504 research outputs found

    Joint claims for JSA evaluation: synthesis of findings

    Get PDF

    The usefulness of accrual-based surpluses in the Canadian public sector

    Get PDF
    This paper investigates how useful accrual-based surpluses are when predicting future cash flows and surpluses in the context of the Canadian public sector. We provide evidence that surpluses incrementally enhance the ability of operating cash flows to predict future cash flows and surpluses. Analysis of our accrual quality model illustrates that in the public sector, accruals accounting is useful in mitigating the noise in operating cash flows. We also find that decomposing surpluses into operating cash flows and accruals enhances the ability of surpluses to forecast future cash flows and surpluses. Therefore, we conclude that aggregate and disaggregated surpluses are positively related to both relevance and reliability. We also find a lack of test results to support the presence of conservatism in the Canadian public sector, and confirm that the usefulness of surpluses in making predictions is independent of selected control factors

    On the extension of the complex-step derivative technique to pseudospectral algorithms

    Get PDF
    Abstract The complex-step derivative (CSD) technique is a convenient and highly accurate strategy to perform a linearized ''perturbation'' analysis to determine a ''directional derivative'' via a minor modification of an existing nonlinear simulation code. The technique has previously been applied to nonlinear simulation codes (such as finite-element codes) which employ real arithmetic only. The present note examines the suitability of this technique for extension to efficient pseudospectral simulation codes which nominally use the fast Fourier transform (FFT) to convert back and forth between the physical and transformed representations of the system. It is found that, if used carefully, this extension retains the remarkable accuracy of the CSD approach. However, to perform this extension without sacrificing this accuracy, particular care must be exercised; specifically, the state (real) and perturbation (imaginary) components of the complexified system must be transformed separately and arranged in such a manner that they are kept distinct during the process of differentiation in the transformed space in order to avoid the linear combination of the large and small quantities in the analysis. It is shown that this is relatively straightforward to implement even in complicated nonlinear simulation codes, thus positioning the CSD approach as an attractive and relatively simple alternative to hand coding a perturbation (a.k.a. ''tangent linear'') code for determining the directional derivative even when pseudospectral algorithms are employed. Published by Elsevier Science B.V

    Optimization of Drug Delivery by Drug-Eluting Stents

    No full text
    International audienceDrug-eluting stents (DES), which release anti-proliferative drugs into the arterial wall in a controlled manner, have drastically reduced the rate of in-stent restenosis and revolutionized the treatment of atherosclerosis. However, late stent thrombosis remains a safety concern in DES, mainly due to delayed healing of the endothelial wound inflicted during DES implantation. We present a framework to optimize DES design such that restenosis is inhibited without affecting the endothelial healing process. To this end, we have developed a computational model of fluid flow and drug transport in stented arteries and have used this model to establish a metric for quantifying DES performance. The model takes into account the multi-layered structure of the arterial wall and incorporates a reversible binding model to describe drug interaction with the cells of the arterial wall. The model is coupled to a novel optimization algorithm that allows identification of optimal DES designs. We show that optimizing the period of drug release from DES and the initial drug concentration within the coating has a drastic effect on DES performance. Paclitaxel-eluting stents perform optimally by releasing their drug either very rapidly (within a few hours) or very slowly (over periods of several months up to one year) at concentrations considerably lower than current DES. In contrast, sirolimus-eluting stents perform optimally only when drug release is slow. The results offer explanations for recent trends in the development of DES and demonstrate the potential for large improvements in DES design relative to the current state of commercial devices

    Video OWL-ViT: Temporally-consistent open-world localization in video

    Full text link
    We present an architecture and a training recipe that adapts pre-trained open-world image models to localization in videos. Understanding the open visual world (without being constrained by fixed label spaces) is crucial for many real-world vision tasks. Contrastive pre-training on large image-text datasets has recently led to significant improvements for image-level tasks. For more structured tasks involving object localization applying pre-trained models is more challenging. This is particularly true for video tasks, where task-specific data is limited. We show successful transfer of open-world models by building on the OWL-ViT open-vocabulary detection model and adapting it to video by adding a transformer decoder. The decoder propagates object representations recurrently through time by using the output tokens for one frame as the object queries for the next. Our model is end-to-end trainable on video data and enjoys improved temporal consistency compared to tracking-by-detection baselines, while retaining the open-world capabilities of the backbone detector. We evaluate our model on the challenging TAO-OW benchmark and demonstrate that open-world capabilities, learned from large-scale image-text pre-training, can be transferred successfully to open-world localization across diverse videos.Comment: ICCV 202

    Caesarean section for non-medical reasons at term

    Get PDF
    Background: Caesarean section rates are progressively rising in many parts of the world. One suggested reason is increasing requests by women for caesarean section in the absence of clear medical indications, such as placenta praevia, HIV infection, contracted pelvis and, arguably, breech presentation or previous caesarean section. The reported benefits of planned caesarean section include greater safety for the baby, less pelvic floor trauma for the mother, avoidance of labour pain and convenience. The potential disadvantages, from observational studies, include increased risk of major morbidity or mortality for the mother, adverse psychological sequelae, and problems in subsequent pregnancies, including uterine scar rupture and greater risk of stillbirth and neonatal morbidity. An unbiased assessment of advantages and disadvantages would assist discussion of what has become a contentious issue in modern obstetrics. Objectives: To assess, from randomised trials, the effects on perinatal and maternal morbidity and mortality, and on maternal psychological morbidity, of planned caesarean delivery versus planned vaginal birth in women with no clear clinical indication for caesarean section. Search methods: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (April 2009). Selection criteria: All comparisons of intention to perform caesarean section and intention for women to give birth vaginally; random allocation to treatment and control groups; adequate allocation concealment; women at term with single fetuses with cephalic presentations and no clear medical indication for caesarean section. Data collection and analysis: We identified no studies that met the inclusion criteria. Main results: There were no included trials. Authors' conclusions: There is no evidence from randomised controlled trials, upon which to base any practice recommendations regarding planned caesarean section for non-medical reasons at term. In the absence of trial data, there is an urgent need for a systematic review of observational studies and a synthesis of qualitative data to better assess the short- and long-term effects of caesarean section and vaginal birth

    Tethered Balloon-Based Experiment of Surface Water Height Using Satellite Signals of Opportunity

    Get PDF
    Signals of Opportunity (SoOp) is an area of radio science that leverages existing ambient signals from spacecraft, aircraft, and ground-based radio systems to perform radio science without spending time or resources constructing new transmission infrastructure. It has been conceptualized that SmallSats or CubeSats can perform similar SoOp missions by augmenting pre-existing spacecraft missions - specifically radio/radar missions. During the summer of 2019, student-interns at the National Aeronautics and Space Administration's (NASA) Jet Propulsion Laboratory (JPL) under the Innovation to Flight (i2F) program tested the first airborne SoOp demo via a tethered aerostat - a valuable step towards getting a SoOp demo in orbit. The airborne SoOp demo received direct and bounced signals from multiple geosynchronous equatorial orbit (GEO) satellites by using two on-board wide-band grid antennas. One antenna was pointed at the sky at appropriate azimuth and elevation angles to receive a direct GEO signal. The other antenna was pointed at an identical azimuth angle with a mirrored elevation angle so as to receive the same GEO signal reflected from a body of water below. Both antennas were secured on adjustable mounts to allow for pointing changes and permit data collection from multiple satellites. This initial test proves the scientific and technological feasibility of doing further airborne SoOp tests, potentially on aircraft, unmanned aerial vehicles (UAV), high altitude balloons (HAB), and SmallSats or CubeSats
    corecore