National Notifiable Diseases Surveillance System Modernization Initiative

NMI Notes will provide monthly news updates about the National Notifiable Diseases Surveillance System (NNDSS) Modernization Initiative (NMI). It is a collaboration by the Centers for Disease Control and Prevention (CDC), Council of State and Territorial Epidemiologists (CSTE), and Association of Public Health Laboratories (APHL)

Acid Catalyzed Polymerization of Phenyl Ethane 1,2-diol for One-Pot Synthesis of Organosoluble Poly(phenylene Vinylene)

Acid catalyzed polymerization of phenyl ethane 1,2-diol is realized for the first time via a novel one-pot coupling reaction to produce organosoluble poly(phenylene vinylene). A variety of experimental conditions were investigated. PPV structure was confirmed by 13C-NMR and 1H-NMR chemical shifts. Fluorescence spectra of the polymer showed emission in the visible range, as to be expected. Average PPV molecular weights ranged from 670 to 6200 Da. The methanesulfonic acid (MesOH) catalyzed syntheses were shown to produce higher molecular weight and purity PPV than the sulfuric acid (H2SO4) counterparts, although both are able to produce organosoluble products. </div

Poly(o-aminophenol) prepared by Cu(II) catalyzed air oxidation and its use as a bio-sensing architecture

A novel procedure for the preparation of organosoluble polyo-aminophenol) is described. The method pertains to the reduction of CuBr2 with o-amino phenol OAP) at room temperature. The air oxidation of the CuI) species to Cu(II) facilitated the formation of polyo-aminophenol) POAP) in repeated cycles. The obtained polymer, soluble in common organic solvents such as dimethylformamide, acetone, and chloroform, was characterized by spectral analyses. It was found that both quinoid and benzoid structures were present in the polymer chain. Polyo-aminophenol) architecture was then applied as an immobilization matrix to obtain a long-lived and fast response bio-sensing system. Glucose oxidase GOx) was utilized as a model enzyme for the detection of glucose in beverages. After the optimization studies, the surface characterization of POAP/GOx was performed by scanning electron microscopy SEM) measurements. Under the optimized conditions, the biosensor exhibited a rapid response 2 s), a low detection limit 0.02 mM), and high sensitivity 79.80 mu A mM(-1) cm(-2)). The K-M(app) value was determined as 0.16 mM. Furthermore, there was no considerable activity loss for 15 days for the POAP/GOx biofilm indicating excellent recovery as tested with real samples