The effect of photo-ionization on the cooling rates of enriched, astrophysical plasmas

Radiative cooling is central to a wide range of astrophysical problems. Despite its importance, cooling rates are generally computed using very restrictive assumptions, such as collisional ionization equilibrium and solar relative abundances. We simultaneously relax both assumptions and investigate the effects of photo-ionization of heavy elements by the meta-galactic UV/X-ray background and of variations in relative abundances on the cooling rates of optically thin gas in ionization equilibrium. We find that photo-ionization by the meta-galactic background radiation reduces the net cooling rates by up to an order of magnitude for gas densities and temperatures typical of the shock-heated intergalactic medium and proto-galaxies. In addition, photo-ionization changes the relative contributions of different elements to the cooling rates. We conclude that photo-ionization by the ionizing background and heavy elements both need to be taken into account in order for the cooling rates to be correct to order of magnitude. Moreover, if the rates need to be known to better than a factor of a few, then departures of the relative abundances from solar need to be taken into account. We propose a method to compute cooling rates on an element-by-element basis by interpolating pre-computed tables that take photo-ionization into account. We provide such tables for a popular model of the evolving UV/X-ray background radiation, computed using the photo-ionization package CLOUDY.Comment: 10 pages, 6 figures, Accepted for publication in MNRAS. One figure added and minor textual changes made to first version. Downloadable tables and videos available at http://www.strw.leidenuniv.nl/WSS08

Gravitational Heating Helps Make Massive Galaxies Red and Dead

We study the thermal formation history of four simulated galaxies that were shown in Naab et al. (2007) to reproduce a number of observed properties of elliptical galaxies. The temperature of the gas in the galaxies is steadily increasing with decreasing redshift, although much of the gas has a cooling time shorter than the Hubble time. The gas is being heated and kept hot by gravitational heating processes through the release of potential energy from infalling stellar clumps. The energy is dissipated in supersonic collisions of infalling gas lumps with the ambient gas and through the dynamical capturing of satellite systems causing gravitational wakes that transfer energy to the surrounding gas. Furthermore dynamical friction from the infalling clumps pushes out dark matter, lowering the central dark matter density by up to a factor of two from z=3 to z=0. In galaxies in which the late formation history (z<2) is dominated by minor merging and accretion the energy released (E~5x10^{59} ergs) from gravitational feedback is sufficient to form red and dead elliptical galaxies by z~1 even in the absence of supernova and AGN feedback.Comment: 6 pages, 4 figures, accepted to ApJL (minor revisions to match accepted version

Density profiles of dark matter haloes: diversity and dependence on environment

(Abridged) We study the outer density profiles of dark matter haloes predicted by a generalized secondary infall model and observed in a N-body cosmological simulation of a \Lambda CDM model. We find substantial systematic variations in shapes and concentrations of the halo profiles as well as a strong correlation of the profiles with the environment. In the N-body simulation, the average outer slope of the density profiles, \beta (\rho\propto r^{-\beta}), of isolated haloes is \approx 2.9; 68% of these haloes have values of \beta between 2.5 and 3.8. Haloes in dense environments of clusters are more concentrated and exhibit a broad distribution of \beta with values larger than for isolated haloes . Contrary to what one may expect, the haloes contained within groups and galaxy systems are less concentrated and have flatter outer density profiles than the isolated haloes. The concentration decreases with M_h, but its scatter for a given mass is substantial. The mass and circular velocity of the haloes are strongly correlated: M_h \propto V_m^{\alpha} with \alpha ~ 3.3 (isolated) and ~3.5 (haloes in clusters). For M_h=10^12M_sun the rms deviations from these relations are \Delta logM_h=0.12 and 0.18, respectively. Approximately 30% of the haloes are contained within larger haloes or have massive companions (larger than ~0.3 the mass of the current halo) within 3 virial radii. The remaining 70% of the haloes are isolated objects. The distribution of \beta as well as the concentration-mass and M_h-V_m relations for the isolated haloes agree very well with the predictions of our seminumerical approach which is based on a generalization of the secondary infall model and on the extended Press-Schechter formalism.Comment: 14 pages, 11 figures included, uses mn.sty, accepted by MNRAS. Minor modifications, new and updated reference

Interpreting the Evolution of the Size - Luminosity Relation for Disk Galaxies from Redshift 1 to the Present

A sample of very high resolution cosmological disk galaxy simulations is used to investigate the evolution of galaxy disk sizes back to redshift 1 within the Lambda CDM cosmology. Artificial images in the rest frame B band are generated, allowing for a measurement of disk scale lengths using surface brightness profiles as observations would, and avoiding any assumption that light must follow mass as previous models have assumed. We demonstrate that these simulated disks are an excellent match to the observed magnitude - size relation for both local disks, and for disks at z=1 in the magnitude/mass range of overlap. We disentangle the evolution seen in the population as a whole from the evolution of individual disk galaxies. In agreement with observations, our simulated disks undergo roughly 1.5 magnitudes/arcsec^2 of surface brightness dimming since z=1. We find evidence that evolution in the magnitude - size plane varies by mass, such that galaxies with M* > 10^9 M_sun undergo more evolution in size than luminosity, while dwarf galaxies tend to evolve potentially more in luminosity. The disks grow in such a way as to stay on roughly the same stellar mass - size relation with time. Finally, due to an evolving stellar mass - SFR relation, a galaxy at a given stellar mass (or size) at z=1 will reside in a more massive halo and have a higher SFR, and thus a higher luminosity, than a counterpart of the same stellar mass at z=0.Comment: Version resubmitted to ApJ, after referee's comment

Effective-Range Expansion of the Neutron-Deuteron Scattering Studied by a Quark-Model Nonlocal Gaussian Potential

The S-wave effective range parameters of the neutron-deuteron (nd) scattering are derived in the Faddeev formalism, using a nonlocal Gaussian potential based on the quark-model baryon-baryon interaction fss2. The spin-doublet low-energy eigenphase shift is sufficiently attractive to reproduce predictions by the AV18 plus Urbana three-nucleon force, yielding the observed value of the doublet scattering length and the correct differential cross sections below the deuteron breakup threshold. This conclusion is consistent with the previous result for the triton binding energy, which is nearly reproduced by fss2 without reinforcing it with the three-nucleon force.Comment: 21 pages, 6 figures and 6 tables, submitted to Prog. Theor. Phy

Assessment of a continuous blood gas monitoring system in animals during circulatory stress

<p>Abstract</p> <p>Background</p> <p>The study was aimed to determine the measurement accuracy of The CDI™ blood parameter monitoring system 500 (Terumo Cardiovascular Systems Corporation, Ann Arbor MI) in the real-time continuous measurement of arterial blood gases under different cardiocirculatory stress conditions</p> <p>Methods</p> <p>Inotropic stimulation (Dobutamine 2.5 and 5 μg/kg/min), vasoconstriction (Arginine-vasopressin 4, 8 and 16 IU/h), hemorrhage (-10%, -20%, -35%, and -50% of the theoretical volemia), and volume resuscitation were induced in ten swine (57.4 ± 10.7 Kg).Intermittent blood gas assessments were carried out using a routine gas analyzer at any experimental phase and compared with values obtained at the same time settings during continuous monitoring with CDI™ 500 system. The Bland-Altman analysis was employed.</p> <p>Results</p> <p>Bias and precision for pO₂were - 0.06 kPa and 0.22 kPa, respectively (r²= 0.96); pCO₂- 0.02 kPa and 0.15 kPa, respectively; pH -0.001 and 0.01 units, respectively ( r²= 0.96). The analysis showed very good agreement for SO₂(bias 0.04,precision 0.33, r²= 0.95), Base excess (bias 0.04,precision 0.28, r²= 0.98), HCO₃(bias 0.05,precision 0.62, r²= 0.92),hemoglobin (bias 0.02,precision 0.23, r²= 0.96) and K⁺(bias 0.02, precision 0.27, r²= 0.93). The sensor was reliable throughout the experiment during hemodynamic variations.</p> <p>Conclusions</p> <p>Continuous blood gas analysis with the CDI™ 500 system was reliable and it might represent a new useful tool to accurately and timely monitor gas exchange in critically ill patients. Nonetheless, our findings need to be confirmed by larger studies to prove its reliability in the clinical setting.</p

Clinical anticancer drug development: targeting the cyclin-dependent kinases

Cell division involves a cyclical biochemical process composed of several step-wise reactions that have to occur once per cell cycle. Dysregulation of cell division is a hallmark of all cancers. Genetic and epigenetic mechanisms frequently result in deranged expression and/or activity of cell-cycle proteins including the cyclins, cyclin-dependent kinases (Cdks), Cdk inhibitors and checkpoint control proteins. The critical nature of these proteins in cell cycling raises hope that targeting them may result in selective cytotoxicity and valuable anticancer activity

Reionisation, chemical enrichment and seed black holes from the first stars: is Population III important?

We investigate the effects of a top-heavy stellar initial mass function on the reionisation history of the intergalactic medium (IGM). We use cosmological simulations that include self-consistently the feedback from ionising radiation, H_2 dissociating radiation and supernova (SN) explosions. We find that it is difficult to reionise the IGM at z_rei>10 with stellar sources even after making extreme assumptions. If star formation in 10^9 M_\odot galaxies is not suppressed by SN explosions, the optical depth to Thomson scattering is tau_e< 0.13. If we allow for the normal energy input from SNe or if pair-instability SNe are dominant, we find taue<0.09. Assuming normal yields for the first stars (popIII), the mean metallicity of the IGM is already Z/Z_\odot=2x10^-3 (10^-3<Z/Z_\odot<1 in overdense regions) when the IGM mean ionisation fraction is less than 10%. For these reasons popIII stars cannot contribute significantly to reionisation unless the mechanical energy input from SNe is greatly reduced and either the metal yield or the mixing efficiency is reduced by a factor of 1000. Both problems have a solution if popIII stars collapse to black holes. This can happen if, having masses M_*< 130 M_\odot, they are characterised by heavy element fall-back or if, having masses M_*>260 M_\odot, they collapse directly onto black holes without exploding as SNe.If metal-poor stars are initially important and collapse to black holes is the typical outcome, then the secondary emission of ionising radiation from accretion on SN induced seed black holes, might be more important than the primary emission. Surprisingly, including feedback effects, we estimate that a warm dark matter scenario (with particle mass of 1.25 keV) reduces tau_e by only approximately 10%.[abridged]Comment: Accepted for publication in MNRAS. 13 pages, including 9 figures and 2 table

The Evolution of Compact Binary Star Systems

We review the formation and evolution of compact binary stars consisting of white dwarfs (WDs), neutron stars (NSs), and black holes (BHs). Binary NSs and BHs are thought to be the primary astrophysical sources of gravitational waves (GWs) within the frequency band of ground-based detectors, while compact binaries of WDs are important sources of GWs at lower frequencies to be covered by space interferometers (LISA). Major uncertainties in the current understanding of properties of NSs and BHs most relevant to the GW studies are discussed, including the treatment of the natal kicks which compact stellar remnants acquire during the core collapse of massive stars and the common envelope phase of binary evolution. We discuss the coalescence rates of binary NSs and BHs and prospects for their detections, the formation and evolution of binary WDs and their observational manifestations. Special attention is given to AM CVn-stars -- compact binaries in which the Roche lobe is filled by another WD or a low-mass partially degenerate helium-star, as these stars are thought to be the best LISA verification binary GW sources.Comment: 105 pages, 18 figure