Relações entre percepção corporal, autoconceito e traços depressivos em crianças escolares com e sem excesso de peso

Ainda é controversa a existência de associações entre construtos psicológicos e estados nutricionais. O presente trabalho teve por objetivo verificar as relações entre autoconceito, traços depressivos, satisfação e percepção corporal entre crianças com e sem excesso de peso. Participaram do estudo 45 meninos e 34 meninas entre 7 e 12 anos (Média=9,33, DP=1,46) de uma escola pública, que responderam ao Questionário Sociodemográfico e Corporal, à Escala Piers-Harris de Autoconceito, à Children’s Figure Rating Scale, ao Inventário de Depressão Infantil (CDI) e tiveram seu peso e altura aferidos. Os resultados não apontaram associações entre o autoconceito e traços depressivos com o estado nutricional, mas sim com a percepção e satisfação corporal. Crianças com peso normal e excesso de peso não apresentaram diferença na percepção do estado nutricional. Dessa forma, traços depressivos e autoconceito parecem estar mais associados à percepção e insatisfação com o corpo do que com o estado nutricional

A connexin/ifi30 pathway bridges HSCs with their niche to dampen oxidative stress

Reactive oxygen species (ROS) represent a by-product of metabolism and their excess is toxic for hematopoietic stem and progenitor cells (HSPCs). During embryogenesis, a small number of HSPCs are produced from the hemogenic endothelium, before they colonize a transient organ where they expand, for example the fetal liver in mammals. In this study, we use zebrafish to understand the molecular mechanisms that are important in the caudal hematopoietic tissue (equivalent to the mammalian fetal liver) to promote HSPC expansion. High levels of ROS are deleterious for HSPCs in this niche, however this is rescued by addition of antioxidants. We show that Cx41.8 is important to lower ROS levels in HSPCs. We also demonstrate a new role for ifi30, known to be involved in the immune response. In the hematopoietic niche, Ifi30 can recycle oxidized glutathione to allow HSPCs to dampen their levels of ROS, a role that could be conserved in human fetal liver

Comunidade de pequenos mamíferos de paisagens nativas e pastagens cultivadas no Pantanal da Nhecolândia.

O Pantanal possui uma grande diversidade de habitats, compondo uma paisagem complexa que tem sido conservada pela pecuária tradicional. Mais recentemente, a implantação de pastagem cultivada, visando ao aumento da produtividade e intensificando o sistema de produção vem alterando a paisagem pantaneira. Os resultados dessa alteração é a simplificação da composição e da complexidade da paisagem, colocando em risco a biodiversidade regional. O objetivo deste estudo foi avaliar alterações na comunidade de pequenos mamíferos em diferentes fitofisionomias, inclusive área alterada, em duas Fazendas no Pantanal da Nhecolândia. The Pantanal presents a great habitat diversity composing a complex landscape which has been conserved by the traditional cattle ranching. Recently, the cultivation of pastures aiming the increase of the productivity and intensification of the production system has been altering the landscape in the Pantanal. The results of this alteration é the simplification of the landscape composition and complexity, placing at risk the regional biodiversity. The objective of this study was to evaluate the changes in the small mammal communities at different phytophysiognomies, including modified areas, in two ranches at the Nhecolândia region of the Pantanal

A Joint Venture of Ab Initio Molecular Dynamics, Coupled Cluster Electronic Structure Methods, and Liquid-State Theory to Compute Accurate Isotropic Hyperfine Constants of Nitroxide Probes in Water

The isotropic hyperfine coupling constant (HFCC, Aiso) of a pH-sensitive spin probe in a solution, HMI (2,2,3,4,5,5-hexamethylimidazolidin-1-oxyl, C9H19N2O) in water, is computed using an ensemble of state-of-the-art computational techniques and is gauged against X-band continuous wave electron paramagnetic resonance (EPR) measurement spectra at room temperature. Fundamentally, the investigation aims to delineate the cutting edge of current first-principles-based calculations of EPR parameters in aqueous solutions based on using rigorous statistical mechanics combined with correlated electronic structure techniques. In particular, the impact of solvation is described by exploiting fully atomistic, RISM integral equation, and implicit solvation approaches as offered by ab initio molecular dynamics (AIMD) of the periodic bulk solution (using the spin-polarized revPBE0-D3 hybrid functional), embedded cluster reference interaction site model integral equation theory (EC-RISM), and polarizable continuum embedding (using CPCM) of microsolvated complexes, respectively. HFCCs are obtained from efficient coupled cluster calculations (using open-shell DLPNO-CCSD theory) as well as from hybrid density functional theory (using revPBE0-D3). Re-solvation of “vertically desolvated” spin probe configuration snapshots by EC-RISM embedding is shown to provide significantly improved results compared to CPCM since only the former captures the inherent structural heterogeneity of the solvent close to the spin probe. The average values of the Aiso parameter obtained based on configurational statistics using explicit water within AIMD and from EC-RISM solvation are found to be satisfactorily close. Using either such explicit or RISM solvation in conjunction with DLPNO-CCSD calculations of the HFCCs provides an average Aiso parameter for HMI in aqueous solution at 300 K and 1 bar that is in good agreement with the experimentally determined one. The developed computational strategy is general in the sense that it can be readily applied to other spin probes of similar molecular complexity, to aqueous solutions beyond ambient conditions, as well as to other solvents in the longer run

Anthocyanin composition of young red wine cv. Ruby Cabernet and Syrah: effect of time and storage conditions.

The aim of this study was to evaluate the evolution of anthocyanins in red wines for 12 months of storage in bottles in two different conditions. The wine samples cv. Ruby Cabernet and cv. Syrah (Vitis vinifera L.) used for this study were produced in the Sub-middle São Francisco Valley, in the Northeast Region of Brazil, during the 2013 harvest

Anthocyanin composition of young red wine cv. Ruby Cabernet and Syrah: effect of time and storage conditions.

The aim of this study was to evaluate the evolution of anthocyanins in red wines for 12 months of storage in bottles in two different conditions. The wine samples cv. Ruby Cabernet and cv. Syrah (Vitis vinifera L.) used for this study were produced in the Sub-middle São Francisco Valley, in the Northeast Region of Brazil, during the 2013 harvest

PLANEJAMENTO TRIBUTÁRIO NUMA EMPRESA DE COMÉRCIO DE INSUMOS AGRÍCOLAS: UM ESTUDO DE CASO

Um correto planejamento tributário depende de uma contabilidade fidedigna, ou seja,a mesma deve seguir as normas e princípios contábeis normalmente aceitos.Dessa forma o presente trabalho é um estudo de caso de planejamento tributário,realizado na empresa Boa Colheita Ltda. Através da pesquisa bibliográfica,procurou-se atender o objetivo do estudo, que era buscar a melhor forma detributação do imposto de renda e contribuição social sobre o lucro líquido para aempresa. Durante o estudo, foram levantados dados junto à empresa, como as suasreceitas auferidas, os custos e despesas incorridos, através das suasdemonstrações contábeis. Após o levantamento dos dados, foram efetuados oscálculos dos impostos seja pelo Lucro Real ou pelo Lucro Presumido

Phenolic compounds, organic acids and antioxidant activity of grape juices produced from new Brazilian varieties planted in the Northeast Region of Brazil.

The phenolic compounds, organic acids and the antioxidant activity were determined for grape juice samples from new Brazilian varieties grown in the Sub-middle São Francisco Valley in the Northeast Region of Brazil. The results showed that the Brazilian grape juices have high antioxidant activity, which was significantly correlated with the phenolic compounds catechin, epicatechin gallate, procyanidin B1, rutin, gallic acid, caffeic acid, p-coumaric acid, pelargonidin-3-glucoside, cyanidin-3-glucoside, cyaniding-3,5-diglucoside and delphinidin-3-glucoside. The produced juice samples showed higher concentrations of trans-resveratrol than those observed in juices made from different varieties of grapes from traditional growing regions. Organic acids concentrations were similar to those of juices produced from other classical varieties. It was demonstrated that it is possible to prepare juices from grapes of new varieties grown in the Northeast of Brazil containing a high content of bioactive compounds and typical characteristics of the tropical viticulture practised in the Sub-middle São Francisco Valley