Fostering Academic and Social Growth in a Primary Literacy Workshop Classroom: Restorying Students with Negative Reputations

In most classrooms, there are students who have academic, behavioral, and/or interpersonal challenges that can disrupt the classroom community. In some cases, these challenges can build momentum, leading to a negative reputation or “story” that can follow the student throughout school. This academic, yearlong case study focused on Mae Graham, an exemplary teacher, and the cases of two students who began second grade with negative behavioral, emotional, and academic reputations from previous years in school. We describe how Mae “restoried” the students through personalized instruction and attention, classroom structure and curriculum, and social interactions in the classroom. We base restorying on theory and research in social identification, effective teaching, culturally responsive/relevant pedagogy, and the ethic of care

Preliminary data on boulders at station 6, Apollo 17 landing site

A cluster of boulders at Station 6 (Apollo 17 landing site) consists of breccias derived from the North Massif. Three preliminary lithologic units were established, on the basis of photogeologic interpretations; all lithologies identified photogeologically were sampled. Breccia clasts and matrices studied petrographically and chemically fall into two groups by modal mineralogy: (1) low-K Fra Mauro or high basalt composition, consisting of 50-60% modal feldspar, approximately 45% orthopyroxene and 1-7% Fe-Ti oxide; (2) clasts consisting of highland basalt composition, consisting of 70% feldspar, 30% orthopyroxene and olivine and a trace of Fe-Ti oxide

Impact histories of Vesta and Vestoids inferred from howardites, eucrites and diogenites

The parent body of the howardites, eucrites and diogenites (HEDs) is thought to be asteroid (4) Vesta [1]. However, several eucrites have now been recognized, like NWA 011 and Ibitira, with major element compositions and mineralogy like normal eucrites but with different oxygen isotope compositions and minor element concentrations suggesting they are not from the same body [2, 3]. The discoveries of abnormal eucrites and V-type asteroids that are probably not from Vesta [see 4] raise the question whether the HEDs with normal oxygen isotopes are coming from Vesta [3]. To address this issue and understand more about the evolution of Vesta in preparation for the arrival of the Dawn spacecraft, we integrate fresh insights from Ar-Ar dating and oxygen isotope analyses of HEDs, radiometric dating of differentiated meteorites, as well as dynamical and astronomical studies of Vesta, the Vesta asteroid family (i.e., the Vestoids), and other V-type asteroids

Lysenin Channels as Sensors for Ions and Molecules

Lysenin is a pore-forming protein extracted from the earthworm Eisenia fetida, which inserts large conductance pores in artificial and natural lipid membranes containing sphingomyelin. Its cytolytic and hemolytic activity is rather indicative of a pore-forming toxin; however, lysenin channels present intricate regulatory features manifested as a reduction in conductance upon exposure to multivalent ions. Lysenin pores also present a large unobstructed channel, which enables the translocation of analytes, such as short DNA and peptide molecules, driven by electrochemical gradients. These important features of lysenin channels provide opportunities for using them as sensors for a large variety of applications. In this respect, this literature review is focused on investigations aimed at the potential use of lysenin channels as analytical tools. The described explorations include interactions with multivalent inorganic and organic cations, analyses on the reversibility of such interactions, insights into the regulation mechanisms of lysenin channels, interactions with purines, stochastic sensing of peptides and DNA molecules, and evidence of molecular translocation. Lysenin channels present themselves as versatile sensing platforms that exploit either intrinsic regulatory features or the changes in ionic currents elicited when molecules thread the conducting pathway, which may be further developed into analytical tools of high specificity and sensitivity or exploited for other scientific biotechnological applications

Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior

The RASopathy neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant genetic disorders. In NF1 patients, neurological issues may result from damaged myelin, and mice with a neurofibromin gene (Nf1) mutation show white matter (WM) defects including myelin decompaction. Using mouse genetics, we find that altered Nf1 gene-dose in mature oligodendrocytes results in progressive myelin defects and behavioral abnormalities mediated by aberrant Notch activation. Blocking Notch, upstream mitogen-activated protein kinase (MAPK), or nitric oxide signaling rescues myelin defects in hemizygous Nf1 mutants, and pharmacological gamma secretase inhibition rescues aberrant behavior with no effects in wild-type (WT) mice. Concomitant pathway inhibition rescues myelin abnormalities in homozygous mutants. Notch activation is also observed in Nf1+/− mouse brains, and cells containing active Notch are increased in NF1 patient WM. We thus identify Notch as an Nf1 effector regulating myelin structure and behavior in a RASopathy and suggest that inhibition of Notch signaling may be a therapeutic strategy for NF1

The probe beam linac in CTF3

JACoW web site http://accelconf.web.cern.ch/AccelConf/e06/The test facility CTF3, presently under construction at CERN within an international collaboration, is aimed at demonstrating the key feasibility issues of the multi-TeV linear collider CLIC. The objective of the probe beam linac is to "mimic" the main beam of CLIC in order to measure precisely the performances of the 30 GHz CLIC accelerating structures. In order to meet the required parameters of this 200 MeV probe beam, in terms of emittance, energy spread and bunch-length, the most advanced techniques have been considered: laser triggered photo-injector, velocity bunching, beam-loading compensation, RF pulse compression ... The final layout is described, and the selection criteria and the beam dynamics results are reviewed

Taking the pulse of Mars via dating of a plume-fed volcano

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. The attached file is the published version of the article

Terrorism, governmentality and the simulated city: the Boston Marathon bombing and the search for suspect two

This article examines the online circulation of a photograph of the immediate aftermath of the 2013 Boston Marathon bombings taken by David Green, a Boston Marathon runner. The photograph fortuitously captured an image of Dzhokhar Tsarnaev, the younger Tsarnaev brother, running from the scene. Initially, Tsarnaev went unnoticed by online message board users and FBI investigators – he was just another face in the urban crowd. However, after he was identified as suspect two, he emerged in the photograph as the figure of terror, the condensed embodiment of the spectacular attack, and thus as a spectre, a figure whose appearance in the archive of the past haunts the future. The author examines how this spectral emergence simultaneously reveals the attack terrorism launches against everyday mediations and how everyday mediations respond to terrorist spectacle. He argues that photography sustains vernacular practices that also support the practices of urban governmentality. Understanding urban governmentality thus requires attending to the urban archive of visual mediation in which the relationships between past and present, image and reality, and surveillance and spectacle are always contingent and open to revision