The Ministering Angel

Scholarships & Prizes Office. University of Sydne

The Ministering Angel

Scholarships & Prizes Office. University of Sydne

Experimental murine schistosomiasis mansoni: estabilishment of the chronic phase of the disease

After the acute hyperergic phase of schistosomal infection, the chronic phase of the disease corresponds to the estabilishment of a relative equilibrium between the host and the parasite. This involves: (1) A shift from the predominance of the TH2 response observed in the acute phase, to the predominance of the TH1 response in the chronic phase of the disease, with modification of lymphokine and immunoglobulin secretions patterns. (2) Redistribution of hosts responses to parasite, with predominance of systemic controls in the acute phase, and a shift towards local tissue responses in the chronic phase. This redistribution relieves the hyperergic responses involving the whole body of the host, and delimits cellular and molecular reactions to parasites to only those tissues that are directly involved by the adult parasites and their eggs. Mobilization of eosinophil granulocytes in schistosomal periovular granulomas is one of examples of this redistribution

The effect of physical activity and sedentary behaviour on mental health amongst young adults.

Through a systematic review, cross-sectional and longitudinal studies, the current thesis found that physical activity was associated with reduced mental health symptoms; however, this effect was not maintained after multivariate control for young adult psychosocial characteristics. Further, engagement in long periods of sedentary behaviour (sitting time) was associated with higher psychological distress in the cross-sectional study, but not related in the longitudinal study. A significant contribution of the thesis was the finding of a threshold at which sitting time may be related to mental health

Yrkesretting av fellesfag i videregående skole. Engelsklæreres syn på yrkesretting av engelskfaget

This master's thesis deals with English language teachers' view on vocationalization of English as a common core subject. The starting point for the study is the project Fellesfag, yrkesretting og relevans (FYR)" which is one of the national measures directed to dropout prevention in upper-secondary schools. Vocationalization is considered to be a strategy or instrument meant to motivate students to study common core subjects. The purpose of this study is to bring a deeper understanding of how English language teachers work on vocationalization, and to give insight into the relations which influence their work with this strategy. The data for the study were collected through semi-structured interviews with six English language teachers who have taught in different vocational education programmes. The applied data interpretation method is ad hoc analysis which is conducted in accordance with the principles of hermeneutic phenomenological research approach. The main findings focus on informants' understanding of vocationalization as a strategy to motivate students and contribute to acquisition of knowledge, which students will be able to use in their working life. The findings show informants' holistic view on English as a subject in vocational education programmes, pointing that vocationalization can lead to the negligence of the dimension of Bildung in English subject. According to the informants, vocationalization is likely to motivate and include the low-performing students in a community of interest. However, motivation and inclusion through vocational themes do not necessarily lead to good results on exams and assessments of students' knowledge. The study shows that there are several interrelated factors which should be considered together in order to contribute to a better understanding of vocationalization and the scope of English teachers activities when applying this strategy. The findings of the study are discussed through the selected theories related to sociocultural perspectives on learning/teaching, knowledge transfer between education and workplace settings, and perspectives on the universal education system in Norway.Masteroppgaven omhandler engelsklæreres syn på yrkesretting av engelskfaget. Den tar utgangspunkt i prosjektet Fellesfag, yrkesretting og relevans (FYR) som er ett av de nasjonale tiltakene rettet mot frafallet i videregående opplæring. Yrkesretting betraktes blant annet som strategi og virkemiddel for å motivere elever på yrkesfaglige utdanningsprogrammer til å lære fellesfag. Formålet med oppgaven er å oppnå dybdeforståelse av engelsklæreres arbeid med yrkesretting og av forhold som kan være viktig for yrkesretting. Datamaterialet er hentet inn gjennom kvalitative intervjuer med seks engelsklærere som har undervist på forskjellige yrkesfaglige studieretninger. Det er tolket fra et fenomenologisk- hermeneutisk vitenskapsteoretisk ståsted og gjennom ad hoc analysemetode. Hovedfunnene fokuserer på deltakernes forståelse av begrepet yrkesretting som en strategi for å motivere elever og bidra til tilegnelse av kunnskaper som elevene kan bruke i arbeidslivet. De viser deltakernes helhetlige syn på engelskfaget som inngår i yrkesfaglige programmer, og peker på at anvendelse av yrkesretting kan føre til neglisjering av dannelsesdimensjon ved engelskfaget. Gjennom yrkesrettede emner er det mulig å motivere og inkludere svake elever i et interessefellesskap. Imidlertid viser funnene at motivering og inkludering ikke nødvendigvis fører til gode resultater på vurderinger og eksamener. Elever på yrkesfaglige studieretninger kan bli trukket til sentralgitt eksamen i engelsk på samme vilkår som elever på studiespesialiserende programmer. Denne eksamensformen er sett på som en hovedfaktor som senker fokus på yrkesretting. I tillegg synes det å være flere sammenhengende forhold, som samlet sett kan bidra til en utfyllende forståelse av yrkesretting og engelsklæreres handlingsrom ved anvendelse av denne strategien. På grunn av indikasjoner i tidligere forskning om lite teori i studier som angår yrkesretting, er funnene i prosjektet diskutert i lys av teorier om sosiokulturelt syn på undervisning og læring, teorier om overføring av kunnskaper mellom skolekontekst og arbeidslivskontekst, samt perspektiver på det norske universalistiske utdanningssystemet.Master i PedagogikkPED395MAPS-PE

Uso de nanopartículas no rastreamento de células em terapias avançadas: possibilidades e desafios para a aplicação clínica

Introduction: Regulation and introduction of new advanced cellular technologies in clinics requires better knowledge on the used cells. One of the major challenges is the difficulty to accurately determine the mechanisms of cell activities when submitted to advanced therapies. Objective: Understand, using the cell tracking methods, the tissue distribution and the molecular response of cells exposed to advanced therapies. Methods: This work was done as an integrated review of data collected in international data-bases and of legislations concerning the clinical use of nanoparticles. Results: Nanotechnology is a very useful tool for cell tracking in vivo, and several nanoparticles have been already approved for clinical use; they can be incorporated into cells and visualized by magnetic resonance imaging. Conclusions: The perspectives on the use of nanomedicines for cellular tracking in medical clinic are promising, requiring elaboration and approval of laws, guides and norms to orient the industrial sectors, regarding the nanomaterials characterization and potential risks to human and animal health, as well as to the environment.Introdução: Para uma regulamentação específica e implementação das novas tecnologias avançadas na clínica médica, é preciso refinar o conhecimento sobre as células utilizadas. Um dos maiores desafios está na dificuldade em determinar os mecanismos de funcionamento das células após a terapia. Objetivo: Compreender, usando os métodos de rastreamento celular em pacientes, a distribuição e a função de células usadas em terapias avançadas. Método: Este trabalho foi elaborado pelo levantamento de artigos científicos nas bases de dados internacionais e da legislação vigente sobre a utilização clínica das nanopartículas. Resultados: Constatamos que a nanotecnologia já é uma ferramenta de grande utilidade, pois diversas nanopartículas magnéticas já são aprovadas para uso clínico; elas podem ser incorporadas por células e visualizadas por imagens de ressonância magnética. O presente texto discute as perspectivas sobre uso de nanomedicamentos para rastreamento celular na clínica médica. Conclusões: A utilização das nanopartículas necessita a elaboração e aprovação de leis, guias e normas que orientem a indústria, como outros setores, sobre a caracterização dos nanomateriais e potenciais riscos à saúde humana, animal e ao meio ambiente

Strategic analysis of textile manufacturing industry : case of Croatia

The textile manufacturing industry in Croatia has set its foundations during the existence of Yugoslavia, and was then one of the most successful industries in Croatia. Marked by a large number of employees, the majority of women with secondary school education, it was an industry in which has operated a small number of large companies with many employees. Croatian textile manufacturing industry still has the major role in Croatian economy. Despite many changes and difficulties caused by the reduction of the market, the industry has maintained a very important place in the Croatian economy. The position of the textile manufacturing industry is very complex, given the economic, but also the global situation. Thus, the main goal of this paper is to analyze the textile manufacturing industry on the sample of Croatian manufacturing firms. The aim was to define the importance of the textile industry in Croatia using Porter's model of five competitive forces, and also to determine the key segments needed for success and further development of the textile industry. Furthermore, the analysis will give us a clear insight into the economic aspects of the textile industry and all of the factors and forces that have the influence on the industry development and all the opportunities and threats that work in this industry. The result showed that the textile industry in Croatia is threatening further strengthening power of suppliers and buyers, unless there is a connection and association of enterprises. Great threat whose intensity enhances is the entry of new competitors, both domestic and large competitors from foreign markets.peer-reviewe

Composição contendo frações de células de Leishmania, denominadas antígeno FML "fucose mannose ligand" ou "ligante de fucose-manose", uso do antígeno FML e de suas subfrações e componentes para as aplicações em imunodiagnóstico específico da leishmaniose visceral humana e animal, para aplicações em vacinação, tratamento ou imunoterapia contra a leishmaniose visceral humana e canina

Em 28/04/1998: Desistência homologada. Notificação da homologação da desistência do pedido de patente, apresentada pelo depositante, acarretando o encerramento do processo administrativo.Não concedidaPatente de invenção: "composições contendo frações nativas de células de Leishmania, denominadas antígeno FML "Ligante de Fucose Manose" e do uso deste antígeno FML e de suas subfrações e componentes: glicoproteínas de 36,55 kd, e outras proteínas, adicionadas ou não de veículos farmacológicos, para as aplicações em imunodiagnóstico específico da leishmaniose visceral humana e animal, e para as aplicações em vacinação, tratamento ou imunoterapia contra a leishmaniose visceral humana e canina