Evaluation of the Systemic and Regional Antibiotic Therapy Effectiveness as Part of Complex Therapy in Patients with Locally Spread Breast Cancer

In recent years, breast cancer is the most common oncologic pathology and the most common cause of disability among women in developed countries.The aim of the study. To improve direct and long-term results of treatment in patients with locally spread forms of breast cancer (LSBC) by accelerated regression of perifocal inflammatory changes using selective intraarterial application of antibiotics; improving patients' quality of life.Materials and methods. The main sample consisted of 109 patients.The control group included 65 (61 %) clinical cases of LSBC who were performed series of courses of intravenous systemic polychemotherapy (SPHT) as neoadjuvant therapy accompanied by systemic intravenous antibiotic therapy. The study group consisted of 42 (39 %) patients who were performed selective intraarterial neoadjuvant polychemotherapy course with simultaneous regional use of antibiotic therapy in the intraarterial administration.Results. The regional administration of antibiotics as a part of the complex neoadjuvant therapy, along with the method of selective intraarterial polychemotherapy, has a positive effect on the linear and chronometric regression of perifocal inflammatory changes around the focus of the primary inoperable LSBC, which positively affects the somatic and psychological patient's state and increases the quality of his life.Conclusions. The complex regional impact on the affected organ has a statistically confirmed better effect with bright holistic features, demonstrating the additive synergism of selective techniques.The selective intraarterial antibiotic therapy does not require additional time and material costs while increasing the efficiency of the method. The versatile advanced approach positively affects the somatic and psychological state of the patient

Evaluation of the systemic and regional antibiotic therapy effectiveness as part of complex therapy in patients with locally spread breast cancer

In recent years, breast cancer is the most common oncologic pathology and the most common cause of disability among women in developed countries. The aim of the study. To improve direct and long-term results of treatment in patients with locally spread forms of breast cancer (LSBC) by accelerated regression of perifocal inflammatory changes using selective intraarterial application of antibiotics; improving patients’ quality of life. The main sample consisted of 109 patients.The control group included 65 (61 %) clinical cases of LSBC who were performed series of courses of intravenous systemic polychemotherapy (SPHT) as neoadjuvant therapy accompanied by systemic intravenous antibiotic therapy. The study group consisted of 42 (39 %) patients who were performed selective intraarterial neoadjuvant polychemotherapy course with simultaneous regional use of antibiotic therapy in the intraarterial administration. The regional administration of antibiotics as a part of the complex neoadjuvant therapy, along with the method of selective intraarterial polychemotherapy, has a positive effect on the linear and chronometric regression of perifocal inflammatory changes around the focus of the primary inoperable LSBC, which positively affects the somatic and psychological patient’s state and increases the quality of his life. The complex regional impact on the affected organ has a statistically confrmed better effect with bright holistic features, demonstrating the additive synergism of selective techniques.The selective intraarterial antibiotic therapy does not require additional time and material costs while increasing the effciency of the method. The versatile advanced approach positively affects the somatic and psychological state of the patient

Хеджи в женском речевом поведении (на примере английского, русского и украинского языков)

The article sheds light on differences in quontitative and qualitative representation of hedges used by women-representatives of English, Russian and Ukrainian speech communities. The author demonstrated main functions of hedging in female speech and worked out the classification of means of expressing hedges in female speech behaviour in English, Russian and Ukrainian languages.В статье освещаются количественные и качественные различия репрезентации хеджей в речи женщин-представительниц английского, украинского и русского языковых сообществ. Автором выделены основные функции хеджей в женской речи и разработана классификация средств выражения хеджей в женском речевом поведении в английском, украинском и русском языках.В статті висвітлюються кількісні та якісні розбіжності репрезентації хеджів в мовленні жінок-представниць англійської, російської та української мовних спільнот. Автором виділені основні функції хеджів в жіночому мовленні та розроблено класифікацію засобів вираження хеджів на матеріалі жіночої мовленнєвої поведінки в англійській, українській та російській мовах

The training of verbal creativity with students of psychological speciality

The article defines the term verbal creativity, distinguishes its criteria, sheds light on its role in teaching a foreign language to future psychologists. It also suggests stages of verbal creativity training and a set of exercises in order to facilitate the development of students' communicative competence as a component of their professional competence

Сравнительная характеристика разделительных вопросов в женском речевом поведении (в английском, украинском и русском языках)

The article sheds light on isomorphic and allomorphic features of tags in female speech in English, Russian and Ukrainian languages. It also demonstrates the differences in functional distribution of tag questions in contrasted languages.Стаття висвітлює ізоморфні та аломорфні риси розділових питань у жіночій мовленнєвій поведінці в англійській, українській та російській мовах. Автор також демонструє відмінності у функціональній дистрибуції розділових питань у порівнюваних мовах.Статья освещает изоморфические и алломорфические черты разделительных вопросов в женском речевом поведении в английском, украинском и русском языках. Автор также демонстрирует отличия в функциональной дистрибуции разделительных вопросов в сравниваемых яхыках