Deuteron and proton beams polarimetry at internal target at JINR Nuclotron

The spin program at SPD NICA as well as the experiments at Nuclotron require high intensity polarized proton and deuteron beams with high value of the polarization. The upgraded deuteron beam polarimeter at internal target at Nuclotron has been used to obtain the vector and tensor polarization for 6 different spin modes of new polarized source of ions. The values of the beam polarization was about 65-75% from their ideal values. The longterm stability of the deuteron beam polarization was demonstrate

Simulation of Be armour cracking under ITER-like transient heat loads

Simulation of beryllium cracking under action of multiple severe surface heatings has been performed using the PEGASUS-3D code and verified by experiments in the JUDITH 1 facility. Analysis of the results has revealed beryllium thermo conductivity degradation under action of repetitive pulsed heat load due to accumulation of the cracks in the surface layer. Thermo conductivity degradation is found to be at least 4 times after 100 pulses in JUDITH 1 facility. An analytical model for the Be cracking threshold under action of arbitrary heat pulses has been developed

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline

Small non-coding piRNAs act as sequence-specific guides to repress complementary targets in Metazoa. Prior studies in Drosophila ovaries have demonstrated the function of piRNA pathway in transposon silencing and therefore genome defense. However, the ability of piRNA program to respond to different transposon landscape and the role of piRNAs in regulating host gene expression remain poorly understood. Here, we comprehensively analyzed piRNA expression and defined the repertoire of their targets in Drosophila melanogaster testes. Comparison of piRNA programs between sexes revealed sexual dimorphism in piRNA programs that parallel sex-specific transposon expression. Using a novel bioinformatic pipeline, we identified new piRNA clusters and established complex satellites as dual-strand piRNA clusters. While sharing most piRNA clusters, two sexes employ them differentially to combat sex-specific transposon landscape. We found several host genes targeted by piRNAs in testis, including CG12717/pita, a SUMO protease gene. piRNAs encoded on Y chromosome silence pita, but not its paralog, to exert sex- and paralog-specific gene regulation. Interestingly, pita is targeted by endogenous siRNAs in a sibling species, Drosophila mauritiana, suggesting distinct but related silencing strategies invented in recent evolution to regulate a conserved protein-encoding gene

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in D. melanogaster male germline

Small noncoding piRNAs act as sequence-specific guides to repress complementary targets in Metazoa. Prior studies in Drosophila ovaries have demonstrated the function of the piRNA pathway in transposon silencing and therefore genome defense. However, the ability of the piRNA program to respond to different transposon landscapes and the role of piRNAs in regulating host gene expression remain poorly understood. Here, we comprehensively analyzed piRNA expression and defined the repertoire of their targets in Drosophila melanogaster testes. Comparison of piRNA programs between sexes revealed sexual dimorphism in piRNA programs that parallel sex-specific transposon expression. Using a novel bioinformatic pipeline, we identified new piRNA clusters and established complex satellites as dual-strand piRNA clusters. While sharing most piRNA clusters, the two sexes employ them differentially to combat the sex-specific transposon landscape. We found two piRNA clusters that produce piRNAs antisense to four host genes in testis, including CG12717/pirate, a SUMO protease gene. piRNAs encoded on the Y chromosome silence pirate, but not its paralog, to exert sex- and paralog-specific gene regulation. Interestingly, pirate is targeted by endogenous siRNAs in a sibling species, Drosophila mauritiana, suggesting distinct but related silencing strategies invented in recent evolution to regulate a conserved protein-coding gene

An analysis of electron distributions in galaxy clusters by means of the flux ratio of iron lines FeXXV and XXVI

The interpretation of hard X-ray emission from galaxy clusters is still ambiguous and different models proposed can be probed using various observational methods. Here we explore a new method based on Fe line observations. Spectral line emissivities have usually been calculated for a Maxwellian electron distribution. In this paper a generalized approach to calculate the iron line flux for a modified Maxwellian distribution is considered. We have calculated the flux ratio of iron lines for the various possible populations of electrons that have been proposed to account for measurements of hard X-ray excess emission from the clusters A2199 and Coma. We found that the influence of the suprathermal electron population on the flux ratio is more prominent in low temperature clusters (as Abell 2199) than in high temperature clusters (as Coma).Comment: 6 pages, 3 figures, accepted for publication in A&