1,490 research outputs found

    William Remshart: A Biographical Sketch

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    William Remshart (b. February 7, 1805, d. February 24, 1878) was a merchant who later became involved with real estate. He had the residences of 102-112 West Jones Street (also called Remshart Row) built. He was active in business and community affairs. William Remshart was first married to Julia E. Cooper on January 17, 1833 and they had nine children. After the death of Julia, William married Hrs. Rebecca C. Oliver on July 18, 1866. He died February 24, 1878 and was buried in Laurel Grove Cemetery, Savannah, Georgia.https://digitalcommons.georgiasouthern.edu/sav-bios-lane/1148/thumbnail.jp

    New reactions of oxetanes

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    This thesis describes the synthesis and new reactions of oxetan-3-ones. Chapter 1 gives an introduction to oxetanes and includes discussion of methods for their synthesis, their reactions, specifically those involving the use of oxetan-3-ones, and their relevance in medicinal chemistry and natural products. Chapter 2 begins with an introduction to multi-component reactions (MCRs) and moves on to describe our efforts in incorporating oxetanes into structurally diverse compounds using Passerini three-component reactions (P-3CRs) and Ugi four-component reactions (U-4CRs). A range of 3,3-disubstituted oxetanes are successfully made in 23-98% yield by reaction of oxetan-3-ones with various carboxylic acids and isocyanides. The synthesis of chiral 2-substituted oxetan-3- ones using the SAMP chiral auxiliary method is also demonstrated, specifically oxetan-3-one is converted into 2-benzyloxetan-3-one in 51% overall yield and 74% ee in three steps. Chapter 3 details our efforts towards the incorporation of the oxetane unit into tetrahydro-β-carbolines using the Pictet-Spengler reaction. Several oxetan-3-ones are demonstrated to take part in Pictet-Spengler reactions with tryptamine and tryptophan ethyl ester derivatives. The chemistry is successfully extended in azetidinones

    Unitary Chern-Simons matrix model and the Villain lattice action

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    We use the Villain approximation to show that the Gross-Witten model, in the weak- and strong-coupling limits, is related to the unitary matrix model that describes U(N) Chern-Simons theory on S^3. The weak-coupling limit corresponds to the q->1 limit of the Chern-Simons theory while the strong-coupling regime is related to the q->0 limit. In the latter case, there is a logarithmic relationship between the respective coupling constants. We also show how the Chern-Simons matrix model arises by considering two-dimensional Yang-Mills theory with the Villain action. This leads to a U(1)^N theory which is the Abelianization of 2d Yang-Mills theory with the heat-kernel lattice action. In addition, we show that the character expansion of the Villain lattice action gives the q deformation of the heat kernel as it appears in q-deformed 2d Yang-Mills theory. We also study the relationship between the unitary and Hermitian Chern-Simons matrix models and the rotation of the integration contour in the corresponding integrals.Comment: 17 pages, Minor corrections to match the published versio

    Non-simply-laced Lie algebras via F theory strings

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    In order to describe the appearance in F theory of the non--simply--laced Lie algebras, we use the representation of symmetry enhancements by means of string junctions. After an introduction to the techniques used to describe symmetry enhancement, that is algebraic geometry, BPS states analysis and string junctions, we concentrate on the latter. We give an explicit description of the folding of D_{2n} to B_n of the folding of E_6 to F_4 and that of D_4 to G_2 in terms of junctions and Jordan strings. We also discuss the case of C_n, but we are unable in this case to provide a string interpretation.Comment: 24 pages, 3 figure

    Scavenger community response to the removal of a dominant scavenger

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    The alteration of scavenging communities can reduce basic ecosystem services and increase risks to human and wildlife health. Recent work demonstrated that scavenging communities in agricultural landscapes are extremely efficient: superabundant mesopredators sequestered system energy by dominating scavenging activity. To explore how the disturbance of these communities affects the stability of carrion removal as an ecosystem function, we experimentally manipulated a scavenging community within an agricultural landscape by reducing the abundance of the dominant scavenger, raccoons Procyon lotor. We then monitored the fates of 676 mouse Mus musculus carcasses placed in 13 control and 13 removal woodlots from June 2007 – May 2008. The diversity of vertebrate scavengers did not change between control and removal woodlots and scavenging by invertebrates was unaffected by our experiment. Although Virginia opossums Didelphis virginiana and other scavengers exhibited a functional response when raccoons were reduced in abundance, the increases did not change the proportional allocation of carcasses among scavengers. Finally, the reduced abundance of a major scavenger affected system efficiency. More carcasses remained un-scavenged at the end of trials in removal woodlots than in control woodlots. This experiment demonstrates the vulnerability of a critical ecosystem service, carrion removal, to perturbations of the scavenging community and serves to highlight the method by which scavenger communities may respond to perturbations

    Mixed-method approaches to strengthen economic evaluations in implementation research

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    Abstract Background Guidance from economic evaluations on which implementation strategies represent the best return on investment will be critical to advancing the Triple Aim of health care: improving patient care and population health while minimizing per-capita cost. The results of traditional (quantitative) economic evaluations are limited by a remaining “qualitative residual” of contextual information and stakeholders perspectives, which cannot be captured by monetary values alone and is particularly prevalent in implementation science research. The emergence of qualitative methods for economic evaluation offers a promising solution. Main body To maximize the contributions of economic evaluations to implementation science, we recommend that researchers embrace a mixed-methods research agenda that merges traditional quantitative approaches with innovative, contextually grounded qualitative methods. Such studies are exceedingly rare at present. To assist implementation scientists in making use of mixed methods in this research context, we present an adapted taxonomy of mixed-method studies relevant to economic evaluation. We then illustrate the application of mixed methods in a recently completed cost-effectiveness evaluation, making use of an adapted version of reporting standards for economic evaluations. Conclusions By incorporating qualitative methods, implementation researchers can enrich their economic evaluations with detailed, context-specific information that tells the full story of the costs and impacts of implementation. We end by providing suggestions for building a research agenda in mixed-method economic evaluation, along with more resources and training to support investigators who wish to answer our call to action.https://deepblue.lib.umich.edu/bitstream/2027.42/146781/1/13012_2018_Article_850.pd

    The use of ion mobility spectrometry and gas chromatography/mass spectrometry for the detection of illicit drugs on clandestine records

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    Illicit drug distribution has over the past decade grown tremendously from simple 'drug pushing' where drugs were distributed from poorly organized individuals to today's well organized and well financed drug cartels. This change to a more 'corporate-like' atmosphere has resulted in a greater use of record keeping to monitor the profits generated. The use of record keeping by drug distributors is not restricted to high level drug smugglers but is used at all levels within the distribution network. Dealers at all levels including street dealers are generally 'fronted', given on consignment quantities of drugs that they in turn sell to customers, thereby requiring the need for records to keep track of drug sales versus liabilities. These records because of their illicit nature are often encrypted to hide the fact that they are indeed records of drug transactions. The creation of a handwritten notation concerning a drug transaction is normally brought on because of a purchase or sale. In a sale, this is commonly accomplished through a consignment, or the designation of a quantity to a customer to whom that amount has been 'fronted'. Because this activity generates a debt, it follows that an accounting for payments made, as well as new transactions completed, is only logical. One of the most common means of representing these is through an 'accounting flow', in which payments are subtracted from a running balance while new sales are added to it. The examination of illicit drug records has been the key to the prosecution of numerous federal, state, and local drug cases for a number of years. The Document Section of the FBI Laboratory, through its Racketeering Records Analysis Unit (RRAU), has been involved in such analytical efforts since 1983. Detailed analytical research brought about an evolution in the systematic approach utilized in the RRAU since that time. The close proximity of the drugs to the records often results in trace drug evidence being transferred to the records. The detection of trace drug residue on surfaces by ion mobility spectrometry (IMS) is well documented in literature. The following procedure will deal primarily with the newer techniques of trace drug analysis and drug record analysis developed by the Chemistry/Toxicology Unit of the FBI Laboratory since the more traditional techniques of latent finger print analysis and document analysis are well known

    Supersymmetric States in M5/M2 CFTs

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    We propose an exact, finite NN formula for the partition function over 1/4th1/4^{th} BPS states in the conformal field theory on the world volume of NN coincident M5 branes and 1/8th1/8^{th} BPS states in the theory of NN coincident M2 branes. We obtain our partition function by performing the radial quantization of the Coulomb Branches of these theories, and rederive the same formula from the quantization of supersymmetric giant and dual giant gravitons in AdS7Ă—S4AdS_7 \times S^4 and AdS4Ă—S7AdS_4 \times S^7. Our partition function is qualitatively similar to the analogous quantity in N=4{\cal N}=4 Yang Mills. It reduces to the sum over supersymmetric multi gravitons at low energies, but deviates from this supergravity formula at energies that scale like a positive power of NN.Comment: 24 pages, harvmac; v2 reference adde
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