Micro‐ornamentation patterns in different areas of the epidermis in the gecko Tarentola mauritanica reflect variations in the accumulation of corneous material in Oberhautchen cells

Micro-ornamentations characterize the surface of scales in lepidosaurians and are summarized in four main patterns, i.e., spi- nulated, lamellated, lamellate-dentate, and honeycomb, although variations of these patterns are present in different species. Although geckos are known to possess a spinulated pattern derived from the Oberhautchen layer, also other pattern variations of the spinulated micro-ornamentation are present such as those indicated as dendritic ramification, corneous belts, and small bare patches. The present study mainly describes the variation of micro-ornamentations present in scales of different skin regions in the Mediterranean gecko Tarentula mauritanica using scannig and transmission electron microscopy. The study reports that the accumulation of corneous material in Oberhautchen cells is not homogenous in different areas of body scales and, when mature, this process gives rise to different sculpturing on the epidermal surface generating not only spinulae but also transitional zones leading to the other main patterns. It is hypothesized that spinulae formation derives from the verti- cal and lateral symmetric growth of tubercolate, non-overlapped scales of geckos. Sparse areas also result smooth or with serpentine-ridges likely revealing the beta-layer located underneath and merged with the Oberhautchen. The eco-functional role of this variable micro-ornamentation in the skin of lizards however remains largely speculative

The genus <i>Acanthochitona</i> (Mollusca: Polylacophora) in the Mediterranean Sea: morphological and molecular data

En el presente trabajo se pretende resolver la confusa taxonomía de las especies mediterráneas de los quitones del género Acanthochitona a través de su estudio morfológico (observaciones al SEM de aestetes, rádula y cintura) y molecular (COI, 12S, ITS1). En ambos casos se confirma la validez de las tres especies Acanthochitona fascicularis, A. crinita y A. oblonga, las dos últimas consideradas previamente como sinónimas

A Method for Battery Sizing in Parallel P4 Mild Hybrid Electric Vehicles

This article deals with a sensitivity analysis concerning the influence that the capacity of the battery in a parallel hybrid powertrain has on the vehicle's energy regeneration. The architecture under analysis is constituted by an internal combustion engine (ICE), which provides traction to the front axle's wheels, and an electric motor powering the rear wheels. The energy management system (EMS) is based on a simple torque split strategy that distributes the driver's required torque between the front and rear machines as a function of battery and electric motor functional limitations (state of charge, temperatures, and maximum admissible currents). Together with the selected driving cycles, the central role played by the battery size in the overall vehicle recoverable energy is evaluated, while the influence of the powertrain limitations is highlighted, accounting both for uncertain parameters (e.g., initial state of charge [SoC 0]) and for tunable parameters (e.g., maximum electric traction vehicle speed). Therefore, a method of sizing the battery of a P4 mild hybrid electric vehicle (HEV), which allows the maximization of the braking energy recovery, is developed

A multi-purpose control and power electronic architecture for active magnetic actuators

This paper shows the results related with the design and implementation of a multi-purpose electronic architecture used to drive magnetic actuators by means of a three-phase independent-legs module in place of the commonly used H-bridge modules. The typical application is the magnetic actuators drive used in active magnetic bearings. The architecture is composed of a control unit with a floating point Digital Signal Processor (DSP), a power board with six independent phase legs and a carrier board to interconnect them. When more than one module is required by the application, the communication between them is guaranteed by means of CAN bus interconnection. The proposed system allows to drive two pairs of opposite electromagnets, such as those typically used to control active magnetic bearings. The study is motivated by the opportunity of reducing the amount of power and control electronic components resulting in a more straightforward, efficient and cost reduction design

Processor-in-the-loop architecture design and experimental validation for an autonomous racing vehicle

Self-driving vehicles have experienced an increase in research interest in the last decades. Nevertheless, fully autonomous vehicles are still far from being a common means of transport. This paper presents the design and experimental validation of a processor-in-the-loop (PIL) architecture for an autonomous sports car. The considered vehicle is an all-wheel drive full-electric single-seater prototype. The retained PIL architecture includes all the modules required for autonomous driving at system level: environment perception, trajectory planning, and control. Specifically, the perception pipeline exploits obstacle detection algorithms based on Artificial Intelligence (AI), and the trajectory planning is based on a modified Rapidly-exploring Random Tree (RRT) algorithm based on Dubins curves, while the vehicle is controlled via a Model Predictive Control (MPC) strategy. The considered PIL layout is implemented firstly using a low-cost card-sized computer for fast code verification purposes. Furthermore, the proposed PIL architecture is compared in terms of performance to an alternative PIL using high-performance real-time target computing machine. Both PIL architectures exploit User Datagram Protocol (UDP) protocol to properly communicate with a personal computer. The latter PIL architecture is validated in real-time using experimental data. Moreover, they are also validated with respect to the general autonomous pipeline that runs in parallel on the personal computer during numerical simulation

Affective Temperaments and Somatization Among Unipolar Depression Patients and Healthy Controls

Introduction Literature describes important comorbidity rates between somatization and mood disorders. Furthermore, there are data suggesting an association between affective temperament and somatization traits in healthy subjects. Objective In the present observational study, we investigated affective temperaments and somatization aspects in clinical and healthy samples. Aim The study focused on differences between unipolar depressive inpatients (DEP) and controls (C). Method We administered to 20 DEP and 20 C following questionnaires: Mini International Neuropsychiatric Interview (MINI), 17-item Self Rating Depression Scale (SDS), Hypomania check list 32(HCL-32), Self Rating Anxiety Scale (SAS), DCPR diagnostic criteria for psychosomatic research, Brief TEMPS-A, Modified Somatic Perception Questionnaire (MSPQ), Somatosensory Amplification Scale-SSAS. DEP and C were matched for age, sex and marital status. Result About temperaments, ANOVA showed that DEP were more cyclothymic (p Conclusion Our data suggest that DEP present an important affective temperamental dysregulation. Relative to somatization aspects, DEP show a greater vulnerability than C

Serum thyroglobulin and 131I whole body scan after recombinant human TSH stimulation in the follow-up of low-risk patients with differentiated thyroid cancer

OBJECTIVE: The 'standard' postoperative follow-up of patients with differentiated thyroid cancer (DTC) has been based upon serum thyroglobulin (Tg) measurement and (131)I whole body scan ((131)I-WBS) after thyroid hormone (T(4)) treatment withdrawal. However, (131)I-WBS sensitivity has been reported to be low. Thyroid hormone withdrawal, often associated with hypothyroidism-related side effects, may now be replaced by recombinant human thyroid stimulating hormone (rhTSH). The aim of our study was to evaluate the diagnostic accuracy of (131)I-WBS and serum Tg measurement obtained after rhTSH stimulation and of neck ultrasonography in the first follow-up of DTC patients. DESIGN: Ninety-nine consecutive patients previously treated with total thyroidectomy and (131)I ablation, with no uptake outside the thyroid bed on the post-ablative (131)I-WBS (low-risk patients) were enrolled. METHODS: Measurement of serum Tg and (131)I-WBS after rhTSH stimulation, and ultrasound examination (US) of the neck. RESULTS: rhTSH-stimulated Tg was 1 ng/ml (Tg+) in 21 patients, including 6 patients with Tg levels >5 ng/ml. (131)I-WBS was negative for persistent or recurrent disease in all patients (i.e. sensitivity = 0%). US identified lymph-node metastases (confirmed at surgery) in 4/6 (67%) patients with stimulated Tg levels >5 ng/ml, in 2/15 (13%) with Tg>1<5 ng/ml, and in 2/78 (3%) who were Tg-negative. CONCLUSIONS: (i) diagnostic (131)I-WBS performed after rhTSH stimulation is useless in the first follow-up of DTC patients; (ii) US may identify lymph node metastases even in patients with low or undetectable serum Tg levels

Cervical lymph node metastasis in high-grade transformation of head and neck adenoid cystic carcinoma: a collective international review

Adenoid cystic carcinoma (AdCC) is among the most common malignant tumors of the salivary glands. It is characterized by a prolonged clinical course, with frequent local recurrences, late onset of metastases and fatal outcome. High-grade transformation (HGT) is an uncommon phenomenon among salivary carcinomas and is associated with increased tumor aggressiveness. In AdCC with high-grade transformation (AdCC-HGT), the clinical course deviates from the natural history of AdCC. It tends to be accelerated, with a high propensity for lymph node metastasis. In order to shed light on this rare event and, in particular, on treatment implications, we undertook this review: searching for all published cases of AdCC-HGT. We conclude that it is mandatory to perform elective neck dissection in patients with AdCC-HGT, due to the high risk of lymph node metastases associated with transformation

New species of Epitoniidae (Gastropoda: Epitonioidea) from the Red Sea

A new species of Gregorioiscala Cossman, 1912 (Gastropoda: Epitoniidae) is described based on shells collected in the bathyal zone of the central Red Sea, off Sudan. Gregorioiscala federicoi n. sp. is the first representative of this bathyal genus in the Red Sea. Type specimens of Scala sumatrensis Thiele, 1925, Scala punctata Thiele, 1925, and Scala costigera Thiele, 1925 are illustrated