Trial and settlement negotiations between asymmetrically skilled parties

Parties engaged in a litigation generally enter the discovery process with different informations regarding their case and/or an unequal endowment in terms of skill and ability to produce evidence and predict the outcome of a trial. Hence, they have to bear different legal costs to assess the (equilibrium) plaintiff's win rate. The paper analyses pretrial negotiations and revisits the selection hypothesis in the case where these legal expenditures are private information. This assumption is consistent with empirical evidence (Osborne, 1999). Two alternative situations are investigated, depending on whether there exists a unilateral or a bilateral informational asymmetry.\ Our general result is that efficient pretrial negotiations select cases with the smallest legal expenditures as those going to trial, while cases with largest costs prefer to settle. Under the one-sided asymmetric information assumption, we find that the American rule yields more trials and higher aggregate legal expenditures than the French and British rules. The two-sided case leads to a higher rate of trials, but in contrast provides less clear-cut predictions regarding the influence of fee-shifting.litigation, unilateral and bilateral asymmetric information, legal expenditures

Lead-induced DNA damage in Vicia faba root cells: Potential involvement of oxidative stress

Genotoxic effects of lead (0–20 µM) were investigated in whole-plant roots of Vicia faba L., grown hydroponically under controlled conditions. Lead-induced DNA damage in V. faba roots was evaluated by use of the comet assay, which allowed the detection of DNA strand-breakage and with the V. faba micronucleus test, which revealed chromosome aberrations. The results clearly indicate that lead induced DNA fragmentation in a dose-dependant manner with a maximum effect at 10 µM. In addition, at this concentration, DNA damage time-dependently increased until 12 h. Then, a decrease in DNA damages was recorded. The significant induction of micronucleus formation also reinforced the genotoxic character of this metal. Direct interaction of lead with DNA was also evaluated with the a-cellular comet assay. The data showed that DNA breakages were not associated with a direct effect of lead on DNA. In order to investigate the relationship between lead genotoxicity and oxidative stress, V. faba were exposed to lead in the presence or absence of the antioxidant Vitamin E, or the NADPH-oxidase inhibitor dephenylene iodonium (DPI). The total inhibition of the genotoxic effects of lead (DNA breakage and micronucleus formation) by these compounds reveals the major role of reactive oxygen species (ROS) in the genotoxicity of lead. These results highlight, for the first time in vivo and in whole-plant roots, the relationship between ROS, DNA strand-breaks and chromosome aberrations induced by lead

Lead Uptake, Toxicity, and Detoxification in Plants

Lead has gained considerable attention as a persistent toxic pollutant of concern, partly because it has been prominent in the debate concerning the growing anthropogenic pressure on the environment. The purpose of this review is to describe how plants take lead up and to link such uptake to the ecotoxicity of lead in plants. Moreover, we address the mechanisms by which plants or plant systems detoxify lead. Lead has many interesting physico-chemical properties that make it a very useful heavy metal. Indeed, lead has been used by people since the dawn of civilization. Industrialization, urbanization, mining, and many other anthropogenic activities have resulted in the redistribution of lead from the earth’s crust to the soil and to the environment. Lead forms various complexes with soil components, and only a small fraction of the lead present as these complexes in the soil solution are phytoavailable. Despite its lack of essential function in plants, lead is absorbed by them mainly through the roots from soil solution and thereby may enter the food chain. The absorption of lead by roots occurs via the apoplastic pathway or via Ca2+-permeable channels. The behavior of lead in soil, and uptake by plants, is controlled by its speciation and by the soil pH, soil particle size, cation-exchange capacity, root surface area, root exudation, and degree of mycorrhizal transpiration. After uptake, lead primarily accumulates in root cells, because of the blockage by Casparian strips within the endodermis. Lead is also trapped by the negative charges that exist on roots’ cell walls. Excessive lead accumulation in plant tissue impairs various morphological, physiological, and biochemical functions in plants, either directly or indirectly, and induces a range of deleterious effects. It causes phytotoxicity by changing cell membrane permeability, by reacting with active groups of different enzymes involved in plant metabolism and by reacting with the phosphate groups of ADP or ATP, and by replacing essential ions. Lead toxicity causes inhibition of ATP production, Lead Uptake, Toxicity, and Detoxification in Plants 131 lipid peroxidation, and DNA damage by over production of ROS. In addition, lead strongly inhibits seed germination, root elongation, seedling development, plant growth, transpiration, chlorophyll production, and water and protein content. The negative effects that lead has on plant vegetative growth mainly result from the following factors: distortion of chloroplast ultrastructure, obstructed electron transport, inhibition of Calvin cycle enzymes, impaired uptake of essential elements, such as Mg and Fe, and induced deficiency of CO2 resulting from stomatal closure. Under lead stress, plants possess several defense strategies to cope with lead toxicity. Such strategies include reduced uptake into the cell; sequestration of lead into vacuoles by the formation of complexes; binding of lead by phytochelatins, glutathione, and amino acids; and synthesis of osmolytes. In addition, activation of various antioxidants to combat increased production of lead-induced ROS constitutes a secondary defense system

Personal Bankruptcy Law, Fresh Starts, and Judicial Practice

We explore the ways French judges respond to the possibility of discharging personal debts in exchange for liquidation of debtors’ assets. We present empirical results on the determinants of judicial selection between debtors whose debts are wiped out and those who have to reimburse them. We find that French judges tend to disqualify debtors with multiple creditors from debt discharge, and are sensitive to regional labor market conditions. These empirical results help us understand better how French personal bankruptcy laws perform compared to other national systems. Finally, our results serve to fill the gap between bankruptcy rules and judicial practice.Personal bankruptcy, over-indebtedness

Lead-induced genotoxicity to Vicia faba L.roots in relation with metal cell uptake and initial speciation

Formation of organometallic complexes in soil solution strongly influence metals phytoavailability. However, only few studies deal with the influence of metalspeciation both on plant uptake and genotoxicity. In the present study, Viciafaba seedlings were exposed for 6 h in controlled hydroponic conditions to 5 μM of lead nitrate alone and chelated to varying degrees by different organic ligands. Ethylenediaminetetraacetic acid and citric acid were, respectively, chosen as models of humic substances and low weight organic acids present in natural soil solutions. Visual Minteq software was used to estimate free lead cations concentration and ultimately to design the experimental layout. For all experimental conditions, both micronucleus test and measure of leaduptake by plants were finally performed. Chelation of Pb by EDTA, a strong chelator, dose-dependently increased the uptake in V. faba roots while its genotoxicity was significantly reduced, suggesting a protective role of EDTA. A weak correlation was observed between total lead concentration absorbed by roots and genotoxicity (r2=0.65). In contrast, a strong relationship (r2=0.93) exists between Pb2+ concentration in exposure media and genotoxicity in the experiment performed with EDTA. Citric acid induced labile organometallic complexes did not demonstrate any significant changes in leadgenotoxicity or uptake. These results demonstrate that metalspeciation knowledge could improve the interpretation of V. fabagenotoxicity test performed to test soil quality

Visual Servoing using the Sum of Conditional Variance

International audienceIn this paper we propose a new way to achieve direct visual servoing. The novelty is the use of the sum of conditional variance to realize the optimization process of a positioning task. This measure, which has previously been used successfully in the case of visual tracking, has been shown to be invariant to non-linear illumination variations and inexpensive to compute. Compared to other direct approaches of visual servoing, it is a good compromise between techniques using the illumination of pixels which are computationally inexpensive but non robust to illumination variations and other approaches using the mutual information which are more complicated to compute but offer more robustness towards the variations of the scene. This method results in a direct visual servoing task easy and fast to compute and robust towards non-linear illumination variations. This paper describes a visual servoing task based on the sum of conditional variance performed using a Levenberg-Marquardt optimization process. The results are then demonstrated through experimental validations and compared to both photometric-based and entropy-based techniques

Dense non-rigid visual tracking with a robust similarity function

International audienceThis paper deals with dense non-rigid visual tracking robust towards global illumination perturbations of the observed scene. The similarity function is based on the sum of condi- tional variance (SCV). With respect to most approaches that minimize the sum of squared differences, which is poorly robust towards illumination variations in the scene, the choice of SCV as our registration function allows the approach to be naturally robust towards global perturbations. Moreover, a thin-plate spline warping function is considered in order to take into account deformations of the observed template. The proposed approach, after being detailed, is tested in nominal conditions and on scenes where light perturbations occur in order to assess the robustness of the approach

Assessment of the genotoxicity of Cu and Zn in raw and anaerobically digested slurry with the Vicia faba micronucleus test

Genotoxicity of Cu and Zn was assessed by use of the micronucleus (MN) test on Vicia faba roots. Plants were exposed to various leachates of rawand anaerobically digested pig slurry, with maximum total concentrations of 200MCu and 600MZn. The results indicated stabilisation of the organic matter during anaerobic digestion of the slurry and bioconversion of some phytotoxic organic compounds (e.g. phenols or p-cresol), but did not showa relationship between Cu and Zn concentrations and MN frequency. Exposure of Vicia plants to binary inorganic solutions of Cu and Zn (CuSO4/ZnSO4, 1:3) showed a significant micronucleus induction at concentrations of 40M Cu and 120M Zn and higher. When MN frequency was plotted against dissolved Cu (<0.45m), applied as slurry or as CuSO4, a single curve was obtained. At concentrations lower than 10M, modulation of the genotoxic effect of Cu was found. At concentrations up to 150M,MNinduction increased significantly, while phytotoxic symptoms appeared at higher concentrations

Imaging and manipulating electrons in a 1D quantum dot with Coulomb blockade microscopy

Motivated by the recent experiments by the Westervelt group using a mobile tip to probe the electronic state of quantum dots formed on a segmented nanowire, we study the shifts in Coulomb blockade peak positions as a function of the spatial variation of the tip potential, which can be termed "Coulomb blockade microscopy". We show that if the tip can be brought sufficiently close to the nanowire, one can distinguish a high density electronic liquid state from a Wigner crystal state by microscopy with a weak tip potential. In the opposite limit of a strongly negative tip potential, the potential depletes the electronic density under it and divides the quantum wire into two partitions. There the tip can push individual electrons from one partition to the other, and the Coulomb blockade micrograph can clearly track such transitions. We show that this phenomenon can be used to qualitatively estimate the relative importance of the electron interaction compared to one particle potential and kinetic energies. Finally, we propose that a weak tip Coulomb blockade micrograph focusing on the transition between electron number N=0 and N=1 states may be used to experimentally map the one-particle potential landscape produced by impurities and inhomogeneities.Comment: 4 pages 7 figure