5,045 research outputs found
Simulation and performance of an artificial retina for 40 MHz track reconstruction
We present the results of a detailed simulation of the artificial retina
pattern-recognition algorithm, designed to reconstruct events with hundreds of
charged-particle tracks in pixel and silicon detectors at LHCb with LHC
crossing frequency of . Performances of the artificial retina
algorithm are assessed using the official Monte Carlo samples of the LHCb
experiment. We found performances for the retina pattern-recognition algorithm
comparable with the full LHCb reconstruction algorithm.Comment: Final draft of WIT proceedings modified according to JINST referee's
comment
The artificial retina for track reconstruction at the LHC crossing rate
We present the results of an R&D study for a specialized processor capable of
precisely reconstructing events with hundreds of charged-particle tracks in
pixel and silicon strip detectors at , thus suitable for
processing LHC events at the full crossing frequency. For this purpose we
design and test a massively parallel pattern-recognition algorithm, inspired to
the current understanding of the mechanisms adopted by the primary visual
cortex of mammals in the early stages of visual-information processing. The
detailed geometry and charged-particle's activity of a large tracking detector
are simulated and used to assess the performance of the artificial retina
algorithm. We find that high-quality tracking in large detectors is possible
with sub-microsecond latencies when the algorithm is implemented in modern,
high-speed, high-bandwidth FPGA devices.Comment: 3 pages, 3 figures, ICHEP14. arXiv admin note: text overlap with
arXiv:1409.089
A Specialized Processor for Track Reconstruction at the LHC Crossing Rate
We present the results of an R&D study of a specialized processor capable of
precisely reconstructing events with hundreds of charged-particle tracks in
pixel detectors at 40 MHz, thus suitable for processing LHC events at the full
crossing frequency. For this purpose we design and test a massively parallel
pattern-recognition algorithm, inspired by studies of the processing of visual
images by the brain as it happens in nature. We find that high-quality tracking
in large detectors is possible with sub-s latencies when this algorithm is
implemented in modern, high-speed, high-bandwidth FPGA devices. This opens a
possibility of making track reconstruction happen transparently as part of the
detector readout.Comment: Presented by G.Punzi at the conference on "Instrumentation for
Colliding Beam Physics" (INSTR14), 24 Feb to 1 Mar 2014, Novosibirsk, Russia.
Submitted to JINST proceeding
First prototype of a silicon tracker using an artificial retina for fast track finding
We report on the R\&D for a first prototype of a silicon tracker based on an
alternative approach for fast track finding. The working principle is inspired
from neurobiology, in particular by the processing of visual images by the
brain as it happens in nature. It is based on extensive parallelisation of data
distribution and pattern recognition. In this work we present the design of a
practical device that consists of a telescope based on single-sided silicon
detectors; we describe the data acquisition system and the implementation of
the track finding algorithms using available digital logic of commercial FPGA
devices. Tracking performance and trigger capabilities of the device are
discussed along with perspectives for future applications.Comment: 9 pages, 7 figures, Technology and Instrumentation in Particle
Physics 2014 (TIPP 2014), conference proceeding
The artificial retina processor for track reconstruction at the LHC crossing rate
We present results of an R&D study for a specialized processor capable of
precisely reconstructing, in pixel detectors, hundreds of charged-particle
tracks from high-energy collisions at 40 MHz rate. We apply a highly parallel
pattern-recognition algorithm, inspired by studies of the processing of visual
images by the brain as it happens in nature, and describe in detail an
efficient hardware implementation in high-speed, high-bandwidth FPGA devices.
This is the first detailed demonstration of reconstruction of offline-quality
tracks at 40 MHz and makes the device suitable for processing Large Hadron
Collider events at the full crossing frequency.Comment: 4th draft of WIT proceedings modified according to JINST referee's
comments. 10 pages, 6 figures, 2 table
The clinical management of children with achondroplasia in Italy: results of clinician and parent/caregiver surveys
Purpose: This study aimed to assess the real-world management of achondroplasia in Italy. Methods: Two online surveys addressed to (1) parents/caregivers of individuals with achondroplasia and (2) Italian clinicians managing individuals with achondroplasia were conducted to assess real-world perspectives on achondroplasia management. Both surveys collected data on either patient or clinician demographics, details on diagnoses and referrals, disease complications, and views/experiences with limb lengthening surgery. Results: In total, 42 parents/caregivers and 19 clinicians (from 18 hospitals) completed the surveys. According to parents/caregivers, achondroplasia diagnosis was most commonly made in the third trimester of gestation (55% of respondents), with a genetic test performed to confirm the diagnosis in all but one case. In contrast, the clinicians indicated that, while achondroplasia was typically suspected during the prenatal period (78%), diagnosis was more frequently confirmed postnatally (72%). Parents/caregivers reported that the greatest impact of achondroplasia-related complications occurred in their children between the ages of 2-5 years. The most significant complications were otitis, sleep apnoea, stenosis of the foramen magnum or pressure on the spinal cord, and hearing difficulties. Lengthening surgery had been presented as a treatment option to 92% of responding parents/caregivers, with 76% of clinicians viewing surgery favourably. Typically, clinicians' reasons for suggesting limb lengthening surgery were to improve patient quality of life, increase patient autonomy and self-acceptance, improve trunk-limb disproportion, short stature and walking, and ensure that all possible treatment options had been presented to the parents/caregivers. Conclusion: This survey provides insight into the real-world management of individuals with achondroplasia in Italy
Dual-readout Calorimetry
The RD52 Project at CERN is a pure instrumentation experiment whose goal is
to understand the fundamental limitations to hadronic energy resolution, and
other aspects of energy measurement, in high energy calorimeters. We have found
that dual-readout calorimetry provides heretofore unprecedented information
event-by-event for energy resolution, linearity of response, ease and
robustness of calibration, fidelity of data, and particle identification,
including energy lost to binding energy in nuclear break-up. We believe that
hadronic energy resolutions of {\sigma}/E 1 - 2% are within reach for
dual-readout calorimeters, enabling for the first time comparable measurement
preci- sions on electrons, photons, muons, and quarks (jets). We briefly
describe our current progress and near-term future plans. Complete information
on all aspects of our work is available at the RD52 website
http://highenergy.phys.ttu.edu/dream/.Comment: 10 pages, 10 figures, Snowmass White pape
The cooling of atomic and molecular gas in DR21
We present an overview of a high-mass star formation region through the major
(sub-)mm, and far-infrared cooling lines to gain insight into the physical
conditions and the energy budget of the molecular cloud. We used the KOSMA 3m
telescope to map the core () of the Galactic star forming region
DR 21/DR 21 (OH) in the Cygnus X region in the two fine structure lines of
atomic carbon CI and four mid- transitions of CO and CO, and CS
J=7\TO6. These observations have been combined with FCRAO J=1\TO0
observations of CO and CO. Five positions, including DR21, DR21
(OH), and DR21 FIR1, were observed with the ISO/LWS grating spectrometer in the
\OI 63 and 145 m lines, the \CII 158 m line, and four high- CO
lines. We discuss the intensities and line ratios at these positions and apply
Local Thermal Equilibrium (LTE) and non-LTE analysis methods in order to derive
physical parameters such as masses, densities and temperatures. The CO line
emission has been modeled up to J=20. From non-LTE modeling of the low- to
high- CO lines we identify two gas components, a cold one at temperatures of
T_\RM{kin}\sim 30-40 K, and one with T_\RM{kin}\sim 80-150 K at a local
clump density of about n(H) cm. While the cold
quiescent component is massive containing typically more than 94 % of the mass,
the warm, dense, and turbulent gas is dominated by mid- and high- CO line
emission and its large line widths. The medium must be clumpy with a
volume-filling of a few percent. The CO lines are found to be important for the
cooling of the cold molecular gas, e.g. at DR21 (OH). Near the outflow of the
UV-heated source DR21, the gas cooling is dominated by line emission of atomic
oxygen and of CO
The artificial retina for track reconstruction at the LHC crossing rate
We present the results of an R&D study for a specialized processor capable of precisely reconstructing events with hundreds of charged-particle tracks in pixel and silicon strip detectors at 40 MHz, thus suitable for processing LHC events at the full crossing frequency. For this purpose we design and test a massively parallel pattern-recognition algorithm, inspired to the current understanding of the mechanisms adopted by the primary visual cortex of mammals in the early stages of visual-information processing. The detailed geometry and charged-particle's activity of a large tracking detector are simulated and used to assess the performance of the artificial retina algorithm. We find that high-quality tracking in large detectors is possible with sub-microsecond latencies when the algorithm is implemented in modern, high-speed, high-bandwidth FPGA devices
Melorheostosis and Osteopoikilosis Clinical and Molecular Description of an Italian Case Series
Melorheostosis (MEL) is an uncommon, sclerosing disease, characterised by hyperostosis of long bones, resembling the flowing of candle wax. The disease is sporadic and the pathogenesis is still poorly understood. Occasionally, the same family can include individuals with MEL and Osteopoikilosis (OPK), a disease characterised by multiple round foci of increased bone density. LEMD3 gene mutations are related to OPK and Buschke\u2013Ollendorff Syndrome, a genetic condition in which an association between MEL, OPK and skin lesions is observed. In rare cases, LEMD3 mutations and recently mosaic MAP2K1 gene mutations have been correlated to MEL suggesting that somatic mosaicism could be causative of the disease. In this study, we described the clinical, radiological and molecular findings of 19 individuals with MEL and 8 with OPK and compared the results to the medical literature. The molecular analyses of this case series corroborate the available data in the medical literature, indicating that LEMD3 germline mutations are not a major cause of isolated MEL and reporting five further cases of OPK caused by LEMD3 germline mutations
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