Global analysis of electroweak data in the Standard Model

We perform a global fit of electroweak data within the Standard Model, using state-of-the art experimental and theoretical results, including a determination of the electromagnetic coupling at the electroweak scale based on recent lattice calculations. In addition to the posteriors for all parameters and observables obtained from the global fit, we present indirect determinations for all parameters and predictions for all observables. Furthermore, we present full predictions, obtained using only the experimental information on Standard Model parameters, and a fully indirect determination of Standard Model parameters using only experimental information on electroweak data. Finally, we discuss in detail the compatibility of experimental data with the Standard Model and find a global p-value of 0.5

New physics at the FCC-ee: indirect discovery potential

This work has been supported in part by the FEDER/Junta de Andalucia Project Grant P18-FRJ-3735 and by the UK Science and Technology Facilities Council (STFC) Grant ST/P001246/1. Funding for open access charge: Universidad de Granada/CBUA.We review the projected sensitivity to physics beyond the Standard Model via indirect searches at the Future e + e- Circular Collider (FCC-ee). The indirect sensitivity to new physics is discussed both from a model-independent perspective, using the formalism of Effective Field Theories, but also from the point of view of more specific classes of well-motivated models.FEDER/Junta de Andalucia Project P18-FRJ-3735UK Research & Innovation (UKRI) Science & Technology Facilities Council (STFC) ST/P001246/

Higgs boson precision measurements at a 125 GeV muon collider

The s-channel resonant production of the Higgs boson at a 125 GeV muon collider enables a unique way to determine the Higgs properties. However, a clear picture of the achievable Higgs precision has not yet been established. We perform a phenomenological study of the Higgs measurements at such a resonant muon collider Higgs factory and present a systematic, detailed, and consistent extraction of Higgs precision measurements. Many new aspects about the line shape scan, including the scaling with luminosity, optimal scan range, minimal scan steps, correlations with exclusive measurement, effective cross section modeling, etc., are quantitatively studied in this work. All major exclusive Higgs channels are simulated and analyzed with Standard Model background, detection efficiencies, acceptance, angular distributions, and cross -channel correlations. Global analyses of the Higgs couplings are performed in the kappa framework and the effective-field-theory one. The results suggest that the 125 GeV muon-collider Higgs factory provides significant improvement to the Higgs coupling reach of the High-Luminosity LHC and provides independent and distinct Higgs precision information concerning future e+e- colliders. We report results for both 5 and 20 fb-1 integrated luminosity. These results provide comprehensive and quantitative physics understandings helpful in planning for the muon collider road map and global high-energy physics programs.FEDER/Junta de Andalucia project P18-FRJ-3735National Natural Science Foundation of China (NSFC) 12035008United States Department of Energy (DOE) DE-SC0022345National Science Foundation (NSF) PHY-160761

Impact of the Recent Measurements of the Top-Quark and W-Boson Masses on Electroweak Precision Fits

We assess the impact of the very recent measurement of the top-quark mass by the CMS Collaboration on the fit of electroweak data in the standard model and beyond, with particular emphasis on the prediction for the mass of the W boson. We then compare this prediction with the average of the corresponding experimental measurements including the new measurement by the CDF Collaboration, and discuss its compatibility in the standard model, in new physics models with oblique corrections, and in the dimensionsix standard model effective field theory. Finally, we present the updated global fit to electroweak precision data in these models.Ministry of Education, Universities and Research (MIUR)FEDER/Junta de Andalucia projectUnited States Department of Energy (DOE) PRIN 20172LNEEZ P18-FRJ-3735 DE-SC001010

Towards a muon collider

This work was triggered by the Snowmass 2021 Community Planning Exercise [351]. It is based on – and in some cases significantly extends – the Snowmass white papers [352 –357] that have been prepared under the coordination of the IMCC. This work was supported by the EU HORIZON Research and Innovation Actions under the grant agreement number 101094300. Funded by the European Union (EU). Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the EU or European Research Executive Agency (REA). Neither the EU nor the REA can be held responsible for them. The work has been supported by the Fermi Research Alliance, LLC under Contract No. DE-AC02-07CH11359 with the U.S. Department of Energy, Office of Science, Office of High Energy Physics. This work is supported by the Atracción de Talento Grant n. 2022-T1/TIC-24176 of the Comunidad Autónoma de Madrid, Spain. G. Stark is supported by the Department of Energy Office of Science grant DE-SC0010107. The work of R. Dermisek was supported in part by the U.S. Department of Energy under Award No. DE-SC0010120. This work is supported by the Deutsche Forschungsgemeinschaft under Germany’s Excellence Strategy EXC 2121 “Quantum Universe” – 390833306, as well as by the grant 491245950. Contributions from T. Holmes and her group are supported by U.S. Department of Energy, Office of Science, Office of Basic Energy Sciences Energy Frontier Research Centers program under Award Number DE-SC0023122. This manuscript has been authored by employees of Brookhaven Science Associates, LLC under Contract No. DE-SC0012704 with the U.S. Department of Energy. J. Zurita is supported by the Generalitat Valenciana (Spain) through the plan GenT program (CIDEGENT/2019/068), by the Spanish Government (Agencia Estatal de Investigación) and ERDF funds from European Commission (MCIN/AEI/10.13039/501100011033, Grant No. PID2020-114473GB-I00). M. Gallinaro and G. Da Molin acknowledge the support from the Fundação para a Ciência e a Tecnologia (FCT), Portugal. J. Reuter acknowledges the support by the Deutsche Forschungsgemeinschaft (DFG, German Research Association) under Germany’s Excellence Strategy-EXC 2121 “Quantum Universe”-3908333. The work of L. Reina has been supported by the U.S. Department of Energy under grant DE-SC0010102. This work was supported by the EU Horizon 2020 Research and Innovation Programmes: AIDAinnova under Grant Agreement No 101004761, I.FAST under Grant Agreement No 101004730, and the Marie Sklodowska-Curie grant agreement number 101006726. The work of N. Kumar is supported by Department of Science and Technology, Government of India under the SRG grant, Grant Agreement Number SRG/2022/000363. We acknowledge financial support for this research from the United Kingdom Science and Technology Facilities Council via the John Adams Institute, University of Oxford. R. Ruiz acknowledges the support of Narodowe Centrum Nauki under Grant No. 2019/34/E /ST2/00186. R.Ruiz also acknowledges the support of the Polska Akademia Nauk (grant agreement PAN.BFD.S.BDN. 613. 022. 2021 – PASIFIC 1, POPSICLE). S. Trifinopoulos is supported by the Swiss National Science Foundation – project n. P500PT 203156 and by the Center of Theoretical Physics at MIT (MIT-CTP/5538). W. Su is supported by the Junior Foundation of Sun Yat-sen University and Shenzhen Science and Technology Program (Grant No. 202206193000001, 20220816094256002). W. Kilian was supported by the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) under grant 396021762 – TRR 257. The work of Y. Kahn was supported in part by U.S. Department of Energy grant DE-SC0015655. The work of G. Chachamis was supported by the Fundação para a Ciência e a Tecnologia (Portugal) under project CERN/FIS-PAR/0024/2019 and contract ‘Investigador FCT – Individual Call/03216/2017’. The work of J. de Blas has been supported by the FEDER/Junta de Andalucía project grant P18-FRJ-3735. This work is Supported in part by the NSF under Grant No. PHY-2210361 and by the Maryland Center for Fundamental Physics (MCFP). The research activities of K. R. Dienes are supported in part by the U.S. Department of Energy under Grant DE-FG02-13ER41976 DE-SC0009913, and also by the U.S. National Science Foundation through its employee IR/D program. The research activities of B. Thomas are supported in part by the U.S. National Science Foundation under Grant PHY-2014104.A muon collider would enable the big jump ahead in energy reach that is needed for a fruitful exploration of fundamental interactions. The challenges of producing muon collisions at high luminosity and 10 TeV centre of mass energy are being investigated by the recently-formed International Muon Collider Collaboration. This Review summarises the status and the recent advances on muon colliders design, physics and detector studies. The aim is to provide a global perspective of the field and to outline directions for future work.AIDAinnova 101004730, 101004761Atracción de Talento 2022-T1/TIC-24176HORIZON Research and Innovation Actions 101094300H2020 Marie Skłodowska-Curie Actions 101006726 MSCAFEDERGeneralitat Valenciana CIDEGENT/2019/068 GVAHorizon 2020European Regional Development Fund ERDFJunta de Andalucía P18-FRJ-3735Agencia Estatal de Investigación AE

New neutrino interactions at large colliders

35th International Conference of High Energy Physics - ICHEP2010, July 22-28, 2010, Paris (France). PoS(ICHEP 2010) 296.We update present bounds on the helicity of the neutrinos produced in muon decay, including e+e− ! f f LEP 2 data. These significantly reduce the limits derived from all the other electroweak precision data. In Standard Model extensions designed to maximize the RH neutrino production in such a decay the neutrino deficit eventually observable in a near detector at a neutrino factory can be of the order of 5 %. Motivated by the current LHC run at 7 TeV, we also update previous work providing discovery limits on see-saw mediators at this centre of mass energy. Lepton triplets with 200 GeV could be discovered with luminosities of 1 - 1.5 fb−1. Scalar triplets of the same mass might be seen with 0.75 - 3 fb−1. What makes their search also attractive in the first LHC analyses.This work has been partially supported by MICINN (FPA2006-05294), Junta de Andalucía (FQM 101, FQM 03048) and the European Union (MRTN-CT-2006-035505)

Trilepton signals: the golden channel for seesaw searches at LHC

Contribution to the Proceedings of the XXXIII International School of Theoretical Physics "Matter To The Deepest", Ustron, Poland, September 11-16, 2009.The comparison of samples with different number of charged leptons shows that trilepton signals are the most significant ones for seesaw mediators. As previously pointed out, this is indeed the case for scalar (type II) and fermion (type III) triplets at LHC, which can be discovered in this channel for masses up to 500-700 GeV and an integrated luminosity of 30 fb^-1; whereas fermion singlets (type I) are marginally observable if there are no further new physics near the TeV scale. However, if there are new gauge interactions at this scale coupling to right-handed neutrinos, as in left-right models, heavy neutrinos are observable up to masses ~ 2 TeV for new gauge boson masses up to ~ 4 TeV, as we discuss in some detail

Looking for signals beyond the neutrino standard model

Presented at the XXXI International Conference of Theoretical Physics, “Matter to the Deepest”, Ustroń, Poland, September 5–11, 2007.Any new neutrino physics at the TeV scale must include a suppression mechanism to keep its contribution to light neutrino masses small enough. We review some seesaw model examples with weakly broken lepton number, and comment on the expected effects at large colliders and in neutrino oscillations.This work has been supported by MEC project FPA2006-05294, Junta de Andalucía projects FQM 101 and FQM 437, and by the European Community’s Marie-Curie Research Training Network under contract MRTN-CT-2006-035505 “Tools and Precision Calculations for Physics Discoveries at Colliders”. J.A.A.-S. acknowledges support by a MEC Ramón y Cajal contract. J.B. also thanks MEC for an FPU grant

Characterization of multinucleated giant cells in synovium and subchondral bone in knee osteoarthritis and rheumatoid arthritis

Background: Multinucleated giant cells have been noticed in diverse arthritic conditions since their first description in rheumatoid synovium. However, their role in the pathogenesis of osteoarthritis (OA) or rheumatoid arthritis (RA) still remains broadly unknown. We aimed to study the presence and characteristics of multinucleated giant cells (MGC) both in synovium and in subchondral bone tissues of patients with OA or RA. Methods: Knee synovial and subchondral bone samples were from age-matched patients undergoing total joint replacement for OA or RA, or non-arthritic post mortem (PM) controls. OA synovium was stratified by histological inflammation grade using index tissue sections. Synovitis was assessed by Krenn score. Histological studies employed specific antibodies against macrophage markers or cathepsin K, or TRAP enzymatic assay. Results: Inflamed OA and RA synovia displayed more multinucleated giant cells than did non-inflamed OA and PM synovia. There was a significant association between MGC numbers and synovitis severity. A TRAP negative/cathepsin K negative Langhans-like subtype was predominant in OA, whereas both Langhans-like and TRAP-positive/ cathepsin K negative foreign-body-like subtypes were most commonly detected in RA. Plasma-like and foam-like subtypes also were observed in OA and RA synovia, and the latter was found surrounding adipocytes. TRAP positive/ cathepsin K positive osteoclasts were only identified adjacent to subchondral bone surfaces. TRAP positive osteoclasts were significantly increased in subchondral bone in OA and RA compared to PM controls. Conclusions: Multinucleated giant cells are associated with synovitis severity, and subchondral osteoclast numbers are increased in OA, as well as in RA. Further research targeting multinucleated giant cells is warranted to elucidate their contributions to the symptoms and joint damage associated with arthritis

Unbiased constraints on ultralight axion mass from dwarf spheroidal galaxies

It has been suggested that the internal dynamics of dwarf spheroidal galaxies (dSphs) can be used to test whether or not ultralight axions with $m_a\sim 10^{-22}\text{eV}$ are a preferred dark matter candidate. However, comparisons to theoretical predictions tend to be inconclusive for the simple reason that while most cosmological models consider only dark matter, one observes only baryons. Here we use realistic kinematic mock data catalogs of Milky Way dSph's to show that the "mass-anisotropy degeneracy" in the Jeans equations leads to biased bounds on the axion mass in galaxies with unknown dark matter halo profiles. In galaxies with multiple chemodynamical components this bias can be partly removed by modelling the mass enclosed within each subpopulation. However, analysis of the mock data reveals that the least-biased constraints on the axion mass result from fitting the luminosity-averaged velocity dispersion of the individual chemodynamical components directly. Applying our analysis to two dSph's with reported stellar subcomponents, Fornax and Sculptor, and assuming that the halo profile has not been acted on by baryons, yields core radii $r_{c}>1.5$ kpc and $r_c> 1.2$ kpc respectively, and $m_a<0.4\times 10^{-22}\text{eV}$ at 97.5\% confidence. These bounds are in tension with the number of observed satellites derived from simple (but conservative) estimates of the subhalo mass function in Milky Way-like galaxies. We discuss how baryonic feedback might affect our results, and the impact of such a small axion mass on the growth of structures in the Universe.Comment: 17 pages, 12 figures. Version to match MNRAS. Analysis extended to anisotropic mocks. Main conclusions unchange