Full deautonomisation by singularity confinement as an integrability test

Since its introduction, the method of full deautonomisation by singularity confinement has proved a strikingly effective way of detecting the dynamical degrees of birational mappings of the plane. This method is based on an observed link between two a priori unrelated notions: firstly the dynamical degree of the mapping and secondly the evolution of parameters required for its singularity structure to remain unchanged under a sufficiently general deautonomisation. We give a proof of this conjectured correspondence for a large class of birational mappings of the plane via the spaces of initial conditions for their deautonomised versions. We show that even for non-integrable mappings in this class, the surfaces forming these spaces have effective anticanonical divisors and one can define a kind of period map similar to that in the theory of rational surfaces associated with discrete Painlev\'e equations. This provides a bridge between the evolution of coefficients in the deautonomised mapping and the induced dynamics on the Picard lattice which encode the dynamical degree.Comment: 50 pages, 13 figure

Religiosity, depression, and quality of life in bipolar disorder: a two-year prospective study

Objective: Few quantitative studies have examined the effect of religious involvement on the course of bipolar disorder (BD). We investigated the effects of religious activity and coping behaviors on the course of depression, mania, and quality of life (QoL) in patients with BD. Methods: Two-year longitudinal study of 168 outpatients with BD. Linear regression was used to examine associations between religious predictors and outcome variables (manic symptoms, depression, QoL), controlling for sociodemographic variables. Results: Among the 158 patients reassessed after 2 years, positive religious coping at T1 predicted better QoL across all four domains: physical (β = 10.2, 95%CI 4.2 to 16.1), mental (β = 13.4, 95%CI 7.1 to 19.7), social (β = 10.5, 95%CI 3.6 to 17.33), and environmental (β = 11.1, 95%CI 6.2 to 16.1) at T2. Negative religious coping at T1 predicted worse mental (β = -28.1, 95%CI -52.06 to -4.2) and environmental (β = -20.4, 95%CI -39.3 to -1.6) QoL. Intrinsic religiosity at T1 predicted better environmental QoL (β = 9.56, 95%CI 2.76 to 16.36) at T2. Negative religious coping at T1 predicted manic symptoms (β = 4.1) at T2. Conclusion: Religiosity/spirituality (R/S) may influence the QoL of patients with BD over time, even among euthymic patients. Targeting R/S (especially positive and negative religious coping) in psychosocial interventions may enhance the quality of recovery in patients with BD.

Charmed particles production in pA-interactions at 70 GeV

The results of the SERP-E-184 experiment at the U-70 accelerator (IHEP, Protvino) are presented. Interactions of the 70 GeV proton beam with carbon, silicon and lead targets were studied to detect decays of charmed $D^0$, $\bar D^0$, $D^+$, $D^-$ mesons and $\Lambda_c^+$ baryon near their production threshold. Measurements of lifetimes and masses have shown a good agreement with PDG data. The inclusive cross sections of charm production and their A-dependencies have been obtained. The yields of these particles are compared with the theoretical predictions and the data of other experiments. The measured cross section of the total open charm production $\sigma(c\bar c) = 7.1 \pm 2.3(stat) \pm 1.4(syst)$ $\mu$b/nucleon at the collision c.m. energy $\surd s$ = 11.8 GeV is well above the QCD model predictions. The contributions of different kinds of charmed particles to the total cross section of the open charm production in proton-nucleus interactions vary with energy.Comment: Presented at 19th International Seminar on High Energy Physics QUARKS-2016 (Pushkin, Russia, 29 May - 4 June, 2016.). 11 pages, 9 figure

Multiplicity Studies and Effective Energy in ALICE at the LHC

In this work we explore the possibility to perform ``effective energy'' studies in very high energy collisions at the CERN Large Hadron Collider (LHC). In particular, we focus on the possibility to measure in $pp$ collisions the average charged multiplicity as a function of the effective energy with the ALICE experiment, using its capability to measure the energy of the leading baryons with the Zero Degree Calorimeters. Analyses of this kind have been done at lower centre--of--mass energies and have shown that, once the appropriate kinematic variables are chosen, particle production is characterized by universal properties: no matter the nature of the interacting particles, the final states have identical features. Assuming that this universality picture can be extended to {\it ion--ion} collisions, as suggested by recent results from RHIC experiments, a novel approach based on the scaling hypothesis for limiting fragmentation has been used to derive the expected charged event multiplicity in $AA$ interactions at LHC. This leads to scenarios where the multiplicity is significantly lower compared to most of the predictions from the models currently used to describe high energy $AA$ collisions. A mean charged multiplicity of about 1000-2000 per rapidity unit (at $\eta \sim 0$) is expected for the most central $Pb-Pb$ collisions at $\sqrt{s_{NN}} = 5.5 TeV$.Comment: 12 pages, 19 figures. In memory of A. Smirnitski

SOCS3 Expression by Thymic Stromal Cells Is Required for Normal T Cell Development

The suppressor of cytokine signaling 3 (SOCS3) is a major regulator of immune responses and inflammation as it negatively regulates cytokine signaling. Here, the role of SOCS3 in thymic T cell formation was studied in Socs3fl/fl Actin-creER mice (Δsocs3) with a tamoxifen inducible and ubiquitous Socs3 deficiency. Δsocs3 thymi showed a 90% loss of cellularity and altered cortico-medullary organization. Thymocyte differentiation and proliferation was impaired at the early double negative (CD4-CD8-) cell stage and apoptosis was increased during the double positive (CD4+CD8+) cell stage, resulting in the reduction of recent thymic emigrants in peripheral organs. Using bone marrow chimeras, transplanting thymic organoids and using mice deficient of SOCS3 in thymocytes we found that expression in thymic stromal cells rather than in thymocytes was critical for T cell development. We found that SOCS3 in thymic epithelial cells (TECs) binds to the E3 ubiquitin ligase TRIM 21 and that Trim21−/− mice showed increased thymic cellularity. Δsocs3 TECs showed alterations in the expression of genes involved in positive and negative selection and lympho-stromal interactions. SOCS3-dependent signal inhibition of the common gp130 subunit of the IL-6 receptor family was redundant for T cell formation. Together, SOCS3 expression in thymic stroma cells is critical for T cell development and for maintenance of thymus architecture.publishedVersio

Transient Behavior of variable speed pump-turbine units

This paper presents the modeling, simulation and analysis of the dynamic behavior of a fictitious 2x320 MW variable speed pump-turbine power plant including hydraulic system, electrical installations, rotating inertias and control systems. First, the modeling of hydraulic and electrical components of the power plant is presented. Then, the possible control strategies and the related block diagram are presented. The dynamic performances of the different control strategies are compared by the simulation of change of active power set points. Dynamic performances of the different control strategies are discussed

Hydrodynamic Isotonic Fluid Delivery Ameliorates Moderate-to-Severe Ischemia-Reperfusion Injury in Rat Kidneys

Highly aerobic organs like the kidney are innately susceptible to ischemia-reperfusion (I/R) injury, which can originate from sources including myocardial infarction, renal trauma, and transplant. Therapy is mainly supportive and depends on the cause(s) of damage. In the absence of hypervolemia, intravenous fluid delivery is frequently the first course of treatment but does not reverse established AKI. Evidence suggests that disrupting leukocyte adhesion may prevent the impairment of renal microvascular perfusion and the heightened inflammatory response that exacerbate ischemic renal injury. We investigated the therapeutic potential of hydrodynamic isotonic fluid delivery (HIFD) to the left renal vein 24 hours after inducing moderate-to-severe unilateral IRI in rats. HIFD significantly increased hydrostatic pressure within the renal vein. When conducted after established AKI, 24 hours after I/R injury, HIFD produced substantial and statistically significant decreases in serum creatinine levels compared with levels in animals given an equivalent volume of saline via peripheral infusion (P<0.05). Intravital confocal microscopy performed immediately after HIFD showed improved microvascular perfusion. Notably, HIFD also resulted in immediate enhancement of parenchymal labeling with the fluorescent dye Hoechst 33342. HIFD also associated with a significant reduction in the accumulation of renal leukocytes, including proinflammatory T cells. Additionally, HIFD significantly reduced peritubular capillary erythrocyte congestion and improved histologic scores of tubular injury 4 days after IRI. Taken together, these results indicate that HIFD performed after establishment of AKI rapidly restores microvascular perfusion and small molecule accessibility, with improvement in overall renal function

Prospectus, April 26, 1977

VOTE TODAY-TOMORROW: FOUR VIE FOR PRES. IN STU-GO ELECTION; Remus, Mayeda run for V.P.; Albert Dodson unopposed; Activities Day May 3; Letters to the editor: Pres. Praises carnival, Mayeda warns of lies, Cartoon good…but, Stu-Go made many contributions: Onley; Editorial: Trouble for athletics; Hackett vs. Slack for convo., Cox opposes Stoeber for IOC; Unopposed: Propeck runs alone for secretary; Thursday set for wheel chair awareness; State provides funding for food sanitation course; Law Enforcement Club sponsors Mk\u27t Place fair; Markland: bigger not better for Twin City police force; Energy saving tips: Ripple effect causes waste; Police Chief Dye: \u27Recruitment-lifeline of police dep\u27t.\u27; Bike race today; Blooming Idiots come out of woodwork for IOC Carnival; Workshop set for Saturday: Puppetmaster Schmidt displays at PC; Afro American Theatre Workshop starts at PC; \u27Alcohol, sophisticated, sexy?\u27; Bike tour Sunday, May 1; Classifieds; Bat girls provide needed help for baseball team; Cobras expand record with 3rd no-hitter; Lincolnland doubleheader tomorrow: Women\u27s softball season nears end; June 7-10: Mudrock headed to JC golf nationalshttps://spark.parkland.edu/prospectus_1977/1018/thumbnail.jp

Olfactory Nomenclature: An Orchestrated Effort to Clarify Terms and Definitions of Dysosmia, Anosmia, Hyposmia, Normosmia, Hyperosmia, Olfactory Intolerance, Parosmia, and Phantosmia/Olfactory Hallucination

BACKGROUND: Definitions are essential for effective communication and discourse, particularly in science. They allow the shared understanding of a thought or idea, generalization of knowledge, and comparison across scientific investigation. The current terms describing olfactory dysfunction are vague and overlapping. SUMMARY: As a group of clinical olfactory researchers, we propose the standardization of the terms "dysosmia," "anosmia," "hyposmia," "normosmia," "hyperosmia," "olfactory intolerance," "parosmia," and "phantosmia" (or "olfactory hallucination") in olfaction-related communication, with specific definitions in this text. KEY MESSAGES: The words included in this paper were determined as those which are most frequently used in the context of olfactory function and dysfunction, in both clinical and research settings. Despite widespread use in publications, however, there still exists some disagreement in the literature regarding the definitions of terms related to olfaction. Multiple overlapping and imprecise terms that are currently in use are confusing and hinder clarity and universal understanding of these concepts. There is a pressing need to have a unified agreement on the definitions of these olfactory terms by researchers working in the field of chemosensory sciences. With the increased interest in olfaction, precise use of these terms will improve the ability to integrate and advance knowledge in this field

Thermal Properties of Graphene, Carbon Nanotubes and Nanostructured Carbon Materials

Recent years witnessed a rapid growth of interest of scientific and engineering communities to thermal properties of materials. Carbon allotropes and derivatives occupy a unique place in terms of their ability to conduct heat. The room-temperature thermal conductivity of carbon materials span an extraordinary large range - of over five orders of magnitude - from the lowest in amorphous carbons to the highest in graphene and carbon nanotubes. I review thermal and thermoelectric properties of carbon materials focusing on recent results for graphene, carbon nanotubes and nanostructured carbon materials with different degrees of disorder. A special attention is given to the unusual size dependence of heat conduction in two-dimensional crystals and, specifically, in graphene. I also describe prospects of applications of graphene and carbon materials for thermal management of electronics.Comment: Review Paper; 37 manuscript pages; 4 figures and 2 boxe