A comparative study of rare earth metals recovery by bacteria and algae

Portuguese Foundation for Science and Technology (FCT) under the scope of the research project PTDC/AAG-TEC/5269/2014, the strategic funding of UID/BIO/04469/2013 unit and COMPETE 2020 (POCI-01-0145-FEDER-006684) and BioTecNorte operation (NORTE - 01 - 0145 - FEDER - 000004) funded by the European Regional Development Fund under the scope of Norte2020 - Programa Operacional Regional do Norteinfo:eu-repo/semantics/publishedVersio

Local inflammation, lethality and cytokine release in mice injected with Bothrops atrox venom.

We have provided evidence that: (a) lethality of mice to crude Bothrops venom varies according the isogenic strain (A/J > C57Bl/6 > A/Sn > BALB/c > C3H/HePas > DBA/2 > C3H/He); (b)BALB/c mice (LD50=100.0 microg) were injected i.p. with 50 microg of venom produced IL-6, IL-10, INF-gamma, TNF-alpha and NO in the serum. In vitro the cells from the mice injected and challenged with the venom only released IL-10 while peritoneal macrophages released IL-10, INF-gamma and less amounts of IL-6; (c) establishment of local inflammation and necrosis induced by the venom, coincides with the peaks of TNF-alpha, IFN-gamma and NO and the damage was neutralized when the venom was incubated with a monoclonal antibody against a 60 kDa haemorrhagic factor. These results suggest that susceptibility to Bothrops atrox venom is genetically dependent but MHC independent; that IL-6, IL-10, TNF-alpha, IFN-gamma and NO can be involved in the mediation of tissue damage; and that the major venom component inducers of the lesions are haemorrhagins

Mist and Edge Computing Cyber-Physical Human-Centered Systems for Industry 5.0: A Cost-Effective IoT Thermal Imaging Safety System

While many companies worldwide are still striving to adjust to Industry 4.0 principles, the transition to Industry 5.0 is already underway. Under such a paradigm, Cyber-Physical Human-centered Systems (CPHSs) have emerged to leverage operator capabilities in order to meet the goals of complex manufacturing systems towards human-centricity, resilience and sustainability. This article first describes the essential concepts for the development of Industry 5.0 CPHSs and then analyzes the latest CPHSs, identifying their main design requirements and key implementation components. Moreover, the major challenges for the development of such CPHSs are outlined. Next, to illustrate the previously described concepts, a real-world Industry 5.0 CPHS is presented. Such a CPHS enables increased operator safety and operation tracking in manufacturing processes that rely on collaborative robots and heavy machinery. Specifically, the proposed use case consists of a workshop where a smarter use of resources is required, and human proximity detection determines when machinery should be working or not in order to avoid incidents or accidents involving such machinery. The proposed CPHS makes use of a hybrid edge computing architecture with smart mist computing nodes that processes thermal images and reacts to prevent industrial safety issues. The performed experiments show that, in the selected real-world scenario, the developed CPHS algorithms are able to detect human presence with low-power devices (with a Raspberry Pi 3B) in a fast and accurate way (in less than 10 ms with a 97.04% accuracy), thus being an effective solution that can be integrated into many Industry 5.0 applications. Finally, this article provides specific guidelines that will help future developers and managers to overcome the challenges that will arise when deploying the next generation of CPHSs for smart and sustainable manufacturing.Comment: 32 page

Pecuária de corte e a conservação do Pantanal.

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Fast-track referral for health interventions during pregnancy: study protocol of a randomised pragmatic experimental study to reduce low birth weight in Portugal (STOP LBW)

Introduction Low birth weight (LBW) is associated with a wide range of short-term and long-term consequences and is related to maternal psychosocial and behavioural determinants. The objective of this study is to estimate the effect of implementing fast-track referral for early intervention on psychosocial and behavioural risk factors—smoking, alcohol consumption, depression and physical violence—in reducing the incidence of LBW. Methods and analysis Parallel superiority pragmatic clinical trial randomised by clusters. Primary healthcare units (PHCU) located in Portugal will be randomised (1:1) to intervention or control groups. Pregnant women over 18 years of age attending these PHCU will be eligible to the study. Risk factors will be assessed through face-to-face interviews. In the intervention group, women who report at least one risk factor will have immediate access to referral services. The comparison group will be the local standard of care for these risk factors. We will use intention-to-treat analyses to compare intervention and control groups. We estimated a sample size of 2832 pregnant women to detect a 30% reduction in the incidence rate of LBW between the control and intervention groups. Secondary outcomes are the reduction of preterm births, reduction of the four risk factors and acceptance of the intervention. Ethics and dissemination The study was approved by the Ethics Committee of the Public Health Institute of the University of Porto (no CE20140). The findings will be disseminated to the public, the funders, health professionals, health managers and other researchers.This project was funded by the Calouste Gulbenkian Foundation under the Knowledge Challenge 'The Importance of the Right Weight at Birth'. Sponsor contact information: HB. ISPUP. [email protected]

Nitrogen Fertilization and Harvest Management Improve Forage and Crude Protein Content in Crabgrass

Crabgrass (Digitaria spp.) is an annual summer grass that can provide high-quality forage, but optimal management strategies are unclear. Our objective was to compare the yield and quality of crabgrass (Mojo and Quick-N-Big) under different nitrogen rates and harvest management. The experimental design was a randomized complete block with five treatments and three replications for each crabgrass variety, totaling fifteen experimental units for both Mojo and Quick-N-Big, in adjacent sites. Treatments were nitrogen rates (0, 100, and 200 lb N/acre) and harvest management (cut once or twice per year) for two growing seasons (2020 and 2021). Total forage accumulation (TFA) increased with nitrogen fertilization for both cultivars. Mojo had the highest TFA in the first year (7000 lb DM/a/yr) while Quick-N-Big TFA was the highest in the second year (7635 lb DM/a/yr). The highest crude protein (CP) content was obtained with the highest N dose, ranging from 10.5 to 13% for both cultivars. Based on these results, N fertilization and harvest management can contribute to improving forage yield and crude protein of crabgrass varieties during the growing season in forage systems

Uma análise do discurso sobre a temática acesso aberto nos anais do EDICIC Ibérico no período de 2013 a 2017

Objective. It was intended to analyze the concept of open access and to observe if there is any relation with the concept of access to information as an ethical supravalue; as specific objectives, a) it was sought to investigate the presence of the terms "open access" and "open data" in the events of the EDICIC and its thematic relevance for the event, and b) to divulge the analyzed concepts and highlight their importance for the scientific development. Method. It was used as research source the records of the Iberian EDICIC available in open access, that is, those occurring in the period 2013-2017. The search terms applied were "open access" and "open data", in addition to their respective ones in Spanish and Portuguese, present in the title, abstract and keywords. The corpus generated a total of 26 articles, which was later analyzed, using Discourse Analysis as a method. Results. As results, it was possible to reach a group of 09 ethical instances, identified from the authors' discourse when they talk about the concepts of Open Science and its importance for scientific development. Conclusions. Open access has brought significant changes in the dissemination of scientific research, government data and academic research. However, one can see that the main factor governing the whole movement is open access in a free, egalitarian way and guaranteeing constitutional rights, thus evoking the ethical aspect that this premise involves

New optimal tests of quantum nonlocality

We explore correlation polytopes to derive a set of all Boole-Bell type conditions of possible classical experience which are both maximal and complete. These are compared with the respective quantum expressions for the Greenberger-Horne-Zeilinger (GHZ) case and for two particles with spin state measurements along three directions.Comment: 10 page