53,789 research outputs found

    Biophysical aspects of radiation carcinogenesis

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    Cosmic Microwave Background constraints of decaying dark matter particle properties

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    If a component of cosmological dark matter is made up of massive particles - such as sterile neutrinos - that decay with cosmological lifetime to emit photons, the reionization history of the universe would be affected, and cosmic microwave background anisotropies can be used to constrain such a decaying particle model of dark matter. The optical depth depends rather sensitively on the decaying dark matter particle mass m_{dm}, lifetime tau_{dm}, and the mass fraction of cold dark matter f that they account for in this model. Assuming that there are no other sources of reionization and using the WMAP 7-year data, we find that 250 eV < m_{dm} < 1 MeV, whereas 2.23*10^3 yr < tau_{dm} < 1.23*10^18 yr. The best fit values for m_{dm} and tau_{dm}/f are 17.3 keV and 2.03*10^16 yr respectively.Comment: 17 pages, 3 figure

    DNA nano-mechanics: how proteins deform the double helix

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    It is a standard exercise in mechanical engineering to infer the external forces and torques on a body from its static shape and known elastic properties. Here we apply this kind of analysis to distorted double-helical DNA in complexes with proteins. We extract the local mean forces and torques acting on each base-pair of bound DNA from high-resolution complex structures. Our method relies on known elastic potentials and a careful choice of coordinates of the well-established rigid base-pair model of DNA. The results are robust with respect to parameter and conformation uncertainty. They reveal the complex nano-mechanical patterns of interaction between proteins and DNA. Being non-trivially and non-locally related to observed DNA conformations, base-pair forces and torques provide a new view on DNA-protein binding that complements structural analysis.Comment: accepted for publication in JCP; some minor changes in response to review 18 pages, 5 figure + supplement: 4 pages, 3 figure

    Clustering Memes in Social Media

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    The increasing pervasiveness of social media creates new opportunities to study human social behavior, while challenging our capability to analyze their massive data streams. One of the emerging tasks is to distinguish between different kinds of activities, for example engineered misinformation campaigns versus spontaneous communication. Such detection problems require a formal definition of meme, or unit of information that can spread from person to person through the social network. Once a meme is identified, supervised learning methods can be applied to classify different types of communication. The appropriate granularity of a meme, however, is hardly captured from existing entities such as tags and keywords. Here we present a framework for the novel task of detecting memes by clustering messages from large streams of social data. We evaluate various similarity measures that leverage content, metadata, network features, and their combinations. We also explore the idea of pre-clustering on the basis of existing entities. A systematic evaluation is carried out using a manually curated dataset as ground truth. Our analysis shows that pre-clustering and a combination of heterogeneous features yield the best trade-off between number of clusters and their quality, demonstrating that a simple combination based on pairwise maximization of similarity is as effective as a non-trivial optimization of parameters. Our approach is fully automatic, unsupervised, and scalable for real-time detection of memes in streaming data.Comment: Proceedings of the 2013 IEEE/ACM International Conference on Advances in Social Networks Analysis and Mining (ASONAM'13), 201

    The Struve-Sahade effect in the optical spectra of O-type binaries I. Main-sequence systems

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    We present a spectroscopic analysis of four massive binary systems that are known or are good candidates to display the Struve-Sahade effect (defined as the apparent strengthening of the secondary spectrum of the binary when the star is approaching, and the corresponding weakening of the lines when it is receding). We use high resolution optical spectra to determine new orbital solutions and spectral types of HD 165052, HD 100213, HD 159176 and DH Cep. As good knowledge of the fundamental parameters of the considered systems is necessary to examine the Struve-Sahade effect. We then study equivalent width variations in the lines of both components of these binaries during their orbital cycle. In the case of these four systems, variations appear in the equivalent widths of some lines during the orbital cycle, but the definition given above can any longer be valid, since it is now clear that the effect modifies the primary spectrum as much as the secondary spectrum. Furthermore, the lines affected, and the way in which they are affected, depend on the considered system. For at least two of them (HD 100213 and HD 159176) these variations probably reflect the ellipsoidal variable nature of the system.Comment: 12 pages, 20 figures, in press A&

    Not all the bots are created equal:the Ordering Turing Test for the labelling of bots in MMORPGs

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    This article contributes to the research on bots in Social Media. It takes as its starting point an emerging perspective which proposes that we should abandon the investigation of the Turing Test and the functional aspects of bots in favor of studying the authentic and cooperative relationship between humans and bots. Contrary to this view, this article argues that Turing Tests are one of the ways in which authentic relationships between humans and bots take place. To understand this, this article introduces the concept of Ordering Turing Tests: these are sort of Turing Tests proposed by social actors for purposes of achieving social order when bots produce deviant behavior. An Ordering Turing Test is method for labeling deviance, whereby social actors can use this test to tell apart rule-abiding humans and rule-breaking bots. Using examples from Massively Multiplayer Online Role-Playing Games, this article illustrates how Ordering Turing Tests are proposed and justified by players and service providers. Data for the research comes from scientific literature on Machine Learning proposed for the identification of bots and from game forums and other player produced paratexts from the case study of the game Runescape

    A 4-Component Dirac Theory of Ionization of Hydrogen Molecular Ion in a Super-Intense Laser Field

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    In this paper a 4-component Dirac theory of ionization of hydrogen molecular ion in a super-intense laser field is developed. Simple analytic expressions for the spin specific as well as the total ionization currents emitted from the ground state of the ion are derived. The results are given for all polarization and finite propagation vectors of the field. They apply for inner-shell ionization of analogous heavier molecular ions as well. The presence of molecular two-slit interference effect, first found in the non-relativistic case, and the spin-flip ionization current, and an asymmetry of the up- and down-spin currents similar to that predicted in the atomic case, are found also to hold for the present relativistic molecular ionic case. Finally, the possibility of controlling the dominant spin currents by selecting the handedness of a circularly polarized incident laser field is pointed out.Comment: 7 pages, no figure

    Resonant enhancements of high-order harmonic generation

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    Solving the one-dimensional time-dependent Schr\"odinger equation for simple model potentials, we investigate resonance-enhanced high-order harmonic generation, with emphasis on the physical mechanism of the enhancement. By truncating a long-range potential, we investigate the significance of the long-range tail, the Rydberg series, and the existence of highly excited states for the enhancements in question. We conclude that the channel closings typical of a short-range or zero-range potential are capable of generating essentially the same effects.Comment: 7 pages revtex, 4 figures (ps files
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