, and 20/031) to PAF. We thank the midwives from the maternity ward of the East-Limburg Hospital in Genk, Belgium, for coordinating and supporting the study at the ward. We thank the Advanced Optical Microscopy Centre for the maintenance of the microscopic instruments. Moreover, we thank our colleagues from the Centre for Environmental Sciences for their hard work in collecting and processing the samples for the ENVIRONAGE birth cohort. Additionally, we thank the NHS Grampian Research Nurses and NHS Grampian R&D for their tireless recruitment work for the SAFeR study. We thank the past and present SAFeR team for their hard work with the fetuses and placentae. Finally, we thank the NHS Grampian Biorepository for their oversight role in SAFeR and assistance in processing and preparation of tissue sections.Peer reviewedPublisher PD

    Sequencing of diverse mandarin, pummelo and orange genomes reveals complex history of admixture during citrus domestication

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    Cultivated citrus are selections from, or hybrids of, wild progenitor species whose identities and contributions to citrus domestication remain controversial. Here we sequence and compare citrus genomes-a high-quality reference haploid clementine genome and mandarin, pummelo, sweet-orange and sour-orange genomes-and show that cultivated types derive from two progenitor species. Although cultivated pummelos represent selections from one progenitor species, Citrus maxima, cultivated mandarins are introgressions of C. maxima into the ancestral mandarin species Citrus reticulata. The most widely cultivated citrus, sweet orange, is the offspring of previously admixed individuals, but sour orange is an F1 hybrid of pure C. maxima and C. reticulata parents, thus implying that wild mandarins were part of the early breeding germplasm. A Chinese wild 'mandarin' diverges substantially from C. reticulata, thus suggesting the possibility of other unrecognized wild citrus species. Understanding citrus phylogeny through genome analysis clarifies taxonomic relationships and facilitates sequence-directed genetic improvement. (Résumé d'auteur

    The Intellectual as a Contemporary Phenomenon

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    A reading of Spinoza and Negri in order to rethink the terms of intellectual contemporaneity in liberatory rather than merely historical terms.BovĂ© Ă©labore une vision libĂ©ratrice plutĂŽt que simplement historiciste de l’actualitĂ© de l’intellectuel, Ă  travers une lecture de Spinoza et de Negri

    NOTES TOWARDS A POLITICS OF "AMERICAN" CRITICISM

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    A meditation on the nature of oppositional criticism and the problems of opposition within and to the discipline and discourse of "American Studies".Une rĂ©flexion sur la nature de la critique oppositionnelle et les problĂšmes de l’opposition Ă  l’intĂ©rieur et Ă  l’encontre de la discipline et du discours des Études AmĂ©ricaines

    BIM for heritage science: a review

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    Abstract Building Information Modelling (BIM) is a new process that is spreading in the Architecture, Engineering and Construction field. It allows the creation of virtual building models, which can be linked to numerical data, texts, images, and other types of information. Building components, such as walls, floors, etc. are modelled as “smart objects”, i.e. they are defined by numerical parameters, such as dimensions, and are embedded with other kinds of information, such as building materials and properties. Stored data are accessible and modifiable by all different professionals involved in the same project. The BIM process has been developed for new buildings, and it allows to plan and manage the whole building life-cycle. BIM for built heritage has started to be researched recently, and its use is still not widespread. Indeed, built heritage is characterised by complex morphology and non-homogeneous features, which clash with BIM’s standardised procedures. Moreover, to date, BIM does not allow fully automated procedures to model heritage buildings. This review focuses on the survey and digitisation phases, which can be seen as the initial phases of application of BIM in conservation projects. It also briefly covers the modelling stage. Here we present the main methodologies developed for BIM for built heritage. Issues about digitisation are also highlighted, principally in connection with the unavailability of automated processes. During the last 10 years, research has led to promising results; for example, videogame interfaces have been used to simulate virtual 3D tours that display in a single interface the 3D model and the database containing metadata, and new software plug-ins have been developed, to easily create “smart objects”. Nevertheless, further research is needed to establish how BIM can support the practice of building conservation. There is a gap in BIM’s information holding capacities, namely the storage of cultural and historical documentation, as well as monitored and simulated data relevant for preventive conservation. Future work should focus on the development of new tools that will be able to store and share all the relevant metadata
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