6,861 research outputs found
Effects of Anisotropy in QED3 from Dyson-Schwinger equations in a box
We investigate the effect of anisotropies in the fermion velocities of 2+1
dimensional QED on the critical number N_f^c of fermions for dynamical mass
generation. Our framework are the Dyson-Schwinger equations for the gauge boson
and fermion propagators formulated in a finite volume. In contrast to previous
Dyson-Schwinger studies we do not rely on an expansion in small anisotropies
but keep the full velocity dependence of fermion equations intact. As result we
find sizable variations of N_f^c away from the isotropic point in agreement
with other approaches. We discuss the relevance of our findings for models of
high-T_c superconductors.Comment: 9 pages, 7 figures, v2: minor changes, typos corrected, version
accepted by PR
The parameterized complexity of positional games
We study the parameterized complexity of several positional games. Our main result is that Short Generalized Hex is W[1]-complete parameterized by the number of moves. This solves an open problem from Downey and Fellows’ influential list of open problems from 1999. Previously, the problem was thought of as a natural candidate for AW[*]-completeness. Our main tool is a new fragment of first-order logic where universally quantified variables only occur in inequalities. We show that model-checking on arbitrary relational structures for a formula in this fragment is W[1]-complete when parameterized by formula size. We also consider a general framework where a positional game is represented as a hypergraph and two players alternately pick vertices. In a Maker-Maker game, the first player to have picked all the vertices of some hyperedge wins the game. In a Maker-Breaker game, the first player wins if she picks all the vertices of some hyperedge, and the second player wins otherwise. In an Enforcer-Avoider game, the first player wins if the second player picks all the vertices of some hyperedge, and the second player wins otherwise. Short Maker-Maker, Short Maker-Breaker, and Short Enforcer-Avoider are respectively AW[*]-, W[1]-, and co-W[1]-complete parameterized by the number of moves. This suggests a rough parameterized complexity categorization into positional games that are complete for the first level of the W-hierarchy when the winning condition only depends on which vertices one player has been able to pick, but AW[*]-complete when it depends on which vertices both players have picked. However, some positional games with highly structured board and winning configurations are fixed-parameter tractable. We give another example of such a game, Short k-Connect, which is fixed-parameter tractable when parameterized by the number of moves
Benign Bilateral Adenomyoepithelioma of the Mammary Gland in a Ring-tailed Lemur (Lemur catta)
Naturally occurring mammary tumours are uncommon in prosimians. A 20-year-old female ring-tailed lemur (Lemur catta) developed bilateral enlargement of the mammary glands. Surgical removal revealed that both masses were comprised of multiple nodules and cystic areas that entirely replaced the normal glands. Histologically, a benign neoplastic biphasic cellular proliferation, composed of luminal–epithelial and basal–myoepithelial components, was identified. Immunohistochemical analysis for expression of cytokeratin (CK) AE1/AE3, CK7, CK5 + 8, CK14, vimentin, p63 and 14-3-3σ highlighted the biphasic nature of the neoplasm. A low mitotic count, low Ki67 labelling index, expression of oestrogen receptor-α, lack of expression of human epidermal growth factor receptor and a 3-year disease-free period without recurrence supported the benign nature of the tumour. Macroscopically, histologically and immunohistochemically this neoplasm resembled benign adenomyoepithelioma of the breast in women. This is the first complete report of a naturally occurring mammary tumour in a ring-tailed lemur
Diagnosis of anaplastic large-cell lymphoma in a dog using CD30 immunohistochemistry
Anaplastic large-cell lymphoma or null-cell lymphoma is a clinical entity reported in people, classified according to the unique appearance of large pleomorphic cells that express CD30. Null-cell lymphoma has also been described in dogs when neither CD3 nor CD79α is expressed by the tumor. We describe a case of lymphoma in the dog in which neoplastic cells did not express routine B- or T-lymphocyte markers on flow cytometry or immunohistochemistry; however, cells immunohistochemically labeled for CD30. The dog in our case died 5 mo after initial presentation, confirming a poor prognosis. Identification of further similar cases in dogs would provide additional prognostic information for this subset of lymphomas. CD30 may also serve as a potential therapeutic target in anaplastic large-cell lymphomas
SINFONI in the Galactic Center: young stars and IR flares in the central light month
We report 75 milli-arcsec resolution, near-IR imaging spectroscopy within the
central 30 light days of the Galactic Center [...]. To a limiting magnitude of
K~16, 9 of 10 stars in the central 0.4 arcsec, and 13 of 17 stars out to 0.7
arcsec from the central black hole have spectral properties of B0-B9, main
sequence stars. [...] all brighter early type stars have normal rotation
velocities, similar to solar neighborhood stars. We [...] derive improved 3d
stellar orbits for six of these S-stars in the central 0.5 arcsec. Their
orientations in space appear random. Their orbital planes are not co-aligned
with those of the two disks of massive young stars 1-10 arcsec from SgrA*. We
can thus exclude [...] that the S-stars as a group inhabit the inner regions of
these disks. They also cannot have been located/formed in these disks [...].
[...] we conclude that the S-stars were most likely brought into the central
light month by strong individual scattering events. The updated estimate of
distance to the Galactic center from the S2 orbit fit is Ro = 7.62 +/- 0.32
kpc, resulting in a central mass value of 3.61 +/- 0.32 x 10^6 Msun. We
happened to catch two smaller flaring events from SgrA* [...]. The 1.7-2.45 mum
spectral energy distributions of these flares are fit by a featureless, red
power law [...]. The observed spectral slope is in good agreement with
synchrotron models in which the infrared emission comes from [...] radiative
inefficient accretion flow in the central R~10 Rs region.Comment: 50 pages, 10 figures, 2 tables, submitted to ApJ, February 6th, 2005,
abstract abridge
Finding consensus without computation
A canonical problem for swarms of agents is to collectively choose one of multiple options in their environment. We present a novel control strategy for solving this problem-the first to be free of arithmetic computation. The agents do not communicate with each other nor do they store run-time information. They have a line-of-sight sensor that extracts one ternary digit of information from the environment. At every time step, they directly map this information onto constant-value motor commands. We evaluate the control strategy with both simulated and physical e-puck robots. By default, the robots are expected to choose, and move to, one of two options of equal value. The simulation studies show that the strategy is robust against sensory noise, scalable to large swarm sizes, and generalizes to the problems of choosing between more than two options or between unequal options. The experiments-50 trials conducted with a group of 20 e-puck robots-show that the group achieves consensus in 96% of the trials. Given the extremely low hardware requirements of the strategy, it opens up new possibilities for the design of swarms of robots that are small in size (≪10 -3 m) and large in numbers (≫10 3 )
Extrafine beclomethasone/formoterol in severe COPD patients with history of exacerbations
The FORWARD study is a randomised, double-blind trial that compares the efficacy and safety of 48 weeks treatment with extrafine beclomethasone dipropionate/formoterol fumarate (BDP/FOR), 100/6 μg pMDI, 2 inhalations BID, vs. FOR 12 μg pMDI, 1 inhalation BID, in severe COPD patients with a history of exacerbations. Co-primary endpoints were exacerbation rate over 48 weeks and pre-dose morning FEV1 at 12 weeks. The ITT population included 1186 patients (69% males, mean age 64 years) with severe airflow limitation (mean post-bronchodilator FEV1 42% predicted). Salbutamol as rescue therapy, theophylline and tiotropium (if stable regimen prior to screening) were allowed. Compared to FOR, BDP/FOR: (1) reduced the exacerbation rate (rate ratio: 0.72 [95% confidence interval 0.62–0.84], p < 0.001); (2) improved pre-dose morning FEV1 (mean difference: 0.069 L [0.043–0.095] p < 0.001); (3) prolonged the time to first exacerbation; (4) improved the SGRQ total score. The percentage of patients with adverse events was similar (52.1% with BDP/FOR and 49.2% with FOR). Pneumonia incidence was low, slightly higher with BDP/FOR (3.8%) than with FOR (1.8%). No difference for laboratory values, ECG or vital signs. Extrafine BDP/FOR significantly reduces the exacerbation rate and improves lung function of patients with severe COPD and history of exacerbations as compared to FOR alone
Radiated Ultrashort High-Power Electromagnetic Pulses Induce ATP Release in B16F10 Murine Melanoma Cells
Ultrawideband electromagnetic pulses with high amplitude and short duration are reported to affect several aspects of cell physiology. They are usually delivered to the living material through electrodes in small dedicated chambers. Here we showed, using a totally different experimental setup, that radiated EM pulses illuminating the living material through a specialized antenna (without any direct contact) are able to trigger a rapid release of ATP in cultured murine cells that was concomitant with a drop of intracellular AEC. Despite this rapid and strong response, we found that cell viability and clonogenicity were only slightly affected by the EMF exposure
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