El leño en el fuego. Hacia una relectura contemporánea del problema del Sobrenatural en clave trinitaria y personalista

El siguiente artículo busca aportar elementos para la relectura del problema del Sobrenatural desde una perspectiva teológica contemporánea en clave trinitaria y personalista. La primera sección se ocupará de una apretada síntesis de los aportes de los teólogos de la década del 40 y 50. El segundo momento intentará esbozar una re-formulación de las conquistas recurriendo las nociones de leyes perijoréticas y el binomio creación - pascua, mientras que el tercer bloque propondrá algunas pistas, explorando las categorías de “divinización como verdadera humanización” y el puente pneumatológico que se establece entre ontología trinitaria y estética teológica

¿Transubstanciados? Esbozos eucarísticos de una antropología en clave sinodal

La sinodalidad puede abordarse desde distintos ámbitos. Estas líneas proponen centrar la mirada en su declinación antropológica, cuyo núcleo se encuentra en el exacto cruce de la escatología y la eclesiología. A partir de la asociación identitaria con la eucaristía, jugaremos con los distintos elementos que constituyen lo que podríamos llamar una antropología sinodal: eucaristía, tensión escatológica, ser para la comunión y el cuerpo de Cristo como ámbito propio de la “subsistencia” propia de la nueva creatura

¿Transubstanciados? Esbozos eucarísticos de una antropología en clave sinodal

Synodality can be approached from different areas. These lines propose to focus on its anthropological decline, whose core is found at the exact intersection of eschatology and ecclesiology. From the identity association with the Eucharist, we will play with the different elements that constitute what we could call a synodal anthropology: Eucharist, eschatological tension, being for communion and the body of Christ as the proper scope of the new creature’s “subsistence”.La sinodalidad puede abordarse desde distintos ámbitos. Estas líneas proponen centrar la mirada en su declinación antropológica, cuyo núcleo se encuentra en el exacto cruce de la escatología y la eclesiología. A partir de la asociación identitaria con la eucaristía, jugaremos con los distintos elementos que constituyen lo que podríamos llamar una antropología sinodal: eucaristía, tensión escatológica, ser para la comunión y el cuerpo de Cristo como ámbito propio de la “subsistencia” propia de la nueva creatura

Logos and poetry as world events and flesh : Edith Stein y Christophe Lebreton

Resumen: El objeto del presente artículo es señalar la convergencia de dos tipos de discurso: el de la racionalidad lógica y el de la poesía, a partir de las obras de Edith Stein y Christophe Lebreton. Ambos, considerados a menudo de manera dialéctica, pertenecen al orden del espíritu humano encarnado en el tiempo y, por lo tanto, no se excluyen recíprocamente, sino que se encuentran en el mismo acontecer de la carne.Abstract: The scope of the present article is to evidence the confluence of two different kind of speech: the rational and the poetic one, moving from the Works of Edith Stein and Christophe Lebreton. Both types of speech, usually presented as opposed, belong to the realm of the human spirit - incarnated in time. Therefore, they do not exclude each other but they meet themselves at the event of flesh

La nupcialidad entre la estética teológica y la ontología trinitaria

This article aims to place Nuptiality in the hermeneutic circularity between Antropology and Trinity, in order to recover its speculative strenght for Theology, Philosophy and contemporaneous Mystic. John of the Cross, Edith Stein and Christophe Lebreton’s testimonies become the source from which this paper intends to establish a fruitful bond between Theological Aesthetics and Trinitarian Ontology, which leads to skecht out eight distinctive notes that characterize Nuptiality with a new light.Este artículo se propone situar la categoría de nupcialidad en la circularidad hermenéutica entre lo antropológico y lo trinitario, a fin de recuperar su poder especulativo y reconfigurador tanto para la teología como para la filosofía y la mística contemporáneas. Para ello se apela a la fuerza de las existencias teologales de Juan de la Cruz, Edith Stein y Christophe Lebreton. A partir de sus testimonios el artículo postula una relación fecunda entre Estética teológica y Ontología trinitaria que redunda en una caracterización actualizada de la nupcialidad compuesta por ocho notas distintivas que el texto desarrolla

The challenge of environmental samples for PCR detection of phytopathogenic bacteria: a case study of citrus huanglongbing disease

Huanglongbing (HLB) is the most devastating citrus disease and is associated with three bacterial species of the genus ‘Candidatus Liberibacter’ transmitted by insect vectors. The early detection of HLB is based on PCR methods, and it is one of the cornerstones for preventing incursion into disease-free countries. However, the detection of phytopathogenic bacteria with PCR-based methods is problematic in surveys that include a variety of samples of different origins. Here, we first report the proportion of amplifications obtained by two standardized real-time PCR methods for the diagnosis of HLB in various environmental samples that include plants, psyllid vectors, and parasitic wasps of the psyllids. The results of 4915 samples showed that 9.3% of them were amplified by the first rapid screening test and only 0.3% by the more specific tests. Most of the amplifications were associated with parasitic wasps. We designed the primers external to the target regions of both real-time PCR protocols to determine if amplifications belonged to one of three ‘Ca. Liberibacter’ species associated with HLB. The bioinformatic analysis of the sequences obtained with these primers revealed that all these amplifications came from the presence of other prokaryotic organisms in the samples. The primers developed in this study overcome the problem of undesired amplification in environmental samples. Thus, they could be used in future survey protocols to prevent the eradication of negative trees and the generation of unjustified alarms

N=1 SQCD-like theories with N_f massive flavors from AdS/CFT and beta functions

We study new supergravity solutions related to large-$N_c$ ${\cal N}=1$ supersymmetric gauge field theories with a large number $N_f$ of massive flavors. We use a recently proposed framework based on configurations with $N_c$ color D5 branes and a distribution of $N_f$ flavor D5 branes, governed by a function $N_f S(r)$. Although the system admits many solutions, under plausible physical assumptions the relevant solution is uniquely determined for each value of $x\equiv N_f/N_c$. In the IR region, the solution smoothly approaches the deformed Maldacena-N\'u\~nez solution. In the UV region it approaches a linear dilaton solution. For $x<2$ the gauge coupling $\beta_g$ function computed holographically is negative definite, in the UV approaching the NSVZ $\beta$ function with anomalous dimension $\gamma_0= -1/2$ (approaching $-3/(32\pi^2)(2N_c-N_f)g^3$)), and with $\beta_g \to-\infty$ in the IR. For $x=2$, $\beta_g$ has a UV fixed point at strong coupling, suggesting the existence of an IR fixed point at a lower value of the coupling. We argue that the solutions with $x>2$ describe a "Seiberg dual" picture where $N_f-2N_c$ flips sign.Comment: 18 pages, 10 figure

Soluble galectin-3 as a microenvironment-relevant immunoregulator with prognostic and predictive value in lung adenocarcinoma

Despite the success of therapies in lung cancer, more studies of new biomarkers for patient selection are urgently needed. The present study aims to analyze the role of galectin-3 (GAL-3) in the lung tumor microenvironment (TME) using tumorspheres as a model and explore its potential role as a predictive and prognostic biomarker in non-small cell lung cancer (NSCLC) patients. For in vitro studies, lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) primary cultures from early-stage patients and commercial cell lines were cultured, using tumorsphere-forming assays and adherent conditions for the control counterparts. We analyzed the pattern of secretion and expression of GAL-3 using reverse transcription-quantitative real-time PCR (RTqPCR), immunoblot, immunofluorescence, flow cytometry and immunoassay analysis. Our results using three-dimensional (3D) models of lung tumor cells revealed that soluble GAL-3 (sGAL-3) is highly expressed and secreted. To more accurately mimic the TME, a co-culture of tumorspheres and fibroblasts was used, revealing that GAL-3 could be important as an immunomodulatory molecule expressed and secreted in the TME, modulating immunosuppression through regulatory T cells (TREGS). In the translational phase, we confirmed that patients with high expression levels of GAL-3 had more TREGS, which suggests that tumors may be recruiting this population through GAL-3. Next, we evaluated levels of sGAL-3 before surgery in LUAD and LUSC patients, hypothesizing that sGAL-3 could be used as an independent prognostic biomarker for overall survival and relapse-free survival in early-stage LUAD patients. Additionally, levels of sGAL-3 at pretreatment and first response assessment from plasma to predict clinical outcomes in advanced LUAD and LUSC patients treated with first-line pembrolizumab were evaluated, further supporting that sGAL-3 has a high efficiency in predicting durable clinical response to pembrolizumab with an area under curve (AUC) of 0.801 (p=0.011). Moreover, high levels might predict decreased progression-free survival and overall survival to anti-PD-1 therapy, with sGAL-3 being a prognosis-independent biomarker for advanced LUAD

Seedling competition between Pennisetum setaceum (Poaceae) and three native weeds of La Primavera wood, Guadalajara, Jalisco (México)

Pennisetum setaceum (Forssk.) Chiov., 1923 is an exotic grass from the Arabian Peninsula that has been very successful as an ornamental plant worldwide in recent years. Unfortunately, it has proved to be a very competitive invader, causing ecological problems in several regions of the world. We don't know exactly how this species interacts with native weeds in Mexico. Our study aims to show the interactions of Pennisetum with three species of native weeds in the surroundings of the metropolitan area of Guadalajara, Jalisco, Mexico: Aeschynomene villosa var. longifolia (Micheli) Rudd, Desmodium aparines (Link) DC. and Paspalum notatum (Flüggé). The seeds of Pennisetum were tested in monospecific groups (competing against itself) and in association with each of the native species mentioned and with a treatment together with all the compound of the species mentioned, thus simulating what could happen in natural conditions upon the arrival of the seeds of P. setaceum in a degraded soil of Guadalajara. The results show how the biomass produced and the speed of growth of Pennisetum can be a real alarm for the conservation of local germplasm