Cardiovascular effects of variations in habitual levels of physical activity

Mechanisms involved in human cardiovascular adaption to stress, particularly adaption to different levels of physical activity are determined along with quantitative noninvasive methods for evaluation of cardiovascular function during stess in normal subjects and in individuals with latent or manifest cardiovascular disease. Results are summarized

ArCo: the Italian Cultural Heritage Knowledge Graph

ArCo is the Italian Cultural Heritage knowledge graph, consisting of a network of seven vocabularies and 169 million triples about 820 thousand cultural entities. It is distributed jointly with a SPARQL endpoint, a software for converting catalogue records to RDF, and a rich suite of documentation material (testing, evaluation, how-to, examples, etc.). ArCo is based on the official General Catalogue of the Italian Ministry of Cultural Heritage and Activities (MiBAC) - and its associated encoding regulations - which collects and validates the catalogue records of (ideally) all Italian Cultural Heritage properties (excluding libraries and archives), contributed by CH administrators from all over Italy. We present its structure, design methods and tools, its growing community, and delineate its importance, quality, and impact

Relativity and the lead-acid battery

The energies of the solid reactants in the lead-acid battery are calculated ab initio using two different basis sets at non-relativistic, scalar relativistic, and fully relativistic levels, and using several exchange-correlation potentials. The average calculated standard voltage is 2.13 V, compared with the experimental value of 2.11 V. All calculations agree in that 1.7-1.8 V of this standard voltage arise from relativistic effects, mainly from PbO2 but also from PbSO4

Radiation to supraclavicular and internal mammary lymph nodes in breast cancer increases the risk of stroke

The aim of this study was to assess whether adjuvant treatment of breast cancer (BC) affects the risk of stroke, and to explore radiation targets and fraction doses regarding risk and location of stroke. In a Swedish BC cohort diagnosed during 1970–2003, we carried out a nested case–control study of stroke after BC, with relevant details extracted from medical records. The odds ratio (OR) for radiotherapy (RT) vs that of no RT did not differ between cases and controls (OR=0.85; confidence interval, CI=0.6–1.3). Radiotherapy to internal mammary chain (IMC) and supraclavicular (SCL) lymph nodes vs that of no RT was associated with a higher, although not statistically significant, risk of stroke (OR=1.3; CI=0.8–2.2). In a pooled analysis, RT to IMC and SCL vs the pooled group of no RT and RT to breast/chest wall/axilla (but not IMC and SCL), showed a significant increase of stroke (OR=1.8; CI=1.1–2.8). There were no associations between cancer laterality, targets of RT, and location of stroke. The radiation targets, IMC and SCL, showed a statistically significant trend for an increased risk of stroke with daily fraction dose. Our finding of a target-specific increased risk of stroke and a dose-response relationship for daily fraction dose, indicate that there may be a causal link between RT to the IMC and SCL and risk of stroke

Final State Interaction in Exclusive (e,e′NN)(e,e'NN) Reactions

Contributions of nucleon-nucleon (NN) correlations, meson exchange currents and the residual final state interactions (FSI) on exclusive two-nucleon knock-out reactions induced by electron scattering are investigated. All contributions are derived from the same realistic meson exchange model for the NN interaction. Effects of correlations and FSI are determined in a consistent way by solving the NN scattering equation, the Bethe-Goldstone equation, for two nucleons in nuclear matter. One finds that the FSI re-scattering terms are non-negligible even if the two nucleons are emitted back to back.Comment: 8 pages, 5 figure

New limits on di-nucleons decay into invisible channels

Data of the radiochemical experiment [E.L.Fireman, 1978] with 1.7 t of KC_2H_3O_2, accumulated deep underground during ~1 yr, were reanalyzed to set limits on di-nucleons (nn and np) decays into invisible channels (disappearance, decay into neutrinos, etc.). The obtained lifetime bounds tau_np > 2.1 10^25 yr and tau_nn > 4.2 10^25 yr (at 90% C.L.) are better (or competitive) than those established in the recent experiments.Comment: 3 pages, accepted in JETP Letter

Quasifree pion photoproduction on the deuteron in the Δ\Delta region

Photo production of pions on the deuteron is studied in the spectator nucleon model. The Born terms of the elementary production amplitude are determined in pseudovector $\pi$N coupling and supplied with a form factor. The $\Delta$ resonance is considered both in the $s$ and the $u$ channel. The parameters of the $\Delta$ resonance and the cutoff of the form factors are fixed on the leading photoproduction multipoles. Results for total and differential cross sections are compared with experimental data. Particular attention is paid to the role of Pauli correlations of the final state nucleons in the quasifree case. The results are compared with those for pion photoproduction on the nucleon.Comment: 17 pages LateX2e including 5 postscript figure

Risk of coronary stenosis after adjuvant radiotherapy for breast cancer

Purpose Adjuvant radiotherapy (RT) for breast cancer is associated with an increased risk of ischemic heart disease. We examined the risk of coronary artery stenosis in a large cohort of women with breast cancer receiving adjuvant RT. Methods A cohort of women diagnosed with breast cancer between 1992 and 2012 in three Swedish health care regions (n = 57,066) were linked to the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) to identify women receiving RT who subsequently underwent a percutaneous coronary intervention (PCI) due to coronary stenosis. Cox regression analyses were performed to examine risk of a coronary intervention and competing risk analyses were performed to calculate cumulative incidence. Results A total of 649 women with left-sided breast cancer and 494 women with right-sided breast cancer underwent a PCI. Women who received left-sided RT had a significantly higher risk of a PCI in the left anterior descending artery (LAD) compared to women who received right-sided RT, hazard ratio (HR) 1.44 (95% confidence interval [CI] 1.21-1.77, p < 0.001). For the proximal, mid, and distal LAD, the HRs were 1.60 (95% CI 1.22-2.10), 1.38 (95% CI 1.07-1.78), and 2.43 (95% CI 1.33-4.41), respectively. The cumulative incidence of coronary events at 25 years from breast cancer diagnosis were 7.0% in women receiving left-sided RT and 4.4% in women receiving right-sided RT. Conclusion Implementing and further developing techniques that lower cardiac doses is important in order to reduce the risk of long-term side effects of adjuvant RT for breast cancer.Peer reviewe

Ground-state correlations and final state interactions in the process 3He(e,e'pp)n

The two-proton emission process $^3He(e,e'pp)n$ is theoretically investigated using realistic three-nucleon wave functions and taking the final state interaction into account by an approach which can be used when the value of the three-nucleon invariant mass is either below or above the pion emission threshold. Various kinematical conditions which enhance or minimize the effects of the final state interaction are thoroughly analyzed.Comment: 26 pages, 12 eps-figures. Introduction and abstract updated, few references added and Apendix A remove