2,022 research outputs found

    Post-AGB Stars in Globular Clusters and Galactic Halos

    Get PDF
    We discuss three aspects of post-AGB (PAGB) stars in old populations. (1) HST photometry of the nucleus of the planetary nebula (PN) K 648 in the globular cluster (GC) M15 implies a mass of 0.60 Msun, in contrast to the mean masses of white dwarfs in GCs of ~0.5 Msun. This suggests that K 648 is descended from a merged binary, and we infer that single Pop II stars do not produce visible PNe. (2) Yellow PAGB stars are the visually brightest stars in old populations (Mv ~ -3.3) and are easily recognizable because of their large Balmer jumps; thus they show great promise as a Pop II standard candle. Two yellow PAGB stars in the GC NGC 5986 have the same V magnitudes to within +/-0.05 mag, supporting an expected narrow luminosity function. (3) Using CCD photometry and a u filter lying below the Balmer jump, we have detected yellow PAGB stars in the halo of M31 and in its dwarf elliptical companion NGC 205. With the Milky Way zero point, we reproduce the Cepheid distance to M31, and find that NGC 205 is ~100 kpc further away than M31. The star counts imply a yellow PAGB lifetime of about 25,000 yr, and their luminosities imply masses near 0.53 Msun.Comment: 6 pages, 2 figures. To appear in proceedings of Torun, Poland, workshop on "Post-AGB Objects (Proto-Planetary Nebulae) as a Phase of Stellar Evolution," ed. S.K. Gorn

    Adiponectin protects against paraquat-induced lung injury by attenuating oxidative/nitrative stress.

    Get PDF
    The specific mechanisms underlying paraquat (PQ)-induced lung injury remain unknown, which limits understanding of its cytotoxic potential. Although oxidative stress has been established as an important mechanism underlying PQ toxicity, multiple antioxidants have proven ineffective in attenuating the deleterious effects of PQ. Adiponectin, which shows anti-oxidative and antinitrative effects, may have the potential to reduce PQ-mediated injury. The present study determined the protective action of globular domain adiponectin (gAd) on PQ-induced lung injury, and attempted to elucidate the underlying mechanism or mechanisms of action. BALB/c mice were administered PQ, with and without 12 or 36 h of gAd pre-treatment. The pulmonary oxidative/nitrative status was assessed by measuring pulmonary O2(‱-), superoxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO) and 8-hydroxy-2-dydeoxy guanosine (8-OHdG) production, and blood 3-Nitrotyrosine (3-NT). At a dose of 20 mg/kg, PQ markedly increased O2(‱-), SOD, MDA, NO and 8-OHdG production 3 h post-administration, but did not significantly increase 3-NT levels until 12 h. gAd inhibited these changes in a dose-dependent manner, via transient activation of MDA, followed by attenuation of MDA formation from 6 h onwards. Histological analysis demonstrated that gAd decreased interstitial edema and inflammatory cell infiltration. These results suggest that gAd protects against PQ-induced lung injury by mitigating oxidative/nitrative stress. Furthermore, gAd may be a potential therapeutic agent for PQ-induced lung injury, and further pharmacological studies are therefore warranted

    Microbial electrocatalysis with Geobacter sulfurreducens biofilm on stainless steel cathodes

    Get PDF
    Stainless steel and graphite electrodes were individually addressed and polarized at−0.60V vs. Ag/AgCl in reactors filled with a growth medium that contained 25mM fumarate as the electron acceptor and no electron donor, in order to force the microbial cells to use the electrode as electron source. When the reactor was inoculated with Geobacter sulfurreducens, the current increased and stabilized at average values around 0.75Am−2 for graphite and 20.5Am−2 for stainless steel. Cyclic voltammetry performed at the end of the experiment indicated that the reduction started at around −0.30V vs. Ag/AgCl on stainless steel. Removing the biofilm formed on the electrode surface made the current totally disappear, confirming that the G.sulfurreducens biofilm was fully responsible for the electrocatalysis of fumarate reduction. Similar current densities were recorded when the electrodes were polarized after being kept in open circuit for several days. The reasons for the bacteria presence and survival on non-connected stainless steel coupons were discussed. Chronoamperometry experiments performed at different potential values suggested that the biofilm-driven catalysis was controlled by electrochemical kinetics. The high current density obtained, quite close to the redox potential of the fumarate/succinate couple, presents stainless steel as a remarkable material to support biocathodes

    A quantum framework for likelihood ratios

    Get PDF
    The ability to calculate precise likelihood ratios is fundamental to many STEM areas, such as decision-making theory, biomedical science, and engineering. However, there is no assumption-free statistical methodology to achieve this. For instance, in the absence of data relating to covariate overlap, the widely used Bayes’ theorem either defaults to the marginal probability driven “naive Bayes’ classifier”, or requires the use of compensatory expectation-maximization techniques. Equally, the use of alternative statistical approaches, such as multivariate logistic regression, may be confounded by other axiomatic conditions, e.g., low levels of co-linearity. This article takes an information-theoretic approach in developing a new statistical formula for the calculation of likelihood ratios based on the principles of quantum entanglement. In doing so, it is argued that this quantum approach demonstrates: that the likelihood ratio is a real quality of statistical systems; that the naive Bayes’ classifier is a special case of a more general quantum mechanical expression; and that only a quantum mechanical approach can overcome the axiomatic limitations of classical statistics

    An extensive anoxic event in the Triassic of the South China Block : a pyrite framboid study form Dajiang and its implications for the cause(s) of oxygen depletion

    Get PDF
    Water column oxygen deficiency has been considered as a potent driver of the extinction of marine benthos, and is a main feature of marine environments in the aftermath of the end-Permian mass extinction. The record of Permian-Triassic anoxia is more complex than previously thought, and is seen to vary between different palaeogeographic settings, but a full understanding is hindered by a paucity of evidence. During the Permian-Triassic interval the South China Block was located equatorially with Palaeotethys to the north and western Panthalassa to the south. This specific configuration provides a unique opportunity to compare the extent and duration of oxygen deficiency in Palaeotethys and Panthalassa under broadly similar climatic conditions. Sedimentary facies and pyrite framboid size-frequency distributions suggest that the oxygen-poor conditions became widespread across the shallow-marine carbonate platform of the South China Block immediately above the Permian-Triassic boundary and mass extinction level. Oxygen deficiency was most intense at the southern margin of the block where it met Panthalassa. Proposed drivers of the expansion of oxygen minimum zones into platform settings include enhanced terrigenous input and/or ocean stratification, or alternatively the upwelling of nutrient-rich deep ocean water. The former mechanisms are theoretically more likely to have operated in the relatively restricted Palaeotethys which was surrounded by ancient lands. In contrast, Panthalassa would likely have experienced stronger oceanic circulation and therefore be more susceptible to the effects of upwelling. Although variations in the record of the South China Block anoxic event might reflect local factors, the greater intensity of oxygen deficiency and a concomitant larger negative shift in carbonate carbon isotopes on its Panthalassan margin point to a key role for upwelling. This mechanism was likely a major driver of the Permian-Triassic global oceanic anoxic event, which itself was at least partly responsible for the ongoing inhospitable conditions and delayed recovery following the end-Permian extinction

    The cooperative behaviour of antimicrobial peptides in model membranes

    Get PDF
    A systematic analysis of the hypothesis of the antimicrobial peptides' (AMPs) cooperative action is performed by means of full atomistic molecular dynamics simulations accompanied by circular dichroism experiments. Several AMPs from the aurein family (2.5,2.6, 3.1), have a similar sequence in the first ten amino acids, are investigated in different environments including aqueous solution, trifluoroethanol (TFE), palmitoyloleoylphosphatidylethanolamine (POPE), and palmitoyloleoylphosphatidylglycerol (POPG) lipid bilayers. It is found that the cooperative effect is stronger in aqueous solution and weaker in TFE. Moreover, in the presence of membranes, the cooperative effect plays an important role in the peptide/lipid bilayer interaction. The action of AMPs is a competition of the hydrophobic interactions between the side chains of the peptides and the hydrophobic region of lipid molecules, as well as the intra peptide interaction. The aureins 2.5-COOH and 2.6-COOH form a hydrophobic aggregate to minimize the interaction between the hydrophobic group and the water. Once that the peptides reach the water/lipid interface the hydrophobic aggregate becomes smaller and the peptides start to penetrate into the membrane. In contrast, aurein 3.1-COOH forms only a transient aggregate which disintegrates once the peptides reached the membrane, and it shows no cooperativity in membrane penetratio

    Cosmological Constraints on the Sign-Changeable Interactions

    Full text link
    Recently, Cai and Su [Phys. Rev. D {\bf 81}, 103514 (2010)] found that the sign of interaction QQ in the dark sector changed in the approximate redshift range of 0.45\,\lsim\, z\,\lsim\, 0.9, by using a model-independent method to deal with the observational data. In fact, this result raises a remarkable problem, since most of the familiar interactions cannot change their signs in the whole cosmic history. Motivated by the work of Cai and Su, we have proposed a new type of interaction in a previous work [H. Wei, Nucl. Phys. B {\bf 845}, 381 (2011)]. The key ingredient is the deceleration parameter qq in the interaction QQ, and hence the interaction QQ can change its sign when our universe changes from deceleration (q>0q>0) to acceleration (q<0q<0). In the present work, we consider the cosmological constraints on this new type of sign-changeable interactions, by using the latest observational data. We find that the cosmological constraints on the model parameters are fairly tight. In particular, the key parameter ÎČ\beta can be constrained to a narrow range.Comment: 15 pages, 1 table, 8 figures, revtex4; v2: published versio

    A Cretaceous origin for fire adaptations in the Cape flora

    Get PDF
    Fire has had a profound effect on the evolution of worldwide biotas. The Cape Floristic Region is one of the world's most species-rich regions, yet it is highly prone to recurrent fires and fire-adapted species contribute strongly to the overall flora. It is hypothesized that the current fire regimes in the Cape could be as old as 6-8 million years (My), while indirect evidence indicates that the onset of fire could have reached 18 million years ago (Ma). Here, we trace the origin of fire-dependent traits in two monocot families that are significant elements in the fire-prone Cape flora. Our analysis shows that fire-stimulated flowering originated in the Cape Haemodoraceae 81 Ma, while fire-stimulated germination arose in the African Restionaceae at least 70 Ma, implying that wildfires have been a significant force in the evolution of the Cape flora at least 60 My earlier than previous estimates. Our results provide strong evidence for the presence of fire adaptations in the Cape from the Cretaceous, leading to the extraordinary persistence of a fire-adapted flora in this biodiversity hotspot, and giving support to the hypothesis that Cretaceous fire was a global phenomenon that shaped the evolution of terrestrial floras

    A Cationic Diode Based on Asymmetric NafionÂź Film Deposits

    Get PDF
    A thin film of NafionÂź, of approximately 5 microm thickness, asymmetrically deposited onto a 6 microm thick film of poly(ethylene terephthalate) (PET) fabricated with a 5, 10, 20, or 40 microm microhole, is shown to exhibit prominent ionic diode behaviour involving cation charge carrier ("cationic diode"). The phenomenon is characterized via voltammetric, chronoamperometric, and impedance methods. Phenomenologically, current rectification effects are comparable to those observed in nano-cone devices where space-charge layer effects dominate. However, for microhole diodes a resistive, a limiting, and an over-limiting potential domain can be identified and concentration polarization in solution is shown to dominate in the closed state.</p

    Interacting agegraphic dark energy model in tachyon cosmology coupled to matter

    Get PDF
    Scalar-field dark energy models for tachyon fields are often regarded as an effective description of an underlying theory of dark energy. In this paper, we propose the agegraphic dark energy model in tachyon cosmology by interaction between the components of the dark sectors. In the formalism, the interaction term emerges from the tachyon field nonminimally coupled to the matter Lagrangian in the model rather than being inserted into the formalism as an external source. The model is constrained by the observational data. Based on the best fitted parameters in both original and new agegraphic dark energy scenarios, the model is tested by Sne Ia data. The tachyon potential and tachyon field are reconstructed and coincidence problem is revisited.Comment: 11 pages, 10 figures. Published in PLB (contains some changes in the text with respect to the first version); arXiv admin note: text overlap with arXiv:1106.2659 by same author
    • 

    corecore