THE STUDY OF POPULATION SATISFACTION WITH THE STATE OF THE MARKETS OF PRESCHOOL EDUCATION, ADDITIONAL EDUCATION OF CHILDREN

The article discusses the problems of implementing state policy in the field of school education and preschool sphere. The article analyzes the results of a sociological study on the example of the educational services market Leningrad region. The results of a sociological study allow us to identify certain shortcomings in the organization of public services at the municipal level of government. The article discusses such aspects of organizing a competitive environment in the field of education as the number of organizations in the market, the representation of organizations in the market, the quality of services, price and the choice of organization. The results of the study allow us to note that more than a third of respondents are satisfied with the quality of services, and the choice of organization, and pricing policy. At the same time, the majority of respondents express certain doubts about these indicators, which is expressed in a small amount of differences between negative and positive values. The results of the study allow us to state the relevance of research on the quality of the organization of the provision of services in the field of preschool education, additional education of children, the market of psychological and pedagogical support services for children with disabilities. Studies show the high importance that households in the Leningrad Region attach to the education sector. This study allows us to identify areas of managerial impact to local authorities regulating these services.Monitoring the state of the market for services in the field of school and preschool education makes it possible to identify problem organizations and directions for solving social and economic problems in the field of educational organization. The education sector for all modern states is an important political component, the accessibility and universality of education is a constitutional indicator of the status - “social”, “rule of law”. 

RESEARCH OF SATISFACTION OF POPULATION WITH THE STATUS OF SERVICES IN THE EDUCATION MARKET

The article discusses the problems of implementing state policy in the field of school education and preschool sphere. The article analyzes the results of a sociological study on the example of the educational services market Leningrad region. The results of a sociological study allow us to identify certain shortcomings in the organization of public services at the municipal level of government. The article discusses such aspects of organizing a competitive environment in the field of education as the number of organizations in the market, the representation of organizations in the market, the quality of services, price and the choice of organization. The results of the study allow us to note that more than a third of respondents are satisfied with the quality of services, and the choice of organization, and pricing policy. At the same time, the majority of respondents express certain doubts about these indicators, which is expressed in a small amount of differences between negative and positive values. The results of the study allow us to state the relevance of research on the quality of the organization of the provision of services in the field of preschool education, additional education of children, the market of psychological and pedagogical support services for children with disabilities. Studies show the high importance that households in the Leningrad Region attach to the education sector. This study allows us to identify areas of managerial impact to local authorities regulating these services. Monitoring the state of the market for services in the field of school and preschool education makes it possible to identify problem organizations and directions for solving social and economic problems in the field of educational organization. The education sector for all modern states is an important political component, the accessibility and universality of education is a constitutional indicator of the status - “social”, “rule of law”.

Гибридные войны и государственные стратегии: концептуализация понятий и подходов

The article is devoted to the analysis of different approaches to the definition of “a hybrid war”, the problems of expanding the area where the hybrid wars are conducted. The author concludes that the activity of the states in the construction of national security strategies is based on the necessity of diversification of the instruments and the methods of protecting the state interests, as well as pursuing interests in external policy. Network and information technologies used in the conditions of ongoing hybrid war may pose a threat to the object and the subject of political influence. The problem of hybrid wars requires a deeper methodological and theoretical reflection, justification, conceptualization of the approaches and methods of implementing national security strategies, it also requires the awareness of the external and internal political risk factors during the implementation of hybrid instruments during strategic operations.В статье анализируются подходы к определению понятия «гибридные войны», проблемы расширения зон ведения гибридных войн. В статье констатируется, что активность государств в построении национальных стратегий безопасности исходит из необходимости диверсификации инструментов и методов защиты государственных интересов, отстаивания внешнеполитических интересов. Сетевые и информационные технологии используемые в условиях ведения гибридной войны способны поставить под угрозу и объект и субъект политического воздействия. Проблематика гибридных войн нуждается в более глубоком методологическом и теоретическом обосновании, концептуализации подходов и методов реализации национальных стратегий безопасности, осознания внешнеполитических и внутриполитических рисков реализации гибридных инструментов ведения стратегических операций

Monetární politika za předpokladu behaviorálních očekávání: Empirická validace heuristického modelu

This work takes one of the most prominent behavioral New-Keynesian models from the shelf and estimates it via the simulated method of moments. The model exhibits a remarkably good ft to the auto- and cross-covariance pro- fles of the euro area macroeconomic time series, especially compared to the standard rational expectations model. This result corroborates the claim that central banks which implement strict infation targeting are better of reacting to the output gap, on top of infation. JEL Classifcation E52, E70, D84, C53 Keywords Behavioral macroeconomics, heterogeneous ex- pectations, New-Keynesian model, Heuristic Switching Model, simulated method of moments Title Monetary Policy Under Behavioral Expecta- tions: An Empirical Validation of the Heuristic Switching ModelTato práce se zabývá odhadem jednoho z nejvýznačnějších behaviorálních key- nesiánských modelů pomocí metody simulačnćh momentů. Behaviorální model ftuje kovarianční matici makroekonomických časových řad euro oblasti po- zoruhodně dobře, zvlášť v porovnání se standardním racionálním modelem. Tento výsledek podporuje tvrzení, že centrální banky, které se pečují o cen- ovou stabilitu, mohou dosáhnout tohoto cíle lépe, pokud budou reagovat nejen na infaci, ale i na mezeru výstupu. Klasifkace JEL E52, E70, D84, C53 Klíčová slova Behaviorální makroekonomie, heterogenní očekávání, nový keynesiánský model, heuri- stický model, metoda simulačních mo- mentů Název práce Monetární politika za předpokladu behav- iorálních očekávání: Empirická validace heurestického modeluInstitut ekonomických studiíInstitute of Economic StudiesFaculty of Social SciencesFakulta sociálních vě

MEANS AND METHODS OF PREVENTION AND CORRECTION OF DEVIANT BEHAVIOR OF ADOLESCENTS BY MEANS OF ART EDUCATION AND CULTURAL STUDIES

The article deals with the tasks of using art education in the process of organizing training. The research is devoted to the disclosure the pedagogical potential of art education. The research reveals the directions of art education and cultural studies based on theoretical analysis. The study reveals the effect of art education and cultural studies in the correction of deviant and delinquent behavior of young people and adolescents. The article summarizes the available means and techniques of art education, such as music, art, dance, theater and many others. The study analyzes the principles of choosing specific art forms in the educational process. The study demonstrates that book therapy techniques can be used not only as a preventive program, but also as an early intervention program and a program for correcting deviations. The article reveals the sequence of methodological steps when using the techniques of book therapy. The study of the use of techniques of art education and cultural studies in the correction of deviant and delinquent behavior reveals the effectiveness of the use of various genres of fine art. The creation of a work of art contributes to the socialization of the student, reveals the creative potential, contributes to the process of emotional and social comfort of the student. The analysis of the practices of educational organizations shows the importance of professional experience in the field of art education, demonstrates the discovery of the most effective in the aesthetic sense techniques of artistic processing of material Educational organizations make extensive use of dance art techniques. Musical activity allows adolescents to achieve a certain level of cheerfulness. This is recorded by experimental studies in various countries using music therapy techniques in the educational process. Dance practices are also used by educational organizations. Dance and movement therapy suppresses aggression, replaces destructive forms of behavior with socially adequate forms of expression and the development of alternative action strategies.

New data on aphyllophoroid fungi (Basidiomycota) in forest-steppe communities of the Lipetsk region, European Russia

The data on 150 species of aphyllophoroid fungi from the Lipetsk region, Central Russian Upland, European Russia, are presented. The annotated species list based on the herbarium collections (LE, OHHI) and observations in the Galichya Gora Nature Reserve and in the Oleniy Nature Park, including 53 newly identified species in the Lipetsk region, is provided. The species Acanthophysellum minor was registered for the first time in Russia. Athelia nivea and Vuilleminia megalospora were observed only for the second time in the whole country. New data on ecology and distribution of species, such as Ceratobasidium cornigerum, Fibrodontia gossypina, Lindtneria panphyliensis, Peniophora lilacea, Phanerochaete aculeata, Phellinus rhamni, Sistotrema alboluteum, Vararia ochroleuca, and Xylodon tuberculatus, little-known in European Russia, are reported

Прогулка 12 КУРОРТ И ПАРК

Walk 12 HEALTH RESORT AND PARKDevelopment Plan for the Northern Part of the Sverdlovsky District in IrkutskThe Glazkovsky Necropolis in Irkutsk: an Archaeological Monument of Global ImportanceSketch Design of Water and Health Complex on the Territory of the Park of the Paris Commune in IrkutskSketch of the Master Plan and Zoning of the Park of the Paris Commune in IrkutskThe Sports Axis of the Left Bank of Irkutsk. Reconstruction of the Sports Complex "Locomotive"Museum and Conservation Complex "Glazkovsky Necropolis"Прогулка 12 КУРОРТ И ПАРКПроект планировки Северной части Свердловского округа г. ИркутскаГлазковский некрополь в Иркутске: памятник археологии мирового значенияЭскизный проект водно-оздоровительного комплекса на территории парка имени Парижской коммуны в ИркутскеЭскиз генерального плана и зонирования парка имени Парижской коммуны в г. ИркутскеСпортивная ось левобережья Иркутска. Реконструкция спортивного комплекса «Локомотив»Музейно-консервационный комплекс «Глазковский некрополь

Single fluorescent protein-based Ca2+ sensors with increased dynamic range

<p>Abstract</p> <p>Background</p> <p>Genetically encoded sensors developed on the basis of green fluorescent protein (GFP)-like proteins are becoming more and more popular instruments for monitoring cellular analytes and enzyme activities in living cells and transgenic organisms. In particular, a number of Ca²⁺sensors have been developed, either based on FRET (Fluorescence Resonance Energy Transfer) changes between two GFP-mutants or on the change in fluorescence intensity of a single circularly permuted fluorescent protein (cpFP).</p> <p>Results</p> <p>Here we report significant progress on the development of the latter type of Ca²⁺sensors. Derived from the knowledge of previously reported cpFP-based sensors, we generated a set of cpFP-based indicators with different spectral properties and fluorescent responses to changes in Ca²⁺concentration. Two variants, named Case12 and Case16, were characterized by particular high brightness and superior dynamic range, up to 12-fold and 16.5-fold increase in green fluorescence between Ca²⁺-free and Ca²⁺-saturated forms. We demonstrated the high potential of these sensors on various examples, including monitoring of Ca²⁺response to a prolonged glutamate treatment in cortical neurons.</p> <p>Conclusion</p> <p>We believe that expanded dynamic range, high brightness and relatively high pH-stability should make Case12 and Case16 popular research tools both in scientific studies and high throughput screening assays.</p

Pharmacokinetics and pharmacodynamics of rebamipide. New possibilities of therapy: A review

The MedLine database contains 570 publications, including 71 randomized clinical trials and 6 meta-analyses on the rebamipide molecule in 2022. Indications for the use of rebamipide are gastric ulcer, chronic gastritis with hyperacidityin the acute stage, erosive gastritis, prevention of damage to the gastrointestinal mucosa while taking non-steroidal anti-inflammatory drugs, eradication of Helicobacter pylori. Currently trials are studying the efficacy and safety of the drug in gouty and rheumatoid arthritis, osteoarthritis, Sjgren's syndrome, bronchial asthma, vitiligo, atherosclerosis, diseases of the kidneys and liver; using in traumatology to accelerate bone regeneration; in ophthalmology to improve the regeneration of corneal epithelium; in oncology to reduce inflammatory changes in the oral mucosa after chemoradiotherapy. The review article is about the main pharmacokinetic and pharmacodynamic characteristics of rebamipide. A detailed understanding of pharmacodynamics and pharmacokinetics allows for individual selection of therapy based on the characteristics of the patient's body gender, age, comorbidities; choose the optimal route of administration and dosing regimen; predict adverse effects and drug interactions; be determined with new clinical indications

The fungal literature-based occurrence database in southern West Siberia (Russia)

The abstract presents the initiative to develop the Fungal Literature-based Occurrence Database for Southern West Siberia (FuSWS), which mobilizes occurrences of fungi from published literature (literature-based occurrences, Darwin Core MaterialCitation). The FuSWS database includes 28 fields describing species name, publication source, herbarium number (if exists), date of sampling or observation, locality information, vegetation, substrate, and others. The initiative on digitization of literature-based occurrence data started in the northern part of Western Siberia two years ago (Filippova et al. 2021a). The present project extends the initiative to the south and includes eight administrative regions (Sverdlovsk, Omsk, Kurgan, Tomsk, Novosibirsk, Kemerovo, Altay, and Gorny Altay). The area occupies the central to southern part of the West Siberian Plain. It extends for about 1.5 thousand km from the west to the east from the eastern slopes of the Ural Mountains to Yenisey River, and from north to south—about 1.3 thousand km. The total area equals about 1.2 million km2.Currently, the project is actively growing in spatial, collaboration and data accumulation terms. The working group of about 30 mycologists from 16 organizations dedicated to the digitization initiative was created as part of the Siberian Mycological Society (informal organization since 2019). They have created the most complete bibliographic list of mycology-related papers for the Southern West Siberia, including over 800 publications for the last two centuries (the earliest dated 1800). At abstract submission, the database had been populated with a total of about 10K records from about 100 sources. The dataset is uploaded to GBIF, where it is available for online search of species occurrences and/or download (Filippova et al. 2021b) Fig. 1. The project's page with the introduction, templates, bibliography list, video-presentations and written instructions is available at the website of the Siberian Mycological Society (https://sibmyco.org/literaturedatabase).The following protocol describes the digitization workflow in detail:The bibliography of related publications is compiled using Zotero bibliographic manager. Only published works (peer-reviewed papers, conference proceedings, PhD theses, monographs or book chapters) are selected. If possible, the sources are digitized and added to the library as PDF files. The template of the FuSWS database is made with Google Sheets, which allows simultaneous use by several specialists, in a common data format provided. The simple Microsoft Excel template is also available for the offline databasing. The Darwin Core standard is applied to the database field structure to accommodate the relevant information extracted from the publications.From the available bibliography of publications related to the region, only works with species occurrences are selected for the databasing purpose. The main source of occurrences is annotated species lists with exact localities of the records. However, different sorts of other species citations are also extracted, provided that they had the connection to any geography. All occurrences are georeferenced, either from the coordinates provided in the paper, or from the verbatim description of the field work locality. The georeferencing of the verbatim descriptions is made using Yandex or Google map services. Depending on the quality of georeference provided in publications, the uncertainty is estimated as follows: 1) the coordinate of a fruiting structure or a plot provided in the publication gives the uncertainty about 3-30 meters; 2) the coordinate of the field work locality provided in publication gives the uncertainty about 500 m to 5 km; 3) the report of the species presence in a particular region gives the centroid of the area with the uncertainty radius to include its borders.The locality names reported in Russian are translated to English and written in the «locality» field. Russian descriptions are reserved in the field «verbatimLocality» for accuracy.When possible, the «eventDate» is extracted from the annotation data. Whenever this information is absent, the date of the publication is used instead with the remarks in the «verbatimEventDate» field.The ecological features, habitat and substrate preferences are written in the «habitat» field and reserved in Russian.The original scientific names reported in publications are filled in the «originalNameUsage» field. Correction of spelling errors is made using the GBIF Species Matching tool. This tool is also used to create the additional fields of taxonomic hierarchy from species to kingdom, to fill in the «taxonRank» field and to synonymize according to the GBIF Backbone Taxonomy.To track the digitization process, a worksheet is maintained. Each bibliographic record has a series of fields to describe the digitization process and its results: the total number of extracted occurrence records, general description of the occurrence quality, presence of the observation date, details of georeferencing and the name of a person responsible for the digitization