519 research outputs found

    Jane Austen\u27s use of the epistolary method

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    There is . . . a prominent use of letters within the novels of Jane Austen. It has been shown that she wao influenced by Samuel Richardson and Fanny Burney and that she had a long experimental period of almost exclusive use of the epistolary method. It is from their influence and from her experimentation that the six major novels evolved; this supreme achievement was to give their creator a prominent place in the history of the English novel. No one factor can be cited as Miss Austen \u27s outstanding contribution, for each novel is a synthesis of many superior qualities. The letters, however, so prominently and effectively used within the novels have been considered here as one substantial reason for her success

    Lernen durch Kulturkontakt. Eine Prozeßanalyse der Akkulturation deutscher Studienreferendare in multikuturellen Klassen

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    Ein Ziel der qualitativen Längsschnittuntersuchung ist die inhaltsanalytische Rekonstruktion der Unterschiede individueller Veränderungen bei deutschen Studienreferendaren, die während ihres Referendariats einem kontinuierlichen Kontakt mit Schülern anderer kultureller Orientierungen ausgesetzt sind. Es wird von der Annahme ausgegangen, daß die Struktur und Richtung von Veränderungen abhängig davon sind, inwieweit es den Referendaren gelingt, unverträgliche kulturelle Validitäten eigener Verhaltensweisen und derjenigen von Schülern mit anderen kulturellen Orientierungen kognitiv und affektiv zu verarbeiten, und welche Interkulturalitätsstrategie sie wählen. Dargestellt werden die vor Beginn des Referendariats erwarteten eigenen Veränderungen der Referendare durch Kulturkontakt, ihre Veränderungen durch ihre Erfahrungen nach dessen Beendigung sowie solche, die sich in einer tutoriell gelenkten Auseinandersetzung mit fremdkulturellen Sichtweisen ermitteln ließen. Es lassen sich deutliche Unterschiede in den Akkulturationsverläufen feststellen. Die mit der Erfahrung zunehmende kognitive Differenzierung im Umgang mit kulturbezogenen Phänomenen wird mehrheitlich als Chance für individuelle Veränderungen gewertet. (DIPF/Orig.)One of the aims of this qualitative longitudinal study focusing on novice teachers is the contentanalytic reconstruction of the differences in individual changes triggered by continuous contact with students of another cultural background in multicultural schools. The underlying hypothesis is that the structure and direction of changes depends on the young teacher\u27s ability to cope both cognitively and affectively with incompatible cultural validities in their own behavior and in that of students of a different cultural background as well as on the intercultural strategy chosen. The authors sketch the personal changes through cultural contact expected by the beginning teachers before starting their practical training, the changes resulting from the experiences made during that time as they manifest themselves at the end of training phase, and those changes which could be detected in tutorially guided discussions of foreign cultural positions. The results show clear differences in the acculturation processes. By the majority, the increase in cognitive differentiation resulting from experiences made in dealing with cultural phenomena is regarded as an opportunity for personal change. (DIPF/Orig.

    The Lantern Vol. 32, No. 3, Summer 1966

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    • Commandment Point • The Descendant • The Ultimate Journey • Thoughts While Riding New York Subway • Crazy Arthur • Confession • The Gull • One Boy • Cinquain: Cruel Life • Quality of Revenge • The Bull • Chinese Landscapehttps://digitalcommons.ursinus.edu/lantern/1089/thumbnail.jp

    Social Protection in Ghana and Kenya through an Inclusive Development Lens: complex effects and risks

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    This paper analyzes the complex effects and risks of social protection programmes in Ghana and Kenya on poor people’s human wellbeing, voice and empowerment and interactions with the social protection regulatory framework and policy instruments. For this purpose, it adopts a comprehensive Inclusive Development framework to systematically explore the complex effects of cash transfers and health insurance at the individual, household and community level. The findings highlight the positive provisionary and preventive effects of social protection, but also illustrate that the poorest are still excluded and that promotive effects, in the form of enhanced productivity, manifest themselves mainly for the people who are less resource poor. They can build more effectively upon an existing asset base, capabilities, power and social relations to counter the exclusionary mechanisms of the system, address inequity concerns and offset the transaction costs of accessing and benefitting from social protection. The inclusive development framework enables to lay these complex effects and interactions bear, and points to areas that require more longitudinal and mixed methodology research

    The Lantern Vol. 32, No. 2, January 1966

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    • Mission 63 • The Kiss • The Dream • Silence is Golden • Self-Pity • The Excuse • Car Eighteen • Clothes Make the Man • The Place of a Just Man • Golden Gods • The Journey • Third Prize Picture • Gone Now • In Vain • Deep Dying • Marnie • Ruthttps://digitalcommons.ursinus.edu/lantern/1088/thumbnail.jp

    The Lantern Vol. 33, No. 2, May 1967

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    • The Plea • Arrival • Nouvelle • Poem on Theme by Leroi Jones • Night Thoughts • Finals • Caught in the Act • Tomorrow • The Rail • The Price • Lost • It\u27s a Svaden Spring • No Thanks to City Hall • Grinding Them to Dust • Four • Five • Nine • Ten • Twelve • Thirty-Six • Psyched Up and Out • Gutted Gloryhttps://digitalcommons.ursinus.edu/lantern/1091/thumbnail.jp

    Broad Down, Devon: archaeological and other stories

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    publication-status: PublishedThis is a post-print, author-produced version of an article accepted for publication Journal of Material Culture, 2010, Vol. 15, Issue 3, pp. 345 - 367. Copyright © 2010 SAGE Publications. The definitive publisher-authenticated version is available online at http://mcu.sagepub.com/content/15/3/345.shortThis article explores the knowledge construction process of an archaeological site in East Devon, UK. Bouncing off an oral historical account of the site that seems to run against scientific truth claims, the author investigates the story of how knowledge of the site has developed over the last two centuries. Building on previous work that explores the history and practice of archaeology, the article opens up questions of what counts as evidence. Then, taking a cue from more recent work that suggests a more dynamic and open-ended engagement with the landscape, the article turns to examine how the meaning of a site can be made and remade. As part of this endeavour, questions of what as well as who can ‘speak’ are examined and some space is opened up for the agency of ‘minor figures’, both human and non-human

    The Lantern Vol. 33, No. 1, Spring 1967

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    • The Implement • A Broken Backstop • City • My Friend Is • Meditation on Eight Dead Nurses and a Mad Austin Sniper • Fact and Fancy • Valhalla • A Blandishment • You Say You Were a Name So Sweet • Preview Rerun • To Lynne • Shards • The Initial Error • Daniel • Gold on Gold • If Morning Ever Comes • Third Poem to Tonya • The Kiss • Her Soul Was Slippery • Quietlyhttps://digitalcommons.ursinus.edu/lantern/1090/thumbnail.jp

    Astrometry with the Hubble Space Telescope: Trigonometric Parallaxes of Selected Hyads

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    We present absolute parallaxes and proper motions for seven members of the Hyades open cluster, pre-selected to lie in the core of the cluster. Our data come from archival astrometric data from FGS 3, and newer data for 3 Hyads from FGS 1R, both white-light interferometers on the Hubble Space Telescope (HST). We obtain member parallaxes from six individual Fine Guidance Sensor (FGS) fields and use the field containing van Altena 622 and van Altena 627 (= HIP 21138) as an example. Proper motions, spectral classifications and VJHK photometry of the stars comprising the astrometric refer- ence frames provide spectrophotometric estimates of reference star absolute parallaxes. Introducing these into our model as observations with error, we determine absolute parallaxes for each Hyad. The parallax of vA 627 is significantly improved by including a perturbation orbit for this previously known spectroscopic binary, now an astrometric binary. Compared to our original (1997) determina- tions, a combination of new data, updated calibration, and improved analysis lowered the individual parallax errors by an average factor of 4.5. Comparing parallaxes of the four stars contained in the Hipparcos catalog, we obtain an average factor of 11 times improvement with the HST . With these new results, we also have better agreement with Hipparcos for the four stars in common. These new parallaxes provide an average distance for these seven members, = 47.5 pc, for the core a \pm 1 - {\sigma} dispersion depth of 3.6 pc, and a minimum depth from individual components of 16.0 \pm 0.9 pc. Absolute magnitudes for each member are compared to established main sequences, with excellent agreement. We obtain a weighted average distance modulus for the core of the Hyades of m-M=3.376 \pm 0.01, a value close to the previous Hipparcos values, m-M=3.33\pm 0.02.Comment: 21 pages, 7 figures, Astronomical Journal, accepted 2011-3-

    Multiplatform molecular profiling identifies potentially targetable biomarkers in malignant phyllodes tumors of the breast.

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    Malignant phyllodes tumor is a rare breast malignancy with sarcomatous overgrowth and with limited effective treatment options for recurrent and metastatic cases. Recent clinical trials indicated a potential for anti-angiogenic, anti-EGFR and immunotherapeutic approaches for patients with sarcomas, which led us to investigate these and other targetable pathways in malignant phyllodes tumor of the breast. Thirty-six malignant phyllodes tumors (including 8 metastatic tumors with two cases having matched primary and metastatic tumors) were profiled using gene sequencing, gene copy number analysis, whole genome expression, and protein expression. Whole genome expression analysis demonstrated consistent over-expression of genes involved in angiogenesis including VEGFA, Angiopoietin-2, VCAM1, PDGFRA, and PTTG1. EGFR protein overexpression was observed in 26/27 (96%) of cases with amplification of the EGFR gene in 8/24 (33%) cases. Two EGFR mutations were identified including EGFRvIII and a presumed pathogenic V774M mutation, respectively. The most common pathogenic mutations included TP53 (50%) and PIK3CA (15%). Cases with matched primary and metastatic tumors harbored identical mutations in both sites (PIK3CA/KRAS and RB1 gene mutations, respectively). Tumor expression of PD-L1 immunoregulatory protein was observed in 3/22 (14%) of cases. Overexpression of molecular biomarkers of increased angiogenesis, EGFR and immune checkpoints provides novel targeted therapy options in malignant phyllodes tumors of the breast
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