Uma experiência de Estudo de Aula em Matemática no Ensino Superior com estudantes de Engenharia

A Matemática é frequentemente referida como uma das causas de insucesso em cursos de engenharia. Focado na aprendizagem do aluno, o estudo de aula busca promover o desenvolvimento profissional docente por meio de um ambiente colaborativo e reflexivo e pode, portanto, ser uma forma de procurar estratégias de ensino que melhorem o desempenho dos estudantes. Este artigo apresenta uma experiência de estudo de aula, na qual procuramos perceber o impacto que a aula de investigação, com resolução de Problemas de Otimização, teve em alunos de Análise Matemática I, do curso de Engenharia Mecânica, de um Instituto Politécnico em Portugal. Discutimos se a abordagem utilizada motivou os estudantes no processo de aprendizagem. A pesquisa é qualitativa, de cunho interpretativo, com design de observação participante, tendo reunido duas professoras do referido Instituto e uma doutoranda em Didática da Matemática (docente em um Instituto Federal no Brasil) num estudo de aula com oito sessões gravadas em vídeo. Também foram objetos de análise os documentos elaborados pelas professoras e as respostas dos estudantes às tarefas propostas e a um questionário. Os resultados indicam a recorrência das seguintes dimensões nas ações dos alunos: trabalho em equipa, discussão em grupo, entusiasmo na execução das tarefas, adesão à abordagem implementada e aprendizagem mais ativa. Apesar de identificarmos algumas limitações na implementação do estudo de aula no ensino superior, concluímos que a experiência foi bastante positiva, no que diz respeito ao feedback dos alunos, pelo que esta pode ser uma forma de ajudar a motivá-los para a aprendizagem da Matemática.Mathematics is often referred to as one of the causes of failure in engineering courses. Focussed on student learning, lesson study promotes teacher professional development through a collaborative and reflective environment and can therefore be a way of looking for teaching strategies that improve student performance. This paper presents an experience of lesson study, in which we sought to understand the impact that the research lesson, with Optimization problem solving, had on Mathematical Analysis I students on the Mechanical Engineering course at a Polytechnic Institute in Portugal. We discuss whether the developed approach motivated students in the learning process. The methodology research is qualitative with an interpretative paradigm, with a participant observation design, bringing together two teachers from the Institute and a PhD student in Mathematics Didactics (a teacher at a Federal Institute in Brazil) in a lesson study with eight video-recorded sessions. The documents produced by teachers and students' answers to a questionnaire were also analyzed.  We found that the students collaborated in the experiment and showed enthusiasm in carrying out the tasks during the collaborative teamwork. They reflected, questioned and searched for answers within the group. Although there were some limitations in implementing lesson study in higher education, we conclude that the experience was very positive in terms of student feedback, so this could be a way to help motivate them to learn mathematics

Development of a on-line course about administration of medication

O estudo descreveu o desenvolvimento de um curso on-line sobre o processo da administração de medicamentos - vias. Para tanto se utilizou o World Wide Web Course Tools (WebCT), que é um software que fornece várias ferramentas a supervisores e acesso a estudantes providos de uma senha a diversos ambientes. O material do curso foi subdivido em oito tópicos ilustrados: administração de medicamentos por via oral, sublingual, via parenteral, intradérmica, subcutânea, intramuscular, endovenosa e aplicação tópica e instilação, além das questões para avaliação de conhecimentos. Uma amostra de alunos de graduação da Escola de Enfermagem de Ribeirão Preto - USP avaliou positivamente o curso. Pretende-se agora inseri-lo em disciplina curricular do ensino de graduação, como um recurso adicional à aprendizagem dos alunos.El estudio describe el desarrollo de un curso via internet sobre el proceso de administración de medicamentos - vias. Para tal fin se utilizó el World Wide Web Course Tools (WebCT), que es un software que proporciona varias herramientas a supervisores y acceso a estudiantes, provistos de una clave, a diversos ambientes. El material del curso fue subdividido en ocho tópicos ilustrados: administración de medicamentos por via oral, sub-lingual, via parenteral, intradérmica, subcutánea, intramuscular, endovenosa y aplicación tópica e instilación, contiene además preguntas para la evaluación de conocimientos. Una muestra de alumnos del pre grado de la Escuela de Enfermería de Ribeirão Preto - USP evaluó positivamente el curso. Ahora se pretende incluirlo en la disciplina curricular del pre grado, como un recurso adicional para el aprendizaje de los alumnos.The study describes the development of an on-line course on medication administration. The World Wide Web Course Tools (WebCT) that was used is software that provides various tools for supervisors and access to a number of environments for students who have a password. The course material is presented in a series of websites which are sub-divided into eight illustrated topics concerning medication administration routes, in addition to questions for knowledge assessment. A sample of undergraduate students at the University of São Paulo at Ribeirão Preto College of Nursing has positively evaluated the course. It is now intended to be included as curricular course in the undergraduate program as an additional resource for student learning

Kinship Analysis and Pedigree Reconstruction of a Natural Regenerated Cork Oak (Quercus suber) Population

Cork oak (Quercus suber L.) is a valuable forest species in the western Mediterranean Basin due to its ecological value and the production of cork (a renewable natural material). Cork quality depends on the genetic background and cork oak environment, which has long been recognized. As no cork oak genetic trials with pedigree information were available, the inference of the genetic relatedness between individuals from molecular markers can potentially be applied to natural populations. This work aimed to investigate the potential of performing kinship prediction and pedigree reconstruction by SNP genotyping a natural cork oak population. A total of 494 trees located in Portugal were genotyped with 8K SNPs. The raw SNP set was filtered differently, producing four SNP sets that were further filtered by missing data, genotype frequency, and minor allele frequency. For each set, an identity by descent (IBD) matrix was generated to perform the relationship prediction, revealing from 22,114 to 23,859 relationships. Familial categories from the first to the third degree were able to be assigned. The feasibility of SNP genotyping for future studies on the kinship analysis and pedigree reconstruction of cork oak populations was demonstrated. The information produced may be used in further breeding and conservation programs for cork oakinfo:eu-repo/semantics/publishedVersio

Qualidade de vida relacionada à saúde e sintomas depressivos de estudantes do curso de graduação em Enfermagem

This is a descriptive, cross-sectional study aimed at investigating the health-related quality of life (HRQoL) of nursing students and its relationship with year of training, sociodemographic variables and the intensity of depressive symptoms. A convenience sample of 256 students, out of 353 eligible (72%), responded to the Medical Outcomes Study - The 36 Item Short-Form Health Survey (SF-36) and the Beck Depression Inventory (BDI) (self-administered). Final-year students, females and students with a higher intensity of depressive symptoms presented lower SF-36 scores in the physical functioning, vitality and social functioning domains. Institutional psychopedagogic support programs may minimize this negative impact on the HRQoL and encourage better professional performance of students in higher vulnerability situations.Se trata de un estudio descriptivo y transversal que investigó la calidad de vida relacionada a la salud (CVRS) de los estudiantes de enfermería y la relación con años de estudio, las variables sociodemográficas y la intensidad de los síntomas depresivos. Una muestra accidental de 256 estudiantes de 353 elegibles (72%) respondió el Medical Outcomes Study - The 36 Item Short-Form Health Survey (SF-36) y el Inventario de Depresión de Beck (IDB) (auto-aplicación). Estudiantes del último año del curso, los del sexo femenino y con mayor intensidad de síntomas depresivos, presentaron menores puntuaciones del SF-36 en los dominios capacidad funcional, vitalidad y aspectos sociales. El impacto es mayor en el último año del curso, los estudiantes de sexo femenino o con síntomas depresivos. Programas de apoyo psicológico podrían minimizar este impacto y contribuir a una mejor formación y desempeño profesional de los estudiantes en situación de mayor vulnerabilidad.Trata-se de estudo descritivo e transversal, que investigou a qualidade de vida relacionada à saúde (QVRS) de estudantes de Enfermagem e a relação da QVRS com o ano de estudo, as variáveis sociodemográficas e a intensidade de sintomas depressivos. Uma amostra acidental de 256 estudantes dos 353 elegíveis (72%) respondeu ao Medical Outcomes Study - The 36 Item Short-Form Health Survey (SF-36) e ao Inventário de Depressão de Beck (IDB). Estudantes do último ano do curso, sobretudo do sexo feminino e com maior intensidade de sintomas depressivos, apresentaram menores escores do SF-36 nos domínios capacidade funcional, vitalidade e aspectos sociais. O prejuízo na QVRS ocorre sobretudo no último ano do curso, nos estudantes do sexo feminino ou com sintomas depressivos. Programas institucionais de aconselhamento psicopedagógico poderiam minimizar o impacto negativo detectado na QVRS e contribuir para melhor formação e desempenho profissional dos estudantes em situação de maior vulnerabilidade

Mycobacterium marinum infection simulating chromomycosis: a case report

Skins infections caused by Mycobacterium marinum occur only rarely. We report one case of chronic and extensive M. marinum cutaneous infection simulating chromoblastomycosis and review the pertinent literature. A 52-year-old farmer reported a 32-year chronic skin problem on his right lower limb, resulting from contact with cacti. It consisted of skin lesion presenting with dyschromic atrophic center plate and verrucous borders with hematic crusts, extending from the knee anteriorly to the inferior third of the right leg. Mycobacterium marinum infection was detected by histopathological examination of a skin fragment, culture for mycobacteria and genetic mapping of the culture material. The patient was successfully treated with Ethambutol, Rifampicin and Trimethoprim-Sulfamethoxazole. The clinical and histopathological findings of M. marinum infection is nonspecific showing clinical polymorphism and bacilli are rarely evident on histopathological examination. Given these difficulties, it is essential to perform tissue culture in a suspicious case and it is important keep this infection in mind in patients with long-lasting indolent verrucous lesions and a history of exposure to sea water, freshwater, aquaria or fish

Isolation, absolute configuration and cytotoxic activities of alkaloids from Hippeastrum goianum (Ravenna) Meerow (Amaryllidaceae)

The phytochemical study of Hippeastrum goianum led to the identification of 13 compounds by means of gas chromatography-mass spectrometry (GC-MS) and nuclear magnetic resonance (NMR). Compounds 7-demethoxy-9-O-methylhostasine (1) and 7-deoxi-trans-dihydronarciclasine (2) had their absolute configurations determined by vibrational circular dichroism (VCD). This is the first time that compound 1 is described in the Amaryllidaceae family. The cytotoxicity of all isolated compounds was tested against colorectal carcinoma (HCT 116), breast carcinoma (MCF-7), and non-tumor human retinal pigment epithelium (RPE) cell lines. The half-maximum inhibitory concentration (IC50) of compound 2 against each cell line was equivalent to the positive control (doxorubicin), indicating a considerable cytotoxic activity. Keywords: narciclasine; galasine; cytotoxic activity; absolute configuration; vibrational circular dichrois

The GO-DACT protocol : a multicentre, randomized, double-blind, parallel-group study to compare the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy

© 2001-2020 Sociedade Portuguesa de ReumatologiaThe GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 24 weeks. Both clinical (dactylitis severity score and the Leeds dactylitis index) and imaging (high resolution magnetic resonance imaging), among others, were assessed as outcomes. The main objective of GO-DACT is to provide evidence to improve the treatment algorithm and care of psoriatic arthritis patients with active dactylitis. In this manuscript we describe the GO-DACT protocol and general concepts of the methodology of this trial.info:eu-repo/semantics/publishedVersio

Complicações Pós-Trauma: Gerenciando Edema Cerebral e Hipertensão Intracraniana

Introduction: The interconnection between cerebral edema and intracranial hypertension requires complex and rigorous monitoring, since cerebral edema directly influences the increase in intracranial pressure, resulting in a series of serious symptoms that can vary depending on the extent of the edema and other underlying factors. Objective: Understand complications arising from trauma and how to manage cerebral edema and intracranial pressure. Methodology: The Cochrane, Medline and Pubmed databases were used, searching for articles published between the years 2015 to 2023, in Portuguese or English. Conclusion: The treatment of these post-trauma conditions varies according to the clinical manifestations of each patient, therefore, obtaining an early diagnosis contributes to better monitoring and recovery.Introdução: A interconexão entre edema cerebral e hipertensão intracraniana aborda um acompanhamento complexo e rigoroso, uma vez que o edema cerebral influencia diretamente no aumento da pressão intracraniana, resultando em uma série de sintomas graves que podem variar dependendo da extensão do edema e de outros fatores subjacentes. Objetivo: Compreender as complicações decorrentes de traumas e como gerenciar o edema cerebral e a pressão intracraniana.  Metodologia: Foram utilizadas as bases de dados Cochrane, Medline e Pubmed, buscando artigos publicados entre os anos 2015 a 2023, nos idiomas Português ou Inglês. Conclusão: O tratamento dessas condições pós-trauma varia de acordo com o as manifestações clínicas de cada paciente, por isso, obter o diagnóstico precoce contribui para um melhor monitoramento e recuperação