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Preliminary Interdependency Analysis (PIA): Method and tool support
Bridging Physics and Biology Teaching through Modeling
As the frontiers of biology become increasingly interdisciplinary, the
physics education community has engaged in ongoing efforts to make physics
classes more relevant to life sciences majors. These efforts are complicated by
the many apparent differences between these fields, including the types of
systems that each studies, the behavior of those systems, the kinds of
measurements that each makes, and the role of mathematics in each field.
Nonetheless, physics and biology are both sciences that rely on observations
and measurements to construct models of the natural world. In the present
theoretical article, we propose that efforts to bridge the teaching of these
two disciplines must emphasize shared scientific practices, particularly
scientific modeling. We define modeling using language common to both
disciplines and highlight how an understanding of the modeling process can help
reconcile apparent differences between the teaching of physics and biology. We
elaborate how models can be used for explanatory, predictive, and functional
purposes and present common models from each discipline demonstrating key
modeling principles. By framing interdisciplinary teaching in the context of
modeling, we aim to bridge physics and biology teaching and to equip students
with modeling competencies applicable across any scientific discipline.Comment: 10 pages, 2 figures, 3 table
W(h)ither the academy? An exploration of the role of university social work in shaping the future of social work in Europe
A controversial proposal to pilot the training of child protection social workers through an intensive work-based route in England is being supported and funded by the UK Government. Frontline, the brainchild of a former teacher, locates social work training within local authorities (‘the agency’) rather than university social work departments (‘the academy’) and has stimulated debate amongst social work academics about their role in shaping the direction of the profession. As a contribution to this debate, this paper explores the duality of social work education, which derives its knowledge from both the academic social sciences and the experience of practice within social work agencies. While social work education has traditionally been delivered by the academy, this paper also explores whether the delivery of training in the allied professions of probation and nursing by ‘the agency’ is equally effective. Finally, this paper explores the Helsinki model which achieves a synergy of ‘academy’ and ‘agency’. It suggests that there are alternative models of social work education, practice and research which avoid dichotomies between the ‘academy’ and the ‘agency’ and enable the profession to be shaped by both social work academics and practitioners
Professional Perspectives of Youth Justice Policy Implementation:Contextual and Coalface Challenges
© 2020 The Authors. The Howard Journal of Crime and Justice published by Howard League and John Wiley & Sons Ltd This article offers a multilayered analysis of the subjective perspectives and experiences of key youth justice stakeholders; exploring the inherent dynamism, contradiction, non-linearity, and contentiousness of youth justice policy implementation. We interrogate how professionals make sense and meaning of policy in the real world and how professional perspectives drive and shape their contributions to policy implementation nationally and locally. Contemporaneously, these analyses enable us to critically examine the caricatures, stereotypes, and assumptions that can (mis)inform common constructions, representations, and understandings of youth justice policy trajectories, including those relating to contextual stability, conceptual clarity, robust evidence bases, and purported foundations in stakeholder consensus
The psychological-type profile of clergywomen in ordained local ministry in the Church of England : pioneers or custodians?
This study employs psychological-type theory to compare the psychological profile of 144 clergywomen serving in ordained local ministry in the Church of England alongside the established profile of 237 professional mobile clergywomen serving in the Church of England published by Francis, Craig, Whinney, Tilley, and Slater. The data found no significant differences between these two groups of clergywomen in terms of orientations (introversion and extraversion) or in terms of the judging process (thinking and feeling). In terms of the perceiving process, there was a significantly higher proportion of sensing types among those serving in ordained local ministry (70% compared with 35%). In terms of the attitudes, there was a significantly higher proportion of judging types among those serving in ordained local ministry (83% compared with 65%). The combined sensing judging (SJ) temperament accounted for 65% of the clergywomen serving in ordained local ministry, compared with 29% of the clergywomen serving in professional mobile ministry in the earlier study. It is argued that the SJ temperament characterises a custodian style of ministry
Fast multipole networks
Two prerequisites for robotic multiagent systems are mobility and
communication. Fast multipole networks (FMNs) enable both ends within a unified
framework. FMNs can be organized very efficiently in a distributed way from
local information and are ideally suited for motion planning using artificial
potentials. We compare FMNs to conventional communication topologies, and find
that FMNs offer competitive communication performance (including higher network
efficiency per edge at marginal energy cost) in addition to advantages for
mobility
Investigation of glutathione S-transferase zeta and the development of sporadic breast cancer
BACKGROUND: Certain genes from the glutathione S-transferase superfamily have been associated with several cancer types. It was the objective of this study to determine whether alleles of the glutathione S-transferase zeta 1 (GSTZ1) gene are associated with the development of sporadic breast cancer. METHODS: DNA samples obtained from a Caucasian population affected by breast cancer and a control population, matched for age and ethnicity, were genotyped for a polymorphism of the GSTZ1 gene. After PCR, alleles were identified by restriction enzyme digestion and results analysed by chi-square and CLUMP analysis. RESULTS: Chi-squared analysis gave a χ(2) value of 4.77 (three degrees of freedom) with P = 0.19, and CLUMP analysis gave a T1 value of 9.02 with P = 0.45 for genotype frequencies and a T1 value of 4.77 with P = 0.19 for allele frequencies. CONCLUSION: Statistical analysis indicates that there is no association of the GSTZ1 variant and hence the gene does not appear to play a significant role in the development of sporadic breast cancer
Corporate governance and financial constraints on strategic turnarounds
The paper extends the Robbins and Pearce (1992) two-stage turnaround response model to include governance factors. In addition to the retrenchment and recovery, the paper proposes the addition of a realignment stage, referring specifically to the re-alignment of expectations of principal and agent groups. The realignment stage imposes a threshold that must be crossed before the retrenchment and hence recovery stage can be entered. Crossing this threshold is problematic to the extent that the interests of governance-stakeholder groups diverge in a crisis situation. The severity of the crisis impacts on the bases of strategy contingent asset valuation leading to the fragmentation of stakeholder interests. In some cases the consequence may be that management are prevented from carrying out turnarounds by governance constraints. The paper uses a case study to illustrate these dynamics, and like the Robbins and Pearce study, it focuses on the textile industry. A longitudinal approach is used to show the impact of the removal of governance constraints. The empirical evidence suggests that such financial constraints become less serious to the extent that there is a functioning market for corporate control. Building on governance research and turnaround literature, the paper also outlines the general case necessary and sufficient conditions for successful turnarounds
A phenomenological approach to the simulation of metabolism and proliferation dynamics of large tumour cell populations
A major goal of modern computational biology is to simulate the collective
behaviour of large cell populations starting from the intricate web of
molecular interactions occurring at the microscopic level. In this paper we
describe a simplified model of cell metabolism, growth and proliferation,
suitable for inclusion in a multicell simulator, now under development
(Chignola R and Milotti E 2004 Physica A 338 261-6). Nutrients regulate the
proliferation dynamics of tumor cells which adapt their behaviour to respond to
changes in the biochemical composition of the environment. This modeling of
nutrient metabolism and cell cycle at a mesoscopic scale level leads to a
continuous flow of information between the two disparate spatiotemporal scales
of molecular and cellular dynamics that can be simulated with modern computers
and tested experimentally.Comment: 58 pages, 7 figures, 3 tables, pdf onl
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