Avaliação nutricional de praticantes de musculação de uma academia do Centro de Criciúma-SC

A musculação é uma modalidade praticada por indivíduos de ambos os sexos, com idades variadas e com diferentes objetivos, entre eles se destaca a hipertrofia muscular. A busca por esse modelo de corpo desejado envolve muitas mudanças no cotidiano de quem tem esse objetivo, a principal delas é a alimentação que precisa ser ajustada. O objetivo do estudo foi verificar os hábitos alimentares e o consumo de suplementos por praticantes de musculação que visam hipertrofia, e de onde os mesmos obtêm as informações sobre as orientações nutricionais recomendadas. A amostra do estudo foi composta por 35 praticantes de musculação de uma academia do centro de Criciúma, com idade entre 18 e 50 anos, de ambos os sexos, que praticam a modalidade de musculação. Para a coleta de dados foi utilizado um questionário de frequência de consumo alimentar (QFCA), onde a este foram acrescentadas questões referentes a prescrição de dietas e ao consumo de suplementos alimentares. Verificou-se no estudo que apesar do cuidado pela maioria dos praticantes com o excesso de gorduras e açúcares, a ingestão de frutas, verduras e hortaliças se encontram pobres. O consumo de suplementos foi muito elevado se comparado a outros estudos recentes, dentre eles o Whey Protein foi o que mais se destacou. Por fim, concluiu-se que a forma mais adequada para se chegar ao objetivo desejado é a procura de um profissional habilitado, pois só ele poderá adequar a quantidade de nutrientes necessária para cada indivíduo. ABSTRACT Nutritional assessment of weight training practitioners of an academy of Criciuma Center-SCBodybuilding is a sport practiced by individuals of both sexes, different ages, and seeking different objectives including the highly desired muscular hypertrophy. The pursuit of this body model involves many changes in everyday practices, mainly the dietary changes that need to be set. The aim of this study is to determine the eating habits and the consumption of supplements by bodybuilders pursuing hypertrophy, and where these individuals attain the recommended nutritional guideline information. The study sample consists of 40 weight trainers from a gym in Criciuma, aged between 18 and 50, and consisting of  both sexes. For data collection was used a questionnaire of food intake frequency (FFQ), where this was added questions referring to prescription of diets and consumption of dietary supplements. The data shows that in spite of most practitioners carefully monitoring excess fats and sugars, their intake of fruits and vegetables is poor. Supplement use is very high compared to other recent studies, among them Whey Protein is what stood out. Finally, it is concluded that the most adequate way to reach one’s desired goal is by finding a qualified professional who can adjust the amount of nutrients required for each individual

Effects of anastrozole on Ki-67 antigen expression in the vaginal epithelium of female rats in persistent estrus

OBJECTIVES: Aromatase inhibitors are the first-choice drugs for the treatment of hormone sensitive breast cancer. However, in addition to the scarcity of studies, there are controversies about their effects on vaginal epithelial cell proliferation in rats, especially those in persistent estrus. METHODS: To investigate vaginal epithelial cell proliferation by Ki-67 antigen expression, persistent estrus was induced in 42 randomly selected rats. These rats were randomly divided into 2 groups: group I (control, n=21), which received 0.1 mL of propylene glycol (vehicle) daily, and group II (experimental, n=21), which received 0.5 mg/kg or 0.125 mg/day of anastrozole diluted with 0.1 mL of propylene glycol. RESULTS: Light microscopy showed a higher concentration of cells with brown Ki-67 stained nuclei in the control compared to the experimental group. The mean percentage of Ki-67 stained nuclei per 500 cells in the vaginal epithelium was 68.64±2.64 and 30.46±2.00 [mean±standard error of the mean (SEM)] in the control and experimental groups, respectively (po0.003). CONCLUSION: This study showed that anastrozole, at the dose and treatment duration selected, significantly decreased cell proliferation in the vaginal mucosa of the rats in persistent estrus

Mortality from gastrointestinal congenital anomalies at 264 hospitals in 74 low-income, middle-income, and high-income countries: a multicentre, international, prospective cohort study

Summary Background Congenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital anomalies are fatal without timely access to neonatal surgical care, but few studies have been done on these conditions in low-income and middle-income countries (LMICs). We compared outcomes of the seven most common gastrointestinal congenital anomalies in low-income, middle-income, and high-income countries globally, and identified factors associated with mortality. Methods We did a multicentre, international prospective cohort study of patients younger than 16 years, presenting to hospital for the first time with oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation, and Hirschsprung’s disease. Recruitment was of consecutive patients for a minimum of 1 month between October, 2018, and April, 2019. We collected data on patient demographics, clinical status, interventions, and outcomes using the REDCap platform. Patients were followed up for 30 days after primary intervention, or 30 days after admission if they did not receive an intervention. The primary outcome was all-cause, in-hospital mortality for all conditions combined and each condition individually, stratified by country income status. We did a complete case analysis. Findings We included 3849 patients with 3975 study conditions (560 with oesophageal atresia, 448 with congenital diaphragmatic hernia, 681 with intestinal atresia, 453 with gastroschisis, 325 with exomphalos, 991 with anorectal malformation, and 517 with Hirschsprung’s disease) from 264 hospitals (89 in high-income countries, 166 in middleincome countries, and nine in low-income countries) in 74 countries. Of the 3849 patients, 2231 (58·0%) were male. Median gestational age at birth was 38 weeks (IQR 36–39) and median bodyweight at presentation was 2·8 kg (2·3–3·3). Mortality among all patients was 37 (39·8%) of 93 in low-income countries, 583 (20·4%) of 2860 in middle-income countries, and 50 (5·6%) of 896 in high-income countries (p<0·0001 between all country income groups). Gastroschisis had the greatest difference in mortality between country income strata (nine [90·0%] of ten in lowincome countries, 97 [31·9%] of 304 in middle-income countries, and two [1·4%] of 139 in high-income countries; p≤0·0001 between all country income groups). Factors significantly associated with higher mortality for all patients combined included country income status (low-income vs high-income countries, risk ratio 2·78 [95% CI 1·88–4·11], p<0·0001; middle-income vs high-income countries, 2·11 [1·59–2·79], p<0·0001), sepsis at presentation (1·20 [1·04–1·40], p=0·016), higher American Society of Anesthesiologists (ASA) score at primary intervention (ASA 4–5 vs ASA 1–2, 1·82 [1·40–2·35], p<0·0001; ASA 3 vs ASA 1–2, 1·58, [1·30–1·92], p<0·0001]), surgical safety checklist not used (1·39 [1·02–1·90], p=0·035), and ventilation or parenteral nutrition unavailable when needed (ventilation 1·96, [1·41–2·71], p=0·0001; parenteral nutrition 1·35, [1·05–1·74], p=0·018). Administration of parenteral nutrition (0·61, [0·47–0·79], p=0·0002) and use of a peripherally inserted central catheter (0·65 [0·50–0·86], p=0·0024) or percutaneous central line (0·69 [0·48–1·00], p=0·049) were associated with lower mortality. Interpretation Unacceptable differences in mortality exist for gastrointestinal congenital anomalies between lowincome, middle-income, and high-income countries. Improving access to quality neonatal surgical care in LMICs will be vital to achieve Sustainable Development Goal 3.2 of ending preventable deaths in neonates and children younger than 5 years by 2030

Avaliação nutricional de praticantes de musculação de uma academia do Centro de Criciúma-SC

Nutritional assessment of weight training practitioners of an academy of Criciuma Center-SCBodybuilding is a sport practiced by individuals of both sexes, different ages, and seeking different objectives including the highly desired muscular hypertrophy. The pursuit of this body model involves many changes in everyday practices, mainly the dietary changes that need to be set. The aim of this study is to determine the eating habits and the consumption of supplements by bodybuilders pursuing hypertrophy, and where these individuals attain the recommended nutritional guideline information. The study sample consists of 40 weight trainers from a gym in Criciuma, aged between 18 and 50, and consisting of  both sexes. For data collection was used a questionnaire of food intake frequency (FFQ), where this was added questions referring to prescription of diets and consumption of dietary supplements. The data shows that in spite of most practitioners carefully monitoring excess fats and sugars, their intake of fruits and vegetables is poor. Supplement use is very high compared to other recent studies, among them Whey Protein is what stood out. Finally, it is concluded that the most adequate way to reach one’s desired goal is by finding a qualified professional who can adjust the amount of nutrients required for each individual.A musculação é uma modalidade praticada por indivíduos de ambos os sexos, com idades variadas e com diferentes objetivos, entre eles se destaca a hipertrofia muscular. A busca por esse modelo de corpo desejado envolve muitas mudanças no cotidiano de quem tem esse objetivo, a principal delas é a alimentação que precisa ser ajustada. O objetivo do estudo foi verificar os hábitos alimentares e o consumo de suplementos por praticantes de musculação que visam hipertrofia, e de onde os mesmos obtêm as informações sobre as orientações nutricionais recomendadas. A amostra do estudo foi composta por 35 praticantes de musculação de uma academia do centro de Criciúma, com idade entre 18 e 50 anos, de ambos os sexos, que praticam a modalidade de musculação. Para a coleta de dados foi utilizado um questionário de frequência de consumo alimentar (QFCA), onde a este foram acrescentadas questões referentes a prescrição de dietas e ao consumo de suplementos alimentares. Verificou-se no estudo que apesar do cuidado pela maioria dos praticantes com o excesso de gorduras e açúcares, a ingestão de frutas, verduras e hortaliças se encontram pobres. O consumo de suplementos foi muito elevado se comparado a outros estudos recentes, dentre eles o Whey Protein foi o que mais se destacou. Por fim, concluiu-se que a forma mais adequada para se chegar ao objetivo desejado é a procura de um profissional habilitado, pois só ele poderá adequar a quantidade de nutrientes necessária para cada indivíduo

Evaluation of the accuracy of mammography, ultrasound and magnetic resonance imaging in suspect breast lesions

OBJECTIVES: In breast cancer diagnosis, mammography (MMG), ultrasonography (USG) and magnetic resonance imaging (MRI) are the imaging methods most used. There is a scarcity of comparative studies that evaluate the accuracy of these methods in the diagnosis of breast cancer. METHODS: A cross-sectional study was carried out through the review of electronic medical records of 32 female patients who underwent breast imaging examinations at a imaging diagnostic center in Teresina, State of Piauı´, Brazil. Patients who had these three imaging methods at the time of the evaluation of the same nodule were included. The nodule must have been classified as suspect by the BI-RADSs system in at least one of the methods. Data from each method were compared with the histopathological examination. Statistical analysis used the calculation of proportions in Excel 2010. RESULTS: MMG showed 56.2%, 87.5%, 81.8%, 66.7% and 71.8% of sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy, respectively. USG had 75%, 18.8%, 48%, 42.8% and 46.9% of sensitivity, specificity, PPV, NPV and accuracy, respectively. In turn, MRI had 100%, 50%, 66.7%, 100% and 75% of sensitivity, specificity, PPV, NPV and accuracy, respectively. CONCLUSION: Thus, MRI and MMG were more accurate in evaluating suspicious breast lumps. MRI had a low specificity, mainly to high breast density, while MMG had also sensitivity limited due to high breast density and USG has been proven to be useful in these patients

A rare case of primary breast angiosarcoma in a male: a case report

Abstract Background Sarcomas account for less than 1% of primary breast cancers, and breast angiosarcomas are responsible for only 0.05% of all breast malignancies. The male breast has the same potential for malignant transformation as the female breast. However, due to anatomical differences in the breast and the low incidence of angiosarcoma, it is difficult to determine how male breasts can be affected by this type of tumor. Case presentation A 36-year-old male patient was admitted to the hospital with a palpable lump in his right breast. Lymphadenopathy was negative. Ultrasonography showed a hypoechoic mass with partially defined contours, measuring 4.0 × 3.0 cm, with muscle infiltration. Histological examination revealed a malignant tumor. Radical mastectomy was then performed with clear surgical margins. The patient began chemotherapy with paclitaxel. Following the second cycle of chemotherapy, he presented with headache and seizures due to a frontal lobe metastasis. Twenty days after the onset of neurological symptoms, the patient died. Conclusions Primary angiosarcomas of the male breast are extremely rare. This is the sixth case published in the literature. It is in agreement with other studies in the literature concerning clinical presentation and poor prognosis. Treatment consists in surgical removal of the tumor with clear margins and without axillary lymphadenectomy

PRODUÇÃO DE RECURSOS DIDÁTICOS NA EXTENSÃO: PROPOSTAS DE ENSINO DE CIÊNCIAS USANDO INSTRUMENTOS DIDÁTICOS

A obra Produção de Recursos Didáticos na Extensão: Propostas de Ensino de Ciências Usando Instrumentos Didáticos é produto de pesquisas e trabalhos desenvolvidos no curso de Licenciatura em Biologia da Universidade Federal de Tocantins (UFT), Câmpus de Araguaína, através dos projetos de extensão Futuros Cientistas – Vêm para a Biologia (Coordenadora Lidianne Salvatierra) e Feira de Ciências do Estado do Tocantins (Coordenador Gecilane Ferreira) que possuem como objetivos centrais e confluentes a aproximação de alunos e professores da Educação Básica com a comunidade acadêmica, o fomento do senso de investigação científica de alunos do Ensino Fundamental e Ensino Médio, e apresentação e captação de futuros acadêmicos para o curso de Biologia.Ambos os projetos de extensão são desenvolvidos no âmbito do curso de Biologia com a participação de escolas públicas de Araguaína e demais municípios próximos, e consiste no desenvolvimento de dinâmicas de simulação de pesquisa, onde estudantes da rede básica aprendem mais sobre o curso de Biologia e são convidados a participarem ativamente dos eventos da universidade ainda durante a Educação Básica. Os projetos são de caráter intermitente a fim de contribuir para a diminuição da distância entre a comunidade externa e interna.A presente obra foi pensada em duas partes com objetivos distintos, porém interligados. Uma parte (Parte I) foca nesta obra como um produto acadêmico a partir de projetos de extensão na forma de um material de apoio aos professores de Ciências e Biologia que necessitam criar seus próprios recursos didáticos, e é composta por uma coletânea de comunicações curtas de planejamentos de modelos didáticos de baixo custo. E a segunda parte (Parte II) apresenta artigos completos que abordam a utilização de maquetes didáticas no ensino a partir de diferentes pontos de vistas e outros relatos de experiências provenientes das ações dos projetos de extensão. A seguir cada parte é detalhada, comentada e contextualizada:A Parte I – Coletânea de Comunicações Curtas sobre Modelos Didáticos de Invertebrados apresenta uma série de comunicações curtas sobre o processo de planejamento e confecção de maquetes didáticas de baixo custo com foco no ensino de Zoologia dentro das habilidades EM13CNT202 da Base Nacional Comum Curricular. Todas as comunicações foram elaboradas a fim de que professores e alunos possam utilizar as ideias apresentadas aqui e replicá-las em suas instituições de ensino. Os extensionistas e demais alunos do curso foram incentivados a utilizarem materiaisrecicláveis ou com o menor custo possível sempre pensando na realidade socioeconômica da maioria dos estudantes da rede pública brasileira.A Parte II – Coletânea de Artigos sobre o Uso de Modelos Didáticos reuni seis artigos completos que foram produzidos a partir das experiências promovidas com o desenvolvimento dos projetos de extensão no âmbito da Universidade Federal do Tocantins em colaboração com a comunidade externa. Os artigos possuem caráter de investigação científica sobre o uso de modelos didáticos e também de relato de experiência