Reflexões sobre a prática do residente Terapeuta Ocupacional na Estratégia Saúde da Família no município de São Carlos

This study, based on dialectical hermeneutics, investigated the view of occupational therapists posgraduates at University of São Carlos about their practices. During the residence, they worked in a Unit of Family Healthcare in which they are inserted in a matrix organization model and they had permanent education and research based in practice, learning about management of health services, individual and collective care. Seven graduates, who concluded the residence between 2007 and 2011, answered an on-line questionnaire. This material was grouped in accordance to comprehensive and critical social reality knowledge based in the pedagogic project and residence theory. Although each student has had different view, everyoneexperienced and recognized, generally, the practice according to Family Health Strategy precepts: comprehensive health care, interdisciplinary, intersectionality, networking, social control, co-responsibility, autonomy and protagonism. Moreover, the answers demonstrated an association between care (individual and collective) to occupational therapy center of knowledge, and groups management and permanent education were associated to community health. In conclusion, the posgraduates recognized the residence as a fundamental experience to their personal and professional formation.O olhar dos residentes egressos de Terapia Ocupacional sobre suas práticas na Residência Multiprofissional em Saúde da Família e Comunidade da UFSCar foi o objetivo deste estudo. Durante o programa de pós-graduação “lato sensu”, de ensino em serviço, os residentes desenvolvem competências de cuidado individual e coletivo, gestão, educação permanente e pesquisa, na lógica do apoio matricial, inseridos em Unidades de Saúde da Família do município. Responderam a um questionário on-line, sete dos oito residentes formados de 2007 a 2011. O material empírico foi agrupado em blocos a partir de um entendimento da hermenêutica dialética em diálogo com o referencial teórico e o projeto pedagógico da residência. Embora com diferenças, todos os residentes puderam reconhecer, de forma ampliada, as práticas e os preceitos da Estratégia Saúde da Família. Nos relatos, associaram o cuidado individual e coletivo ao núcleo de saber da Terapia Ocupacional, e associaram as ações coletivas, de gestão e de educação permanente, ao campo de saber da Saúde Coletiva. Os egressos reconheceram a residência como fundamental para sua formação pessoal e profissional

High anti-SARS-CoV-2 antibody seroconversion rates before the second wave in Manaus, Brazil, and the protective effect of social behaviour measures: results from the prospective DETECTCoV-19 cohort

Background: The city of Manaus, Brazil, has seen two collapses of the health system due to the COVID-19 pandemic. We report anti-SARS-CoV-2 nucleocapsid IgG antibody seroconversion rates and associated risk factors in Manaus residents before the second wave of the epidemic in Brazil. Methods: A convenience sample of adult (aged ≥18 years) residents of Manaus was recruited through online and university website advertising into the DETECTCoV-19 study cohort. The current analysis of seroconversion included a subgroup of DETECTCoV-19 participants who had at least two serum sample collections separated by at least 4 weeks between Aug 19 and Oct 2, 2020 (visit 1), and Oct 19 and Nov 27, 2020 (visit 2). Those who reported (or had no data on) having a COVID-19 diagnosis before visit 1, and who were positive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at visit 1 were excluded. Using an in-house ELISA, the reactivity index (RI; calculated as the optical density ratio of the sample to the negative control) for serum anti-SARS-CoV-2 nucleocapsid IgG antibodies was measured at both visits. We calculated the incidence of seroconversion (defined as RI values ≤1·5 at visit 1 and ≥1·5 at visit 2, and a ratio >2 between the visit 2 and visit 1 RI values) during the study period, as well as incidence rate ratios (IRRs) through cluster-corrected and adjusted Poisson regression models to analyse associations between seroconversion and variables related to sociodemographic characteristics, health access, comorbidities, COVID-19 exposure, protective behaviours, and symptoms. Findings: 2496 DETECTCoV-19 cohort participants returned for a follow-up visit between Oct 19 and Nov 27, 2020, of whom 204 reported having COVID-19 before the first visit and 24 had no data regarding previous disease status. 559 participants were seropositive for anti-SARS-CoV-2 nucleocapsid IgG antibodies at baseline. Of the remaining 1709 participants who were seronegative at baseline, 71 did not meet the criteria for seroconversion and were excluded from the analyses. Among the remaining 1638 participants who were seronegative at baseline, 214 showed seroconversion at visit 2. The seroconversion incidence was 13·06% (95% CI 11·52–14·79) overall and 6·78% (5·61–8·10) for symptomatic seroconversion, over a median follow-up period of 57 days (IQR 54–61). 48·1% of seroconversion events were estimated to be asymptomatic. The sample had higher proportions of affluent and higher-educated people than those reported for the Manaus city population. In the fully adjusted and corrected model, risk factors for seroconversion before visit 2 were having a COVID-19 case in the household (IRR 1·49 [95% CI 1·21–1·83]), not wearing a mask during contact with a person with COVID-19 (1·25 [1·09–1·45]), relaxation of physical distancing (1·31 [1·05–1·64]), and having flu-like symptoms (1·79 [1·23–2·59]) or a COVID-19 diagnosis (3·57 [2·27–5·63]) between the first and second visits, whereas working remotely was associated with lower incidence (0·74 [0·56–0·97]). Interpretation: An intense infection transmission period preceded the second wave of COVID-19 in Manaus. Several modifiable behaviours increased the risk of seroconversion, including non-compliance with non-pharmaceutical interventions measures such as not wearing a mask during contact, relaxation of protective measures, and non-remote working. Increased testing in high-transmission areas is needed to provide timely information about ongoing transmission and aid appropriate implementation of transmission mitigation measures. Funding: Ministry of Education, Brazil; Fundação de Amparo à Pesquisa do Estado do Amazonas; Pan American Health Organization (PAHO)/WHO.World Health OrganizationRevisión por pare

About the therapist occupational Residence practice at family healthcare strategy in São Carlos

O olhar dos residentes egressos de Terapia Ocupacional sobre suas práticas na Residência Multiprofissional em Saúde da Família e Comunidade da UFSCar foi o objetivo deste estudo. Durante o programa de pós-graduação “lato sensu”, de ensino em serviço, os residentes desenvolvem competências de cuidado individual e coletivo, gestão, educação permanente e pesquisa, na lógica do apoio matricial, inseridos em Unidades de Saúde da Família do município. Responderam a um questionário on-line, sete dos oito residentes formados de 2007 a 2011. O material empírico foi agrupado em blocos a partir de um entendimento da hermenêutica dialética em diálogo com o referencial teórico e o projeto pedagógico da residência. Embora com diferenças, todos os residentes puderam reconhecer, de forma ampliada, as práticas e os preceitos da Estratégia Saúde da Família. Nos relatos, associaram o cuidado individual e coletivo ao núcleo de saber da Terapia Ocupacional, e associaram as ações coletivas, de gestão e de educação permanente, ao campo de saber da Saúde Coletiva. Os egressos reconheceram a residência como fundamental para sua formação pessoal e profissional.This study, based on dialectical hermeneutics, investigated the view of occupational therapists posgraduates at University of São Carlos about their practices. During the residence, they worked in a Unit of Family Healthcare in which they are inserted in a matrix organization model and they had permanent education and research based in practice, learning about management of health services, individual and collective care. Seven graduates, who concluded the residence between 2007 and 2011, answered an on-line questionnaire. This material was grouped in accordance to comprehensive and critical social reality knowledge based in the pedagogic project and residence theory. Although each student has had different view, everyoneexperienced and recognized, generally, the practice according to Family Health Strategy precepts: comprehensive health care, interdisciplinary, intersectionality, networking, social control, co-responsibility, autonomy and protagonism. Moreover, the answers demonstrated an association between care (individual and collective) to occupational therapy center of knowledge, and groups management and permanent education were associated to community health. In conclusion, the posgraduates recognized the residence as a fundamental experience to their personal and professional formation

Morfoanatomia foliar de Brachiaria decumbens Stapf, coletada na zona rural de Lavras, estado de Minas Gerais, Brasil

The Brachiaria grass is the most cultivated in Brazil, efficiently used in several kinds of cattle breeding. It�s ecological and economic importance stimulate this work that aim to study the leaf morphoanatomy of Brachiaria decumbens Stapf. Cross and paradermal sections cuts were made in the region of the median leaf and, after that, they were submitted to discoloration in commercial sodium hypochlorite and colored with Safranin and Astra Blue. We found that this specie has vascular bundles of different sizes, organized throughout the mesophyll. Epidermal structures like trichomes, possibly protection agents and the sinuosity of their cells were identified as an auxiliary mechanical adaptation of the water flow.A Brachiaria é o gênero de pastagem mais cultivado no território brasileiro, sendo usado de diversas formas na criação de animais e de maneira bem eficiente. Sua importância econômica e ecológica motivou o presente estudo que teve como objetivo descrever a morfoanatomia foliar da Brachiaria decumbens Stapf. Para tal foram feitos cortes transversais e paradérmicos na região mediana da lâmina foliar, sendo os mesmos, submetidos à descoloração em hipoclorito de sódio comercial e corados com Safranina e Azul de Astra. Verificou-se que a espécie em questão apresenta feixes vasculares de diferentes calibres, organizados por todo o mesofilo. Apêndices epidérmicos como tricomas, possivelmente agentes de proteção, e a sinuosidade das células epidérmicas foram identificados como auxiliares da adaptação mecânica a entrada e saída de água.Brachiaria es el género de pasto más cultivado en el territorio brasileño, siendo usado de diversas formas y de manera muy eficiente en la cría de animals. Su importancia económica y ecológica motivó el presente estudio que tuvo como objetivo describir la morfoanatomía foliar de Brachiaria decumbens Stapf. Para esto se hicieron cortes transversales y paradérmicos en la región mediana de la lámina foliar, siendo los mismos sometidos a decoloración en hipoclorito de sodio comercial y coloreados con Safranina y Azul de Astra. Se verificó que la espécie presenta haces vasculares de diferentes tamaños, organizados a través del mesofilo, apéndices epidérmicos como tricomas, posiblemente agentes de protección y sinuosidad de células epidérmicas se identificaron como auxiliares de la adaptación mecánica a la entrada y salida de agua

Morfoanatomía foliar de Brachiaria decumbens Stapf, colectada en la zona rural de Lavras, estado de Minas Gerais, Brasil

The Brachiaria grass is the most cultivated in Brazil, efficiently used in several kinds of cattle breeding. It’s ecological and economic importance stimulate this work that aim to study the leaf morphoanatomy of Brachiaria decumbens Stapf. Cross and paradermal sections cuts were made in the region of the median leaf and, after that, they were submitted to discoloration in commercial sodium hypochlorite and colored with Safranin and Astra Blue. We found that this specie has vascular bundles of different sizes, organized throughout the mesophyll. Epidermal structures like trichomes, possibly protection agents and the sinuosity of their cells were identified as an auxiliary mechanical adaptation of the water flow.A Brachiaria é o gênero de pastagem mais cultivado no território brasileiro, sendo usado de diversas formas na criação de animais e de maneira bem eficiente. Sua importância econômica e ecológica motivou o presente estudo que teve como objetivo descrever a morfoanatomia foliar da Brachiaria decumbens Stapf. Para tal foram feitos cortes transversais e paradérmicos na região mediana da lâmina foliar, sendo os mesmos, submetidos à descoloração em hipoclorito de sódio comercial e corados com Safranina e Azul de Astra. Verificou-se que a espécie em questão apresenta feixes vasculares de diferentes calibres, organizados por todo o mesofilo. Apêndices epidérmicos como tricomas, possivelmente agentes de proteção, e a sinuosidade das células epidérmicas foram identificados como auxiliares da adaptação mecânica a entrada e saída de água.Brachiaria es el género de pasto más cultivado en el territorio brasileño, siendo usado de diversas formas y de manera muy eficiente en la cría de animals. Su importancia económica y ecológica motivó el presente estudio que tuvo como objetivo describir la morfoanatomía foliar de Brachiaria decumbens Stapf. Para esto se hicieron cortes transversales y paradérmicos en la región mediana de la lámina foliar, siendo los mismos sometidos a decoloración en hipoclorito de sodio comercial y coloreados con Safranina y Azul de Astra. Se verificó que la espécie presenta haces vasculares de diferentes tamaños, organizados a través del mesofilo, apéndices epidérmicos como tricomas, posiblemente agentes de protección y sinuosidad de células epidérmicas se identificaron como auxiliares de la adaptación mecánica a la entrada y salida de agua

Microbiological evaluation of sweet pies marketed fairs in special city Goiânia-GO

Submitted by Franciele Moreira ([email protected]) on 2017-09-12T19:55:04Z No. of bitstreams: 2 Artigo - Edmar Soares Nicolau - 2014.pdf: 320641 bytes, checksum: 0e687cfb1db8d6a8004c1456f763bfab (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Rejected by Claudia Moura ([email protected]), reason: on 2017-09-12T20:14:28Z (GMT)Submitted by Franciele Moreira ([email protected]) on 2017-09-12T20:15:16Z No. of bitstreams: 2 Artigo - Edmar Soares Nicolau - 2014.pdf: 320641 bytes, checksum: 0e687cfb1db8d6a8004c1456f763bfab (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira ([email protected]) on 2017-09-13T18:28:38Z (GMT) No. of bitstreams: 2 Artigo - Edmar Soares Nicolau - 2014.pdf: 320641 bytes, checksum: 0e687cfb1db8d6a8004c1456f763bfab (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Approved for entry into archive by Luciana Ferreira ([email protected]) on 2017-09-13T18:29:11Z (GMT) No. of bitstreams: 2 Artigo - Edmar Soares Nicolau - 2014.pdf: 320641 bytes, checksum: 0e687cfb1db8d6a8004c1456f763bfab (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5)Made available in DSpace on 2017-09-13T18:29:25Z (GMT). No. of bitstreams: 2 Artigo - Edmar Soares Nicolau - 2014.pdf: 320641 bytes, checksum: 0e687cfb1db8d6a8004c1456f763bfab (MD5) license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Previous issue date: 2014-02Tortas doces são alimentos largamente consumidos nas feiras especiais da cidade de Goiânia – GO. Em geral são comercializadas de forma inadequada, sem refrigeração e muitas vezes sem proteção contra os vários tipos de contaminantes, inclusive contaminação microbiana, que pode causar toxiinfecções alimentares aos consumidores. O presente trabalho teve como objetivo avaliar a qualidade microbiológica de tortas doces comercializadas em 105 bancas nas 23 feiras especiais da cidade de Goiânia, e também o impacto da capacitação dos feirantes em Boas Práticas de Fabricação (BPF) na qualidade destes produtos. Os micro-organismos investigados foram aqueles exigidos pelo padrão microbiológico vigente: Salmonella sp, coliformes termotolerantes, Bacillus cereus e Estafilococos coagulase positiva. A temperatura de exposição destes alimentos nas bancas também foi verificada. Um total de 259 amostras foi analisado, 209 na primeira etapa, antes da capacitação dos feirantes, e 50 na segunda, após qualificação dos feirantes em BPF. Das tortas doces recolhidas antes do treinamento dos feirantes, 65,6%; 20,6% e 16,8% foram consideradas impróprias para o consumo por conter coliformes termotolerantes, Estafilococos coagulase positiva e Bacillus cereus acima do limite preconizado, respectivamente. Nas amostras recolhidas após o treinamento, observou-se uma melhora nas percentagens de contaminação encontradas (28,0% continham coliformes termotolerantes, 14,0% contagem de Estafilococos coagulase positiva, e 28,0% contagem de Bacillus cereus, todos acima do limite estabelecido). Nenhuma amostra apresentou Salmonella sp em ambas as etapas. Pode-se concluir que com o treinamento dos feirantes houve uma melhora na qualidade microbiológica destes produtos. Estes resultados reforçam a necessidade de treinamento dos feirantes e o impacto que pode ter na qualidade dos produtos. As temperaturas de conservação das tortas variaram de –5,3ºC a 28,7ºC na 1ª etapa e de –3,6ºC a 24,0ºC na segunda. A presença do balcão refrigerado não foi suficiente para manter a temperatura ideal (até 10°C) para a conservação das tortas doces.The sweet pies are widely consumed in special fairs in Goiânia-GO city. In general they are marketed in inadequate way, without refrigeration and most of times without any protection against various types of contaminants, including microbial contamination that can cause food toxi-infections to consumers. This study aimed to evaluate the microbiological quality of pies sold in 105 stalls in 23 special fair city of Goiânia, and also the impact of training on the Good Manufacturing Practices (GMP) in the quality of these products. The micro-organisms investigated were those required the by standard microbiological: Salmonella, fecal coliforms, Bacillus cereus and Staphylococcus coagulase positive. We also observed the temperature exposure of these foods on newsstands. We analyzed 259 samples in total, with 209 in the first stage, before the training of the fairground, and 50 in the second, after qualifying for the fair dealers in GMP. Pies sweets collected before training of fair dealers were considered unfit for consumption because it contains health indicators above the recommended limit (65.6% with fecal coliforms, 20.6% Staphylococcus coagulase positive and 16.8% with Bacillus cereus). In samples collected after training there was an improvement in the indices (28,0% contained coliforms, 14,0% Staphylococcus coagulase positive and 28,0% of Bacillus cereus, all above the limit set). None samples had Salmonella in both steps. It can be concluded that with the training of fair dealers there was an improvement in the microbiological quality of these products. These results reinforce the need for training of the fairground and the impact it can have on the quality of the products. The storage temperatures pies ranged from –5.3ºC to 28.7ºC in first step and –3.6ºC to 24.0ºC in the second. The presence of the refrigerated was not sufficient to maintain the optimal temperature (to 10 ° C) for storage of pies

Additional file 1: Figure S1. of Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors

LINE-1 methylation pyrograms of representative samples. (A) Normal kidney; (B) Wilms tumor. Five CpG sites were evaluated in the LINE-1 promoter sequence. Arrows indicate internal controls for bisulfite conversion. (TIFF 416 kb

Additional file 2: Table S1. of Association between long interspersed nuclear element-1 methylation levels and relapse in Wilms tumors

Updated clinical data and methylation mean of the 5 LINE-1 sites of each patient. (DOCX 33 kb