1,887 research outputs found
Transmission of Schistosoma haematobium in seasonal pools in the Gambia, with particular reference to the role of human contact
The transmission of S. haematobium in seasonal pools in The Gambia
was investigated during the 1982 and 1983 transmission seasons. Studies
were carried out on (a) infections in the snail intermediate host,
Bulinus senegalensis, (b) cercarial densities in the pools, (c) water
contact behaviour at the pools, and (d) the pattern of human infection.
It was found that seasonal changes in the pools influenced both the
snail populatons and the water contact patterns. Snail infection rates
were low overall but were high in particular months and pools. Most
infections occurred in one pool (maximum monthly mean infection rate
5.9%). Field and laboratory studies indicated that high mortality of
B. senegalensis was counteracted by a high intrinsic rate of natural
increase, and transmission of S. haematobium was maintained by a short
prepatent period of the parasite.
The cercariometric technique used had a 74% recovery accuracy in the
laboratory. Cercarial densities in the pools were generally below 1
cercaria/litre, and the maximum density was 5.8 c/1. Cercarial densities
were highest around midday, close to the vegetation in the middle of the
pool as the pools were drying out. Transmission potential, as measured
by cercarial density, varied between contact sites, months, times of day
and position within a site.
Human water contact was monitored by direct observation using a new
"time-point" method and by recording frequency and duration of water
contact of individuals. The observed activities were mainly for domestic
and recreational purposes. Water contact was focal and seasonal, and the
exposure potential (product of cercarial density and duration of contact
at each pool) was highest at two pools and in the latter half of the
season. The amount of water contact varied markedly between sexes and
age groups. Contact increased progressively between ages 2-9 years,
remaining at very high levels in females over the age of 10 years but
declining to low levels in adult males. Substantial variation occurred
in the contact of individuals in a narrow age group.
An index of individual exposure to infection was calculated for two
cohorts, aged 8-13 years and 2-70 years, by modifying the duration of
contact by each individual by factors for the cercarial density at the
pool used and for the activity performed. The resultant pattern of
exposure to infection was markedly different from the pattern of duration
of water contact: in particular, the mean exposure of adult women was
reduced to less than that of children, although individual adult women
had higher exposure levels than some children.
The intensity of S. haematobium infection was highest in children
aged 5-14 years and declined to low levels in adults. In 2-14 year olds
increased exposure to infection was associated with an increase in
reinfection after treatment. Adults had low levels of both infection and
reinfection, although some had high levels of exposure to infection. It
is concluded that both exposure and age influenced the pattern of
infection in the community.
The combined results of these studies indicates the complexity of
transmission of schistosomiasis from snail to man, and shows that contact
to very low cercarial densities can result in high levels of human
infection
Single-parameter non-adiabatic quantized charge pumping
Controlled charge pumping in an AlGaAs/GaAs gated nanowire by
single-parameter modulation is studied experimentally and theoretically.
Transfer of integral multiples of the elementary charge per modulation cycle is
clearly demonstrated. A simple theoretical model shows that such a quantized
current can be generated via loading and unloading of a dynamic quasi-bound
state. It demonstrates that non-adiabatic blockade of unwanted tunnel events
can obliterate the requirement of having at least two phase-shifted periodic
signals to realize quantized pumping. The simple configuration without multiple
pumping signals might find wide application in metrological experiments and
quantum electronics.Comment: 4 pages, 4 figure
Inverse Compton Scattering as the Source of Diffuse EUV Emission in the Coma Cluster of Galaxies
We have examined the hypothesis that the majority of the diffuse EUV flux in
the Coma cluster is due to inverse Compton scattering of low energy cosmic ray
electrons (0.16 < epsilon < 0.31 GeV) against the 3K black-body background. We
present data on the two-dimensional spatial distribution of the EUV flux and
show that these data provide strong support for a non-thermal origin for the
EUV flux. However, we show that this emission cannot be produced by an
extrapolation to lower energies of the observed synchrotron radio emitting
electrons and an additional component of low energy cosmic ray electrons is
required.Comment: 11 pages, 5 figure
Partitioning of on-demand electron pairs
We demonstrate the high fidelity splitting of electron pairs emitted on
demand from a dynamic quantum dot by an electronic beam splitter. The fidelity
of pair splitting is inferred from the coincidence of arrival in two detector
paths probed by a measurement of the partitioning noise. The emission
characteristic of the on-demand electron source is tunable from electrons being
partitioned equally and independently to electron pairs being split with a
fidelity of 90%. For low beam splitter transmittance we further find evidence
of pair bunching violating statistical expectations for independent fermions
Simultaneous X-ray spectroscopy of YY Gem with Chandra and XMM-Newton
We report on a detailed study of the X-ray spectrum of the nearby eclipsing
spectroscopic binary YY Gem. Observations were obtained simultaneously with
both large X-ray observatories, XMM-Newton and Chandra. We compare the
high-resolution spectra acquired with the Reflection Grating Spectrometer
onboard XMM-Newton and with the Low Energy Transmission Grating Spectrometer
onboard Chandra, and evidence in direct comparison the good performance of both
instruments in terms of wavelength and flux calibration. The strongest lines in
the X-ray spectrum of YY Gem are from oxygen. Oxygen line ratios indicate the
presence of a low-temperature component (1-4 MK) with density n_e < 2 10^{10}
cm^-3. The X-ray lightcurve reveals two flares and a dip corresponding to the
secondary eclipse. An increase of the density during phases of high activity is
suggested from time-resolved spectroscopy. Time-resolved global fitting of the
European Photon Imaging Camera CCD spectrum traces the evolution of temperature
and emission measure during the flares. These medium-resolution spectra show
that temperatures > 10^7 K are relevant in the corona of YY Gem although not as
dominant as the lower temperatures represented by the strongest lines in the
high-resolution spectrum. Magnetic loops with length on the order of 10^9 cm,
i.e., about 5 % of the radius of each star, are inferred from a comparison with
a one-dimensional hydrodynamic model. This suggests that the flares did not
erupt in the (presumably more extended) inter-binary magnetosphere but are
related to one of the components of the binary.Comment: 15 pages, accepted for publication in A&
Cosmology at the Millennium
One hundred years ago we did not know how stars generate energy, the age of
the Universe was thought to be only millions of years, and our Milky Way galaxy
was the only galaxy known. Today, we know that we live in an evolving and
expanding Universe comprising billions of galaxies, all held together by dark
matter. With the hot big-bang model, we can trace the evolution of the Universe
from the hot soup of quarks and leptons that existed a fraction of a second
after the beginning to the formation of galaxies a few billion years later, and
finally to the Universe we see today 13 billion years after the big bang, with
its clusters of galaxies, superclusters, voids, and great walls. The attractive
force of gravity acting on tiny primeval inhomogeneities in the distribution of
matter gave rise to all the structure seen today. A paradigm based upon deep
connections between cosmology and elementary particle physics -- inflation +
cold dark matter -- holds the promise of extending our understanding to an even
more fundamental level and much earlier times, as well as shedding light on the
unification of the forces and particles of nature. As we enter the 21st
century, a flood of observations is testing this paradigm.Comment: 44 pages LaTeX with 14 eps figures. To be published in the Centennial
Volume of Reviews of Modern Physic
Two refreshing views of Fluctuation Theorems through Kinematics Elements and Exponential Martingale
In the context of Markov evolution, we present two original approaches to
obtain Generalized Fluctuation-Dissipation Theorems (GFDT), by using the
language of stochastic derivatives and by using a family of exponential
martingales functionals. We show that GFDT are perturbative versions of
relations verified by these exponential martingales. Along the way, we prove
GFDT and Fluctuation Relations (FR) for general Markov processes, beyond the
usual proof for diffusion and pure jump processes. Finally, we relate the FR to
a family of backward and forward exponential martingales.Comment: 41 pages, 7 figures; version2: 45 pages, 7 figures, minor revisions,
new results in Section
Understanding Galaxy Formation and Evolution
The old dream of integrating into one the study of micro and macrocosmos is
now a reality. Cosmology, astrophysics, and particle physics intersect in a
scenario (but still not a theory) of cosmic structure formation and evolution
called Lambda Cold Dark Matter (LCDM) model. This scenario emerged mainly to
explain the origin of galaxies. In these lecture notes, I first present a
review of the main galaxy properties, highlighting the questions that any
theory of galaxy formation should explain. Then, the cosmological framework and
the main aspects of primordial perturbation generation and evolution are
pedagogically detached. Next, I focus on the ``dark side'' of galaxy formation,
presenting a review on LCDM halo assembling and properties, and on the main
candidates for non-baryonic dark matter. It is shown how the nature of
elemental particles can influence on the features of galaxies and their
systems. Finally, the complex processes of baryon dissipation inside the
non-linearly evolving CDM halos, formation of disks and spheroids, and
transformation of gas into stars are briefly described, remarking on the
possibility of a few driving factors and parameters able to explain the main
body of galaxy properties. A summary and a discussion of some of the issues and
open problems of the LCDM paradigm are given in the final part of these notes.Comment: 50 pages, 10 low-resolution figures (for normal-resolution, DOWNLOAD
THE PAPER (PDF, 1.9 Mb) FROM http://www.astroscu.unam.mx/~avila/avila.pdf).
Lectures given at the IV Mexican School of Astrophysics, July 18-25, 2005
(submitted to the Editors on March 15, 2006
Recommended from our members
International Research Institute for Climate and Society
Contemporary ecological research supports focus on the preservation of habitats and the preservation of keystone species that are critical to the ecological character of the habitats. Conservation of endangered species works best with attention not only to the species but also to the needs of the people who may be adjacent to or bordering habitats.
Southern Sri Lanka fall into the category of globally important biodiversity hotspots. The biggest land animal, the elephant is the keystone species in Sri Lanka outside the highlands. The population of elephants in Sri Lanka is estimated to be between 3000 and 4,000; yet there has been an alarming loss of 1000 elephants during from 1990-2003. Given its island setting and rich hydro-climatic data, Sri Lanka provides a unique opportunity to study the dynamics leading to species loss.
Our work in this project was initially motivated by the practical concerns of our project partners in the Mahaweli River Basin in Sri Lanka where the human-elephant conflict was a major problem. The question that arose was: “Are the climate, water availability and river basin management practices contributing to conflict between elephants and people?” If this was indeed the case, then, could one adaptively manage the river basin, organize agricultural practices, and prioritize conflict mitigation options such as separate habitat enrichment programs? Moreover, could we propose various adaptive measures in changes if one could monitor the climate and environmental conditions and take advantage of seasonal climate predictions
An All-Sky Search for Three Flavors of Neutrinos from Gamma-Ray Bursts with the IceCube Neutrino Observatory
We present the results and methodology of a search for neutrinos produced in
the decay of charged pions created in interactions between protons and
gamma-rays during the prompt emission of 807 gamma-ray bursts (GRBs) over the
entire sky. This three-year search is the first in IceCube for shower-like
Cherenkov light patterns from electron, muon, and tau neutrinos correlated with
GRBs. We detect five low-significance events correlated with five GRBs. These
events are consistent with the background expectation from atmospheric muons
and neutrinos. The results of this search in combination with those of
IceCube's four years of searches for track-like Cherenkov light patterns from
muon neutrinos correlated with Northern-Hemisphere GRBs produce limits that
tightly constrain current models of neutrino and ultra high energy cosmic ray
production in GRB fireballs.Comment: 33 pages, 14 figures; minor changes made to match published version
in the Astrophysical Journal, 2016 June 2
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