Marking complex assignments using peer assessment with an electronic voting system and an automated feedback tool

The work described in this paper relates to the development and use of a range of initiatives in order to mark complex masters' level assignments related to the development of computer web applications. In the past such assignments have proven difficult to mark since they assess a range of skills including programming, human computer interaction and design. Based on the experience of several years marking such assignments, the module delivery team decided to adopt an approach whereby the students marked each other's practical work using an electronic voting system (EVS). The results of this are presented in the paper along with statistical comparison with the tutors' marking, providing evidence for the efficacy of the approach. The second part of the assignment related to theory and documentation. This was marked by the tutors using an automated feedback tool. It was found that the time to mark the work was reduced by more than 30% in all cases compared to previous years. More importantly it was possible to provide good quality individual feedback to learners rapidly. Feedback was delivered to all within three weeks of the test submission datePeer reviewe

The use of electronic voting and peer assessment to encourage the development of higher order thinking skills in learners

In the research reported here, electronic voting and peer assessment were used with 215 first year computer science and information technology undergraduates undertaking an electronic media design module. In previous years it proved difficult for learners following this module to develop good quality practical skills resulting in poor results in practical tests. In this study, the module delivery team used electronic voting and a form of peer assessment in order to motivate learners and to engage them more deeply in learning. It was hypothesised that this would improve higher order thinking skills and lead to improved performance in practical work. A significant improvement in performance of 6% was achieved (p<0.001) as compared to previous years. We were able to show that the most likely reason for this was the use of electronic voting systems and peer assessment. In the concluding section of the paper we discuss some issues related to this finding and our teaching approachPeer reviewe

Identifying and preventing health problems among young drug-misusing offenders

Purpose – The purpose of this paper is to identify the health problems and treatment needs of drug-misusing offenders and to draw out the implications of the findings for health education and prevention. Design/methodology/approach – This analysis is based on data collected as part of the New English and Welsh Arrestee Drug Abuse Monitoring (NEW-ADAM) programme. The survey was based on interviews and urine sample collection with over 3,000 arrestees. Findings – The research found that young arrestees experienced a wide range of drug-related and general health problems. The implications of this are discussed in the context of programmes implemented as part of the government’s drug strategy. Originality/value – The NEW-ADAM surveys provide an original source of information on the drug and general health needs of young people at the first point of entry in the criminal justice system

A Feasibility Study on the Automation of Domestic Airline Passenger Customer Service Check-In Procedures for FAR Part 121 Carriers

This study was conducted in an attempt to determine whether airlines can benefit from a fully automated customer service system which will be used by major, Part 121, operators for domestic travel purposes only. The proposed system will be designed to alleviate airport terminals check-in counter congestion and improve customer service personnel effectiveness and efficiency. Domestic traffic is expected to increase by 50 percent by the year 2004. An Automatic Ticketing and Baggage (ATB) system will allow passengers to process all flight related transactions only once. A self checking-in system allows a passenger to obtain boarding passes and destination bag tags. From there the passenger simply boards the aircraft. This can be accomplished without the interaction of airline employees who can be deployed to handle more critical matters. With the introduction of an automated system, it is anticipated that there will be little need for additional passenger processing facilities such as land-side expansion or other major infrastructure. Employing a questionnaire survey, the author attempted to determine if a need exists for such a system. The automated system will be used by frequent fliers, particularly business travelers and other seasoned passengers who travel under time constraints. Current check-in procedures can be time consuming and stressful. The user-friendly system will be located at strategic points where high utilization will be expected. Possible locations for an automated check-in system include curbside check-in, strategic points within the terminal buildings, and areas within the sterile holding area. Vendors are available that can provide the already existing hardware and software needed to implement the system

Akt isoforms in vascular disease.

The mammalian serine/threonine Akt kinases comprise three closely related isoforms: Akt1, Akt2 and Akt3. Akt activation has been implicated in both normal and disease processes, including in development and metabolism, as well as cancer and cardiovascular disease. Although Akt signalling has been identified as a promising therapeutic target in cancer, its role in cardiovascular disease is less clear. Importantly, accumulating evidence suggests that the three Akt isoforms exhibit distinct tissue expression profiles, localise to different subcellular compartments, and have unique modes of activation. Consistent with in vitro findings, genetic studies in mice show distinct effects of individual Akt isoforms on the pathophysiology of cardiovascular disease. This review summarises recent studies of individual Akt isoforms in atherosclerosis, vascular remodelling and aneurysm formation, to provide a comprehensive overview of Akt function in vascular disease.This work was supported by British Heart Foundation grants PG/11/ 112/29272, RG/08/009/25841 and RG/13/14/30314, and the Cambridge NIHR Biomedical Research Centre.This is the final version of the article. It was first published by Elsevier at http://www.sciencedirect.com/science/article/pii/S1537189115000397

Tissue Inhibitor of Metalloproteinase–3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells

Over expression of Tissue Inhibitor of Metalloproteinases-3 (TIMP-3) in vascular smooth muscle cells (VSMCs) induces apoptosis and reduces neointima formation occurring after saphenous vein interposition grafting or coronary stenting. In studies to address the mechanism of TIMP-3-driven apoptosis in human VSMCs we find that TIMP-3 increased activation of caspase-8 and apoptosis was inhibited by expression of Cytokine response modifier A (CrmA) and dominant negative FAS-Associated protein with Death Domain (FADD). TIMP-3 induced apoptosis did not cause mitochondrial depolarisation, increase activation of caspase-9 and was not inhibited by over-expression of B-cell Lymphoma 2 (Bcl2), indicating a mitochondrial independent/type-I death receptor pathway. TIMP-3 increased levels of the First Apoptosis Signal receptor (FAS) and depletion of FAS with shRNA showed TIMP-3-induced apoptosis was FAS dependent. TIMP-3 induced formation of the Death-Inducing Signalling Complex (DISC), as detected by immunoprecipitation and by immunofluorescence. Cellular-FADD-like IL-1 converting enzyme-Like Inhibitory Protein (c-FLIP) localised with FAS at the cell periphery in the absence of TIMP-3 and this localisation was lost on TIMP-3 expression with c-FLIP adopting a perinuclear localisation. Although TIMP-3 inhibited FAS shedding, this did not increase total surface levels of FAS but instead increased FAS levels within localised regions at the cell surface. A Disintegrin And Metalloproteinase 17 (ADAM17) is inhibited by TIMP-3 and depletion of ADAM17 with shRNA significantly decreased FAS shedding. However ADAM17 depletion did not induce apoptosis or replicate the effects of TIMP-3 by increasing localised clustering of cell surface FAS. ADAM17-depleted cells could activate caspase-3 when expressing levels of TIMP-3 that were otherwise sub-apoptotic, suggesting a partial role for ADAM17 mediated ectodomain shedding in TIMP-3 mediated apoptosis. We conclude that TIMP-3 induced apoptosis in VSMCs is highly dependent on FAS and is associated with changes in FAS and c-FLIP localisation, but is not solely dependent on shedding of the FAS ectodomain

Towards a More User Friendly Technique for Predicting Photovoltaic Energy Output

Several factors impact the power output from solar photovoltaic (PV) modules. Some are deterministic and controllable and others are uncontrollable (e.g., meteorological conditions), yet critical to performance. The objective of this paper is to assess the relationship between the meteorological variables and the power output of a mono silicon PV module using Multiple Linear Regression modelling. The approach involved exposing one mono-silicon photovoltaic module to the open atmosphere for a period of time and measuring the electrical energy output as a function of natural variation in the meteorological factors. A regression model for the power output was developed and significant variables identified. The model derived for this material grade of silicon tended to match the validation data more closely for clear skies, but not as accurate for times of cloud cover. Results of this study will provide useful design and application insight on critical factors that impact the energy capabilities of crystalline silicon PV modules. The analysis was simultaneously targeted to a nontechnical audience, so that home owners interested in installing photovoltaic arrays on their roofs can have a simpler, user friendly method by which to determine energy output for various atmospheric conditions