Contextual-based Image Inpainting: Infer, Match, and Translate

We study the task of image inpainting, which is to fill in the missing region of an incomplete image with plausible contents. To this end, we propose a learning-based approach to generate visually coherent completion given a high-resolution image with missing components. In order to overcome the difficulty to directly learn the distribution of high-dimensional image data, we divide the task into inference and translation as two separate steps and model each step with a deep neural network. We also use simple heuristics to guide the propagation of local textures from the boundary to the hole. We show that, by using such techniques, inpainting reduces to the problem of learning two image-feature translation functions in much smaller space and hence easier to train. We evaluate our method on several public datasets and show that we generate results of better visual quality than previous state-of-the-art methods.Comment: ECCV 2018 camera read

Sunjammer

No abstract available

Dual Band Electrodes in Generator-Collector Mode: Simultaneous Measurement of Two Species

A computational model for the simulation of a double band collector-generator experiment is applied to the situation where two electrochemical reactions occur concurrently. It is shown that chronoamperometric measurements can be used to take advantage of differences in diffusion coefficients to measure the concentrations of both electroactive species simultaneously, by measuring the time at which the collection efficiency reaches a specific value. The separation of the electrodes is shown to not affect the sensitivity of the method (in terms of percentage changes in the measured time to reach the specified collection efficiency), but wider gaps can provide a greater range of (larger) absolute values of this characteristic time. It is also shown that measuring the time taken to reach smaller collection efficiencies can allow for the detection of smaller amounts of whichever species diffuses faster. The case of a system containing both ascorbic acid and opamine in water is used to exemplify the method, and it is shown that mole fractions of ascorbic acid between 0.055 and 0.96 can, in principle, be accurately measured.Comment: 34 pages, 8 figure

Spatially and polarization resolved plasmon mediated transmission through continuous metal films

The experimental demonstration and characterization is made of the plasmon-mediated resonant transmission through an embedded undulated continuous thin metal film under normal incidence. 1D undulations are shown to enable a spatially resolved polarisation filtering whereas 2D undulations lead to spatially resolved, polarization independent transmission. Whereas the needed submicron microstructure lends itself in principle to CD-like low-cost mass replication by means of injection moulding and embossing, the present paper demonstrates the expected transmission effects on experimental models based on metal-coated photoresist gratings. The spectral and angular dependence in the neighbourhood of resonance are investigated and the question of the excess losses exhibited by surface plasmons is discusse

The exponential map for the unitary group SU(2,2)

In this article we extend our previous results for the orthogonal group, $SO(2,4)$, to its homomorphic group $SU(2,2)$. Here we present a closed, finite formula for the exponential of a $4\times 4$ traceless matrix, which can be viewed as the generator (Lie algebra elements) of the $SL(4,C)$ group. We apply this result to the $SU(2,2)$ group, which Lie algebra can be represented by the Dirac matrices, and discuss how the exponential map for $SU(2,2)$ can be written by means of the Dirac matrices.Comment: 10 page

Plus \ue7a change? Switching lithium preparations

Copyright \ua9 The Author(s), 2022. Published by Cambridge University Press on behalf of the Royal College of Psychiatrists. Aims and method A supply disruption alert in 2020, now rescinded, notified UK prescribers of the planned discontinuation of Priadel\uae (lithium carbonate) tablets. This service evaluation explored lithium dose and plasma levels before and after the switching of lithium brands, in order to determine the interchangeability of different brands of lithium from a pharmacokinetic perspective. Results Data on the treatment of 37 patients switched from Priadel\uae tablets were analysed. Switching to Camcolit\uae controlled-release tablets at the same dose did not result in meaningful differences in plasma lithium levels. Dose adjustment and known or suspected poor medication adherence were associated with greater variability in plasma lithium levels on switching brands. Clinical implications For comparable pre- and post-switch doses in adherent patients, the most common brands of lithium carbonate appear to produce similar plasma lithium levels. British National Formulary guidance relating to switching lithium brands may be unnecessarily complex

Triangulating Abuse Liability Assessment for Flavoured Cigar Products Using Physiological, Behavioural Economic and Subjective Assessments: A Within-subjects Clinical Laboratory Protocol

Introduction In the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products are permitted. Such flavourings influence positive perceptions of tobacco products and are linked to increased use. Flavourings may mask the taste of tobacco and enhance smoke inhalation, influencing toxicant exposure and abuse liability among novice tobacco users. Using clinical laboratory methods, this study investigates how flavour availability affects measures of abuse liability in young adult cigarette smokers. The specific aims are to evaluate the effect of cigar flavours on nicotine exposure, and behavioural and subjective measures of abuse liability. Methods and analyses Participants (projected n=25) are healthy smokers of five or more cigarettes per day over the past 3 months, 18–25 years old, naive to cigar use (lifetime use of 50 or fewer cigar products and no more than 10 cigars smoked in the past 30 days) and without a desire to quit cigarette smoking in the next 30 days. Participants complete five laboratory sessions in a Latin square design with either their own brand cigarette or a session-specific Black & Mild cigar differing in flavour (apple, cream, original and wine). Participants are single-blinded to cigar flavours. Each session consists of two 10-puff smoking bouts (30 s interpuff interval) separated by 1 hour. Primary outcomes include saliva nicotine concentration, behavioural economic task performance and response to various questionnaire items assessing subjective effects predictive of abuse liability. Differences in outcomes across own brand cigarette and flavoured cigar conditions will be tested using linear mixed models

The MAP Satellite Feed Horns

We present the design, manufacturing methods, and characterization of 20 microwave feed horns currently in use on the Microwave Anisotropy Probe (MAP) satellite. The nature of the cosmic microwave background (CMB) anisotropy requires a detailed understanding of the properties of every optical component of a microwave telescope. In particular, the properties of the feeds must be known so that the forward gain and sidelobe response of the telescope can be modeled and so that potential systematic effects may be computed. MAP requires low emissivity, azimuthally symmetric, low-sidelobe feeds in five microwave bands (K, Ka, Q, V, and W) that fit within a constrained geometry. The beam pattern of each feed is modeled and compared with measurements; the agreement is generally excellent to the -60 dB level (80 degrees from the beam peak). This agreement verifies the beam-predicting software and the manufacturing process. The feeds also affect the properties and modeling of the microwave receivers. To this end, we show that the reflection from the feeds is less than -25 dB over most of each band and that their emissivity is acceptable. The feeds meet their multiple requirements.Comment: 9 pages with 7 figures, of which 2 are in low-resolution versions; paper is available with higher quality figures at http://map.gsfc.nasa.gov/m_mm/tp_links.htm

Bi-layer splitting in overdoped high TcT_{c} cuprates

Recent angle-resolved photoemission data for overdoped Bi2212 are explained. Of the peak-dip-hump structure, the peak corresponds the $\vec q =0$ component of a hole condensate which appears at $T_c$. The fluctuating part of this same condensate produces the hump. The bilayer splitting is large enough to produce a bonding hole and an electron antibonding quasiparticle Fermi surface. Smaller bilayer splittings observed in some experiments reflect the interaction of the peak structure with quasiparticle states near, but not at, the Fermi surface.Comment: 4 pages with 2 figures - published versio

Partially Open HIV-1 Envelope Structures Exhibit Conformational Changes Relevant for Coreceptor Binding and Fusion

HIV-1 Env, a trimer of gp120-gp41 heterodimers, mediates membrane fusion after binding host receptor CD4. Receptor binding displaces V1V2 loops from Env's apex, allowing coreceptor binding and opening Env to enable gp41-mediated fusion. We present 3.54 Å and 4.06 Å cryoelectron microscopy structures of partially open soluble native-like Env trimers (SOSIPs) bound to CD4. One structure, a complex with a coreceptor-mimicking antibody that binds both CD4 and gp120, stabilizes the displaced V1V2 and reveals its structure. Comparing partially and fully open Envs with closed Envs shows that gp41 rearrangements are independent of the CD4-induced rearrangements that result in V1V2 displacement and formation of a 4-stranded bridging sheet. These findings suggest ordered conformational changes before coreceptor binding: (1) gp120 opening inducing side-chain rearrangements and a compact gp41 central helix conformation, and (2) 4-stranded bridging-sheet formation and V1V2 displacement. These analyses illuminate potential receptor-induced Env changes and inform design of therapeutics disrupting viral entry