Rate baladeuse associée à une anomalie de Neuhauser: à propos d’un cas

La rate baladeuse est une entité anatomique rare pouvant être d’origine congénitale ou acquise. Son diagnostic se fait souvent suite à une torsion de son pédicule ou fortuitement lors d’un examen d’imagerie. L’association à une autre anomalie congénitale est exceptionnelle et n’a pas été décrite dans la littérature. Nous rapportant le cas d’une association d’une rate pelvienne à une anomalie de Neuhauser longtemps asymptomatiques et de découverte fortuite lors d’une TDM thoraco-abdomino-pelvienne faite dans le cadre d’un bilan d’extension d’un adénocarcinome chez un homme de 86 ans.Pan African Medical Journal 2016; 2

Pentamethylcyclopentadienyl ruthenium: an efficient catalyst for the redox isomerization of functionalized allylic alcohols into carbonyl compounds

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A new access to the 6,8-dioxabicyclo[3.2.1]octane ring system using a three-component reaction : enantioselective synthesis of (+)-iso-exo-brevicomin

International audienceThe combination of a catalytic hetero-Diels-Alder-­allylboration sequence and a ruthenium-catalyzed isomerization of an allylic alcohol moiety as key steps open a new route for the asymmetric synthesis of 6,8-dioxabicyclo[3.2.1]octane subunits. The application of this strategy to the synthesis of (+)-iso-exo-brevi­comin is also reported

Association between pancreatic cancer and diabetes: insights from a retrospective cohort study

Abstract Background Studies investigating the prevalence of pancreatic cancer have revealed a heightened risk of 1.5 to 2.0 times among individuals with long-standing type 2 diabetes mellitus. Aims We aimed to estimate the prevalence of diabetes among patients with pancreatic cancer, and identify the factors associated with type 2 diabetes mellitus in this population. Methods This retrospective observational and analytical study was carried out in the Department of Gastroenterology of the Mohammed VI University Hospital over a period of 5 years, between 2018 and 2022, including all patients with confirmed cases of pancreatic adenocarcinoma. Results Out of the 197 patients, 38.1% had a history of diabetes, among them, 42.7% had new-onset diabetes, while the remaining 57.3% had long-standing diabetes. Diabetic patients were significantly older than nondiabetic patients (mean age of 67.2 vs. 63, P = 0.009). Diabetes was more prevalent among obese patients (66.7%, P = 0.01), and less frequent among individuals with chronic alcohol consumption (20% vs. 80%, P = 0.04), and tobacco smokers (24.4% vs75.6%, P = 0.03). Among patients with an ECOG score ≥ 3, DM, 54.5% were DM-patients (P = 0.033). The same significant association was found for the Nutritional Risk Index, Patients who had moderate or severe malnutrition were more likely to be diabetic 74.7% (P = 0.004). Diabetic patients were less likely to undergo surgery due to comorbidities and general health deterioration. However, no significant differences were observed in sex, tumor stage or location. Conclusion Our study has shown an increased prevalence of diabetes in pancreatic cancer and highlights the importance of considering this cancer in cases of recent onset or uncontrolled diabetes, especially in elderly individuals