Revisiting the Ambivalent Sexism Inventory’s adolescent and brief versions: problems, solutions, and considerations

The Ambivalent Sexism Inventory (ASI) has been widely used in applied research and sometimes modified versions have been proposed. The current research aimed to test the factor validity and reliability of the ASI for adolescents (ASI-A) and Brief ASI (B-ASI) versions in the adolescent population. Two analogue samples of Mexican secondary students (Study 1: n1 = 975; Study 2: n2 = 1020) composed the sample. The ASI-A showed that the two-dimension model omitting items 1 to 4 is the most recommendable model and it presents an acceptable fitting to the data (Study 1). The B-ASI bidimensional model showed an appropriate fitting to the data and no modifications were required (Study 2). The ASI-A is a valid measure of ambivalent sexism when some of its items are omitted, but the demonstrated validity of the original items in the adolescent population supports that there was no theoretical or empirical reason for developing a specific version for adolescents of the ASI. El inventario de sexismo ambivalente (ASI) es frecuentemente utilizado en la investigación aplicada, lo que ha llevado a que en ocasiones se propongan versiones modificadas del mismo. La presente investigación tuvo por objetivo evaluar la validez factorial y la fiabilidad de la versión para adolescentes (ASI-A) y la versión breve (B-ASI) de este inventario en población adolescente. Se utilizaron los datos de dos muestras análogas de estudiantes de secundaria de México (estudio 1: n1 = 975; estudio 2: n2 = 1020). El modelo de dos dimensiones omitiendo los ítems 1 a 4 resultó ser el más recomendable en el caso del ASI-A presentando un ajuste aceptable (estudio 1). El modelo bidimensional también result ser el más apropiado en el caso del B-ASI al obtener un ajuste adecuado a los datos sin requerir ninguna modificación (estudio 2). El ASI-A es un instrumento de medida válido cuando algunos de los ítems son omitidos, pero la demostrada validez de la versión original de la escala incluso en población adolescente cuestiona la pertinencia teórica y empírica para desarrollar una versión específica para adolescentes

Furanosic forms of sugars: conformational equilibrium of methyl beta-D-ribofuranoside

The investigation of an isolated ribofuranose unit in the gas phase reveals the intrinsic conformational landscape of the biologically active sugar form.We report the rotational spectra of two conformers of methyl b-D-ribofuranoside in a supersonic jet expansion. Both conformers adopt a near twisted (3T2) ring conformation with the methoxy and hydroxymethyl substituents involved in various intramolecular hydrogen bonds.MINECO-FEDER CTQ2015-68148-C2-

Exploring the Influence of Intermolecular Interactions in Prebiotic Chemistry Using Laser Spectroscopy and Calculations

One of the most fascinating questions in chemistry is why nature chose CGAT as the alphabet of life. Very likely, such selection was the result of multiple factors and a long period of refinement. Here, we explore how the intermolecular interactions influenced such process, by characterizing the formation of dimers between adenine, theobromine and 4-aminopyrimidine. Using a combination of mass-resolved excitation spectroscopy and DFT calculations, we determined the structure of adenine-theobromine and 4-aminopyrimidine-theobromine dimers. The binding energy of these dimers is very close to the canonical adenine-thymine nucleobases. Likewise, the dimers are able to adopt Watson-Crick conformations. These findings seem to indicate that there were many options available to build the first versions of the informational polymers, which also had to compete with other molecules, such as 4-aminopyrimidine, which does not have a valid attaching point for a saccharide. For some reason, nature did not select the most strongly-bonded partners or if it did, such proto-bases were later replaced by the nowadays canonical CGAT.We thank MICIU (PGC2018-098561-B-C21) and the Basque Government (IT1162-19) for financial support. A.C. thank the Basque Government for a pre-doctoral fellowship.Peer reviewe

Conformational Behavior of d -Lyxose in Gas and Solution Phases by Rotational and NMR Spectroscopies

International audienc

Competencia mediática: investigación sobre el grado de competencia de la ciudadanía en España

Producción CientíficaLa educación mediática no ha tenido un papel importante en los currículos escolares, en los planes de estudios universitarios, en los medios de comunicación y en la propia sociedad, a pesar de la fuerte presencia de la comunicación mediática en todos los ámbitos de nuestra vida personal y social. Este abandono de la educación mediática implica una ausencia de definiciones y de evaluaciones sobre el grado de competencia mediática de las personas. Un primer paso para la definición del concepto de competencia mediática se dio mediante el diseño del documento «Competencias en Comunicación Audiovisual», auspiciado por el CAC) y consensuado por un grupo de expertos españoles. El documento define los ámbitos de incidencia de esta competencia y las dimensiones que debe cumplir: el lenguaje, la tecnología, los procesos de producción y programación, la ideología y los valores, la recepción y las audiencias, y la dimensión estética.Departamento de Historia Moderna, Contemporánea y de América, Periodismo y Comunicación Audiovisual y Publicidad

Impact on clinical practice of the implementation of guidelines for the toxicity management of targeted therapies in kidney cancer. The protect-2 study.

Journal Article;BACKGROUND The impact of such recommendations after their implementation of guidelines has not usually been evaluated. Herein, we assessed the impact and compliance with the Spanish Oncology Genitourinary Group (SOGUG) Guidelines for toxicity management of targeted therapies in metastatic renal cell carcinoma (mRCC) in daily clinical practice. METHODS Data on 407 mRCC patients who initiated first-line targeted therapy during the year before and the year after publication and implementation of the SOGUG guideline program were available from 34 Spanish Hospitals. Adherence to SOGUG Guidelines was assessed in every cycle. RESULTS Adverse event (AE) management was consistent with the Guidelines as a whole for 28.7 % out of 966 post-implementation cycles compared with 23.1 % out of 892 pre-implementation cycles (p = 0.006). Analysis of adherence by AE in non-compliant cycles showed significant changes in appropriate management of hypertension (33 % pre-implementation vs. 44.5 % post-implementation cycles; p < 0.0001), diarrhea (74.0 % vs. 80.5 %; p = 0.011) and dyslipemia (25.0 % vs. 44.6 %; p < 0.001). CONCLUSIONS Slight but significant improvements in AE management were detected following the implementation of SOGUG recommendations. However, room for improvement in the management of AEs due to targeted agents still remains and could be the focus for further programs in this direction.This study was funded by Pfizer, S.L.U. Medical writing assistance was provided by Esther Tapia, PhD and was founded by Pfizer.Ye