MOOCs sobre tecnologia assistiva no contexto educacional: uma revisão sistemática

Para muitos estudantes com deficiência, o acesso a recursos e serviços de Tecnologia Assistiva (TA) pode ser o diferencial para que tenham autonomia e êxito no contexto educacional. Para viabilizar essa realidade, há demanda crescente por capacitação em TA que chegue até os envolvidos nesse processo, de forma ampla, aberta e gratuita, características estas que podem ser contempladas pela oferta de Massive Open Online Courses (MOOCs). Nesse sentido, foi conduzida uma revisão sistemática para prover uma visão geral do estado corrente da pesquisa relacionada à utilização de MOOCs para oferecer capacitação em TA no contexto educacional. Como resultados, verificouse a quase inexistência de MOOCs sobre TA e que o tema ainda é pouco explorado, mas com grande potencial para atender uma demanda urgente e crescente no contexto educacional

RECURSOS PEDAGÓGICOS PARA O ENSINO DE PROGRAMAÇÃO DE ESTUDANTES COM DEFICIÊNCIA VISUAL: UMA REVISÃO SISTEMÁTICA DA LITERATURA

O ensino de programação é uma atividade complexa que muitas vezes é abordadaem sala de aula utilizando-se de elementos visuais (imagens, vídeos e animações). Porém, o processo de ensino e de aprendizagem fica prejudicado quando um aluno com deficiência visual não consegue acompanhar as atividades realizadas em sala de aula. Desse modo, é essencial utilizar ou propor recursos pedagógicos que viabilizem a inclusão desses estudantes, possibilitando a compreensão dos conceitos apresentados em aula. Este artigo apresenta o percurso e os resultados de uma revisão sistemática da literatura com foco na identificação desse tipo de recurso pedagógico. Os principais resultados encontrados demonstram que os recursos para o ensino de programação relacionam-se às múltiplas possibilidades de percepção, em especial, a auditiva e a tátil

Preferred ph of silver catfish Rhamdia quelen acclimated to different ph levels

The aim of this study was to investigate the preferred pH in silver catfish Rhamdia quelen acclimated to different pH. Fish were acclimated for one week at pH 4.2±0.1, 5.2±0.1, 6.3±0.1, 7.2±0.1, 8.0±0.1, and 9.0±0.1 and after this period, transferred to a polyethylene tube with a pH gradient from 3.5 to 10.0. The position of the fish in the pH gradient was observed 1, 6 and 12 hours after transference. Results indicated that acclimation to different pH did not change pH preference of silver catfish (pH 7.0-7.6), occurring only a transitory variation around 6 hours after transference. This pH preference coincides with the best pH indicated in the literature for growth of this species.O objetivo deste estudo foi verificar o pH preferencial de jundiás Rhamdia quelen aclimatados em diferentes pH. Os jundiás foram aclimatados por uma semana em pH 4,2±0,1; 5,2±0,1; 6,3±0,1; 7,2±0,1; 8,0±0,1 e 9,0±0,1 e, após esse período, transferidos para um tubo de polietileno com pH variando entre 3,5 e 10. A posição dos exemplares no gradiente de pH foi observada 1, 6 e 12 horas após a transferência. Os resultados indicam que a aclimatação em diferentes pH não altera o pH preferencial dos peixes (pH 7.0-7.6), ocorrendo apenas uma variação transitória em torno de 6 horas após a transferência. Este pH preferencial coincide com o pH indicado na literatura como o melhor para o crescimento desta espécie

Versican expression in canine carcinomas in benign mixed tumours: is there an association with clinical pathological factors, invasion and overall survival?

Abstract Background Components of the extracellular matrix have been studied in an attempt to elucidate the mechanisms involved in the biological behaviour of tumours. The presence of the proteoglycan versican has been strongly associated with cancer development and progression. However, relationship between versican expression and clinical pathological factors and overall survival has not been previously studied in veterinary medicine. Carcinomas in benign mixed tumours (CBMTs) are one of the most common malignant tumours in female canines and can serve as models for studies of tumour progression. The aim of this study was to evaluate the expression of versican in in situ and invasive carcinomatous areas of canine CBMTs and to evaluate possible associations of versican expression with other classic prognostic factors and overall survival. Results Clinical staging; histological grade determination; immunohistochemical staining for versican, E-cadherin and Ki-67; and confirmation of invasion areas by staining for p63 and smooth muscle α-actin (α-SMA) were performed on 49 canine cases of CBMT. Tumour invasion was considered when suspicious Haematoxylin-Eosin (HE)-stained areas showed a total loss of α-SMA and p63 immunoreactivity. Versican immunoreactivity was less intense in the areas adjacent to the in situ carcinomatous regions, compared to invasive regions, which showed extensive and strong staining. Conclusions Our data reveal that in canine CBMTs, versican expression differs significantly between invasive and in situ areas, suggesting a role for this molecule in tumour progression. Although a direct relationship exists between versican and invasiveness, our results indicate that the isolated evaluation of this proteoglycan does not represent an independent prognostic factor in canine CBMTs.</p

Versican expression in canine carcinomas in benign mixed tumours: is there an association with clinical pathological factors, invasion and overall survival?

Background: Components of the extracellular matrix have been studied in an attempt to elucidate the mechanisms involved in the biological behaviour of tumours. The presence of the proteoglycan versican has been strongly associated with cancer development and progression. However, relationship between versican expression and clinical pathological factors and overall survival has not been previously studied in veterinary medicine. Carcinomas in benign mixed tumours (CBMTs) are one of the most common malignant tumours in female canines and can serve as models for studies of tumour progression. The aim of this study was to evaluate the expression of versican in in situ and invasive carcinomatous areas of canine CBMTs and to evaluate possible associations of versican expression with other classic prognostic factors and overall survival. Results: Clinical staging; histological grade determination; immunohistochemical staining for versican, E-cadherin and Ki-67; and confirmation of invasion areas by staining for p63 and smooth muscle α-actin (α-SMA) were performed on 49 canine cases of CBMT. Tumour invasion was considered when suspicious Haematoxylin-Eosin (HE)-stained areas showed a total loss of α-SMA and p63 immunoreactivity. Versican immunoreactivity was less intense in the areas adjacent to the in situ carcinomatous regions, compared to invasive regions, which showed extensive and strong staining. Conclusions: Our data reveal that in canine CBMTs, versican expression differs significantly between invasive and in situ areas, suggesting a role for this molecule in tumour progression. Although a direct relationship exists between versican and invasiveness, our results indicate that the isolated evaluation of this proteoglycan does not represent an independent prognostic factor in canine CBMTs