6,381 research outputs found
Schwarzschild-anti de Sitter within an Isothermal Cavity: Thermodynamics, Phase Transitions and the Dirichlet Problem
The thermodynamics of Schwarzschild black holes within an isothermal cavity
and the associated Euclidean Dirichlet boundary-value problem are studied for
four and higher dimensions in anti-de Sitter (AdS) space. For such boundary
conditions classically there always exists a unique hot AdS solution and two or
no Schwarzschild-AdS black-hole solutions depending on whether or not the
temperature of the cavity-wall is above a minimum value, the latter being a
function of the radius of the cavity. Assuming the standard area-law of
black-hole entropy, it was known that larger and smaller holes have positive
and negative specific heats and hence are locally thermodynamically stable and
unstable respectively. In this paper we present the first derivation of this by
showing that the standard area law of black-hole entropy holds in the
semi-classical approximation of the Euclidean path integral for such boundary
conditions. We further show that for wall-temperatures above a critical value a
phase transition takes hot AdS to the larger Schwarzschild-AdS within the
cavity. The larger hole thus can be globally thermodynamically stable above
this temperature. The phase transition can occur for a cavity of arbitrary
radius above a (corresponding) critical temperature. In the infinite cavity
limit this picture reduces to that considered by Hawking and Page. The case of
five dimensions is found to be rather special since exact analytic expressions
can be obtained for the masses of the two holes as functions of cavity radius
and temperature thus solving exactly the Euclidean Dirichlet problem. This
makes it possible to compute the on-shell Euclidean action as functions of them
from which other quantities of interest can be evaluated exactly.Comment: 23 pages, Late
Systems, interactions and macrotheory
A significant proportion of early HCI research was guided by one very clear vision: that the existing theory base in psychology and cognitive science could be developed to yield engineering tools for use in the interdisciplinary context of HCI design. While interface technologies and heuristic methods for behavioral evaluation have rapidly advanced in both capability and breadth of application, progress toward deeper theory has been modest, and some now believe it to be unnecessary. A case is presented for developing new forms of theory, based around generic âsystems of interactors.â An overlapping, layered structure of macro- and microtheories could then serve an explanatory role, and could also bind together contributions from the different disciplines. Novel routes to formalizing and applying such theories provide a host of interesting and tractable problems for future basic research in HCI
Local variation in helminth burdens of Egyptian spiny mice (Acomys cahirinus dimidiatus) from ecologically similar sites: relationships with hormone concentrations and social behaviour
Populations of Egyptian spiny mice (Acomys cahirinus dimidiatus) in a fragmented montane wadi system in the Sinai showed significant differences in the abundance of gut helminths. Differences in parasite load between populations were positively associated with measures of androgen activity but showed no significant relationship with glucocorticoid activity. Social discrimination tests with adult males from different wadis showed that those from sites with greater helminth abundance were less likely to investigate odours from other males and were less aggressive when subsequently interacting with the odour donors. Subjects showed markedly more investigation towards the odours of males from distant wadis compared with those from their own or immediately neighbouring wadi, but were less aggressive when confronted with odour donors from distant wadis. Despite this, there was a positive relationship between the amount of investigation towards distant male odour and subsequent aggression towards the male. While aggressiveness was positively associated with measures of androgen and glucocorticoid activity, no significant relationship emerged with individual helminth infection. Thus aggressiveness appeared to relate to overall local population levels of infection rather than individual challenge
Multiplex Touchdown PCR for Rapid Typing of the Opportunistic Pathogen Propionibacterium acnes
The opportunistic human pathogen Propionibacterium acnes is composed of a number of distinct phylogroups, designated types IA(1), IA(2), IB, IC, II, and III, which vary in their production of putative virulence factors, their inflammatory potential, and their biochemical, aggregative, and morphological characteristics. Although multilocus sequence typing (MLST) currently represents the gold standard for unambiguous phylogroup classification and individual strain identification, it is a labor-intensive and time-consuming technique. As a consequence, we developed a multiplex touchdown PCR assay that in a single reaction can confirm the species identity and phylogeny of an isolate based on its pattern of reaction with six primer sets that target the 16S rRNA gene (all isolates), ATPase (types IA(1), IA(2), and IC), sodA (types IA(2) and IB), atpD (type II), and recA (type III) housekeeping genes, as well as a Fic family toxin gene (type IC). When applied to 312 P. acnes isolates previously characterized by MLST and representing types IA(1) (n = 145), IA(2) (n = 20), IB (n = 65), IC (n = 7), II (n = 45), and III (n = 30), the multiplex displayed 100% sensitivity and 100% specificity for detecting isolates within each targeted phylogroup. No cross-reactivity with isolates from other bacterial species was observed. This multiplex assay will provide researchers with a rapid, high-throughput, and technically undemanding typing method for epidemiological and phylogenetic investigations. It will facilitate studies investigating the association of lineages with various infections and clinical conditions, and it will serve as a prescreening tool to maximize the number of genetically diverse isolates selected for downstream higher-resolution sequence-based analyses
Submerged in the mainstream? A case study of an immigrant learner in a New Zealand primary classroom
Immigrant children from diverse language backgrounds face not only linguistic challenges when enrolled in mainstream English-medium classrooms, but also difficulties adjusting to an unfamiliar learning community. The culture of primary school classrooms in New Zealand typically reflects conventions across three dimensions: interactional, instructional task performance and cognitive-academic development. All three dimensions are underpinned by the culturally specific discourse conventions involved in language socialisation. New learners may be helped by classmates or their teacher to understand and successfully use these conventions, but left on their own they may sink rather than swim. This is a case study of one Taiwanese 11-year old boy, 'John', who entered a New Zealand primary classroom midway through the school year. John's basic conversational ability was sound, but he did not possess the interactive classroom skills needed to operate in the new culture of learning. Selected from a wider study of the classroom, transcript data from audio-recorded excerpts of John's interactions over several months with his teacher and classmates are interpreted from perspectives derived from sociocultural and language socialisation theories. The article concludes with a brief consideration of the extent to which John constructed, or was constrained from constructing meaningful learning experiences, and suggestions for further research and reflection
C stars in the outer spheroid of NGC 6822
From a 2 x 2 degree survey of NGC 6822 we have previously established that
this Local Group dwarf irregular galaxy possesses a huge spheroid having more
than one degree in length. This spheroid is in rotation but its rotation curve
is known only within ~15' from the center. It is therefore critical to identify
bright stars belonging to the spheroid to characterize, as far as possible, its
outer kinematics. We use the new wide field near infrared imager CPAPIR,
operated by the SMARTS consortium, to acquire J, Ks images of two 34.8' x 34.8'
areas in the outer spheroid to search for C stars. The colour diagram of the
fields allows the identification of 192 C stars candidates but a study of the
FWHM of the images permits the rejection of numerous non-stellar objects with
colours similar to C stars. We are left with 75 new C stars, their mean Ks
magnitude and mean colour are similar to the bulk of known NGC 6822 C stars.
This outer spheroid survey confirms that the intermediate-age AGB stars are a
major contributor to the stellar populations of the spheroid. The discovery of
some 50 C stars well beyond the limit of the previously known rotation curve
calls for a promising spectroscopic follow-up to a major axis distance of 40'.Comment: 13 page
Rapid Quantification of Molecular Diversity for Selective Database Acquisition
There is an increasing need to expand the structural diversity of the molecules investigated in lead-discovery programs. One way in which this can be achieved is by acquiring external datasets that will enhance an existing database. This paper describes a rapid procedure for the selection of external datasets using a measure of structural diversity that is calculated from sums of pairwise intermolecular structural similarities
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Ultralow-threshold, continuous-wave upconverting lasing from subwavelength plasmons.
Miniaturized lasers are an emerging platform for generating coherent light for quantum photonics, in vivo cellular imaging, solid-state lighting and fast three-dimensional sensing in smartphones1-3. Continuous-wave lasing at room temperature is critical for integration with opto-electronic devices and optimal modulation of optical interactions4,5. Plasmonic nanocavities integrated with gain can generate coherent light at subwavelength scales6-9, beyond the diffraction limit that constrains mode volumes in dielectric cavities such as semiconducting nanowires10,11. However, insufficient gain with respect to losses and thermal instabilities in nanocavities has limited all nanoscale lasers to pulsed pump sources and/or low-temperature operation6-9,12-15. Here, we show continuous-wave upconverting lasing at room temperature with record-low thresholds and high photostability from subwavelength plasmons. We achieve selective, single-mode lasing from Yb3+/Er3+-co-doped upconverting nanoparticles conformally coated on Ag nanopillar arrays that support a single, sharp lattice plasmon cavity mode and greater than wavelength λ/20 field confinement in the vertical dimension. The intense electromagnetic near-fields localized in the vicinity of the nanopillars result in a threshold of 70âWâcm-2, orders of magnitude lower than other small lasers. Our plasmon-nanoarray upconverting lasers provide directional, ultra-stable output at visible frequencies under near-infrared pumping, even after six hours of constant operation, which offers prospects in previously unrealizable applications of coherent nanoscale light
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