Interpretation of aeromagnetic data using GIS to evaluate the geotectonic regime of the Sabinas Basin

The study present the use of Geographic Information System (GIS) to assess the geotectonic regimen of the Sabinas Basin. Initially, the GIS database was designed using geological and geophysical information (total magnetic field reduced to the pole). Subsequently, 2D models of the basin were obtained along 4 profiles running on a north-south direction. The implementation of GIS enables a geological-geophysical interpretation generating various thematic maps that overlap the magnetic map during interpretation. The analysis of overlapping maps enables the identification of areas with different geotectonic regimes in the Sabinas Basin, as well as the relationship between these environments and mineralization. The qualitative and quantitative interpretation of the aeromagnetic data obtained for the total magnetic field reduced to the pole delineate uplifted basement areas as well as shallower blocks within them. This paper presents the location of both the basin´s deepest zones and its probable faults, which can be linked to the block boundaries. The faults zones and block boundaries correspond to the main mineral deposits found in the basin. Finally, the geotectonic regime of some sectors of the basin is detailed in order to reaffirm the results obtained by the interpretation of aeromagnetic data.Se presenta el uso de un Sistemas de Información Geográfica para evaluar el régimen geotectónico de la Cuenca de Sabinas. Inicialmente se llevó a cabo el diseño de la base de datos del Sistema de Información Geográfica, teniendo en cuenta las características de la información geológica y geofísica (campo magnético total reducido al polo). Posteriormente se obtienen modelos 2D de la cuenca a lo largo de 4 perfiles con direcciones norte-sur. A partir de la implementación del Sistema de Información Geográfica, se logró una interpretación geológica-geofísica, generando diversos mapas temáticos que se superpusieron al mapa magnético durante dicha interpretación. El análisis de los mapas superpuestos permitió identificar áreas con diferente régimen geotectónico dentro de la Cuenca de Sabinas, así como la relación de esas áreas con mineralizaciones. A partir de la interpretación cualitativa y cuantitativa de los datos del campo magnético total reducido al polo se delimitan áreas levantadas del basamento de la cuenca y los bloques más someros dentro de las mismas. También se localizan las zonas más profundas de la cuenca y probables fallas, que pueden estar vinculadas con los límites de los bloques. Las zonas de fallas y los límites de bloques están relacionados con los principales depósitos minerales de la cuenca. Por último, se detalla el régimen geotectónico de algunos sectores de la cuenca, para reafirmar los resultados de la interpretación de los datos aeromagnéticos

Immediate feedback in computerized environments through videos in mathematics discipline

No contexto escolar, a avaliação permeia todo o processo ensino-aprendizagem. Entretanto, muitas vezes a avaliação tem simplesmente o caráter comparativo e classificatório, sem atender às necessidades individuais dos alunos e sem oferecer o devido retorno. Assim, o feedback adequado pode ser um retorno que conscientiza os alunos sobre suas habilidades, suas competências, seus conhecimentos e como os mesmos são obtidos. Este trabalho discute e apresenta os resultados de um experimento pedagógico, realizado no Ensino Médio de uma escola pública, em que é desenvolvido retorno imediato através de vídeo-feedback de atividades desenvolvidas no âmbito da disciplina de matemática, disponibilizado em ambiente informatizado. O objetivo deste vídeo-feedback é promover, de forma personalizada, melhoria do desempenho de cada aluno. Os resultados obtidos através do experimento mostraram, com base em método estatístico, evidências suficientes que indicam uma melhoria no desempenho dos alunos em matemática que utilizaram os vídeos-feedback durante a atividade de avaliação.In the school context, evaluation permeates the entire teaching-learning process. However, the evaluation is often simply comparative and classificatory, without attending to the individual needs of the students and without offering the necessary return. Thus, appropriate feedback can be a return that provides important information about students' competencies, what they know, what they do, and how they do it. This work discusses and presents the results of a pedagogic experiment, carried out in the High School of a public school, in which an immediate feedback process is developed in the mathematics discipline, made available in a computerized environment, through videos-feedback, whose objective is to promote in a performance of students. The research showed, through statistical test, sufficient evidence that indicated the promotion of student performance in mathematics, after the use of videos-feedback, inserted in evaluation in computerized environment

The homework in the math discipline mediated by virtual assistant-Chatbot

A tarefa de casa, prática há muito realizada nas escolas, apresenta como uma das dificuldades a falta de apoio e auxílio para a sua realização fora da escola. Este trabalho discute e apresenta os resultados de um experimento pedagógico, utilizando um assistente virtual (Chatbot), realizada na disciplina de matemática em uma escola pública, cujo objetivo foi analisar a utilização desse assistente na realização da tarefa de casa, considerando a participação e o rendimento dos estudantes. O Chatbot foi construído a fim de possibilitar interação acessível com os alunos, mediando a realização da tarefa de casa. Os resultados parciais deste experimento indicam uma boa aceitação dos alunos em relação à utilização dessa assistente virtual como auxílio na realização da tarefa de casa.The homework, long practiced in schools, presents as one of the difficulties the lack of support and assistance for its achievement outside school. This work discusses and presents the results of a pedagogical experiment using a virtual assistant (Chatbot), carried out in the mathematics discipline in a public school, whose objective was to analyze the use of this assistant in the accomplishment of the homework, considering the participation and the students' income. The Chatbot was built in order to enable accessible interaction with the students, mediating the accomplishment of the homework assignment. The partial results of this experiment indicate a good acceptance of the students regarding the use of this virtual assistant as an aid in the accomplishment of the homework

Skeletal muscle structure and function in response to electrical stimulation in moderately impaired COPD patients

Study objective: To determine the structural and functional consequences of high-frequency neuromuscular electrical stimulation (hf-NMES) in a group of moderately impaired outpatients with chronic obstructive pulmonary disease (COPD).Design: A prospective, cross-over randomized trial.Setting: An university-based, tertiary center.Patients and materials: Seventeen patients (FEV1 = 49.6 +/- 13.4% predicted, Medical Research Council dyspnoea grades II-III) underwent 6-weeks hf-NMES (50 Hz) and sham stimulation of the quadriceps femoris in a randomized, cross-over design. Knee strength was measured by isokinetic dynamometry (peak torque) and leg muscle mass (LMM) by DEXA; in addition, median cross-sectional area (CSA) of type I and fibres and capillary-fibre ratio were evaluated in the vastus lateralis. the 6-min walking distance (6MWD) was also determined.Universidade Federal de São Paulo, UNIFESP, Pulm Funct & Clin Exercise Physiol Unit, SEFIC,Div Resp Dis,Dept Med, São Paulo, BrazilUniversidade Federal de São Paulo, UNIFESP, Neuromusc Div, São Paulo, BrazilUniv Glasgow, Inst Biomed & Life Sci, Glasgow, Lanark, ScotlandUniversidade Federal de São Paulo, UNIFESP, Pulm Funct & Clin Exercise Physiol Unit, SEFIC,Div Resp Dis,Dept Med, São Paulo, BrazilUniversidade Federal de São Paulo, UNIFESP, Neuromusc Div, São Paulo, BrazilWeb of Scienc

Application of the Peer Instruction method in the teaching of computer algorithms and programming

O presente trabalho discute e apresenta os resultados de um experimento realizado na disciplina de algoritmos e programação de computadores de uma escola pública, utilizando o método de ensino Peer Instruction (Instrução por Pares). O objetivo foi avaliar a eficácia do método, considerando aspectos referentes ao desempenho e o engajamento de estudantes novatos e experientes em programação do curso Técnico em Informática integrado ao Ensino Médio. Análises preliminares mostram um crescimento no desempenho dos alunos e indicam que aqueles em iniciação na programação têm uma pré-disposição em trabalhar de modo colaborativo comparado aos alunos com mais experiência.The present work discusses and presents the results of an experiment applied in the discipline of computer algorithms and programming of a public school, using the method of teaching Peer Instruction. The objective was to evaluate the effectiveness of the method, considering aspects related to the performance and the engagement of novice and experienced students in programming of the Technical Course in Information Technology integrated to High School. Preliminary analyzes show a growth in student performance and indicate that those in early programming have a disposition to work collaboratively compared to more experienced students

In vitro effects of European and Latin-American medicinal plants in CYP3A4 gene expression, glutathione levels, and P-glycoprotein activity

Many medicinal plants species from European -such as Artemisia absinthium, Equisetum arvense, Lamium album, Malva sylvestris, Morus nigra, Passiflora incarnata, Frangula purshiana, and Salix alba- as well as Latin American traditions -such as Libidibia ferrea, Bidens pilosa, Casearia sylvestris, Costus spicatus, Monteverdia ilicifolia, Persea americana, Schinus terebinthifolia, Solidago chilensis, Syzygium cumini, Handroanthus impetiginosus, and Vernonanthura phosphorica- are shortlisted by the Brazilian National Health System for future clinical use. However, they lack many data on their action upon some key ADME targets. In this study, we assess non-toxic concentrations (up to100 μg/ml) of their infusions for in vitro ability to modulate CYP3A4 mRNA gene expression and intracellular glutathione levels in HepG2 cells, as well as P-glycoprotein (P-gp) activity in vincristine-resistant Caco-2 cells (Caco-2 VCR). We further investigated the activation of human pregnane X receptor (hPXR) in transiently co-transfected HeLa cells and the inhibition of Gamma-glutamyl transferase (GGT) in HepG2 cells. Our results demonstrate L. ferrea, C. sylvestris, M. ilicifolia, P. americana, S. terebinthifolia, S. cumini, V. phosphorica, E. arvense, P. incarnata, F. purshiana, and S. alba can significantly increase CYP3A4 mRNA gene expression in HepG2 cells. Only F. purshiana shown to do so likely via hPXR activation. P-gp activity was affected by L. ferrea, F. purshiana, S. terebinthifolia, and S. cumini. Total intracellular glutathione levels were significantly depleted by exposure to all extracts except S. alba and S. cumini This was accompanied by a lower GGT activity in the case of C. spicatus, P. americana, S. alba, and S. terebinthifolia, whilst L. ferrea, P. incarnata and F. purshiana increased it. Surprisingly, S. cumini aqueous extract drastically decreased GGT activity (−48%, p < 0.01). In conclusion, this preclinical study shows that the administration of some of these herbal medicines causes in vitro disturbances to key drug metabolism mechanisms. We recommend active pharmacovigilance for Libidibia ferrea (Mart.) L. P. Queiroz, Frangula purshiana Cooper, Schinus terebinthifolia Raddi, and Salix alba L. which were able to alter all targets in our preclinical study

Energy Estimation of Cosmic Rays with the Engineering Radio Array of the Pierre Auger Observatory

The Auger Engineering Radio Array (AERA) is part of the Pierre Auger Observatory and is used to detect the radio emission of cosmic-ray air showers. These observations are compared to the data of the surface detector stations of the Observatory, which provide well-calibrated information on the cosmic-ray energies and arrival directions. The response of the radio stations in the 30 to 80 MHz regime has been thoroughly calibrated to enable the reconstruction of the incoming electric field. For the latter, the energy deposit per area is determined from the radio pulses at each observer position and is interpolated using a two-dimensional function that takes into account signal asymmetries due to interference between the geomagnetic and charge-excess emission components. The spatial integral over the signal distribution gives a direct measurement of the energy transferred from the primary cosmic ray into radio emission in the AERA frequency range. We measure 15.8 MeV of radiation energy for a 1 EeV air shower arriving perpendicularly to the geomagnetic field. This radiation energy -- corrected for geometrical effects -- is used as a cosmic-ray energy estimator. Performing an absolute energy calibration against the surface-detector information, we observe that this radio-energy estimator scales quadratically with the cosmic-ray energy as expected for coherent emission. We find an energy resolution of the radio reconstruction of 22% for the data set and 17% for a high-quality subset containing only events with at least five radio stations with signal.Comment: Replaced with published version. Added journal reference and DO

Measurement of the Radiation Energy in the Radio Signal of Extensive Air Showers as a Universal Estimator of Cosmic-Ray Energy

We measure the energy emitted by extensive air showers in the form of radio emission in the frequency range from 30 to 80 MHz. Exploiting the accurate energy scale of the Pierre Auger Observatory, we obtain a radiation energy of 15.8 \pm 0.7 (stat) \pm 6.7 (sys) MeV for cosmic rays with an energy of 1 EeV arriving perpendicularly to a geomagnetic field of 0.24 G, scaling quadratically with the cosmic-ray energy. A comparison with predictions from state-of-the-art first-principle calculations shows agreement with our measurement. The radiation energy provides direct access to the calorimetric energy in the electromagnetic cascade of extensive air showers. Comparison with our result thus allows the direct calibration of any cosmic-ray radio detector against the well-established energy scale of the Pierre Auger Observatory.Comment: Replaced with published version. Added journal reference and DOI. Supplemental material in the ancillary file