Optimization of empty container movements using street-turn: Application to Valencia hinterland

Empty maritime container logistics is one of the most relevant costs for shipping companies. In this paper two mathematical models (based on two different container movement patterns, i.e. with and without street-turns) were defined to optimize land empty container movements among shippers, consignees, terminals and depots, along with minimizing storage costs. One of the proposed optimization models was embedded in a simple Decision Support System (DSS) and then tested with real data, based on the operations in Valencia s (Spain) hinterland. The results obtained confirm the benefits of implementing these kinds of models for the company, and additional experiments assess and quantify the advantage of using the more complex approach that is able to implement street-turn patterns.This research has been funded by the Spanish Ministry of Science and Innovation through Grant DPI2010-16201 and FEDER.Furió, S.; Andrés Romano, C.; Adenso Díaz, B.; Lozano Segura, S. (2013). Optimization of empty container movements using street-turn: Application to Valencia hinterland. Computers and Industrial Engineering. 66(4):909-917. https://doi.org/10.1016/j.cie.2013.09.003S90991766

Gd(III) complexes intercalated into hydroxy double salts as potential MRI contrast agents

The ion exchange intercalation of two Gd-based magnetic resonance imaging contrast agents into hydroxy double salts (HDSs) is reported. The presence of Gd3+ diethylenetriaminepentaacetate and Gd3+ diethylenetriaminepenta(methylenephosphonate) complexes in the HDS lattice after intercalation was confirmed by microwave plasma-atomic emission spectroscopy. The structural aspects of the HDS-Gd composites were studied by X-ray diffraction, with the intercalates having an interlayer spacing of 14.5–18.6 Å. Infrared spectroscopy confirmed the presence of characteristic vibration peaks associated with the Gd3+ complexes in the intercalation compounds. The proton relaxivities of the Gd3+ complex-loaded composites were 2 to 5-fold higher in longitudinal relaxivity, and up to 10-fold higher in transverse relaxivity, compared to solutions of the pure complexes. These data demonstrate that the new composites reported here are potentially potent MRI contrast agents

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

Mitochondrial physiology

As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery

American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

10.1002/acr.23834ARTHRITIS CARE & RESEARCH715579-59

Diez dilemas morales para discusiones educativas / Ten moral dilemmas for educational discussions

[Materiales didácticos]  Bruta, ciega, sordomuda...   ¿Una nueva supermodelo adolescente?  Un candidato sobresaliente  ¡O te depilas o... !  Consejos para la campaña electoral  Una señora sollozando en la estación del Metro  Una fiesta de matiné  “Hackear” o no “hackear”  Un perro atrapado  Me muero por unas alitas de pollo &nbsp