Investigation by Digital Image Correlation of Mixed Mode I and II Fracture Behavior of Metallic IASCB Specimens with Additive Manufactured Crack-Like Notch

This work investigates the fracture behavior of maraging steel specimens manufactured by the selective laser sintering (SLS) technology, in which a crack-like notch (sharp notch) was directly produced during the additive manufacturing (AM) process. For the evaluation of the fracture toughness, the inclined asymmetrical semi-circular specimen subjected to three points loading (IASCB) was used, allowing to cover a wide variety of Mode I and II combinations. The effectiveness of manufacturing crack-like notches via the SLS technique in metals was evaluated by comparing the obtained experimental results with the ones obtained with pre-cracks induced by fatigue loading. The investigation was carried out by using the digital image correlation (DIC) technique, that allowed the evaluation of the full displacement fields around the crack tip. The displacement field was then used to compute the stress intensity factors (SIFs) for various combinations of Mode I and II, via a fitting technique which relies on the Williams\u2019 model for the displacement. The SIFs obtained in this way were compared to the results obtained with the conventional critical load method. The results showed that the discrepancy between the two methods reduces by ranging from Mode I to Mode II loading condition. Finally, the experimental SIFs obtained by the two methods were described by the mixed mode local stress criterium

Fatigue Response of As-Built DMLS Maraging Steel and Effects of Aging, Machining, and Peening Treatments

The main motivations for this study arise from the need for an assessment of the fatigue performance of DMLS-produced Maraging Steel MS1, when it is used in the \u201cas fabricated\u201d state. The literature indicates a lack of knowledge from this point of view; moreover, the great potentials of the additive process may be more and more incremented, if an easier and cheaper procedure could be used after the building stage. The topic has been tackled experimentally, investigating the impact of heat treatment, machining, and micro-shot-peening on the fatigue strength with respect to the \u201cas built state\u201d. The results indicate that heat treatment may improve the fatigue response, as an effect of the relaxation of the process-induced tensile residual stresses. Machining can also be effective, but it must be followed (not preceded) by shot-peening, to benefit from the compressive residual stress state generated by the latter. Moreover, heat treatment and machining are related by a strong positive interaction, meaning their effects are synergistically magnified when they are applied together. The experimental study has been completed by fractographic as well as micrographic analyses, investigating the impact of the heat treatment on the actual microstructure induced by the stacking process

Tailoring residual stress profile of Selective Laser Melted parts byLaser Shock Peening

The paper describes a new approach in controlling and tailoring residual stress profile of parts made by Selective Laser Melting (SLM). SLM parts are well known for the high tensile stresses in the as – built state in the surface or subsurface region. These stresses have a detrimental effect on the mechanical properties and especially on the fatigue life. Laser Shock Peening (LSP) as a surface treatment method was applied on SLM parts and residual stress measurements with the hole – drilling method were performed. Two different grades of stainless steel were used: a martensitic 15-5 precipitation hardenable PH1 and an austenitic 316L. Different LSP parameters were used, varying laser energy, shot overlap, laser spot size and treatments with and without an ablative medium. For both materials the as-built (AB) residual stress state was changed to a more beneficial compressive state. The value and the depth of the compressive stress was analyzed and showed a clear dependence on the LSP processing parameters. Application of LSP on SLM parts showed promising results, and a novel method that would combine these two processes is proposed. The use of LSP during the building phase of SLM as a “3D LSP” method would possibly give the advantage of further increasing the depth and volume of compressive residual stresses, and selectively treating key areas of the part, thereby further increasing fatigue life

Novel Aminoquinoline Derivatives Significantly Reduce Parasite Load in Leishmania infantum Infected Mice

In this Letter, a detailed analysis of 30 4-aminoquinoline-based compounds with regard to their potential as antileishmanial drugs has been carried out. Ten compounds demonstrated IC50 < 1 \u3bcM against promastigote stages of L. infantum and L. tropica, and five compounds showed IC50 < 1 \u3bcM against intramacrophage L. infantum amastigotes. Two compounds showed dose-dependent enhancement of NO and ROS production by bone marrow-derived macrophages and remarkable reduction of parasite load in vivo, with advantage of being short-term and orally active. To the best of our knowledge, this is the first example of 4-amino-7-chloroquinoline derivatives active in Leishmania infantum infected mice