The Identity Construction of Solo's Adolescent regarding 'Narimo Ing Pandum'

Indonesia is a country that is well-know of its diverse ethnicities, languages, and local wisdom. The nation's potential, however, has gradually been threatened by globalization. Globalization was deemed responsible for not only the socio-cultural and local wisdom crisis but also the spread of consumptive behavior in society, including among adolescents. "Narimo Ing Pandum" (NIP) is one of the Indonesian local wisdom that is useful to minimize the problem. However, it has started to be abandoned, including in Solo and Yogyakarta, as the cities of Javanese cultural centers. This paper attempted to construct the identity of Solonese adolescents within NIP. A qualitative research method and an ethnographic approach were used. The research found 1) how the adolescent defined the characteristic of self with NIP, and 2) that NIP is an active deed of the person. The details of the results are discussed further in the paper

Erratum: Continuous Variable Quantum Key Distribution: Finite-Key Analysis of Composable Security Against Coherent Attacks [Phys. Rev. Lett. 109, 100502 (2012)]

no abstract availabl

Triepitopic Antibody Fusions Inhibit Cetuximab-Resistant BRAF and KRAS Mutant Tumors via EGFR Signal Repression

Dysregulation of epidermal growth factor receptor (EGFR) is a hallmark of many epithelial cancers, rendering this receptor an attractive target for cancer therapy. Much effort has been focused on the development of EGFR-directed antibody-based therapeutics, culminating in the clinical approval of the drugs cetuximab and panitumumab. Unfortunately, the clinical efficacy of these drugs has been disappointingly low, and a particular challenge to targeting EGFR with antibody therapeutics has been resistance, resulting from mutations in the downstream raf and ras effector proteins. Recent work demonstrating antibody cocktail-induced synergistic downregulation of EGFR motivated our design of cetuximab-based antibody–fibronectin domain fusion proteins that exploit downregulation-based EGFR inhibition by simultaneously targeting multiple receptor epitopes. We establish that, among our engineered multiepitopic formats, trans-triepitopic antibody fusions demonstrate optimal efficacy, inducing rapid EGFR clustering and internalization and consequently ablating downstream signaling. The combined effects of EGFR downregulation, ligand competition, and immune effector function conspire to inhibit tumor growth in xenograft models of cetuximab-resistant BRAF and KRAS mutant cancers. Our designed triepitopic constructs have the potential to enhance the efficacy and expand the scope of EGFR-directed therapies, and our multiepitopic may be readily applied to other receptor targets to formulate a new class of antibody-based therapeutics.National Institutes of Health (U.S.) (Grant CA96504)American Society for Engineering Education. National Defense Science and Engineering Graduate Fellowshi

ImpZ: a new photometric redshift code for galaxies and quasars

We present a combined galaxy-quasar approach to template-fitting photometric redshift techniques and show the method to be a powerful one. The code (ImpZ) is presented, developed and applied to two spectroscopic redshift catalogues, namely the Isaac Newton Telescope Wide Angle Survey ELAIS N1 and N2 fields and the Chandra Deep Field North. In particular, optical size information is used to improve the redshift determination. The success of the code is shown to be very good with Delta z/(1+z) constrained to within 0.1 for 92 per cent of the galaxies in our sample. The extension of template-fitting to quasars is found to be reasonable with Delta z/(1+z) constrained to within 0.25 for 68 per cent of the quasars in our sample. Various template extensions into the far-UV are also tested.Comment: 21 pages. MNRAS in press. Minor alterations to match MNRAS final proo

Search for Radiative Decays of Cosmic Background Neutrino using Cosmic Infrared Background Energy Spectrum

We propose to search for the neutrino radiative decay by fitting a photon energy spectrum of the cosmic infrared background to a sum of the photon energy spectrum from the neutrino radiative decay and a continuum. By comparing the present cosmic infrared background energy spectrum observed by AKARI and Spitzer to the photon energy spectrum expected from neutrino radiative decay with a maximum likelihood method, we obatined a lifetime lower limit of $3.1 \times 10^{12}$ to $3.8 \times 10^{12}$ years at 95% confidence level for the third generation neutrino $\nu_3$ in the $\nu_3$ mass range between 50 \mmev and 150 \mmev under the present constraints by the neutrino oscillation measurements. In the left-right symmetric model, the minimum lifetime of $\nu_3$ is predicted to be $1.5 \times 10^{17}$ years for $m_3$ of 50 \mmev. We studied the feasibility of the observation of the neutrino radiative decay with a lifetime of $1.5 \times 10^{17}$ years, by measuring a continuous energy spectrum of the cosmic infrared background

Spin-orbit misalignment in the HD80606 planetary system

We recently reported the photometric and spectroscopic detection of the primary transit of the 111-day-period, eccentric extra-solar planet HD80606 b, at Observatoire de Haute-Provence, France (Moutou et al. 2009). The whole egress of the primary transit and a section of its central part were observed, allowing the measurement of the planetary radius, and evidence for a spin-orbit misalignment through the observation of the Rossiter-McLaughlin anomaly. The ingress having not been observed for this long-duration transit, uncertainties remained in the parameters of the system. We present here a refined, combined analysis of our photometric and spectroscopic data, together with further published radial velocities, ground-based photometry, and Spitzer photometry around the secondary eclipse, as well as new photometric measurements of HD 80606 acquired at Mount Hopkins, Arizona, just before the beginning of the primary transit. Although the transit is not detected in those new data, they provide an upper limit for the transit duration, which narrows down the possible behaviour of the Rossiter-McLaughlin anomaly in the unobserved part of the transit. We analyse the whole data with a Bayesian approach using a Markov-chain Monte Carlo integration on all available information. We find R_p = 0.98 +- 0.03 R_Jup for the planetary radius, and a total primary transit duration of 11.9 +- 1.3 hours from first to fourth contact. Our analysis reinforces the hypothesis of spin-orbit misalignment in this system (alignment excluded at >95 % level), with a positive projected angle between the planetary orbital axis and the stellar rotation (median solution lambda ~ 50 degrees). As HD80606 is a component of a binary system, the peculiar orbit of its planet could result from a Kozai mechanism.Comment: accepted for Publication in Astronomy & Astrophysics, submitted 11 May 200